PT3129400T - Animais não humanos que possuem recetores fc-gamma humanizados - Google Patents

Animais não humanos que possuem recetores fc-gamma humanizados

Info

Publication number
PT3129400T
PT3129400T PT157180605T PT15718060T PT3129400T PT 3129400 T PT3129400 T PT 3129400T PT 157180605 T PT157180605 T PT 157180605T PT 15718060 T PT15718060 T PT 15718060T PT 3129400 T PT3129400 T PT 3129400T
Authority
PT
Portugal
Prior art keywords
humanized
human animals
gamma receptors
receptors
gamma
Prior art date
Application number
PT157180605T
Other languages
English (en)
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of PT3129400T publication Critical patent/PT3129400T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/027—New breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0278—Humanized animals, e.g. knockin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/15—Humanized animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/072—Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0337—Animal models for infectious diseases
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/035—Animal model for multifactorial diseases
    • A01K2267/0387—Animal model for diseases of the immune system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
PT157180605T 2014-04-08 2015-04-08 Animais não humanos que possuem recetores fc-gamma humanizados PT3129400T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461977037P 2014-04-08 2014-04-08

Publications (1)

Publication Number Publication Date
PT3129400T true PT3129400T (pt) 2020-05-27

Family

ID=52997579

Family Applications (1)

Application Number Title Priority Date Filing Date
PT157180605T PT3129400T (pt) 2014-04-08 2015-04-08 Animais não humanos que possuem recetores fc-gamma humanizados

Country Status (23)

Country Link
US (4) US9474255B2 (pt)
EP (2) EP3693383A1 (pt)
JP (2) JP6652931B2 (pt)
KR (2) KR102223264B1 (pt)
CN (2) CN111690052A (pt)
AU (2) AU2015243865C1 (pt)
CA (1) CA2935472C (pt)
CY (1) CY1123046T1 (pt)
DK (1) DK3129400T3 (pt)
ES (1) ES2794942T3 (pt)
HR (1) HRP20200899T1 (pt)
HU (1) HUE051088T2 (pt)
IL (2) IL246497B (pt)
LT (1) LT3129400T (pt)
MX (1) MX2016013241A (pt)
PH (1) PH12016501341A1 (pt)
PL (1) PL3129400T3 (pt)
PT (1) PT3129400T (pt)
RS (1) RS60398B1 (pt)
RU (2) RU2019128394A (pt)
SG (2) SG11201604886WA (pt)
SI (1) SI3129400T1 (pt)
WO (1) WO2015157415A1 (pt)

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SI3129400T1 (sl) * 2014-04-08 2020-07-31 Regeneron Pharmaceuticals, Inc. Živali, ki niso človek in imajo humanizirane receptorje FC-gama
NO2785538T3 (pt) 2014-05-07 2018-08-04
CA2951278A1 (en) 2014-06-19 2015-12-23 Regeneron Pharmaceuticals, Inc. Non-human animals having a humanized programmed cell death 1 gene
ES2923775T3 (es) 2014-11-24 2022-09-30 Regeneron Pharma Animales no humanos que expresan el complejo CD3 humanizado
JP6730277B2 (ja) 2014-12-05 2020-07-29 リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． ヒト化されたｃｌｕｓｔｅｒ ｏｆ ｄｉｆｆｅｒｅｎｔｉａｔｉｏｎ ４７遺伝子を有する非ヒト動物
JP6997708B2 (ja) 2015-11-20 2022-02-04 リジェネロン・ファーマシューティカルズ・インコーポレイテッド ヒト化されたｌｙｍｐｈｏｃｙｔｅ－ａｃｔｉｖａｔｉｏｎ ｇｅｎｅ ３遺伝子を有する非ヒト動物
KR102493894B1 (ko) 2016-02-29 2023-01-31 리제너론 파마슈티칼스 인코포레이티드 인간화 tmprss 유전자를 갖는 설치류
EP3585164B1 (en) 2017-11-30 2023-12-27 Regeneron Pharmaceuticals, Inc. Rats comprising a humanized trkb locus
TWI829679B (zh) * 2018-03-26 2024-01-21 美商再生元醫藥公司 用於測試治療藥劑之人類化囓齒動物
KR20210031868A (ko) 2018-07-16 2021-03-23 리제너론 파마슈티칼스 인코포레이티드 Ditra 질환의 비인간 동물 모델 및 이의 용도
CA3199879A1 (en) 2020-12-16 2022-06-23 Regeneron Pharmaceuticals, Inc. Mice expressing humanized fc alpha receptors

