MX2014009546A - Compuestos antivirales con una porcion heterotriciclica. - Google Patents
Compuestos antivirales con una porcion heterotriciclica.Info
- Publication number
- MX2014009546A MX2014009546A MX2014009546A MX2014009546A MX2014009546A MX 2014009546 A MX2014009546 A MX 2014009546A MX 2014009546 A MX2014009546 A MX 2014009546A MX 2014009546 A MX2014009546 A MX 2014009546A MX 2014009546 A MX2014009546 A MX 2014009546A
- Authority
- MX
- Mexico
- Prior art keywords
- heterotricycle
- moiety
- compounds
- antiviral compounds
- disclosed
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Se describen compuestos de formula (I) para su uso como agentes antivíricos, en particular, como agentes contra el virus de la hepatitis C, donde A, B, U, R1-R7, m, n y q son como se describen en la presente. También se describen composiciones farmacéuticas y métodos para tratar o prevenir una infección vírica en un huésped utilizando estos compuestos, ya sean solos o combinados con otros principios farmacéuticamente activos. Además se describen métodos para preparar tales compuestos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN147KO2012 | 2012-02-10 | ||
IN1017KO2012 | 2012-09-04 | ||
PCT/IB2013/051077 WO2013118102A1 (en) | 2012-02-10 | 2013-02-09 | Antiviral compounds with a heterotricycle moiety |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2014009546A true MX2014009546A (es) | 2015-10-29 |
Family
ID=54259033
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014009546A MX2014009546A (es) | 2012-02-10 | 2013-02-09 | Compuestos antivirales con una porcion heterotriciclica. |
Country Status (14)
Country | Link |
---|---|
US (2) | US9073943B2 (es) |
EP (2) | EP2812326A1 (es) |
JP (1) | JP6034883B2 (es) |
KR (1) | KR20140129034A (es) |
CN (1) | CN104136433B (es) |
AU (2) | AU2013217224B2 (es) |
BR (1) | BR112014019584A8 (es) |
CA (2) | CA2862755A1 (es) |
IN (2) | IN2014MN01547A (es) |
MX (1) | MX2014009546A (es) |
NZ (2) | NZ628515A (es) |
SG (2) | SG11201404475TA (es) |
WO (2) | WO2013118097A1 (es) |
ZA (1) | ZA201405490B (es) |
Families Citing this family (13)
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JP2014520822A (ja) | 2011-07-09 | 2014-08-25 | スンシネ ルアケ プハルマ カンパニー リミテッド | C型肝炎ウイルス阻害剤としてのスピロ化合物 |
IN2014MN01547A (es) | 2012-02-10 | 2015-05-08 | Lupin Ltd | |
US9717712B2 (en) | 2013-07-02 | 2017-08-01 | Bristol-Myers Squibb Company | Combinations comprising tricyclohexadecahexaene derivatives for use in the treatment of hepatitis C virus |
US20150023913A1 (en) | 2013-07-02 | 2015-01-22 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
EP3021845A1 (en) | 2013-07-17 | 2016-05-25 | Bristol-Myers Squibb Company | Combinations comprising biphenyl derivatives for use in the treatment of hcv |
CN104725365B (zh) * | 2013-12-23 | 2019-02-26 | 南京圣和药业股份有限公司 | 丙型肝炎病毒抑制剂及其应用 |
US10617675B2 (en) | 2015-08-06 | 2020-04-14 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
KR20170115940A (ko) * | 2016-04-08 | 2017-10-18 | 롬엔드하스전자재료코리아유한회사 | 유기 전계 발광 화합물 및 이를 포함하는 유기 전계 발광 소자 |
EP3455218A4 (en) | 2016-05-10 | 2019-12-18 | C4 Therapeutics, Inc. | C3 CARBON-BASED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN REDUCTION |
CN109562107A (zh) | 2016-05-10 | 2019-04-02 | C4医药公司 | 用于靶蛋白降解的杂环降解决定子体 |
