MX2019006510A - Sistema y metodos para el biocontrol de patogenos en plantas. - Google Patents

Sistema y metodos para el biocontrol de patogenos en plantas.

Info

Publication number
MX2019006510A
MX2019006510A MX2019006510A MX2019006510A MX2019006510A MX 2019006510 A MX2019006510 A MX 2019006510A MX 2019006510 A MX2019006510 A MX 2019006510A MX 2019006510 A MX2019006510 A MX 2019006510A MX 2019006510 A MX2019006510 A MX 2019006510A
Authority
MX
Mexico
Prior art keywords
methods
novel
pathogen
deliver
preferred
Prior art date
Application number
MX2019006510A
Other languages
English (en)
Inventor
Richard Sayre
Karen Yin
Nunes Pedro Costa
Original Assignee
Pebble Labs Usa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pebble Labs Usa Inc filed Critical Pebble Labs Usa Inc
Publication of MX2019006510A publication Critical patent/MX2019006510A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H17/00—Symbiotic or parasitic combinations including one or more new plants, e.g. mycorrhiza
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H3/00—Processes for modifying phenotypes, e.g. symbiosis with bacteria
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/60—Isolated nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111—General methods applicable to biologically active non-coding nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8283—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for virus resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/53—Physical structure partially self-complementary or closed
    • C12N2310/531—Stem-loop; Hairpin

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La tecnología inventiva se relaciona con nuevos sistemas, métodos y estrategias para el control de los patógenos de las plantas y los herbívoros. La tecnología inventiva puede incluir específicamente nuevas composiciones, sistemas y métodos configurados para administrar moléculas de ARN inhibidoras a una planta infectada por patógenos. En una realización preferente, la invención puede incluir bacterias endofíticas modificadas por ingeniería genética configurada para entregar una o más moléculas de ARN inhibitorias a una planta infectada por patógenos. Una realización preferente puede incluir un nuevo suministro de trans-reino de ARN en una horquilla que se dirige a las proteínas codificadas por virus, lo que resulta en la reducción de los niveles de acumulación de proteínas virales.
MX2019006510A 2016-12-06 2017-12-06 Sistema y metodos para el biocontrol de patogenos en plantas. MX2019006510A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662430671P 2016-12-06 2016-12-06
PCT/US2017/064977 WO2018106847A1 (en) 2016-12-06 2017-12-06 System and methods for the biocontrol of plant pathogens

Publications (1)

Publication Number Publication Date
MX2019006510A true MX2019006510A (es) 2020-08-03

Family

ID=62491339

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019006510A MX2019006510A (es) 2016-12-06 2017-12-06 Sistema y metodos para el biocontrol de patogenos en plantas.

Country Status (11)

