MX2016013241A - Animales no humanos que tienen receptores fc gamma humanizados. - Google Patents

Animales no humanos que tienen receptores fc gamma humanizados.

Info

Publication number
MX2016013241A
MX2016013241A MX2016013241A MX2016013241A MX2016013241A MX 2016013241 A MX2016013241 A MX 2016013241A MX 2016013241 A MX2016013241 A MX 2016013241A MX 2016013241 A MX2016013241 A MX 2016013241A MX 2016013241 A MX2016013241 A MX 2016013241A
Authority
MX
Mexico
Prior art keywords
humanized
human animals
gamma receptors
receptors
gamma
Prior art date
Application number
MX2016013241A
Other languages
English (en)
Inventor
J Murphy Andrew
Macdonald Lynn
Tu Naxin
A Meagher Karolina
Curer Cagan
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of MX2016013241A publication Critical patent/MX2016013241A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/15—Humanized animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/072—Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0337—Animal models for infectious diseases
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/035—Animal model for multifactorial diseases
    • A01K2267/0387—Animal model for diseases of the immune system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Electric Clocks (AREA)

Abstract

Se proporcionan ratones modificados genéticamente y métodos y composiciones para generarlos y usarlos, en donde la modificación genética comprende la humanización de una proteína FcyRl.
MX2016013241A 2014-04-08 2015-04-08 Animales no humanos que tienen receptores fc gamma humanizados. MX2016013241A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461977037P 2014-04-08 2014-04-08
PCT/US2015/024920 WO2015157415A1 (en) 2014-04-08 2015-04-08 Non-human animals having humanized fc-gamma receptors

Publications (1)

Publication Number Publication Date
MX2016013241A true MX2016013241A (es) 2017-05-03

Family

ID=52997579

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016013241A MX2016013241A (es) 2014-04-08 2015-04-08 Animales no humanos que tienen receptores fc gamma humanizados.

Country Status (24)

Country Link
US (4) US9474255B2 (es)
EP (2) EP3693383A1 (es)
JP (2) JP6652931B2 (es)
KR (2) KR102439412B1 (es)
CN (2) CN111690052B (es)
AU (2) AU2015243865C1 (es)
CA (1) CA2935472C (es)
CY (1) CY1123046T1 (es)
DK (1) DK3129400T3 (es)
ES (1) ES2794942T3 (es)
HR (1) HRP20200899T1 (es)
HU (1) HUE051088T2 (es)
IL (2) IL246497B (es)
LT (1) LT3129400T (es)
MX (1) MX2016013241A (es)
PH (1) PH12016501341A1 (es)
PL (1) PL3129400T3 (es)
PT (1) PT3129400T (es)
RS (1) RS60398B1 (es)
RU (2) RU2700484C2 (es)
SG (2) SG10201908800YA (es)
SI (1) SI3129400T1 (es)
SM (1) SMT202000332T1 (es)
WO (1) WO2015157415A1 (es)

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HUE048677T2 (hu) 2014-06-19 2020-07-28 Regeneron Pharma Humanizált programozott sejthalál 1 génnel rendelkezõ nem-humán állatok
KR20240055876A (ko) 2014-11-24 2024-04-29 리제너론 파마슈티칼스 인코포레이티드 인간화 cd3 복합체를 발현하는 비인간 동물
KR102617691B1 (ko) 2014-12-05 2023-12-27 리제너론 파마슈티칼스 인코포레이티드 인간화 분화 클러스터 47 유전자를 가진 비인간 동물
NZ731954A (en) 2014-12-09 2024-11-29 Regeneron Pharma Non-human animals having a humanized cluster of differentiation 274 gene
AU2016358101B2 (en) 2015-11-20 2022-12-01 Regeneron Pharmaceuticals, Inc. Non-human animals having a humanized Lymphocyte-activation gene 3
JP6980674B2 (ja) 2016-02-29 2021-12-15 リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. ヒト化ｔｍｐｒｓｓ遺伝子を有する齧歯類
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Also Published As

Publication number Publication date
IL246497B (en) 2019-06-30
AU2020217312A1 (en) 2020-08-27
CN106163273A (zh) 2016-11-23
EP3693383A1 (en) 2020-08-12
KR102439412B1 (ko) 2022-09-02
EP3129400B1 (en) 2020-03-25
SI3129400T1 (sl) 2020-07-31
RS60398B1 (sr) 2020-07-31
CN106163273B (zh) 2020-07-24
CY1123046T1 (el) 2021-10-29
AU2020217312B2 (en) 2023-04-13
HRP20200899T1 (hr) 2020-09-04
CA2935472C (en) 2024-02-20
KR102223264B1 (ko) 2021-03-09
JP2020062051A (ja) 2020-04-23
SMT202000332T1 (it) 2020-07-08
PH12016501341A1 (en) 2016-08-15
CN111690052A (zh) 2020-09-22
CA2935472A1 (en) 2015-10-15
AU2020217312C1 (en) 2023-10-26
RU2700484C2 (ru) 2019-09-17
US20230232795A1 (en) 2023-07-27
JP6652931B2 (ja) 2020-02-26
KR20160142309A (ko) 2016-12-12
JP6858283B2 (ja) 2021-04-14
IL264364A (en) 2019-02-28
AU2015243865C1 (en) 2020-11-26
RU2016143036A3 (es) 2018-10-24
AU2015243865A1 (en) 2016-08-18
AU2015243865B2 (en) 2020-05-14
PL3129400T3 (pl) 2020-09-07
RU2019128394A (ru) 2019-10-07
US20150282463A1 (en) 2015-10-08
PT3129400T (pt) 2020-05-27
IL264364B (en) 2021-03-25
EP3129400A1 (en) 2017-02-15
IL246497A0 (en) 2016-08-31
HUE051088T2 (hu) 2021-03-01
JP2017510285A (ja) 2017-04-13
ES2794942T3 (es) 2020-11-19
US20200288684A1 (en) 2020-09-17
US20170086432A1 (en) 2017-03-30
CN111690052B (zh) 2024-06-04
DK3129400T3 (da) 2020-06-08
SG10201908800YA (en) 2019-11-28
WO2015157415A1 (en) 2015-10-15
US11503812B2 (en) 2022-11-22
SG11201604886WA (en) 2016-07-28
US9474255B2 (en) 2016-10-25
KR20210024249A (ko) 2021-03-04
US10555507B2 (en) 2020-02-11
RU2016143036A (ru) 2018-05-08
LT3129400T (lt) 2020-06-25

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