MX2019007615A - Imagenología de celulas tumorales e inmunitarias basadas en expresion de pd-l1. - Google Patents
Imagenología de celulas tumorales e inmunitarias basadas en expresion de pd-l1.Info
- Publication number
- MX2019007615A MX2019007615A MX2019007615A MX2019007615A MX2019007615A MX 2019007615 A MX2019007615 A MX 2019007615A MX 2019007615 A MX2019007615 A MX 2019007615A MX 2019007615 A MX2019007615 A MX 2019007615A MX 2019007615 A MX2019007615 A MX 2019007615A
- Authority
- MX
- Mexico
- Prior art keywords
- tumor
- expression
- immune cell
- cell imaging
- imaging based
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
- A61K49/0056—Peptides, proteins, polyamino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/14—Peptides, e.g. proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasonic imaging preparations
- A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/225—Microparticles, microcapsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Radiology & Medical Imaging (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acoustics & Sound (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662438575P | 2016-12-23 | 2016-12-23 | |
| US201762519534P | 2017-06-14 | 2017-06-14 | |
| PCT/US2017/068025 WO2018119313A1 (en) | 2016-12-23 | 2017-12-21 | Tumor and immune cell imaging based on pd-l1 expression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019007615A true MX2019007615A (es) | 2019-11-05 |
Family
ID=62627749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019007615A MX2019007615A (es) | 2016-12-23 | 2017-12-21 | Imagenología de celulas tumorales e inmunitarias basadas en expresion de pd-l1. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11607466B2 (https=) |
| EP (1) | EP3558395A4 (https=) |
| JP (3) | JP7784103B2 (https=) |
| KR (2) | KR20240023665A (https=) |
| CN (1) | CN110366432A (https=) |
| AU (1) | AU2017382282B9 (https=) |
| BR (1) | BR112019012986A2 (https=) |
| CA (1) | CA3048229A1 (https=) |
| IL (1) | IL267572B2 (https=) |
| MX (1) | MX2019007615A (https=) |
| WO (1) | WO2018119313A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119264211A (zh) | 2018-08-27 | 2025-01-07 | 瑞泽恩制药公司 | 拉曼光谱在下游纯化中的应用 |
| CN109512798B (zh) * | 2019-01-15 | 2022-05-13 | 南京从一医药科技有限公司 | 一种用于抗肿瘤免疫治疗的药物组合物纳米体系 |
| CN111662270A (zh) * | 2019-03-05 | 2020-09-15 | 中国医学科学院药物研究所 | 碘同位素标记苄苯醚衍生物、及其制法和药物组合物与用途 |
| CN110898234B (zh) * | 2019-12-25 | 2020-12-22 | 河南大学 | 一种二维铋纳米复合材料及其制备方法和应用 |
| TWI833056B (zh) | 2019-12-31 | 2024-02-21 | 財團法人工業技術研究院 | 核酸藥物複合體以及其用途 |
| CN112067586B (zh) * | 2020-06-24 | 2021-08-03 | 江南大学 | 一种基于荧光淬灭拉曼增强的前列腺特异性抗原双信号光谱分析方法 |
| KR20230086657A (ko) * | 2020-08-07 | 2023-06-15 | 더 존스 홉킨스 유니버시티 | 프로그램된 사멸 리간드-1(pd-li) 발현의 영상화 및 표적화 |
| DE102020130954A1 (de) | 2020-11-23 | 2022-05-25 | Universität Duisburg-Essen | Markierungspartikel für Raman-Streuung und/oder Fluoreszenz-Strahlung |
| CN114853851B (zh) * | 2021-02-04 | 2023-08-15 | 南方医科大学南方医院 | 靶向pd-l1多肽探针及其在制备pet显像剂中的应用 |
| CN113341023B (zh) * | 2021-06-30 | 2022-12-23 | 大连医科大学附属第一医院 | 一种基于液质联用的血清二氨基庚二酸的检测试剂盒及检测方法与应用 |
| US20250135047A1 (en) * | 2021-08-06 | 2025-05-01 | The Johns Hopkins University | Improved aluminum fluoride radiosynthesis of [18f]dk222 |
| CN115364247A (zh) * | 2021-09-15 | 2022-11-22 | 中国人民解放军海军军医大学第一附属医院 | 一种靶向显影剂、制备方法及其应用 |
| CN114010655B (zh) * | 2021-11-02 | 2023-02-03 | 安徽医科大学第一附属医院 | 一种识别和降解前列腺癌细胞表面的pd-l1的金纳米星及其制备方法和应用 |
| CN114569745A (zh) * | 2022-03-18 | 2022-06-03 | 哈尔滨医科大学 | 一种靶向pd-l1的多肽pet分子成像探针及其制备方法与应用 |