Country Link
US (1) US20200071713A1 (es)
EP (1) EP3550960A4 (es)
JP (1) JP2020511472A (es)
KR (1) KR20190122647A (es)
CN (1) CN110402085A (es)
AU (1) AU2017370683A1 (es)
BR (1) BR112019011642A2 (es)
CA (1) CA3046081A1 (es)
IL (1) IL267133A (es)
MX (1) MX2019006510A (es)
WO (1) WO2018106847A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3755801A4 (en) * 2018-02-22 2022-02-23 Dow AgroSciences LLC SHORT/SMALL HAIRPIN RNA MOLECULES
CA3109956A1 (en) * 2018-08-24 2020-02-27 Flagship Pioneering Innovations Vi, Llc Methods and compositions for the modification of plants
CN109266580B (zh) * 2018-09-29 2022-06-14 新疆师范大学 一种共生抗干旱促种子萌发内生菌及其应用
CN109511587B (zh) * 2018-11-01 2021-03-30 浙江海洋大学 用于网箱孵化麦穗鱼的消毒剂
CN110241114B (zh) * 2019-03-20 2023-09-22 中国热带农业科学院热带生物技术研究所 一种可防控蚊虫的双链rna及其应用
CN110042115A (zh) * 2019-04-30 2019-07-23 贵州大学 一种马铃薯长管蚜效应蛋白Me23基因的重组载体和表达方法
CN110592101B (zh) * 2019-10-18 2020-09-25 河南大学 油菜转录因子BnWRKY184、克隆方法、载体、宿主细胞及应用
WO2021173953A1 (en) * 2020-02-26 2021-09-02 Pebble Labs, Inc. Novel plant endophytic bacteria and methods to control plant pathogens and pests
CN111771911B (zh) * 2020-06-30 2021-06-04 武汉合缘绿色生物股份有限公司 一种防治烟草花叶病毒的微生物制剂及其制备方法
CN112063623B (zh) * 2020-09-10 2022-03-25 南京农业大学 一种抑制水稻纹枯病菌的dsRNA及其应用
CN112458087B (zh) * 2020-11-06 2021-06-08 华南师范大学 基于美洲大蠊HDAC1基因设计的dsRNA、其制备方法、编码基因及其应用
WO2022117658A1 (en) * 2020-12-01 2022-06-09 Redbiotec Ag Bacterial delivery of gene silencing tools into eukaryotic cells
CN112940994B (zh) * 2021-04-25 2022-08-23 金禾佳农（北京）生物技术有限公司 一种枯草芽孢杆菌、培养方法及应用
CN113151281A (zh) * 2021-05-30 2021-07-23 中国农业大学 靶向沉默辣椒疫霉纤维素合酶3的植物表达载体及其应用
WO2023023285A2 (en) * 2021-08-19 2023-02-23 Twist Bioscience Corporation Methods and compositions relating to covalently closed nucleic acids
CN114292316B (zh) * 2021-12-22 2023-03-24 西北农林科技大学 一种小麦条锈菌分泌蛋白、鉴定方法、转基因植株及应用
CN114806895B (zh) * 2022-05-20 2023-02-28 浙江大学 内生真菌m-b927在提高水稻谷粒产量中的应用
CN115058449B (zh) * 2022-06-24 2023-05-16 西南大学 一种利用CsWRKY43干扰以提高柑橘溃疡病抗性的方法
CN116064586B (zh) * 2022-11-01 2024-04-02 广东省农业科学院果树研究所 一种番木瓜CpWRKY50基因及其提高番木瓜炭疽病抗性的用途
CN118063578A (zh) * 2024-03-15 2024-05-24 中国热带农业科学院南亚热带作物研究所 菠萝Ca2+/H+反向转运蛋白AcCAX1、基因及其应用
CN118063577A (zh) * 2024-03-15 2024-05-24 中国热带农业科学院南亚热带作物研究所 菠萝Ca2+/H+反向转运蛋白AcCAX3、分离的核酸分子及其应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005110068A2 (en) * 2004-04-09 2005-11-24 Monsanto Technology Llc Compositions and methods for control of insect infestations in plants
JP4249727B2 (ja) * 2005-05-13 2009-04-08 株式会社東芝 非水電解質電池およびリチウムチタン複合酸化物
EP2275562B1 (en) * 2005-09-16 2015-10-21 deVGen N.V. Transgenic plant-based methods for plant insect pests using RNAi
PL2270182T3 (pl) * 2005-09-16 2016-07-29 Devgen Nv dsRNA jako środek do kontroli owadów
WO2007067476A2 (en) * 2005-12-05 2007-06-14 Merck & Co., Inc. Methods for predicting treatment response based on the expression profiles of protein and transcription biomakers
EP1971688B1 (en) * 2006-01-12 2012-03-14 Devgen NV Dsrna as insect control agent
EP1984511A2 (en) * 2006-02-13 2008-10-29 Monsanto Technology LLP Selecting and stabilizing dsrna constructs
US9051565B2 (en) * 2007-05-22 2015-06-09 Cornell Research Foundation, Inc. Compositions and methods for the display of proteins on the surface of bacteria and their derived vesicles and uses thereof
CN107267514A (zh) * 2008-04-10 2017-10-20 孟山都技术公司 用于根结线虫防治的方法和组合物
GB201009601D0 (en) * 2010-06-08 2010-07-21 Devgen Private Ltd Method for down-grading gene expression in fungi
MX370669B (es) * 2012-06-22 2019-12-19 Syngenta Participations Ag Control biológico de plagas de coleópteros.
BR122023020863A2 (pt) * 2014-09-17 2024-01-30 Spogen Biotech Inc Método para estimular o crescimento de plantas
US10550400B2 (en) * 2014-12-15 2020-02-04 Paris Sciences Et Lettres—Quartier Latin Methods to monitor post-translational gene silencing activity in plant tissues/cell types relevant for pathogen entry, propagation or replication
MX2017007904A (es) * 2014-12-23 2017-09-05 Syngenta Participations Ag Control biologico de plagas de coleopteros.

