MX2014009546A - Compuestos antivirales con una porcion heterotriciclica. - Google Patents
Compuestos antivirales con una porcion heterotriciclica.Info
- Publication number
- MX2014009546A MX2014009546A MX2014009546A MX2014009546A MX2014009546A MX 2014009546 A MX2014009546 A MX 2014009546A MX 2014009546 A MX2014009546 A MX 2014009546A MX 2014009546 A MX2014009546 A MX 2014009546A MX 2014009546 A MX2014009546 A MX 2014009546A
- Authority
- MX
- Mexico
- Prior art keywords
- heterotricycle
- moiety
- compounds
- antiviral compounds
- disclosed
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 230000000840 anti-viral effect Effects 0.000 title 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 208000006454 hepatitis Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN147KO2012 | 2012-02-10 | ||
| IN1017KO2012 | 2012-09-04 | ||
| PCT/IB2013/051077 WO2013118102A1 (en) | 2012-02-10 | 2013-02-09 | Antiviral compounds with a heterotricycle moiety |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2014009546A true MX2014009546A (es) | 2015-10-29 |
Family
ID=54259033
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014009546A MX2014009546A (es) | 2012-02-10 | 2013-02-09 | Compuestos antivirales con una porcion heterotriciclica. |
Country Status (14)
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102863428B (zh) | 2011-07-09 | 2014-12-24 | 广东东阳光药业有限公司 | 作为丙型肝炎病毒抑制剂的螺环化合物 |
| NZ628515A (en) | 2012-02-10 | 2016-06-24 | Lupin Ltd | Antiviral compounds with a dibenzooxaheterocycle moiety |
| US20150023913A1 (en) | 2013-07-02 | 2015-01-22 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| US9717712B2 (en) | 2013-07-02 | 2017-08-01 | Bristol-Myers Squibb Company | Combinations comprising tricyclohexadecahexaene derivatives for use in the treatment of hepatitis C virus |
| CN105530933B (zh) | 2013-07-17 | 2018-12-11 | 百时美施贵宝公司 | 用于治疗hcv的包含联苯衍生物的组合产品 |
| CN104725365B (zh) * | 2013-12-23 | 2019-02-26 | 南京圣和药业股份有限公司 | 丙型肝炎病毒抑制剂及其应用 |
| US10617675B2 (en) | 2015-08-06 | 2020-04-14 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| KR102794564B1 (ko) * | 2016-04-08 | 2025-04-15 | 듀폰스페셜티머터리얼스코리아 유한회사 | 유기 전계 발광 화합물 및 이를 포함하는 유기 전계 발광 소자 |
| US11208527B2 (en) | 2016-04-15 | 2021-12-28 | Beckman Coulter, Inc. | Photoactive macromolecules and uses thereof |
| EP3454862B1 (en) | 2016-05-10 | 2024-09-11 | C4 Therapeutics, Inc. | Spirocyclic degronimers for target protein degradation |
| EP3455219A4 (en) | 2016-05-10 | 2019-12-18 | C4 Therapeutics, Inc. | AMINE-RELATED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN REDUCTION |
| WO2017197055A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | Heterocyclic degronimers for target protein degradation |
| WO2017197046A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | C3-carbon linked glutarimide degronimers for target protein degradation |
| CN110769822A (zh) | 2017-06-20 | 2020-02-07 | C4医药公司 | 用于蛋白降解的n/o-连接的降解决定子和降解决定子体 |
| UY38705A (es) * | 2019-05-23 | 2020-12-31 | Irbm S P A | Inhibidores tricíclicos sustituidos con oxalamido del virus de hepatitis b |
| CN114605310B (zh) * | 2022-04-09 | 2024-05-07 | 都创(上海)医药科技股份有限公司 | 一种氮杂五元环并三元环羧酸酯衍生物及其盐的合成方法 |
Family Cites Families (87)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US5019369A (en) | 1984-10-22 | 1991-05-28 | Vestar, Inc. | Method of targeting tumors in humans |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| WO2004014313A2 (en) | 2002-08-12 | 2004-02-19 | Bristol-Myers Squibb Company | Combination pharmaceutical agents as inhibitors of hcv replication |
