MD4349C1 - Compusul N-(3-metoxifenil)-2-(piridin-2-ilmetilen)-hidrazincarbotioamidă - inhibitor al proliferării celulelor MeW-164 ale melanomului uman - Google Patents
Compusul N-(3-metoxifenil)-2-(piridin-2-ilmetilen)-hidrazincarbotioamidă - inhibitor al proliferării celulelor MeW-164 ale melanomului umanInfo
- Publication number
- MD4349C1 MD4349C1 MDA20140062A MD20140062A MD4349C1 MD 4349 C1 MD4349 C1 MD 4349C1 MD A20140062 A MDA20140062 A MD A20140062A MD 20140062 A MD20140062 A MD 20140062A MD 4349 C1 MD4349 C1 MD 4349C1
- Authority
- MD
- Moldova
- Prior art keywords
- human melanoma
- compound
- hydrazinecarbothioamide
- ylmethylene
- mew
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
Invenţia se referă la chimie şi medicină, şi anume la un compus organic din clasa tioamidelor care poate găsi aplicare în medicină în calitate de preparat citostatic la profilaxia şi tratamentul melanomului uman.Esenţa invenţiei constă în sinteza compusului N-(3-metoxifenil)-2-(piridin-2-ilmetilen)-hidrazincarbotioamidă cu formula:,care manifestă proprietatea de inhibare a proliferării celulelor MeW-164 ale melanomului uman.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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MDA20140062A MD4349C1 (ro) | 2014-06-23 | 2014-06-23 | Compusul N-(3-metoxifenil)-2-(piridin-2-ilmetilen)-hidrazincarbotioamidă - inhibitor al proliferării celulelor MeW-164 ale melanomului uman |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MDA20140062A MD4349C1 (ro) | 2014-06-23 | 2014-06-23 | Compusul N-(3-metoxifenil)-2-(piridin-2-ilmetilen)-hidrazincarbotioamidă - inhibitor al proliferării celulelor MeW-164 ale melanomului uman |
Publications (2)
Publication Number | Publication Date |
---|---|
MD4349B1 MD4349B1 (ro) | 2015-05-31 |
MD4349C1 true MD4349C1 (ro) | 2015-12-31 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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MDA20140062A MD4349C1 (ro) | 2014-06-23 | 2014-06-23 | Compusul N-(3-metoxifenil)-2-(piridin-2-ilmetilen)-hidrazincarbotioamidă - inhibitor al proliferării celulelor MeW-164 ale melanomului uman |
Country Status (1)
Country | Link |
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MD (1) | MD4349C1 (ro) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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MD4520C1 (ro) * | 2016-12-16 | 2018-05-31 | Государственный Университет Молд0 | N-(4-butoxifenil)-2-(piridin-2-ilmetiliden)hidrazincarbotioamida în calitate de inhibitor al proliferării celulelor T-47D ale cancerului mamar |
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MD3655G2 (ro) * | 2007-09-03 | 2009-02-28 | Государственный Университет Молд0 | Inhibitor al leucemiei mieloide umane în bază de bis(2-hidroxi-8-fenil-triciclo/7.3.1.0.2,7/tridecan-13-on-tiosemicarbazonato)cupru |
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MD3996B1 (ro) * | 2009-05-25 | 2009-12-31 | Universitatea De Stat Din Moldova | Perclorati de 5-R-saliciliden-4-feniltiosemicarbazonato(1-)-aquacupru(II) ce poseda proprietati de inhibitori ai activitatii enzimei 17Beta-HSD (tipul 1) |
MD3995B1 (ro) * | 2009-05-11 | 2009-12-31 | Universitatea De Stat Din Moldova | Utilizare a di(µ-Ofenoxi)-di{[2-(4-aminobenzensulfamido)-5-etil-1,3,4-tiadiazol]-3,5-dibromosalicilidentiosemicarbazonato(-1)-cupru} in calitate de inhibitor al proliferarii celulelor T-47D ale cancerului mamar |