Also Published As

Publication number Publication date
IL267133A (en) 2019-08-29
KR20190122647A (ko) 2019-10-30
WO2018106847A1 (en) 2018-06-14
AU2017370683A1 (en) 2019-06-27
JP2020511472A (ja) 2020-04-16
EP3550960A4 (en) 2020-08-12
CA3046081A1 (en) 2018-06-14
BR112019011642A2 (pt) 2019-10-22
CN110402085A (zh) 2019-11-01
US20200071713A1 (en) 2020-03-05
EP3550960A1 (en) 2019-10-16

Similar Documents

Publication Publication Date Title
MX2019006510A (es) Sistema y metodos para el biocontrol de patogenos en plantas.
EP4253551A3 (en) Novel crispr dna and rna targeting enzymes and systems
MX2020011939A (es) Nuevas enzimas y sistemas crispr.
AU2018251801A8 (en) Novel type VI CRISPR orthologs and systems
WO2019006471A3 (en) NOVEL CRISPR RNA TARGETING ENZYMES, SYSTEMS AND USES THEREOF
PL3765615T3 (pl) Nowe enzymy i układy crispr ukierunkowane na dna
PH12017500614A1 (en) Compositions and methods for silencing hepatitis b virus gene expression
WO2016154127A3 (en) Compositions and methods for treating hypertriglyceridemia
NZ724277A (en) Compositions and methods for modulating pkk expression
PH12017550069A1 (en) Tau antisense oligomers and uses thereof
WO2017019891A3 (en) Compositions and methods for silencing hepatitis b virus gene expression
NZ733882A (en) Compositions for modulating c9orf72 expression
WO2016183366A3 (en) Compositions and methods for silencing expression of hepatitis d virus rna
PH12019500209A1 (en) Methods and compositions for gene expression in plants
ZA202202628B (en) Novel crispr dna targeting enzymes and systems
MX2024002327A (es) Sistemas y metodos para direccion con arn guia puntual (arngp) de adn endogeno y fuente.
MX2017017079A (es) Sistema de administracion dirigida de principio activo celular.
WO2016046234A3 (en) Recombinant phe-free proteins for use in the treatment of phenylketonuria
MX2020008272A (es) Nucleasas diseñadas específicas de blancos.
MX2018010288A (es) Sistema de transposon y metodos de uso.
PH12019500583A1 (en) Novel paratransgenic system for the biocontrol of disease-transmitting mosquitos
AU2017260426A1 (en) Engineered nucleases useful for treatment of hemophilia A
EP3277743A4 (en) HYPERBRANCHED POLYMERS AND POLYPLEXES AND DNA OR RNA DELIVERY SYSTEMS THEREWITH
MX2024005259A (es) Adenovirus y metodos para usar adenovirus.
AU2018280528A8 (en) Method for improving transformation efficiency of plant and method for transforming plant