MX2016002423A - Composiciones y metodos de diagnostico para el tratamiento de glioblastoma. - Google Patents

Composiciones y metodos de diagnostico para el tratamiento de glioblastoma.

Info

Publication number
MX2016002423A
MX2016002423A MX2016002423A MX2016002423A MX2016002423A MX 2016002423 A MX2016002423 A MX 2016002423A MX 2016002423 A MX2016002423 A MX 2016002423A MX 2016002423 A MX2016002423 A MX 2016002423A MX 2016002423 A MX2016002423 A MX 2016002423A
Authority
MX
Mexico
Prior art keywords
compositions
glioblastoma
treatment
diagnostic methods
methods
Prior art date
Application number
MX2016002423A
Other languages
English (en)
Inventor
Heidi Phillips
Carlos Bais
Bourgon Richard
Sandmann Thomas
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2016002423A publication Critical patent/MX2016002423A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Abstract

La presente invención proporciona métodos y composiciones para detectar la expresión de uno o más biomarcadores para identificar y tratar pacientes que padecen glioblastomas, que probablemente responden a la terapia con un antagonista de VEGF. La invención también proporciona kits y artículos de fabricación para utilizar en los métodos.
MX2016002423A 2013-08-30 2014-08-29 Composiciones y metodos de diagnostico para el tratamiento de glioblastoma. MX2016002423A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361872346P 2013-08-30 2013-08-30
PCT/US2014/053500 WO2015031808A2 (en) 2013-08-30 2014-08-29 Diagnostic methods and compositions for treatment of glioblastoma

Publications (1)

Publication Number Publication Date
MX2016002423A true MX2016002423A (es) 2016-08-19

Family

ID=52583566

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016002423A MX2016002423A (es) 2013-08-30 2014-08-29 Composiciones y metodos de diagnostico para el tratamiento de glioblastoma.

Country Status (15)

Country Link
US (1) US10456470B2 (es)
EP (1) EP3038646B1 (es)
JP (2) JP6664323B2 (es)
KR (1) KR20160048196A (es)
CN (1) CN105611940A (es)
AR (1) AR097500A1 (es)
AU (1) AU2014312079B2 (es)
BR (1) BR112016004305A2 (es)
CA (1) CA2921515A1 (es)
HK (1) HK1221422A1 (es)
IL (1) IL244089A0 (es)
MX (1) MX2016002423A (es)
RU (1) RU2706968C2 (es)
SG (1) SG11201601471SA (es)
WO (1) WO2015031808A2 (es)

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CN111684078B (zh) * 2018-02-12 2024-04-19 豪夫迈·罗氏有限公司 通过评价肿瘤遗传异质性来预测对治疗的应答的方法
CN109762903B (zh) * 2019-01-31 2022-02-01 山东大学齐鲁医院 miR-1246和/或TERF2IP在诊治胶质瘤中的应用
KR102256859B1 (ko) * 2019-03-12 2021-05-27 건국대학교 산학협력단 알츠하이머병의 진단용 조성물
KR102078500B1 (ko) * 2019-03-12 2020-02-17 건국대학교 산학협력단 알츠하이머병의 진단용 조성물
CN110412277B (zh) * 2019-06-26 2022-09-09 四川大学华西医院 Snap91自身抗体检测试剂在制备肺癌筛查试剂盒中的用途
WO2021034091A1 (ko) * 2019-08-19 2021-02-25 재단법인 아산사회복지재단 교모세포종의 진단 방법
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CN111996251B (zh) * 2020-06-19 2024-03-26 皖南医学院第一附属医院（皖南医学院弋矶山医院） 一种恶性胶质瘤生物标志物的应用
CN114075604B (zh) * 2022-01-18 2022-04-08 天津医科大学总医院 胶质母细胞瘤预后预测评分模型及其在指导临床精准诊疗中的应用

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Also Published As

Publication number Publication date
EP3038646A2 (en) 2016-07-06
KR20160048196A (ko) 2016-05-03
BR112016004305A2 (pt) 2017-10-17
AR097500A1 (es) 2016-03-16
CA2921515A1 (en) 2015-03-05
WO2015031808A2 (en) 2015-03-05
HK1221422A1 (zh) 2017-06-02
US10456470B2 (en) 2019-10-29
RU2706968C2 (ru) 2019-11-21
AU2014312079B2 (en) 2020-01-16
JP2020062012A (ja) 2020-04-23
US20150064178A1 (en) 2015-03-05
JP2016529903A (ja) 2016-09-29
WO2015031808A3 (en) 2015-04-23
EP3038646B1 (en) 2020-03-04
RU2016111161A (ru) 2017-10-05
IL244089A0 (en) 2016-04-21
SG11201601471SA (en) 2016-03-30
CN105611940A (zh) 2016-05-25
EP3038646A4 (en) 2017-07-12
JP6664323B2 (ja) 2020-03-13
AU2014312079A1 (en) 2016-03-03

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