ES2185591T3 - Amino hererociclos utiles como agentes farmaceuticos. - Google Patents
Amino hererociclos utiles como agentes farmaceuticos.Info
- Publication number
- ES2185591T3 ES2185591T3 ES00928499T ES00928499T ES2185591T3 ES 2185591 T3 ES2185591 T3 ES 2185591T3 ES 00928499 T ES00928499 T ES 00928499T ES 00928499 T ES00928499 T ES 00928499T ES 2185591 T3 ES2185591 T3 ES 2185591T3
- Authority
- ES
- Spain
- Prior art keywords
- useful
- amino
- hererocicles
- disorders
- pharmaceutical agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Compuesto de la fórmula o una sal derivada farmacéuticamente aceptable donde: R1 y R2 son cada uno independientemente hidrógeno o un alquilo de cadena lineal o ramificada de 3 a 8 átomos de carbono; o R1 y R2 son tomados junto con el átomo de carbono al cual están unidos para formar un anillo carbocíclico de 3 a 8 átomos de carbono; Het es un grupo seleccionado de**Fórmula**
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13709699P | 1999-06-02 | 1999-06-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2185591T3 true ES2185591T3 (es) | 2003-05-01 |
Family
ID=22475823
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES00928499T Expired - Lifetime ES2185591T3 (es) | 1999-06-02 | 2000-04-28 | Amino hererociclos utiles como agentes farmaceuticos. |
Country Status (12)
Country | Link |
---|---|
US (1) | US6436974B1 (es) |
EP (1) | EP1187832B1 (es) |
JP (1) | JP2003525207A (es) |
AT (1) | ATE228128T1 (es) |
AU (1) | AU4673300A (es) |
BR (1) | BR0011236A (es) |
CA (1) | CA2371395A1 (es) |
DE (1) | DE60000833T2 (es) |
DK (1) | DK1187832T3 (es) |
ES (1) | ES2185591T3 (es) |
PT (1) | PT1187832E (es) |
WO (1) | WO2000073300A1 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998003167A1 (en) | 1996-07-24 | 1998-01-29 | Warner-Lambert Company | Isobutylgaba and its derivatives for the treatment of pain |
HUP0300833A3 (en) * | 2000-06-26 | 2009-08-28 | Warner Lambert Co | Gabapentin analogues for treating sleep disorders |
US6855735B2 (en) * | 2002-03-20 | 2005-02-15 | Temple University Of The Commonwealth System Of Higher Education | Ketamine treatment of restless legs syndrome |
US20050209319A1 (en) * | 2004-03-18 | 2005-09-22 | Xenoport, Inc. | Treatment of local pain |
CN101948462A (zh) | 2004-09-20 | 2011-01-19 | 塔加西普特公司 | 具有烟碱性胆碱能受体活性的氮杂螺烯和氮杂螺烷化合物 |
GB0514686D0 (en) * | 2005-07-18 | 2005-08-24 | Novartis Ag | Organic compounds |
EP1820502A1 (en) | 2006-02-10 | 2007-08-22 | Laboratorios Del Dr. Esteve, S.A. | Active substance combination comprising azolylcarbinol compounds |
EP2116539A1 (en) | 2008-04-25 | 2009-11-11 | Laboratorios Del. Dr. Esteve, S.A. | 1-aryl-3-aminoalkoxy-pyrazoles as sigma ligands enhancing analgesic effects of opioids and attenuating the dependency thereof |
EP2116618A1 (en) | 2008-05-09 | 2009-11-11 | Agency for Science, Technology And Research | Diagnosis and treatment of Kawasaki disease |
EP2353591A1 (en) | 2010-02-04 | 2011-08-10 | Laboratorios Del. Dr. Esteve, S.A. | Sigma ligands for potentiating the analgesic effect of opioids and opiates in post-operative pain and attenuating the dependency thereof |
EP2353598A1 (en) | 2010-02-04 | 2011-08-10 | Laboratorios Del. Dr. Esteve, S.A. | Sigma ligands for use in the prevention and/or treatment of postoperative pain |
EP2388005A1 (en) | 2010-05-21 | 2011-11-23 | Laboratorios Del. Dr. Esteve, S.A. | Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy |
