MX2018008778A - Metodos y sistemas de deteccion rapida de microorganismos utilizando agentes infecciosos. - Google Patents

Metodos y sistemas de deteccion rapida de microorganismos utilizando agentes infecciosos.

Info

Publication number
MX2018008778A
MX2018008778A MX2018008778A MX2018008778A MX2018008778A MX 2018008778 A MX2018008778 A MX 2018008778A MX 2018008778 A MX2018008778 A MX 2018008778A MX 2018008778 A MX2018008778 A MX 2018008778A MX 2018008778 A MX2018008778 A MX 2018008778A
Authority
MX
Mexico
Prior art keywords
microorganisms
systems
methods
rapid detection
infectious agents
Prior art date
Application number
MX2018008778A
Other languages
English (en)
Inventor
Lyman Anderson Dwight
Barrett Hopkins Ben
S Gil Jose
ERICKSON Stephen
Mindy Bao Nguyen Minh
Original Assignee
Laboratory Corp America Holdings
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US15/263,619 external-priority patent/US20170131275A1/en
Application filed by Laboratory Corp America Holdings filed Critical Laboratory Corp America Holdings
Publication of MX2018008778A publication Critical patent/MX2018008778A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/73—Expression systems using phage (lambda) regulatory sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/10—Enterobacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

En la presente se describen métodos y sistemas para la detección rápida de microorganismos en una muestra. También se describe un bacteriófago genéticamente modificado que comprende un gen indicador en la región del gen tardío. La especificidad del bacteriófago, tal como CBA120, permite la detección de un microorganismo específico, tal como E. coli O157:H7, y se puede amplificar una señal indicadora para optimizar la sensibilidad del ensayo.
MX2018008778A 2016-01-18 2017-01-18 Metodos y sistemas de deteccion rapida de microorganismos utilizando agentes infecciosos. MX2018008778A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662280043P 2016-01-18 2016-01-18
US201662280465P 2016-01-19 2016-01-19
US15/263,619 US20170131275A1 (en) 2012-02-21 2016-09-13 Methods and systems for detection of microorganisms
PCT/US2017/013955 WO2017127434A1 (en) 2016-01-18 2017-01-18 Methods and systems for rapid detection of microorganisms using infectious agents

Publications (1)

Publication Number Publication Date
MX2018008778A true MX2018008778A (es) 2018-09-12

Family

ID=59362121

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018008778A MX2018008778A (es) 2016-01-18 2017-01-18 Metodos y sistemas de deteccion rapida de microorganismos utilizando agentes infecciosos.

Country Status (8)

Country Link
EP (1) EP3405590A1 (es)
JP (2) JP2019509020A (es)
CN (2) CN108884498A (es)
AU (1) AU2017209041B2 (es)
BR (1) BR112018014166A2 (es)
CA (1) CA3011704A1 (es)
MX (1) MX2018008778A (es)
WO (1) WO2017127434A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10519483B2 (en) 2012-02-21 2019-12-31 Laboratory Corporation Of America Holdings Methods and systems for rapid detection of microorganisms using infectious agents
EP3737746A1 (en) 2018-01-12 2020-11-18 Laboratory Corporation of America Holdings Methods and systems for the rapid detection of salmonella using infectious agents
CN112313337A (zh) * 2018-04-24 2021-02-02 美国控股实验室公司 选择和监测治疗功效的指示物噬菌体及其使用方法
BR112021013769A2 (pt) * 2019-01-29 2021-09-21 Laboratory Corporation Of America Holdings Métodos e sistemas para a detecção rápida de listeria usando agentes infecciosos.
EP3987015A1 (en) * 2019-06-21 2022-04-27 Laboratory Corporation of America Holdings Methods for producing mutant bacteriophages for the detection of listeria
CN114729332A (zh) 2019-08-26 2022-07-08 美国控股实验室公司 用于使用重组繁殖缺陷性指示噬菌体检测微生物的装置和方法
MX2022003092A (es) 2019-09-11 2022-06-08 Laboratory Corp America Holdings Metodos y sistemas para la deteccion rapida de microorganismos utilizando agentes infecciosos recombinantes para expresar una subunidad indicadora.
WO2022094393A1 (en) * 2020-10-30 2022-05-05 Albert Einstein College Of Medicine Reporter mycobacteriophage, assays and methods comprising the reporter mycobacteriophage
EP4252005A1 (en) * 2020-11-25 2023-10-04 Laboratory Corporation of America Holdings Methods and systems for the detection of microorganisms using infectious agents

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19517940A1 (de) * 1995-05-18 1996-11-21 Merck Patent Gmbh Nachweis von Listerien mittels rekombinanter Bakteriophagen
AU2002361548A1 (en) * 2001-07-13 2003-05-06 Investigen, Inc. Compositions and methods for bacteria detection
JP4235718B2 (ja) * 2003-03-07 2009-03-11 株式会社荏原製作所 大腸菌の検出方法及び大腸菌検出用ファージ
CN1298840C (zh) * 2003-09-24 2007-02-07 冯书章 肠出血性大肠杆菌o157基因缺失疫苗
MX2007014837A (es) * 2005-05-26 2008-02-21 Gangagen Life Sciences Inc Administracion bacterial en sistemas de retencion de animales.
EP2142667B1 (en) * 2007-04-05 2014-12-03 Sequella, Inc. Improved methods and compositions for determining the pathogenic status of infectious agents
WO2008131230A1 (en) * 2007-04-18 2008-10-30 Cornell University Microorganism detection method and apparatus
US8114622B2 (en) * 2008-08-29 2012-02-14 Purdue Research Foundation Methods for generation of reporter phages and immobilization of active bacteriophages on a polymer surface
WO2013126584A1 (en) * 2012-02-21 2013-08-29 Laboratory Corporation Of America Holdings Methods and systems for detection of microorganisms
US10519483B2 (en) * 2012-02-21 2019-12-31 Laboratory Corporation Of America Holdings Methods and systems for rapid detection of microorganisms using infectious agents
KR101299179B1 (ko) * 2012-04-18 2013-08-22 씨제이제일제당 (주) 신규 박테리오파지 및 이를 포함하는 항균 조성물
JP6300222B2 (ja) * 2013-09-25 2018-03-28 国立大学法人東京工業大学 遺伝子組換えウイルスによる微生物の迅速検出法
EP3108014B1 (en) * 2014-02-18 2018-12-05 Laboratory Corporation of America Holdings Methods and systems for rapid detection of microorganisms using recombinant bacteriophage
CA2947441A1 (en) * 2014-05-09 2015-11-12 Sample6 Technologies, Inc. Codon-optimized recombinant phage and methods of using same

Also Published As

Publication number Publication date
WO2017127434A1 (en) 2017-07-27
AU2017209041A1 (en) 2018-07-26
BR112018014166A2 (pt) 2018-12-26
AU2017209041B2 (en) 2023-03-30
JP2022024167A (ja) 2022-02-08
JP2019509020A (ja) 2019-04-04
CN108884498A (zh) 2018-11-23
CN115960844A (zh) 2023-04-14
EP3405590A1 (en) 2018-11-28
CA3011704A1 (en) 2017-07-27

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