| JPWO2005012284A1 (ja) | 2003-07-31 | 2007-09-27 | 大正製薬株式会社 | ４，５−ジヒドロナフト［１，２−ｂ］チオフェン誘導体 |
| DK2243766T3 (en) | 2003-09-19 | 2015-10-12 | Janssen Pharmaceutica Nv | 4 - ((phenoxyalkyl) thio) -phenoxyeddikesyrer for use in the treatment of PPAR delta mediated conditions |
| EP1682528B1 (en) | 2003-11-07 | 2007-09-12 | F. Hoffmann-La Roche Ag | BENZO [b][1,4] DIOXEPINE DERIVATIVES |
| GB0421908D0 (en) | 2004-10-01 | 2004-11-03 | Angeletti P Ist Richerche Bio | New uses |
| GB0501964D0 (en) | 2005-01-31 | 2005-03-09 | Arrow Therapeutics Ltd | Chemical compounds |
| US8143288B2 (en) | 2005-06-06 | 2012-03-27 | Bristol-Myers Squibb Company | Inhibitors of HCV replication |
| DK1940786T3 (da) | 2005-09-16 | 2010-11-08 | Arrow Therapeutics Ltd | Biphenylderivater og deres anvendelse ved behandling af hepatitis C |
| EP1971597A2 (en) | 2005-12-12 | 2008-09-24 | Genelabs Technologies, Inc. | N-(5-membered heteroaromatic ring)-amido anti-viral compounds |
| KR20080075909A (ko) | 2005-12-12 | 2008-08-19 | 제네랩스 테크놀로지스, 인코포레이티드 | Ｎ-(6-원 방향족 환)-아미도 항-바이러스 화합물 |
| WO2007082554A1 (en) | 2006-01-23 | 2007-07-26 | Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa | Modulators of hcv replication |
| US8329159B2 (en) | 2006-08-11 | 2012-12-11 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US7759495B2 (en) | 2006-08-11 | 2010-07-20 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US7659270B2 (en) | 2006-08-11 | 2010-02-09 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| EA200970375A1 (ru) | 2006-10-13 | 2009-10-30 | Президио Фармасьютикалз, Инк. | Соединения и способы лечения вируса гепатита с |
| US7888464B2 (en) | 2006-11-16 | 2011-02-15 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US20100055071A1 (en) | 2006-11-21 | 2010-03-04 | Martin Robert Leivers | Anti-Viral Compounds |
| WO2008064218A2 (en) | 2006-11-21 | 2008-05-29 | Smithkline Beecham Corporation | Amido anti-viral compounds |
| US7521444B2 (en) | 2007-03-14 | 2009-04-21 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
| US7741347B2 (en) | 2007-05-17 | 2010-06-22 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| TW200906826A (en) | 2007-06-12 | 2009-02-16 | Genelabs Tech Inc | Anti-viral inhibitors and methods of use |
| JP5395068B2 (ja) | 2007-06-29 | 2014-01-22 | ギリアード サイエンシーズ， インコーポレイテッド | トール様受容体７の調節物質としてのプリン誘導体およびその使用 |
| US7728027B2 (en) | 2007-08-08 | 2010-06-01 | Bristol-Myers Squibb Company | Process for synthesizing compounds useful for treating hepatitis C |
| US8629171B2 (en) | 2007-08-08 | 2014-01-14 | Bristol-Myers Squibb Company | Crystalline form of methyl ((1S)-1-((25)-2-(5-(4'-(2-((25)-1((2S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt |
| WO2009034390A1 (en) | 2007-09-14 | 2009-03-19 | Arrow Therapeutics Limited | Heterocyclic derivatives and their use in treating hepatitis c |
| MX2010003916A (es) | 2007-10-10 | 2010-05-05 | Novartis Ag | Espiro-pirrolidinas y su uso contra infeccion por el virus de hepatitis c (hcv) y por el virus de inmunodeficiencia humana (vih). |
| MX2010008699A (es) | 2008-02-12 | 2010-08-30 | Bristol Myers Squibb Co | Derivados heterociclicos como inhibidores de virus de la hepatitis c. |
| BRPI0822335A2 (pt) | 2008-02-12 | 2019-09-24 | Bristol-Myers Squibb Company | inibidores do vírus da hepatite c |
| US7704992B2 (en) | 2008-02-13 | 2010-04-27 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| CN102007122B (zh) | 2008-02-13 | 2013-09-04 | 百时美施贵宝公司 | 作为丙型肝炎病毒抑制剂的咪唑基联苯基咪唑 |
| US8147818B2 (en) | 2008-02-13 | 2012-04-03 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| AP3076A (en) | 2008-04-23 | 2014-12-31 | Gilead Sciences Inc | Carba-nucleoside analogs for antiviral treatment |