| CN121889176A (zh) * | 2023-09-20 | 2026-04-17 | Trimt有限责任公司 | 用于体内定向pd-l1表达的功能化肽 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ542371A (en) * | 2003-03-19 | 2008-10-31 | Universitatsspital Basel | Radiolabeled conjugates based on substance P and the uses thereof |
| EP3255060A1 (en) | 2008-12-09 | 2017-12-13 | F. Hoffmann-La Roche AG | Anti-pd-l1 antibodies and their use to enhance t-cell function |
| WO2012074840A2 (en) * | 2010-11-22 | 2012-06-07 | The General Hospital Corporation | Compositions and methods for in vivo imaging |
| WO2013032839A2 (en) | 2011-09-02 | 2013-03-07 | The Board Of Trustees Of The Leland Stanford Junior University | Raman imaging devices and methods of moleclar imaging |
| WO2014043606A1 (en) * | 2012-09-14 | 2014-03-20 | The Johns Hopkins University | Bacteria-specific labeled substrtates as imaging biomarkers to diagnose, locate, and monitor infections |
| US9308236B2 (en) * | 2013-03-15 | 2016-04-12 | Bristol-Myers Squibb Company | Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions |
| WO2016039749A1 (en) * | 2014-09-11 | 2016-03-17 | Bristol-Myers Squibb Company | Macrocyclic inhibitors of the pd-1/pd-l1 and cd80 (b7-1)/pd-li protein/protein interactions |
| CA2969067A1 (en) * | 2014-11-25 | 2016-06-02 | Bristol-Myers Squibb Company | Novel pd-l1 binding polypeptides for imaging |
| US9861680B2 (en) | 2014-12-18 | 2018-01-09 | Bristol-Myers Squibb Company | Immunomodulators |
| US9944678B2 (en) | 2014-12-19 | 2018-04-17 | Bristol-Myers Squibb Company | Immunomodulators |
| US20160222060A1 (en) | 2015-02-04 | 2016-08-04 | Bristol-Myers Squibb Company | Immunomodulators |
| HRP20210644T8 (hr) | 2016-05-19 | 2021-06-25 | Bristol-Myers Squibb Company | Imunomodulatori za pet-snimanje |
| CN107869033B (zh) * | 2016-09-26 | 2020-10-02 | 青岛胶南海尔洗衣机有限公司 | 一种干衣机用正反转风扇及干衣机 |
-
2017
- 2017-12-21 KR KR1020247003223A patent/KR20240023665A/ko not_active Ceased
- 2017-12-21 US US16/471,678 patent/US11607466B2/en active Active
- 2017-12-21 CA CA3048229A patent/CA3048229A1/en active Pending
- 2017-12-21 JP JP2019534737A patent/JP7784103B2/ja active Active
- 2017-12-21 KR KR1020197021481A patent/KR102662725B1/ko active Active
- 2017-12-21 CN CN201780087531.0A patent/CN110366432A/zh active Pending
- 2017-12-21 EP EP17883237.4A patent/EP3558395A4/en active Pending
- 2017-12-21 IL IL267572A patent/IL267572B2/en unknown
- 2017-12-21 AU AU2017382282A patent/AU2017382282B9/en active Active
- 2017-12-21 MX MX2019007615A patent/MX2019007615A/es unknown
- 2017-12-21 BR BR112019012986A patent/BR112019012986A2/pt unknown
- 2017-12-21 WO PCT/US2017/068025 patent/WO2018119313A1/en not_active Ceased
-
2022
- 2022-12-23 JP JP2022207606A patent/JP7680759B2/ja active Active
-
2025
- 2025-04-30 JP JP2025075768A patent/JP2025118743A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP7784103B2 (ja) | 2025-12-11 |
| IL267572B1 (en) | 2024-10-01 |
| EP3558395A4 (en) | 2020-08-12 |
| AU2017382282B9 (en) | 2025-02-13 |
| WO2018119313A1 (en) | 2018-06-28 |
| CN110366432A (zh) | 2019-10-22 |
| JP2025118743A (ja) | 2025-08-13 |
| AU2017382282A1 (en) | 2019-07-11 |
| AU2017382282B2 (en) | 2025-01-30 |
| JP7680759B2 (ja) | 2025-05-21 |
| US11607466B2 (en) | 2023-03-21 |
| CA3048229A1 (en) | 2018-06-28 |
| IL267572B2 (en) | 2025-02-01 |
| JP2023052071A (ja) | 2023-04-11 |
| IL267572A (en) | 2019-08-29 |
| JP2020514278A (ja) | 2020-05-21 |
| KR20190102018A (ko) | 2019-09-02 |
| US20190314531A1 (en) | 2019-10-17 |
| EP3558395A1 (en) | 2019-10-30 |
| BR112019012986A2 (pt) | 2019-12-03 |
| KR20240023665A (ko) | 2024-02-22 |
| KR102662725B1 (ko) | 2024-04-30 |
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