EP2415471A1 (en) | 2010-08-03 | 2012-02-08 | Laboratorios Del. Dr. Esteve, S.A. | Use of sigma ligands in opioid-induced hyperalgesia |
EP2524694A1 (en) | 2011-05-19 | 2012-11-21 | Laboratorios Del. Dr. Esteve, S.A. | Use of sigma ligands in diabetes type-2 associated pain |
SG11201604478UA (en) | 2013-12-17 | 2016-07-28 | Esteve Labor Dr | Gabapentinoids and sigma receptor ligands combinations |
JP2016540771A (ja) | 2013-12-17 | 2016-12-28 | ラボラトリオス・デル・ドクトル・エステベ・ソシエダッド・アノニマ | セロトニン−ノルアドレナリン再取り込み阻害薬(snri)およびシグマ受容体リガンドの組み合わせ |
TW201607923A (zh) * | 2014-07-15 | 2016-03-01 | 歌林達有限公司 | 被取代之氮螺環(4.5)癸烷衍生物 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1354554A (en) | 1970-08-31 | 1974-06-05 | Robins Co Inc A H | 2-substituted benzimidazoles |
EP0402056A3 (en) | 1989-06-06 | 1991-09-04 | Beecham Group p.l.c. | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them |
US5066662A (en) * | 1990-05-21 | 1991-11-19 | Warner-Lambert Company | Substituted oxazolidin-2-ones and 1,2,4-oxadiazolin-5-ones and derivatives thereof acting at muscarinic receptors |
DE69132314T2 (de) * | 1990-12-05 | 2000-12-14 | Naeja Pharmaceutical Inc., Edmonton | 7-substituierte-6-fluor-1,4-dihydro-4-oxo-chinolin-3-carbonsäurederivate als antibakterielle wirkstoffe |
US5342846A (en) * | 1990-12-05 | 1994-08-30 | Synphar Laboratories, Inc. | 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds and 7-(substituted triazolyl pyrrolidin-1-yl) 4-oxoquinoline-3-carboxylic acid derivatives useful as antibacterial agents |
US5356902A (en) | 1992-11-06 | 1994-10-18 | Eli Lilly And Company | Decahydroisoquinoline compounds as excitatory amino acid receptor antagonists |
US5446051A (en) | 1994-05-31 | 1995-08-29 | Eli Lilly And Company | Aryl-spaced decahydroisoquinoline-3-carboxylic acids as excitatory amino acid receptor antagonists |
US5510381A (en) * | 1995-05-15 | 1996-04-23 | Warner-Lambert Company | Method of treatment of mania and bipolar disorder |
-
2000
- 2000-04-28 US US09/980,187 patent/US6436974B1/en not_active Expired - Fee Related
- 2000-04-28 WO PCT/US2000/011399 patent/WO2000073300A1/en active IP Right Grant
- 2000-04-28 EP EP00928499A patent/EP1187832B1/en not_active Expired - Lifetime
- 2000-04-28 PT PT00928499T patent/PT1187832E/pt unknown
- 2000-04-28 CA CA002371395A patent/CA2371395A1/en not_active Abandoned
- 2000-04-28 AT AT00928499T patent/ATE228128T1/de not_active IP Right Cessation
- 2000-04-28 BR BR0011236-4A patent/BR0011236A/pt not_active IP Right Cessation
- 2000-04-28 DK DK00928499T patent/DK1187832T3/da active
- 2000-04-28 AU AU46733/00A patent/AU4673300A/en not_active Abandoned
- 2000-04-28 DE DE60000833T patent/DE60000833T2/de not_active Expired - Fee Related
- 2000-04-28 ES ES00928499T patent/ES2185591T3/es not_active Expired - Lifetime
- 2000-04-28 JP JP2000621366A patent/JP2003525207A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
BR0011236A (pt) | 2002-03-05 |
EP1187832A1 (en) | 2002-03-20 |
DK1187832T3 (da) | 2003-03-10 |
CA2371395A1 (en) | 2000-12-07 |
PT1187832E (pt) | 2003-03-31 |
EP1187832B1 (en) | 2002-11-20 |
JP2003525207A (ja) | 2003-08-26 |
DE60000833D1 (de) | 2003-01-02 |
DE60000833T2 (de) | 2003-09-18 |
WO2000073300A1 (en) | 2000-12-07 |
AU4673300A (en) | 2000-12-18 |
ATE228128T1 (de) | 2002-12-15 |
US6436974B1 (en) | 2002-08-20 |
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