BR0011236A - Amino heterociclos úteis como agentes farmacêuticos - Google Patents

Amino heterociclos úteis como agentes farmacêuticos

Info

Publication number
BR0011236A
BR0011236A BR0011236-4A BR0011236A BR0011236A BR 0011236 A BR0011236 A BR 0011236A BR 0011236 A BR0011236 A BR 0011236A BR 0011236 A BR0011236 A BR 0011236A
Authority
BR
Brazil
Prior art keywords
disorders
pharmaceutical agents
amino heterocycles
heterocycles useful
useful
Prior art date
Application number
BR0011236-4A
Other languages
English (en)
Inventor
Thomas Richard Belliotti
Andrew John Thorpe
David Juergen Wustrow
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of BR0011236A publication Critical patent/BR0011236A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

Patente de Invenção: "AMINO HETEROCICLOS úTEIS COMO AGENTES FARMACêUTICOS". A presente invenção é uma nova série de amino heterociclos úteis no tratamento da epilepsia, ataques de fraqueza, hipoquinesia, distúrbios cranianos, distúrbios neurodegenerativos, depressão, ansiedade, pânico, dores, distúrbios neuropatológicos e distúrbios do sono. Também são divulgados processos para a preparação e intermediários úteis na preparação.
BR0011236-4A 1999-06-02 2000-04-28 Amino heterociclos úteis como agentes farmacêuticos BR0011236A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13709699P 1999-06-02 1999-06-02
PCT/US2000/011399 WO2000073300A1 (en) 1999-06-02 2000-04-28 Amino heterocycles useful as pharmaceutical agents

Publications (1)

Publication Number Publication Date
BR0011236A true BR0011236A (pt) 2002-03-05

Family

ID=22475823

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0011236-4A BR0011236A (pt) 1999-06-02 2000-04-28 Amino heterociclos úteis como agentes farmacêuticos

Country Status (12)

