MX2015016123A - Sistema de liberación transdérmico. - Google Patents
Sistema de liberación transdérmico.Info
- Publication number
- MX2015016123A MX2015016123A MX2015016123A MX2015016123A MX2015016123A MX 2015016123 A MX2015016123 A MX 2015016123A MX 2015016123 A MX2015016123 A MX 2015016123A MX 2015016123 A MX2015016123 A MX 2015016123A MX 2015016123 A MX2015016123 A MX 2015016123A
- Authority
- MX
- Mexico
- Prior art keywords
- buprenorphine
- sensitive adhesive
- adhesive layer
- pressure
- acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4748—Quinolines; Isoquinolines forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive plasters or dressings
- A61F13/0246—Adhesive plasters or dressings characterised by the skin adhering layer
- A61F13/0256—Adhesive plasters or dressings characterised by the skin adhering layer characterized by the parametric properties of the adhesive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Abstract
La invención se relaciona con sistema terapéutico transdérmico para la administración transdérmica de buprenorfina, comprendiendo una estructura de capa auto-adhesiva conteniendo buprenorfina comprendiendo A) una capa de respaldo impermeable a la buprenorfina, y B) una capa adhesiva sensible a la presión conteniendo buprenorfina sobre dicha capa de respaldo impermeable a la buprenorfina, la capa adhesiva comprendiendo a) al menos un adhesivo sensible a la presión de base polimérica, b) una cantidad efectiva analgésicamente de base de buprenorfina o una sal farmacéuticamente aceptable de la misma, c) una sustancia que aumenta la viscosidad en una cantidad de alrededor de 0,1% a alrededor de 8% de dicha capa adhesiva sensible a la presión conteniendo buprenorfina, y d) un ácido carboxílico seleccionado del grupo consistente de ácido oleico, ácido linoleico, ácido linolénico, ácido levulínico y mezclas de los mismos, en una cantidad suficiente para que dicha cantidad efectiva analgésicamente de buprenorfina sea solubilizada en él para formar una mezcla incluyendo dicha sustancia que aumenta la viscosidad , y donde la mezcla conteniendo ácido carboxílico-, buprenorfina- y sustancia que aumenta la viscosidad forma depósitos dispersos en dicho adhesivo sensible a la presión, y donde dicha capa adhesiva sensible a la presión conteniendo buprenorfina es la capa en contacto con la piel.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361830975P | 2013-06-04 | 2013-06-04 | |
PCT/EP2014/061567 WO2014195352A1 (en) | 2013-06-04 | 2014-06-04 | Transdermal delivery system |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015016123A true MX2015016123A (es) | 2016-07-21 |
MX362614B MX362614B (es) | 2019-01-28 |
Family
ID=51022809
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015016123A MX362614B (es) | 2013-06-04 | 2014-06-04 | Sistema de liberación transdérmico. |
Country Status (34)
Country | Link |
---|---|
US (6) | US20160008294A1 (es) |
EP (2) | EP2810646B1 (es) |
JP (1) | JP6559121B2 (es) |
KR (1) | KR102302505B1 (es) |
CN (1) | CN105377245B (es) |
AP (1) | AP2015008920A0 (es) |
AR (1) | AR096521A1 (es) |
AU (1) | AU2014276910B2 (es) |
BR (1) | BR112015029920A2 (es) |
CA (1) | CA2914425C (es) |
CL (1) | CL2015003377A1 (es) |
CR (1) | CR20150647A (es) |
CY (1) | CY1118054T1 (es) |
DE (1) | DE112014002664T5 (es) |
DK (1) | DK2810646T3 (es) |
