CL2015003377A1 - Sistema de liberación transdérmico. - Google Patents

Sistema de liberación transdérmico.

Info

Publication number
CL2015003377A1
CL2015003377A1 CL2015003377A CL2015003377A CL2015003377A1 CL 2015003377 A1 CL2015003377 A1 CL 2015003377A1 CL 2015003377 A CL2015003377 A CL 2015003377A CL 2015003377 A CL2015003377 A CL 2015003377A CL 2015003377 A1 CL2015003377 A1 CL 2015003377A1
Authority
CL
Chile
Prior art keywords
release system
buprenorfine
transdermal release
adhesive layer
transdermal therapeutic
Prior art date
Application number
CL2015003377A
Other languages
English (en)
Inventor
Gabriel Wauer
Thomas Hille
Frank Seibertz
Shu-Lun Weinheimer
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51022809&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2015003377(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Publication of CL2015003377A1 publication Critical patent/CL2015003377A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive plasters or dressings
    • A61F13/0246—Adhesive plasters or dressings characterised by the skin adhering layer
    • A61F13/0256—Adhesive plasters or dressings characterised by the skin adhering layer characterized by the parametric properties of the adhesive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4748—Quinolines; Isoquinolines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Abstract

SISTEMA TERAPEUTICO TRANSDERMICO DE BUPRENORFINA QUE COMPRENDE UNA ESTRUCTURA DE CAPA AUTO-ADHESIVA COMPRENDIENDO A) UNA CAPA DE RESPALDO IMPERMEABLE A LA BUPRENORFINA Y B) UNA CAPA ADHESIVA SENSIBLE A LA PRESION CONTENIENDO BUPRENORFINA SOBRE DICHA CAPA DE RESPALDO; SU METODO DE PREPARACION; Y CONJUNTO DE DOS A CINCO SISTEMAS TERAPEUTICOS TRANSDERMICOS; Y USO PARA EL TRATAMIENTO DEL DOLOR.
CL2015003377A 2013-06-04 2015-11-17 Sistema de liberación transdérmico. CL2015003377A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361830975P 2013-06-04 2013-06-04

Publications (1)

Publication Number Publication Date
CL2015003377A1 true CL2015003377A1 (es) 2016-06-17

Family

ID=51022809

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015003377A CL2015003377A1 (es) 2013-06-04 2015-11-17 Sistema de liberación transdérmico.

Country Status (34)