| US8133884B2 (en) | 2008-05-06 | 2012-03-13 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
| US8198449B2 (en) | 2008-09-11 | 2012-06-12 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
| US20110217265A1 (en) | 2008-09-23 | 2011-09-08 | Glenn Jeffrey S | Screening for Inhibitors of HCV Amphipathic Helix (AH) Function |
| CA2750577A1 (en) | 2008-12-03 | 2010-06-10 | Presidio Pharmaceuticals, Inc. | Inhibitors of hcv ns5a |
| CN102348713B (zh) | 2009-02-10 | 2015-12-02 | 吉里德科学公司 | 用于抗病毒治疗的carba-核苷类似物 |
| TWI438200B (zh) | 2009-02-17 | 2014-05-21 | 必治妥美雅史谷比公司 | Ｃ型肝炎病毒抑制劑 |
| US8188132B2 (en) | 2009-02-17 | 2012-05-29 | Enanta Pharmaceuticals, Inc. | Linked dibenzimidazole derivatives |
| WO2010096462A1 (en) | 2009-02-17 | 2010-08-26 | Enanta Pharmaceuticals, Inc | Linked diimidazole derivatives |
| WO2010096777A1 (en) | 2009-02-23 | 2010-08-26 | Presidio Pharmaceuticals, Inc. | Inhibitors of hcv ns5a |
| US8101643B2 (en) | 2009-02-27 | 2012-01-24 | Enanta Pharmaceuticals, Inc. | Benzimidazole derivatives |
| MY169311A (en) | 2009-03-27 | 2019-03-21 | Merck Sharp & Dohme | Inhibitors of hepatitis c virus replication |
| EP2410841A4 (en) | 2009-03-27 | 2012-10-24 | Presidio Pharmaceuticals Inc | SUBSTITUTED BICYCLIC HCV INHIBITORS |
| MX2011010132A (es) | 2009-03-27 | 2011-10-14 | Presidio Pharmaceuticals Inc | Inhibidores de anillo fusionado de hepatitis c. |
| US20110237636A1 (en) | 2009-03-30 | 2011-09-29 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| TW201038559A (en) | 2009-04-09 | 2010-11-01 | Bristol Myers Squibb Co | Hepatitis C virus inhibitors |
| US8143414B2 (en) | 2009-04-13 | 2012-03-27 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| KR20180028070A (ko) | 2009-05-13 | 2018-03-15 | 길리애드 파마셋 엘엘씨 | 항바이러스 화합물 |
| US8937150B2 (en) | 2009-06-11 | 2015-01-20 | Abbvie Inc. | Anti-viral compounds |
| WO2010148006A1 (en) | 2009-06-16 | 2010-12-23 | Enanta Pharmaceuticals, Inc. | Hepatitis c virus inhibitors |
| AU2010280711A1 (en) | 2009-08-07 | 2012-02-09 | Janssen Sciences Ireland Uc | Phenyl ethynyl derivatives as hepatitis C virus inhibitors |
| EP2475256A4 (en) | 2009-09-11 | 2013-06-05 | Enanta Pharm Inc | HEPATITIS C-VIRUS HEMMER |
| EP2475254A4 (en) | 2009-09-11 | 2013-05-22 | Enanta Pharm Inc | HEPATITIS C-VIRUS HEMMER |
| US8415374B2 (en) | 2009-10-12 | 2013-04-09 | Bristol-Myers Squibb Company | Combinations of hepatitis C virus inhibitors |
| US20110269956A1 (en) | 2009-11-11 | 2011-11-03 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| US20110274648A1 (en) | 2009-11-11 | 2011-11-10 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| US20110281910A1 (en) | 2009-11-12 | 2011-11-17 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| EP2512480A4 (en) | 2009-12-14 | 2013-05-15 | Enanta Pharm Inc | HEPATITIS C-VIRUS HEMMER |
| US8377980B2 (en) | 2009-12-16 | 2013-02-19 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| CA2785488A1 (en) | 2009-12-22 | 2011-07-21 | Merck Sharp & Dohme Corp. | Fused tricyclic compounds and methods of use thereof for the treatment of viral diseases |
| CA2784036A1 (en) | 2009-12-24 | 2011-06-30 | Vertex Pharmaceuticals Incorporated | Analogues for the treatment or prevention of flavivirus infections |
| US8362020B2 (en) | 2009-12-30 | 2013-01-29 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US8933110B2 (en) | 2010-01-25 | 2015-01-13 | Enanta Pharmaceuticals, Inc. | Hepatitis C virus inhibitors |
