MX385304B - Nuevos complejos metálicos de nocardamina y su uso en composiciones farmacéuticas. - Google Patents

Nuevos complejos metálicos de nocardamina y su uso en composiciones farmacéuticas.

Info

Publication number
MX385304B
MX385304B MX2017008234A MX2017008234A MX385304B MX 385304 B MX385304 B MX 385304B MX 2017008234 A MX2017008234 A MX 2017008234A MX 2017008234 A MX2017008234 A MX 2017008234A MX 385304 B MX385304 B MX 385304B
Authority
MX
Mexico
Prior art keywords
complexes
nocardamine
pharmaceutical compositions
sup
metal complexes
Prior art date
Application number
MX2017008234A
Other languages
English (en)
Other versions
MX2017008234A (es
Inventor
Eduard Berenshtein
Mordechai Chevion
Ron Eliashar
Vladimir Vinokur
Original Assignee
Mordechai Chevion
Eduard Berenshtein
Ron Eliashar
Vladimir Vinokur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mordechai Chevion, Eduard Berenshtein, Ron Eliashar, Vladimir Vinokur filed Critical Mordechai Chevion
Publication of MX2017008234A publication Critical patent/MX2017008234A/es
Publication of MX385304B publication Critical patent/MX385304B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D259/00—Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención se refiere a complejos de nocardamina (desferrioxamina E) con al menos un metal, específicamente con Zn24 o Ga3* o plata u oro, o cualquier combinación de los mismos. La invención proporciona además procedimientos para la preparación de los complejos y composiciones farmacéuticas que comprenden dichos complejos o cualquier combinación de dichos complejos, además de métodos que usan las composiciones y complejos de la invención en modular los niveles de citocinas en un sujeto y así tratar trastornos asociados a la inflamación.
MX2017008234A 2014-12-22 2015-12-22 Nuevos complejos metálicos de nocardamina y su uso en composiciones farmacéuticas. MX385304B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462095212P 2014-12-22 2014-12-22
PCT/IL2015/051243 WO2016103260A1 (en) 2014-12-22 2015-12-22 New metal complexes of nocardamine and their use in pharmaceutical compositions

Publications (2)

Publication Number Publication Date
MX2017008234A MX2017008234A (es) 2018-02-23
MX385304B true MX385304B (es) 2025-03-14

Family

ID=55221469

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017008234A MX385304B (es) 2014-12-22 2015-12-22 Nuevos complejos metálicos de nocardamina y su uso en composiciones farmacéuticas.

Country Status (12)

Country Link
US (2) US20190022103A1 (es)
EP (1) EP3236970B1 (es)
JP (2) JP6609320B2 (es)
KR (1) KR102417080B1 (es)
CN (1) CN107206091A (es)
AU (1) AU2015369552B2 (es)
CA (1) CA2971824A1 (es)
DK (1) DK3236970T3 (es)
IL (1) IL252739B (es)
MX (1) MX385304B (es)
SG (1) SG11201704815VA (es)
WO (1) WO2016103260A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015369552B2 (en) * 2014-12-22 2020-11-19 Eduard Berenshtein New metal complexes of nocardamine and their use in pharmaceutical compositions
WO2017096013A1 (en) 2015-12-01 2017-06-08 Cornell University Use of mitochondrial iron chelators for treatment of chronic obstructive pulmonary disease
CN113646634A (zh) 2019-03-29 2021-11-12 豪夫迈·罗氏有限公司 过渡金属螯合珠粒
JP7734973B2 (ja) * 2020-04-14 2025-09-08 ヴェクター ヴィターレ アイピー エルエルシー ウイルス感染を予防または処置する方法
JP7578943B2 (ja) * 2020-07-13 2024-11-07 学校法人自治医科大学 褥瘡治療剤
CN114452285B (zh) * 2022-02-17 2022-11-25 中国中医科学院中药研究所 一种il-17a拮抗剂在治疗糖尿病溃疡中的用途
KR20260015873A (ko) * 2023-05-22 2026-02-03 블라디미르 비노쿠르 염증 관련 장애 치료를 위한 신규 조성물

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3471476A (en) * 1964-05-18 1969-10-07 Tino Gaeumann Trihydroxamic acids
EP0325559B1 (de) * 1988-01-20 1993-12-15 Ciba-Geigy Ag Verfahren zur Herstellung von Komplexverbindungen
IL91047A (en) 1989-07-19 1993-06-10 Yissum Res Dev Co Zinc complexes for the treatment of free radical- induced diseases
US5618838A (en) 1993-06-18 1997-04-08 Yissum Research Development Company Of The Hebrew University Of Jerusalem Gallium complexes for the treatment of free radical-induced diseases
IL106064A (en) * 1993-06-18 1997-11-20 Yissum Res Dev Co Gallium complexes for the treatment of free radical-induced diseases
US5493053A (en) * 1994-12-21 1996-02-20 University Of Florida Research Foundation, Inc. Method for preparing desferrioxamine B and homologs thereof
AU2003290393A1 (en) * 2003-01-07 2004-07-29 Hadasit Medical Research Services & Development Ltd. Composition comprising a desferrioxamine-metal complex and its use for treating tissue damage following exposure to warfare agent
US8680148B2 (en) * 2006-08-11 2014-03-25 University Of Washington Metallo-desferrioxamine complexes and their use in the treatment of bacterial infections
DE102007008655A1 (de) 2007-02-20 2008-08-21 Henkel Ag & Co. Kgaa Siderophor-Metall-Komplexe als Bleichkatalysatoren
JP4630942B2 (ja) * 2008-01-25 2011-02-09 シャープ株式会社 移動局装置、データ送信方法及びプログラム
BR112012003447A2 (pt) * 2009-08-19 2018-03-20 Hadasit Med Res Service método de prevenir, tratar, melhorar ou inibir uma desordem relacionada ao sistema imunológico, uso de uma quantidade terapeuticamente eficaz de pelo menos um complexo de metal desferrioxamina (complexo de metal-dfo), composição e composição farmacêutica.
DE102010028742A1 (de) * 2010-05-07 2011-11-10 Henkel Ag & Co. Kgaa Waschhilfsmittel mit bleichkatalysierenden Metallkomplexen
AU2013309496A1 (en) * 2012-08-28 2014-06-05 Original BioMedicals Co., Ltd The controlled release method for a pharmaceutical composition composed of chelating complex micelles
AU2015369552B2 (en) * 2014-12-22 2020-11-19 Eduard Berenshtein New metal complexes of nocardamine and their use in pharmaceutical compositions

Also Published As

Publication number Publication date
EP3236970A1 (en) 2017-11-01
JP6609320B2 (ja) 2019-11-20
IL252739B (en) 2021-03-25
JP2020023558A (ja) 2020-02-13
JP2018501312A (ja) 2018-01-18
AU2015369552B2 (en) 2020-11-19
MX2017008234A (es) 2018-02-23
CN107206091A (zh) 2017-09-26
DK3236970T3 (da) 2021-01-18
KR20170096194A (ko) 2017-08-23
IL252739A0 (en) 2017-08-31
EP3236970B1 (en) 2020-12-16
AU2015369552A1 (en) 2017-07-27
SG11201704815VA (en) 2017-07-28
KR102417080B1 (ko) 2022-07-05
WO2016103260A1 (en) 2016-06-30
US20190022103A1 (en) 2019-01-24
US20230181597A1 (en) 2023-06-15
CA2971824A1 (en) 2016-06-30

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