Country Link
US (6) US20160008294A1 (es)
EP (2) EP2810646B1 (es)
JP (1) JP6559121B2 (es)
KR (1) KR102302505B1 (es)
CN (1) CN105377245B (es)
AP (1) AP2015008920A0 (es)
AR (1) AR096521A1 (es)
AU (1) AU2014276910B2 (es)
BR (1) BR112015029920A2 (es)
CA (1) CA2914425C (es)
CL (1) CL2015003377A1 (es)
CR (1) CR20150647A (es)
CY (1) CY1118054T1 (es)
DE (1) DE112014002664T5 (es)
DK (1) DK2810646T3 (es)
EA (1) EA201592246A1 (es)
ES (1) ES2599802T3 (es)
GB (1) GB2529789A (es)
HK (2) HK1204766A1 (es)
HU (1) HUE031662T2 (es)
LT (1) LT2810646T (es)
MA (1) MA38698B1 (es)
MX (1) MX362614B (es)
NI (1) NI201500170A (es)
PE (1) PE20160002A1 (es)
PH (1) PH12015502550A1 (es)
PL (1) PL2810646T3 (es)
PT (1) PT2810646T (es)
SG (1) SG11201509218SA (es)
SI (1) SI2810646T1 (es)
TN (1) TN2015000493A1 (es)
TW (1) TW201509416A (es)
WO (1) WO2014195352A1 (es)
ZA (1) ZA201509309B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006054731B4 (de) 2006-11-21 2013-02-28 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie
MX352795B (es) 2011-12-12 2017-12-07 Lts Lohmann Therapie Systeme Ag Sistema de administracion transdermica que comprende buprenorfina.
TW201431570A (zh) 2012-11-22 2014-08-16 Ucb Pharma Gmbh 用於經皮投服羅替戈汀（Ｒｏｔｉｇｏｔｉｎｅ）之多天式貼片
JP6559121B2 (ja) 2013-06-04 2019-08-14 エルテーエス ローマン テラピー−ジステーメ アーゲー 経皮送達システム
CA2916183C (en) 2013-07-03 2022-03-29 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system with electronic component
US11426359B2 (en) 2014-05-20 2022-08-30 Lts Lohmann Therapie-Systeme Ag Method for adjusting the release of active agent in a transdermal delivery system
CN106456566B (zh) 2014-05-20 2020-06-16 Lts勒曼治疗系统股份公司 含罗替戈汀的经皮递送系统
US11752110B2 (en) 2014-05-20 2023-09-12 Lts Lohmann Therapie-Systeme Ag Transdermal delivery system including an interface mediator
MA45902A (fr) 2015-03-10 2019-06-19 Rhodes Tech Sel d'acã‰tate de bruprã‰norphine et procã‰dã‰s pour la prã‰paration de bruprã‰norphine
EP3349737A4 (en) * 2015-09-14 2019-05-15 Amneal Pharmaceuticals LLC SYSTEM FOR TRANSDERING
AR102214A1 (es) * 2015-10-08 2017-02-15 Amarin Tech S A Un dispositivo para la administración transdermal de buprenorfina
US10486690B2 (en) * 2016-12-14 2019-11-26 Bendix Commerical Vehicle Systems, Llc Front end motor-generator system and hybrid electric vehicle operating method
RU2764443C2 (ru) 2016-12-20 2022-01-17 Лтс Ломанн Терапи-Систем Аг Трансдермальная терапевтическая система, содержащая азенапин и полисилоксан или полиизобутилен
EP3558275A1 (en) 2016-12-20 2019-10-30 LTS Lohmann Therapie-Systeme AG Transdermal therapeutic system containing asenapine
US20180221297A1 (en) * 2017-02-03 2018-08-09 Kirti H. Valia System and Method for Improving Adhesion of Transdermal Delivery Devices
JP2020525545A (ja) 2017-06-26 2020-08-27 エルテーエス ローマン テラピー−ジステーメ アーゲー アセナピンおよびシリコーンアクリルハイブリッドポリマーを含有する経皮治療システム
US20200246276A1 (en) 2017-09-04 2020-08-06 Lts Lohmann Therapie-Systeme Ag Transdermal delivery system including an emulsifier
WO2019064026A1 (en) 2017-09-29 2019-04-04 Orexo Ab NEW PHARMACEUTICAL COMPOSITIONS
WO2019166572A1 (en) 2018-02-28 2019-09-06 Pharming Intellectual Property B.V. Pharmaceutical system for transdermal administration of a c1 -esterase inhibitor
BR112020017484A2 (pt) * 2018-03-13 2020-12-22 Lts Lohmann Therapie-Systeme Ag Sistema terapêutico transdérmico para a administração transdérmica de buprenorfina compreendendo um polímero híbrido de acrílico e silicone
WO2019209940A1 (en) * 2018-04-25 2019-10-31 Shinkei Therapeutics Llc Tetrabenazine transdermal delivery device
KR20210022656A (ko) 2018-06-20 2021-03-03 에르테에스 로만 테라피-시스테메 아게 아세나핀을 함유하는 경피 치료 시스템
GB201904767D0 (en) 2019-04-04 2019-05-22 Orexo Ab New pharmaceutical compositions
CN113952319A (zh) * 2021-11-30 2022-01-21 烟台大学 一种含丁丙诺啡的骨架型透皮贴剂及其制备方法