| AR080433A1 (es) | 2010-03-02 | 2012-04-11 | Merck Sharp & Dohme | Derivados de benzofurancarboxamidas utiles para tratar o prevenir infecciones por vhc y composiciones farmaceuticas que los contienen. |
| WO2011106929A1 (en) | 2010-03-02 | 2011-09-09 | Merck Sharp & Dohme Corp. | Inhibitors of hepatitis c virus ns5b polymerase |
| EP2542074A4 (en) | 2010-03-04 | 2014-05-14 | Enanta Pharm Inc | PHARMACEUTICAL COMBINATION ACTIVE AGENTS AS HCV REPLICATION INHIBITORS |
| KR20130008040A (ko) | 2010-03-09 | 2013-01-21 | 머크 샤프 앤드 돔 코포레이션 | 융합된 트리시클릭 실릴 화합물 및 바이러스성 질환의 치료를 위한 그의 사용 방법 |
| WO2011127350A1 (en) | 2010-04-09 | 2011-10-13 | Enanta Pharmaceuticals, Inc. | Hepatitis c virus inhibitors |
| WO2011151651A1 (en) | 2010-06-03 | 2011-12-08 | Arrow Therapeutics Limited | Benzodiazepine compounds useful for the treatment of hepatitis c |
| WO2011151652A1 (en) | 2010-06-03 | 2011-12-08 | Arrow Therapeutics Limited | Benzodiazepine compounds useful for the treatment of hepatitis c |
| EP2575819A4 (en) | 2010-06-04 | 2013-11-27 | Enanta Pharm Inc | INHIBITORS OF HEPATITIS C VIRUS |
| AR081848A1 (es) | 2010-06-09 | 2012-10-24 | Presidio Pharmaceuticals Inc | Inhibidores de la proteina ns5a del vhc |
| CA2805440A1 (en) | 2010-07-26 | 2012-02-09 | Merck Sharp & Dohme Corp. | Substituted biphenylene compounds and methods of use thereof for the treatment of viral diseases |
| EP2601188B1 (en) | 2010-08-04 | 2017-10-18 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
| US8697704B2 (en) | 2010-08-12 | 2014-04-15 | Enanta Pharmaceuticals, Inc. | Hepatitis C virus inhibitors |
| US20120195857A1 (en) | 2010-08-12 | 2012-08-02 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| CA2808291A1 (en) | 2010-08-17 | 2012-02-23 | Vertex Pharmaceuticals Incorporated | Compounds and methods for the treatment or prevention of flaviviridae viral infections |
| CA2812699A1 (en) | 2010-09-24 | 2012-03-29 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
| BR112013007696A2 (pt) | 2010-09-29 | 2019-09-24 | Merck Sharp & Dohme | composto, composição farmacêutica, usos do referido composto e da referida composição |
| EP2621932A4 (en) | 2010-09-29 | 2014-03-26 | Merck Sharp & Dohme | TETRACYCLIC HETEROCYCLUS COMPOUNDS FOR THE TREATMENT OF HEPATITIS C VIRUS INFECTIONS |
| AU2011328980B2 (en) | 2010-11-17 | 2015-07-30 | Gilead Sciences, Inc. | Antiviral compounds |
| NZ628515A (en) | 2012-02-10 | 2016-06-24 | Lupin Ltd | Antiviral compounds with a dibenzooxaheterocycle moiety |
-
2013
- 2013-02-08 NZ NZ628515A patent/NZ628515A/en not_active IP Right Cessation
- 2013-02-08 SG SG11201404475TA patent/SG11201404475TA/en unknown
- 2013-02-08 AU AU2013217224A patent/AU2013217224B2/en not_active Expired - Fee Related
- 2013-02-08 WO PCT/IB2013/051062 patent/WO2013118097A1/en not_active Ceased
- 2013-02-08 IN IN1547MUN2014 patent/IN2014MN01547A/en unknown
- 2013-02-08 EP EP13715002.5A patent/EP2812326A1/en not_active Ceased
- 2013-02-08 US US14/375,534 patent/US9073943B2/en not_active Expired - Fee Related
- 2013-02-08 CA CA2862755A patent/CA2862755A1/en not_active Abandoned
- 2013-02-09 WO PCT/IB2013/051077 patent/WO2013118102A1/en not_active Ceased
- 2013-02-09 IN IN1548MUN2014 patent/IN2014MN01548A/en unknown
- 2013-02-09 CA CA2862330A patent/CA2862330A1/en not_active Abandoned
- 2013-02-09 US US14/375,530 patent/US9073942B2/en not_active Expired - Fee Related
- 2013-02-09 MX MX2014009546A patent/MX2014009546A/es unknown
- 2013-02-09 AU AU2013217229A patent/AU2013217229B2/en not_active Expired - Fee Related
- 2013-02-09 CN CN201380008883.4A patent/CN104136433B/zh not_active Expired - Fee Related