CN109562113A (zh) | 2016-05-10 | 2019-04-02 | C4医药公司 | 用于靶蛋白降解的螺环降解决定子体 |
UY38705A (es) * | 2019-05-23 | 2020-12-31 | Irbm S P A | Inhibidores tricíclicos sustituidos con oxalamido del virus de hepatitis b |
CN114605310B (zh) * | 2022-04-09 | 2024-05-07 | 都创(上海)医药科技股份有限公司 | 一种氮杂五元环并三元环羧酸酯衍生物及其盐的合成方法 |
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IN2014MN01547A (es) | 2012-02-10 | 2015-05-08 | Lupin Ltd |
-
2013
- 2013-02-08 IN IN1547MUN2014 patent/IN2014MN01547A/en unknown
- 2013-02-08 NZ NZ628515A patent/NZ628515A/en not_active IP Right Cessation
- 2013-02-08 US US14/375,534 patent/US9073943B2/en not_active Expired - Fee Related
- 2013-02-08 SG SG11201404475TA patent/SG11201404475TA/en unknown
- 2013-02-08 CA CA2862755A patent/CA2862755A1/en not_active Abandoned
- 2013-02-08 EP EP13715002.5A patent/EP2812326A1/en not_active Ceased
- 2013-02-08 WO PCT/IB2013/051062 patent/WO2013118097A1/en active Application Filing
- 2013-02-08 AU AU2013217224A patent/AU2013217224B2/en not_active Expired - Fee Related
- 2013-02-09 SG SG11201404365SA patent/SG11201404365SA/en unknown
- 2013-02-09 CN CN201380008883.4A patent/CN104136433B/zh not_active Expired - Fee Related
- 2013-02-09 NZ NZ628445A patent/NZ628445A/en not_active IP Right Cessation
- 2013-02-09 US US14/375,530 patent/US9073942B2/en not_active Expired - Fee Related
- 2013-02-09 CA CA2862330A patent/CA2862330A1/en not_active Abandoned
- 2013-02-09 IN IN1548MUN2014 patent/IN2014MN01548A/en unknown
- 2013-02-09 WO PCT/IB2013/051077 patent/WO2013118102A1/en active Application Filing
- 2013-02-09 JP JP2014556185A patent/JP6034883B2/ja not_active Expired - Fee Related
- 2013-02-09 KR KR20147023151A patent/KR20140129034A/ko not_active Application Discontinuation
- 2013-02-09 AU AU2013217229A patent/AU2013217229B2/en not_active Expired - Fee Related
- 2013-02-09 BR BR112014019584A patent/BR112014019584A8/pt active Search and Examination
- 2013-02-09 EP EP13708912.4A patent/EP2812327A1/en not_active Withdrawn
- 2013-02-09 MX MX2014009546A patent/MX2014009546A/es unknown
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2014
- 2014-07-25 ZA ZA2014/05490A patent/ZA201405490B/en unknown
Also Published As
Publication number | Publication date |
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JP2015510512A (ja) | 2015-04-09 |
IN2014MN01548A (es) | 2015-05-08 |
US9073942B2 (en) | 2015-07-07 |
SG11201404365SA (en) | 2014-10-30 |
CA2862755A1 (en) | 2013-08-15 |
WO2013118102A1 (en) | 2013-08-15 |
NZ628515A (en) | 2016-06-24 |
AU2013217229A1 (en) | 2014-08-21 |
BR112014019584A2 (es) | 2017-06-20 |
US9073943B2 (en) | 2015-07-07 |
CA2862330A1 (en) | 2013-08-15 |
KR20140129034A (ko) | 2014-11-06 |
SG11201404475TA (en) | 2014-08-28 |
AU2013217224A1 (en) | 2014-08-21 |
EP2812327A1 (en) | 2014-12-17 |
CN104136433B (zh) | 2016-05-04 |
EP2812326A1 (en) | 2014-12-17 |
WO2013118097A1 (en) | 2013-08-15 |
CN104136433A (zh) | 2014-11-05 |
ZA201405490B (en) | 2015-10-28 |
BR112014019584A8 (pt) | 2017-07-11 |
IN2014MN01547A (es) | 2015-05-08 |
AU2013217224B2 (en) | 2017-04-06 |
JP6034883B2 (ja) | 2016-11-30 |
NZ628445A (en) | 2016-05-27 |
US20150010504A1 (en) | 2015-01-08 |
AU2013217229B2 (en) | 2017-03-02 |
US20150010505A1 (en) | 2015-01-08 |
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