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1136214A (en) 1965-06-15 1968-12-11 Reckitt & Sons Ltd Thebaine and oripavine derivatives
US3474101A (en) 1960-09-05 1969-10-21 Reckitt & Sons Ltd Thebaine and oripavine derivatives
US4588580B2 (en) 1984-07-23 1999-02-16 Alaz Corp Transdermal administration of fentanyl and device therefor
US4806341A (en) 1985-02-25 1989-02-21 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit for narcotic analgesics and antagonists and process for administration
CA2002299A1 (en) 1988-11-10 1990-05-10 Eugene G. Drust Compositions for the transdermal delivery of buprenorphine salts
US5788983A (en) 1989-04-03 1998-08-04 Rutgers, The State University Of New Jersey Transdermal controlled delivery of pharmaceuticals at variable dosage rates and processes
US5240711A (en) 1989-11-29 1993-08-31 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system comprising as active component buprenorphine
DE3939376C1 (es) 1989-11-29 1991-05-08 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg, 5450 Neuwied, De
US5069909A (en) 1990-06-20 1991-12-03 Cygnus Therapeutic Systems Transdermal administration of buprenorphine
DE4446600A1 (de) 1994-12-24 1996-06-27 Lohmann Therapie Syst Lts Transdermale Resorption von Wirkstoffen aus unterkühlten Schmelzen
US6365178B1 (en) * 1996-09-06 2002-04-02 Watson Pharmaceuticals, Inc. Method of making pressure sensitive adhesive matrix patches for transdermal drug delivery using hydrophilic salts of drugs and hydrophobic pressure sensitive adhesive dispersions
US5968547A (en) 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
DE19738855C2 (de) * 1997-09-05 2001-01-04 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit haftklebender Reservoirschicht und unidirektional elastischer Rückschicht
DE19922662C1 (de) 1999-05-18 2000-12-28 Sanol Arznei Schwarz Gmbh Transdermales therapeutisches System (TTS) Tolterodin enthaltend
DE19958554C2 (de) 1999-07-02 2002-06-13 Lohmann Therapie Syst Lts Mikroreservoirsystem auf Basis von Polysiloxanen und ambiphilen Lösemitteln und ihre Herstellung
MXPA02000118A (es) 1999-07-02 2003-02-27 Lohmann Therapie Syst Lts Sistema de microdepositos a base de polisiloxanos y solventes ambifilos.
MEP48308A (en) 2000-02-08 2011-05-10 Euro Celtique Sa Tamper-resistant oral opioid agonist formulations
US6682757B1 (en) 2000-11-16 2004-01-27 Euro-Celtique, S.A. Titratable dosage transdermal delivery system
JP2004525960A (ja) 2001-02-16 2004-08-26 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 尿失禁、特に切迫尿失禁の治療用経皮デリバリーディバイスの製造にブプレノルフィンを使用する方法
DE10141651B4 (de) * 2001-08-24 2007-02-15 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System (TTS) mit dem Wirkstoff Fentanyl und Verfahren zu seiner Herstellung
WO2003043657A1 (en) 2001-11-19 2003-05-30 Control Delivery Systems, Inc. Topical delivery of codrugs
US20050118245A1 (en) 2002-03-27 2005-06-02 Wilsmann Klaus M. Assembled unit consisting of individually separable, transdermal, therapeutic systems