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JP5909449B2 (ja) * 2009-12-10 2016-04-26 リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 重鎖抗体を作製するマウス
KR101862277B1 (ko) 2009-12-21 2018-06-01 리제너론 파마슈티칼스 인코포레이티드 인간화된 ＦｃγＲ 마우스
DK3262932T3 (da) 2011-10-28 2019-08-05 Regeneron Pharma Genmodificerede mus med major histokompatibilitetskompleks
RS55949B1 (sr) 2011-10-28 2017-09-29 Regeneron Pharmaeuticals Inc Humanizovani il-6 i il-6 receptor
RS59997B1 (sr) 2011-10-28 2020-04-30 Regeneron Pharma Genetski modifikovani miševi sa ekspresijom himernih molekula klase ii glavnog kompleksa histokompatibilnosti (mhc)
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DK2958938T3 (da) 2013-02-20 2019-07-15 Regeneron Pharma Mus, der eksprimerer humaniserede T-celle-co-receptorer
LT2958937T (lt) 2013-02-22 2018-11-26 Regeneron Pharmaceuticals, Inc. Pelė, ekspresuojanti humanizuotą audinių dermės kompleksą
ES2959333T3 (es) 2013-09-23 2024-02-23 Regeneron Pharma Animales no humanos que tienen un gen humanizado de la proteína reguladora de señales
MX356809B (es) 2013-11-19 2018-06-13 Regeneron Pharma Animales no humanos que tienen un gen del factor activador de celulas b.
EP3071025B1 (en) 2013-11-19 2018-10-10 Regeneron Pharmaceuticals, Inc. Non-human animals having a humanized a proliferation-inducing ligand gene
SI3129400T1 (sl) * 2014-04-08 2020-07-31 Regeneron Pharmaceuticals, Inc. Živali, ki niso človek in imajo humanizirane receptorje FC-gama

Also Published As

Publication number Publication date
JP6858283B2 (ja) 2021-04-14
EP3693383A1 (en) 2020-08-12
US9474255B2 (en) 2016-10-25
KR20210024249A (ko) 2021-03-04
KR20160142309A (ko) 2016-12-12
RU2016143036A3 (pt) 2018-10-24
AU2015243865A1 (en) 2016-08-18
IL246497A0 (en) 2016-08-31
US20150282463A1 (en) 2015-10-08
RU2019128394A (ru) 2019-10-07
EP3129400A1 (en) 2017-02-15
AU2020217312A1 (en) 2020-08-27
US11503812B2 (en) 2022-11-22
US10555507B2 (en) 2020-02-11
RU2016143036A (ru) 2018-05-08
US20230232795A1 (en) 2023-07-27
MX2016013241A (es) 2017-05-03
EP3129400B1 (en) 2020-03-25
KR102439412B1 (ko) 2022-09-02
HUE051088T2 (hu) 2021-03-01
IL264364B (en) 2021-03-25
AU2020217312C1 (en) 2023-10-26
AU2015243865C1 (en) 2020-11-26
IL264364A (en) 2019-02-28
AU2015243865B2 (en) 2020-05-14
CN106163273A (zh) 2016-11-23
JP2017510285A (ja) 2017-04-13
IL246497B (en) 2019-06-30
KR102223264B1 (ko) 2021-03-09
JP6652931B2 (ja) 2020-02-26
WO2015157415A1 (en) 2015-10-15
PL3129400T3 (pl) 2020-09-07
RU2700484C2 (ru) 2019-09-17
LT3129400T (lt) 2020-06-25
SG10201908800YA (en) 2019-11-28
JP2020062051A (ja) 2020-04-23
ES2794942T3 (es) 2020-11-19
PH12016501341A1 (en) 2016-08-15
CA2935472A1 (en) 2015-10-15
CY1123046T1 (el) 2021-10-29
US20170086432A1 (en) 2017-03-30
HRP20200899T1 (hr) 2020-09-04
SI3129400T1 (sl) 2020-07-31
SG11201604886WA (en) 2016-07-28
CN111690052A (zh) 2020-09-22
CA2935472C (en) 2024-02-20
AU2020217312B2 (en) 2023-04-13
RS60398B1 (sr) 2020-07-31
DK3129400T3 (da) 2020-06-08
US20200288684A1 (en) 2020-09-17
CN106163273B (zh) 2020-07-24

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