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WO2010006438A1 (en) * | 2008-07-17 | 2010-01-21 | Critical Outcome Technologies Inc. | Thiosemicarbazone inhibitor compounds and cancer treatment methods |
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MD4190B1 (ro) * | 2011-06-16 | 2012-12-31 | Univ De Stat Din Moldova | Inhibitor al leucemiei mieloide umane în baza de {bis[2-(3,5-dibromo-2-hidroxifenil)-2-oxoetil-piperidin-1-carboditioato(1−)-O,O']cupru} |
MD4215B1 (ro) * | 2012-07-09 | 2013-04-30 | Univ De Stat Din Moldova | Inhibitor al leucemiei mieloide umane în baza de N-(4-(5-(piridin-2-il)-4,5-dihidro-1H-pirazol-3-il)fenil)-2-(piridin-2-ilmetilen)-hidrazincarbotioamida |
-
2014
- 2014-06-23 MD MDA20140062A patent/MD4349C1/ro not_active IP Right Cessation
Patent Citations (12)
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CN101260121A (zh) * | 2007-03-07 | 2008-09-10 | 卡南吉医药科技(上海)有限公司 | 杂芳环缩氨基硫脲与过渡金属的络合物及其在制备抗肿瘤药物中的应用 |
MD3655G2 (ro) * | 2007-09-03 | 2009-02-28 | Государственный Университет Молд0 | Inhibitor al leucemiei mieloide umane în bază de bis(2-hidroxi-8-fenil-triciclo/7.3.1.0.2,7/tridecan-13-on-tiosemicarbazonato)cupru |
MD3771G2 (ro) * | 2008-04-30 | 2009-07-31 | Государственный Университет Молд0 | Inhibitori ai enzimei 17β-HSD, stimulatoare a multiplicării celulelor cancerului prostatei |
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MD3890G2 (ro) * | 2008-09-08 | 2009-12-31 | Государственный Университет Молд0 | Inhibitori ai leucemiei mieloide umane în baza compuşilor coordinativi ai cuprului(II) cu salicilidentiosemicarbazide |
MD3995B1 (ro) * | 2009-05-11 | 2009-12-31 | Universitatea De Stat Din Moldova | Utilizare a di(µ-Ofenoxi)-di{[2-(4-aminobenzensulfamido)-5-etil-1,3,4-tiadiazol]-3,5-dibromosalicilidentiosemicarbazonato(-1)-cupru} in calitate de inhibitor al proliferarii celulelor T-47D ale cancerului mamar |
MD3996B1 (ro) * | 2009-05-25 | 2009-12-31 | Universitatea De Stat Din Moldova | Perclorati de 5-R-saliciliden-4-feniltiosemicarbazonato(1-)-aquacupru(II) ce poseda proprietati de inhibitori ai activitatii enzimei 17Beta-HSD (tipul 1) |
MD4190B1 (ro) * | 2011-06-16 | 2012-12-31 | Univ De Stat Din Moldova | Inhibitor al leucemiei mieloide umane în baza de {bis[2-(3,5-dibromo-2-hidroxifenil)-2-oxoetil-piperidin-1-carboditioato(1−)-O,O']cupru} |
MD4215B1 (ro) * | 2012-07-09 | 2013-04-30 | Univ De Stat Din Moldova | Inhibitor al leucemiei mieloide umane în baza de N-(4-(5-(piridin-2-il)-4,5-dihidro-1H-pirazol-3-il)fenil)-2-(piridin-2-ilmetilen)-hidrazincarbotioamida |
Non-Patent Citations (4)
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Giorgio Pelosi. Thiosemicarbazone Metal Complexes: from structure to activity. The Open Crystallography Journal, 2010, 3, pag. 16-28, (regăsit în Internet la 2015.02.10 URL: < <http://benthamopen.com/contents/pdf/TOCRYJ/TOCRYJ-3-16.pdf>>) * |
Also Published As
Publication number | Publication date |
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MD4349B1 (ro) | 2015-05-31 |
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Legal Events
Date | Code | Title | Description |
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FG4A | Patent for invention issued | ||
KA4A | Patent for invention lapsed due to non-payment of fees (with right of restoration) | ||
MM4A | Patent for invention definitely lapsed due to non-payment of fees |