- 2013-02-09 SG SG11201404365SA patent/SG11201404365SA/en unknown
- 2013-02-09 KR KR20147023151A patent/KR20140129034A/ko not_active Withdrawn
- 2013-02-09 NZ NZ628445A patent/NZ628445A/en not_active IP Right Cessation
- 2013-02-09 JP JP2014556185A patent/JP6034883B2/ja not_active Expired - Fee Related
- 2013-02-09 BR BR112014019584A patent/BR112014019584A8/pt active Search and Examination
- 2013-02-09 EP EP13708912.4A patent/EP2812327A1/en not_active Withdrawn
-
2014
- 2014-07-25 ZA ZA2014/05490A patent/ZA201405490B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP6034883B2 (ja) | 2016-11-30 |
| AU2013217229B2 (en) | 2017-03-02 |
| NZ628515A (en) | 2016-06-24 |
| US9073942B2 (en) | 2015-07-07 |
| US9073943B2 (en) | 2015-07-07 |
| WO2013118102A1 (en) | 2013-08-15 |
| AU2013217224A1 (en) | 2014-08-21 |
| US20150010505A1 (en) | 2015-01-08 |
| SG11201404365SA (en) | 2014-10-30 |
| ZA201405490B (en) | 2015-10-28 |
| NZ628445A (en) | 2016-05-27 |
| WO2013118097A1 (en) | 2013-08-15 |
| CA2862755A1 (en) | 2013-08-15 |
| AU2013217224B2 (en) | 2017-04-06 |
| AU2013217229A1 (en) | 2014-08-21 |
| SG11201404475TA (en) | 2014-08-28 |
| CN104136433A (zh) | 2014-11-05 |
| CA2862330A1 (en) | 2013-08-15 |
| IN2014MN01548A (cg-RX-API-DMAC7.html) | 2015-05-08 |
| EP2812327A1 (en) | 2014-12-17 |
| KR20140129034A (ko) | 2014-11-06 |
| EP2812326A1 (en) | 2014-12-17 |
| IN2014MN01547A (cg-RX-API-DMAC7.html) | 2015-05-08 |
| CN104136433B (zh) | 2016-05-04 |
| BR112014019584A2 (cg-RX-API-DMAC7.html) | 2017-06-20 |
| JP2015510512A (ja) | 2015-04-09 |
| US20150010504A1 (en) | 2015-01-08 |
| BR112014019584A8 (pt) | 2017-07-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2014009546A (es) | Compuestos antivirales con una porcion heterotriciclica. | |
| NZ748966A (en) | Functionalized benzamide derivatives as antiviral agents against hbv infection | |
| MX2022013596A (es) | Compuestos de carbamoilpiridona policiclicos y su uso farmaceutico. | |
| EA026667B9 (ru) | Фармацевтическая композиция для лечения вируса гепатита с | |
| NZ703040A (en) | Macrocyclic inhibitors of flaviviridae viruses | |
| NZ703066A (en) | Macrocyclic inhibitors of flaviviridae viruses | |
| MD20140135A2 (ro) | Inhibitori macrociclici ai viruşilor din familia Flaviviridae | |
| NZ703064A (en) | Inhibitors of hepatitis c virus | |
| MX2013006475A (es) | Inhibidores macrociclicos de virus flaviviridae. | |
| MX2012008221A (es) | Inhibidores de virus flaviviridae. | |
| CL2011002830A1 (es) | Compuestos derivados de haloalquil heteroaril benzamidas; composicion farmaceutica uso de la composicion en el tratamiento de una infeccion viral, tal como el virus de la hepatitis b y c. | |
| MX2012008211A (es) | Inhibidores de virus flaviviridae. | |
| PH12019550113A1 (en) | Nucleotide hemi-sulfate salt for the treatment of hepatitis c virus | |
| NZ631726A (en) | Therapeutic compounds for the treatment of viral infections | |
| GEP20156263B (en) | Substituted azoles, anti-viral active ingredient, pharmaceutical composition, method for production and usage thereof | |
| IN2012DN01855A (cg-RX-API-DMAC7.html) | ||
| HK1211290A1 (en) | Heterocycle-substitued tetracyclic compounds and methods of use thereof for treatment of viral diseases | |
| WO2011160024A3 (en) | Compounds useful as antiviral agents, compositions, and methods of use | |
| PH12014500385A1 (en) | Benzofuran compounds for the treatment of hepatitis c virus infections | |
| WO2014116772A3 (en) | Squaric derivatives for the treatment of hepatitis c | |
| GB201008123D0 (en) | Novel compounds | |
| HK1198387A1 (zh) | 用作黃病毒科病毒抑制物之噻吩-2-羧酸衍生物 |