EA (1) | EA201592246A1 (es) |
ES (1) | ES2599802T3 (es) |
GB (1) | GB2529789A (es) |
HK (2) | HK1204766A1 (es) |
HU (1) | HUE031662T2 (es) |
LT (1) | LT2810646T (es) |
MA (1) | MA38698B1 (es) |
MX (1) | MX362614B (es) |
NI (1) | NI201500170A (es) |
PE (1) | PE20160002A1 (es) |
PH (1) | PH12015502550A1 (es) |
PL (1) | PL2810646T3 (es) |
PT (1) | PT2810646T (es) |
SG (1) | SG11201509218SA (es) |
SI (1) | SI2810646T1 (es) |
TN (1) | TN2015000493A1 (es) |
TW (1) | TW201509416A (es) |
WO (1) | WO2014195352A1 (es) |
ZA (1) | ZA201509309B (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102006054731B4 (de) | 2006-11-21 | 2013-02-28 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie |
MX352795B (es) | 2011-12-12 | 2017-12-07 | Lts Lohmann Therapie Systeme Ag | Sistema de administracion transdermica que comprende buprenorfina. |
TW201431570A (zh) | 2012-11-22 | 2014-08-16 | Ucb Pharma Gmbh | 用於經皮投服羅替戈汀(Rotigotine)之多天式貼片 |
JP6559121B2 (ja) | 2013-06-04 | 2019-08-14 | エルテーエス ローマン テラピー−ジステーメ アーゲー | 経皮送達システム |
CA2916183C (en) | 2013-07-03 | 2022-03-29 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system with electronic component |
US11426359B2 (en) | 2014-05-20 | 2022-08-30 | Lts Lohmann Therapie-Systeme Ag | Method for adjusting the release of active agent in a transdermal delivery system |
CN106456566B (zh) | 2014-05-20 | 2020-06-16 | Lts勒曼治疗系统股份公司 | 含罗替戈汀的经皮递送系统 |
US11752110B2 (en) | 2014-05-20 | 2023-09-12 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system including an interface mediator |
MA45902A (fr) | 2015-03-10 | 2019-06-19 | Rhodes Tech | Sel d'acã‰tate de bruprã‰norphine et procã‰dã‰s pour la prã‰paration de bruprã‰norphine |
EP3349737A4 (en) * | 2015-09-14 | 2019-05-15 | Amneal Pharmaceuticals LLC | SYSTEM FOR TRANSDERING |
AR102214A1 (es) * | 2015-10-08 | 2017-02-15 | Amarin Tech S A | Un dispositivo para la administración transdermal de buprenorfina |
US10486690B2 (en) * | 2016-12-14 | 2019-11-26 | Bendix Commerical Vehicle Systems, Llc | Front end motor-generator system and hybrid electric vehicle operating method |
RU2764443C2 (ru) | 2016-12-20 | 2022-01-17 | Лтс Ломанн Терапи-Систем Аг | Трансдермальная терапевтическая система, содержащая азенапин и полисилоксан или полиизобутилен |
EP3558275A1 (en) | 2016-12-20 | 2019-10-30 | LTS Lohmann Therapie-Systeme AG | Transdermal therapeutic system containing asenapine |
US20180221297A1 (en) * | 2017-02-03 | 2018-08-09 | Kirti H. Valia | System and Method for Improving Adhesion of Transdermal Delivery Devices |
JP2020525545A (ja) | 2017-06-26 | 2020-08-27 | エルテーエス ローマン テラピー−ジステーメ アーゲー | アセナピンおよびシリコーンアクリルハイブリッドポリマーを含有する経皮治療システム |
US20200246276A1 (en) | 2017-09-04 | 2020-08-06 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system including an emulsifier |
WO2019064026A1 (en) | 2017-09-29 | 2019-04-04 | Orexo Ab | NEW PHARMACEUTICAL COMPOSITIONS |
WO2019166572A1 (en) | 2018-02-28 | 2019-09-06 | Pharming Intellectual Property B.V. | Pharmaceutical system for transdermal administration of a c1 -esterase inhibitor |
BR112020017484A2 (pt) * | 2018-03-13 | 2020-12-22 | Lts Lohmann Therapie-Systeme Ag | Sistema terapêutico transdérmico para a administração transdérmica de buprenorfina compreendendo um polímero híbrido de acrílico e silicone |
WO2019209940A1 (en) * | 2018-04-25 | 2019-10-31 | Shinkei Therapeutics Llc | Tetrabenazine transdermal delivery device |