DE10213772A1 (de) 2002-03-27 2003-10-09 Gruenenthal Gmbh Zusammenhängende Einheit aus vereinzelbaren transdermalen therapeutischen Systemen
US20050191340A1 (en) 2002-08-09 2005-09-01 Gruenenthal Gmbh Opioid-receptor antagonists in transdermal systems having buprenorphine
AU2003283055A1 (en) 2002-08-09 2004-02-25 Grunenthal Gmbh Opioid-receptor antagonists in transdermal systems having buprenorphine
US7270830B2 (en) 2002-12-13 2007-09-18 Purdue Pharma L.P. Transdermal buprenorphine dosage regimen for analgesia
RU2324372C2 (ru) 2003-03-25 2008-05-20 Моринда, Инк. Селективное ингибирование продукции эстрогена и обеспечение эстрогенного действия в организме человека
NZ541956A (en) * 2003-04-14 2008-09-26 Lohmann Therapie Syst Lts Therapeutic patch with polysiloxane matrix comprising capsaicin
US7182955B2 (en) 2003-04-30 2007-02-27 3M Innovative Properties Company Abuse-resistant transdermal dosage form
US8790689B2 (en) 2003-04-30 2014-07-29 Purdue Pharma L.P. Tamper resistant transdermal dosage form
US8007737B2 (en) * 2004-04-14 2011-08-30 Wyeth Use of antioxidants to prevent oxidation and reduce drug degradation in drug eluting medical devices
DE102004019916A1 (de) * 2004-04-21 2005-11-17 Grünenthal GmbH Gegen Missbrauch gesichertes wirkstoffhaltiges Pflaster
DE102004045599A1 (de) 2004-09-17 2006-03-23 Grünenthal GmbH System zur sequentiellen, transdermalen Verabreichung von systemisch wirksamen Substanzen
DE102004062647A1 (de) 2004-12-21 2006-06-29 Kronotec Ag Holzfaserdämmstoffplatte bzw.- matte
DE102004062614B4 (de) 2004-12-24 2011-12-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit aktivierbarer Übersättigung und kontrollierter Permeationförderung sowie Verfahren zu dessen Herstellung
DE102006026578B4 (de) 2006-06-08 2009-01-08 Lts Lohmann Therapie-Systeme Ag Wirkstoffpartikelhaltiges Transdermales Therapeutisches System mit erhöhtem Wirkstofffluss und Verfahren zu seiner Herstellung sowie Verwendung
DE102006054732B4 (de) 2006-11-21 2010-12-30 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit Ionenpaar-Mikroreservoiren
DE102006054731B4 (de) 2006-11-21 2013-02-28 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie
JP5235384B2 (ja) 2007-11-08 2013-07-10 リンテック株式会社 貼付シート
GB0815435D0 (en) * 2008-08-22 2008-10-01 Camurus Ab Formulations
EP2366388A1 (de) * 2010-03-17 2011-09-21 Ratiopharm GmbH Nicht-okklusives transdermales therapeutisches System zur Verabreichung von Buprenorphin
CN103200944B (zh) * 2010-11-17 2016-05-04 赫克萨尔股份公司 包含丁丙诺啡的经皮治疗系统
MX352795B (es) 2011-12-12 2017-12-07 Lts Lohmann Therapie Systeme Ag Sistema de administracion transdermica que comprende buprenorfina.
US9895320B2 (en) 2012-09-28 2018-02-20 KM Transderm Ltd. Transdermal patch with different viscosity hydrocarbon oils in the drug layer and the adhesive layer
AU2013205080B2 (en) 2012-12-12 2016-07-07 Lts Lohmann Therapie-Systeme Ag Transdermal Delivery System
JP6559121B2 (ja) 2013-06-04 2019-08-14 エルテーエス ローマン テラピー−ジステーメ アーゲー 経皮送達システム

