MX2016007285A - Combinaciones de inhibidores de la captacion de serotonina-norepinefrina (irsn) y ligandos de receptores sigma. - Google Patents

Combinaciones de inhibidores de la captacion de serotonina-norepinefrina (irsn) y ligandos de receptores sigma.

Info

Publication number
MX2016007285A
MX2016007285A MX2016007285A MX2016007285A MX2016007285A MX 2016007285 A MX2016007285 A MX 2016007285A MX 2016007285 A MX2016007285 A MX 2016007285A MX 2016007285 A MX2016007285 A MX 2016007285A MX 2016007285 A MX2016007285 A MX 2016007285A
Authority
MX
Mexico
Prior art keywords
serotonin
snris
norepinephrine reuptake
receptor ligands
reuptake inhibitors
Prior art date
Application number
MX2016007285A
Other languages
English (en)
Inventor
Zamanillo-Castanedo Daniel
Portillo-Salido Enrique
Original Assignee
Esteve Labor Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Labor Dr filed Critical Esteve Labor Dr
Publication of MX2016007285A publication Critical patent/MX2016007285A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La invención se refiere a una combinación sinérgica que comprende un ligando sigma de fórmula general (I) y un inhibidor de la recaptación de serotonina-norepinefrina (IRSN), a un medicamento que comprende dicha combinación de sustancias activas y al uso de dicha combinación de sustancias activas para la fabricación de un medicamento, particularmente para la profilaxis y/o el tratamiento del dolor.
MX2016007285A 2013-12-17 2014-12-16 Combinaciones de inhibidores de la captacion de serotonina-norepinefrina (irsn) y ligandos de receptores sigma. MX2016007285A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13382518 2013-12-17
PCT/EP2014/077996 WO2015091508A1 (en) 2013-12-17 2014-12-16 SEROTONIN-NOREPINEPHRINE REUPTAKE INHIBITORS (SNRIs) AND SIGMA RECEPTOR LIGANDS COMBINATIONS

Publications (1)

Publication Number Publication Date
MX2016007285A true MX2016007285A (es) 2016-08-04

Family

ID=49885115

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016007285A MX2016007285A (es) 2013-12-17 2014-12-16 Combinaciones de inhibidores de la captacion de serotonina-norepinefrina (irsn) y ligandos de receptores sigma.

Country Status (17)

Country Link
US (1) US9931346B2 (es)
EP (1) EP3082782A1 (es)
JP (1) JP2016540771A (es)
KR (1) KR20160097366A (es)
CN (1) CN105873578A (es)
AR (1) AR101638A1 (es)
AU (1) AU2014364647A1 (es)
BR (1) BR112016013754A2 (es)
CA (1) CA2933511A1 (es)
IL (1) IL245953A0 (es)
MA (1) MA39147B1 (es)
MX (1) MX2016007285A (es)
PH (1) PH12016501096A1 (es)
SG (1) SG11201604480PA (es)
TN (1) TN2016000228A1 (es)
TW (1) TW201607538A (es)
WO (1) WO2015091508A1 (es)

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AU2014364647A1 (en) 2013-12-17 2016-06-23 Laboratorios Del Dr. Esteve, S.A. Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) and Sigma receptor ligands combinations
US11034669B2 (en) 2018-11-30 2021-06-15 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof

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CA2933511A1 (en) 2015-06-25
EP3082782A1 (en) 2016-10-26
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KR20160097366A (ko) 2016-08-17
JP2016540771A (ja) 2016-12-28
US9931346B2 (en) 2018-04-03
TN2016000228A1 (en) 2017-10-06
AR101638A1 (es) 2017-01-04
BR112016013754A2 (pt) 2017-08-08
AU2014364647A1 (en) 2016-06-23
IL245953A0 (en) 2016-07-31
US20160310500A1 (en) 2016-10-27
MA39147B1 (fr) 2019-12-31
WO2015091508A1 (en) 2015-06-25
TW201607538A (zh) 2016-03-01
PH12016501096A1 (en) 2016-07-11

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