KR20210022656A (ko) | 2018-06-20 | 2021-03-03 | 에르테에스 로만 테라피-시스테메 아게 | 아세나핀을 함유하는 경피 치료 시스템 |
GB201904767D0 (en) | 2019-04-04 | 2019-05-22 | Orexo Ab | New pharmaceutical compositions |
CN113952319A (zh) * | 2021-11-30 | 2022-01-21 | 烟台大学 | 一种含丁丙诺啡的骨架型透皮贴剂及其制备方法 |
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MX352795B (es) | 2011-12-12 | 2017-12-07 | Lts Lohmann Therapie Systeme Ag | Sistema de administracion transdermica que comprende buprenorfina. |
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AU2013205080B2 (en) | 2012-12-12 | 2016-07-07 | Lts Lohmann Therapie-Systeme Ag | Transdermal Delivery System |
JP6559121B2 (ja) | 2013-06-04 | 2019-08-14 | エルテーエス ローマン テラピー−ジステーメ アーゲー | 経皮送達システム |
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2014
- 2014-06-04 JP JP2016517285A patent/JP6559121B2/ja active Active
- 2014-06-04 DK DK14171110.1T patent/DK2810646T3/en active
- 2014-06-04 US US14/772,474 patent/US20160008294A1/en not_active Abandoned
- 2014-06-04 PT PT141711101T patent/PT2810646T/pt unknown
- 2014-06-04 GB GB1522307.6A patent/GB2529789A/en not_active Withdrawn
- 2014-06-04 MA MA38698A patent/MA38698B1/fr unknown
- 2014-06-04 TN TN2015000493A patent/TN2015000493A1/en unknown
- 2014-06-04 CN CN201480032321.8A patent/CN105377245B/zh active Active
- 2014-06-04 WO PCT/EP2014/061567 patent/WO2014195352A1/en active Application Filing
- 2014-06-04 AU AU2014276910A patent/AU2014276910B2/en active Active
- 2014-06-04 SI SI201430078A patent/SI2810646T1/sl unknown
- 2014-06-04 KR KR1020157037128A patent/KR102302505B1/ko active IP Right Grant
- 2014-06-04 ES ES14171110.1T patent/ES2599802T3/es active Active
- 2014-06-04 AP AP2015008920A patent/AP2015008920A0/xx unknown
- 2014-06-04 EP EP14171110.1A patent/EP2810646B1/en active Active
- 2014-06-04 AR ARP140102182A patent/AR096521A1/es unknown
- 2014-06-04 BR BR112015029920A patent/BR112015029920A2/pt not_active Application Discontinuation
- 2014-06-04 MX MX2015016123A patent/MX362614B/es active IP Right Grant
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- 2014-06-04 CA CA2914425A patent/CA2914425C/en active Active
- 2014-06-04 LT LTEP14171110.1T patent/LT2810646T/lt unknown
- 2014-06-04 PL PL14171110T patent/PL2810646T3/pl unknown
- 2014-06-04 DE DE112014002664.6T patent/DE112014002664T5/de not_active Withdrawn
- 2014-06-04 TW TW103119370A patent/TW201509416A/zh unknown
- 2014-06-04 SG SG11201509218SA patent/SG11201509218SA/en unknown
- 2014-06-04 PE PE2015002556A patent/PE20160002A1/es not_active Application Discontinuation
- 2014-06-04 EP EP16173124.5A patent/EP3106153A1/en not_active Withdrawn
- 2014-06-04 HU HUE14171110A patent/HUE031662T2/en unknown
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2015
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- 2015-12-08 CR CR20150647A patent/CR20150647A/es unknown
- 2015-12-16 US US14/970,641 patent/US20160101100A1/en not_active Abandoned
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2016
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2017
- 2017-01-24 US US15/414,138 patent/US20170128384A1/en not_active Abandoned
- 2017-11-22 US US15/820,978 patent/US20180092905A1/en not_active Abandoned
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2020
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