Also Published As

Publication number Publication date
JP6559121B2 (ja) 2019-08-14
AU2014276910B2 (en) 2017-03-09
BR112015029920A2 (pt) 2017-07-25
US20180092905A1 (en) 2018-04-05
HUE031662T2 (en) 2017-07-28
CA2914425A1 (en) 2014-12-11
ZA201509309B (en) 2017-11-29
GB201522307D0 (en) 2016-02-03
PE20160002A1 (es) 2016-01-23
KR102302505B1 (ko) 2021-09-15
JP2016520638A (ja) 2016-07-14
US20200237748A1 (en) 2020-07-30
EP2810646A1 (en) 2014-12-10
MA38698A1 (fr) 2017-02-28
PH12015502550A1 (en) 2016-02-22
AP2015008920A0 (en) 2015-12-31
DK2810646T3 (en) 2016-10-31
CN105377245B (zh) 2018-07-17
CR20150647A (es) 2016-02-19
LT2810646T (lt) 2016-10-25
EP3106153A1 (en) 2016-12-21
AU2014276910A1 (en) 2016-01-28
US20160008294A1 (en) 2016-01-14
EA201592246A1 (ru) 2016-05-31
MA38698B1 (fr) 2017-10-31
PL2810646T3 (pl) 2017-02-28
HK1204766A1 (zh) 2015-12-04
MX362614B (es) 2019-01-28
NI201500170A (es) 2016-08-05
WO2014195352A1 (en) 2014-12-11
EP2810646B1 (en) 2016-07-27
CN105377245A (zh) 2016-03-02
DE112014002664T5 (de) 2016-04-07
SI2810646T1 (sl) 2016-11-30
MX2015016123A (es) 2016-07-21
AR096521A1 (es) 2016-01-13
ES2599802T3 (es) 2017-02-03
GB2529789A (en) 2016-03-02
CY1118054T1 (el) 2017-06-28
US20170128384A1 (en) 2017-05-11
CA2914425C (en) 2019-09-17
HK1222135A1 (zh) 2017-06-23
PT2810646T (pt) 2016-10-05
TN2015000493A1 (en) 2017-04-06
US20160101100A1 (en) 2016-04-14
KR20160014064A (ko) 2016-02-05
SG11201509218SA (en) 2015-12-30
US20200316055A1 (en) 2020-10-08
US11529345B2 (en) 2022-12-20
TW201509416A (zh) 2015-03-16

Similar Documents

Publication Publication Date Title
CL2015003377A1 (es) Sistema de liberación transdérmico.
CR20150360A (es) Sistema de liberación transdérmica
CY1123712T1 (el) Διαδερμικο θεραπευτικο συστημα για την χορηγηση μιας δραστικης ουσιας
ES2543977T3 (es) Sistema terapéutico transdérmico para la administración del principio activo buprenorfina
WO2014160804A3 (en) Systems and methods using microneedles
CR20140321A (es) Sistema de administracion transdermica que contiene buprenofina
BR302013006823S1 (pt) Configuração aplicada em curativo médico
CL2015001882A1 (es) Sistema de entrega de fragancias
RU2016109449A (ru) Устройства для трансдермальной доставки дексмедетомидина и способы их применения
BR112016000350A8 (pt) métodos de tratamento de lesões inflamatórias da rosácea e usos de uma composição farmacêutica
DK2964088T3 (da) Vaginalt lægemiddeladministrations- og/eller diagnosesystem
PE20152016A1 (es) Toallas sanitarias femeninas gasas/vendoletes quirurgicos y para cuidar heridas y toallas para incontinencias con turmalina
AR095258A1 (es) Composiciones transdérmicas de metilfenidato con adhesivos a base de goma
AR070031A1 (es) Sistemas de administracion transdermicos de droga ketotifen y metodos para el tratamiento de enfermedades oftalmicas
EA201400628A1 (ru) Трансдермальная терапевтическая система для введения фентанила или его аналога
BR112017013273A2 (pt) emplastro em gel
ECSP14010605A (es) Sistema para la administración de fármacos
EP3065674A4 (en) Monolithic medical devices and methods of use
MX338901B (es) Parche con oclusion ajustable.
WO2016149077A3 (en) Fentanyl transdermal delivery system
ECSP16069947A (es) Formulaciones tópicas de heparina
PE20150022A1 (es) Dronedarona para uso en la leishmaniosis, formulaciones y asociaciones para uso en la leishmaniosis
ECSP14008829A (es) Sistema de administracion transdermica
IT201700036919A1 (it) Dispositivo medico per la rigenerazione tissulare da impiegare in Chirurgia rigenerativa
AR098771A1 (es) Un dispositivo para la administración transdérmica de rotigotina