Country Link
US (1) US6436974B1 (pt)
EP (1) EP1187832B1 (pt)
JP (1) JP2003525207A (pt)
AT (1) ATE228128T1 (pt)
AU (1) AU4673300A (pt)
BR (1) BR0011236A (pt)
CA (1) CA2371395A1 (pt)
DE (1) DE60000833T2 (pt)
DK (1) DK1187832T3 (pt)
ES (1) ES2185591T3 (pt)
PT (1) PT1187832E (pt)
WO (1) WO2000073300A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1094757C (zh) 1996-07-24 2002-11-27 沃尼尔·朗伯公司 用于治疗疼痛的异丁基γ－氨基丁酸及其衍生物
WO2002000209A2 (en) * 2000-06-26 2002-01-03 Warner-Lambert Company Gabapentin analogues for sleep disorders
US6855735B2 (en) * 2002-03-20 2005-02-15 Temple University Of The Commonwealth System Of Higher Education Ketamine treatment of restless legs syndrome
US20050209319A1 (en) * 2004-03-18 2005-09-22 Xenoport, Inc. Treatment of local pain
US7384929B2 (en) 2004-09-20 2008-06-10 Targacept, Inc. N-aryl azaspiroalkene and azaspiroalkane compounds and methods of preparation and use thereof
GB0514686D0 (en) * 2005-07-18 2005-08-24 Novartis Ag Organic compounds
EP1820502A1 (en) 2006-02-10 2007-08-22 Laboratorios Del Dr. Esteve, S.A. Active substance combination comprising azolylcarbinol compounds
EP2116539A1 (en) 2008-04-25 2009-11-11 Laboratorios Del. Dr. Esteve, S.A. 1-aryl-3-aminoalkoxy-pyrazoles as sigma ligands enhancing analgesic effects of opioids and attenuating the dependency thereof
EP2116618A1 (en) 2008-05-09 2009-11-11 Agency for Science, Technology And Research Diagnosis and treatment of Kawasaki disease
EP2353591A1 (en) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for potentiating the analgesic effect of opioids and opiates in post-operative pain and attenuating the dependency thereof
EP2353598A1 (en) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for use in the prevention and/or treatment of postoperative pain
EP2388005A1 (en) 2010-05-21 2011-11-23 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy
EP2415471A1 (en) 2010-08-03 2012-02-08 Laboratorios Del. Dr. Esteve, S.A. Use of sigma ligands in opioid-induced hyperalgesia
EP2524694A1 (en) 2011-05-19 2012-11-21 Laboratorios Del. Dr. Esteve, S.A. Use of sigma ligands in diabetes type-2 associated pain
CN105873580B (zh) 2013-12-17 2020-08-25 埃斯蒂维制药有限公司 加巴喷丁类化合物与σ受体配体的组合物
EP3082782A1 (en) 2013-12-17 2016-10-26 Laboratorios Del. Dr. Esteve, S.A. SEROTONIN-NOREPINEPHRINE REUPTAKE INHIBITORS (SNRIs) AND SIGMA RECEPTOR LIGANDS COMBINATIONS
TW201607923A (zh) * 2014-07-15 2016-03-01 歌林達有限公司 被取代之氮螺環（４．５）癸烷衍生物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1354554A (en) * 1970-08-31 1974-06-05 Robins Co Inc A H 2-substituted benzimidazoles
EP0402056A3 (en) 1989-06-06 1991-09-04 Beecham Group p.l.c. Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them
US5066662A (en) * 1990-05-21 1991-11-19 Warner-Lambert Company Substituted oxazolidin-2-ones and 1,2,4-oxadiazolin-5-ones and derivatives thereof acting at muscarinic receptors
KR100196440B1 (ko) * 1990-12-05 1999-06-15 로널드 지,미세티취 항균제로서 유용한 7-치환-6-플루오로-1, 4-디하이드로-4-옥소-퀴놀린-3-카르복실산화합물
US5342846A (en) * 1990-12-05 1994-08-30 Synphar Laboratories, Inc. 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds and 7-(substituted triazolyl pyrrolidin-1-yl) 4-oxoquinoline-3-carboxylic acid derivatives useful as antibacterial agents
US5356902A (en) * 1992-11-06 1994-10-18 Eli Lilly And Company Decahydroisoquinoline compounds as excitatory amino acid receptor antagonists
US5446051A (en) * 1994-05-31 1995-08-29 Eli Lilly And Company Aryl-spaced decahydroisoquinoline-3-carboxylic acids as excitatory amino acid receptor antagonists
US5510381A (en) * 1995-05-15 1996-04-23 Warner-Lambert Company Method of treatment of mania and bipolar disorder

Also Published As

Publication number Publication date
CA2371395A1 (en) 2000-12-07
EP1187832A1 (en) 2002-03-20
EP1187832B1 (en) 2002-11-20
DE60000833D1 (de) 2003-01-02
DE60000833T2 (de) 2003-09-18
ES2185591T3 (es) 2003-05-01
JP2003525207A (ja) 2003-08-26
ATE228128T1 (de) 2002-12-15
US6436974B1 (en) 2002-08-20
AU4673300A (en) 2000-12-18
DK1187832T3 (da) 2003-03-10
WO2000073300A1 (en) 2000-12-07
PT1187832E (pt) 2003-03-31

Similar Documents

Publication Publication Date Title
PT888286E (pt) Novos amino acidos ciclicos substituidos como agentes farmaceuticos
PT888325E (pt) Novos amino acidos ciclicos como agentes farmaceuiticos
ES2169848T3 (es) Nuevos aminoacidos ciclicos coronados como agentes farmaceuticos.
ES2185591T3 (es) Amino hererociclos utiles como agentes farmaceuticos.
BR9712651A (pt) ‡cidos gama-aminobutìricos substituìdos com agentes farmacêuticos.
AP2002002517A0 (en) Bicyclic amino acids as pharmaceutical agents.
BR0010961A (pt) Composto, composição farmacêutica, e, métodos para tratar epilepsia, ataques de tontura, hipocinésia, e distúrbios cranianos, distúrbios neurodegenerativos, depressão, ansiedade, pânico, dor, distúrbios neuropatológicos e distúrbios do sono

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9O ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2008 DE 30/06/2009.