IN2014MN01547A - - Google Patents

Info

Publication number
IN2014MN01547A
IN2014MN01547A IN1547MUN2014A IN2014MN01547A IN 2014MN01547 A IN2014MN01547 A IN 2014MN01547A IN 1547MUN2014 A IN1547MUN2014 A IN 1547MUN2014A IN 2014MN01547 A IN2014MN01547 A IN 2014MN01547A
Authority
IN
India
Prior art keywords
compounds
disclosed
methods
agents
host
Prior art date
Application number
Inventor
Vidya Ramdas
Advait Arun Joshi
Moloy Manoj Banerjee
Amit Kumar Das
Deepak Sahebrao Walke
Venkata P Palle
Rajender Kumar Kamboj
Original Assignee
Lupin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lupin Ltd filed Critical Lupin Ltd
Priority to IN1547MUN2014 priority Critical patent/IN2014MN01547A/en
Publication of IN2014MN01547A publication Critical patent/IN2014MN01547A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Disclosed are compounds of formula (I) for use as antiviral agents particularly as anti hepatitis virus C agents wherein R R 6 and q are as described herein. Also disclosed are pharmaceutical compositions and methods of treating or preventing viral infection in a host by the use of these compounds either alone or in combination with other pharmaceutically active agents. Further disclosed are methods of preparing such compounds.(I).
IN1547MUN2014 2012-02-10 2013-02-08 IN2014MN01547A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IN1547MUN2014 IN2014MN01547A (en) 2012-02-10 2013-02-08

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN147KO2012 2012-02-10
IN1017KO2012 2012-09-04
IN1547MUN2014 IN2014MN01547A (en) 2012-02-10 2013-02-08
PCT/IB2013/051062 WO2013118097A1 (en) 2012-02-10 2013-02-08 Antiviral compounds with a dibenzooxaheterocycle moiety

Publications (1)

Publication Number Publication Date
IN2014MN01547A true IN2014MN01547A (en) 2015-05-08

Family

ID=54259033

Family Applications (2)

Application Number Title Priority Date Filing Date
IN1547MUN2014 IN2014MN01547A (en) 2012-02-10 2013-02-08
IN1548MUN2014 IN2014MN01548A (en) 2012-02-10 2013-02-09

Family Applications After (1)

Application Number Title Priority Date Filing Date
IN1548MUN2014 IN2014MN01548A (en) 2012-02-10 2013-02-09

Country Status (14)

Country Link
US (2) US9073943B2 (en)
EP (2) EP2812326A1 (en)
JP (1) JP6034883B2 (en)
KR (1) KR20140129034A (en)
CN (1) CN104136433B (en)
AU (2) AU2013217224B2 (en)
BR (1) BR112014019584A8 (en)
CA (2) CA2862755A1 (en)
IN (2) IN2014MN01547A (en)
MX (1) MX2014009546A (en)
NZ (2) NZ628515A (en)
SG (2) SG11201404475TA (en)
WO (2) WO2013118097A1 (en)
ZA (1) ZA201405490B (en)

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CA2841095A1 (en) 2011-07-09 2013-01-17 Sunshine Lake Pharma Co., Ltd. Spiro compounds as hepatitis c virus inhibitors
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JP2016527232A (en) 2013-07-17 2016-09-08 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ Combinations comprising biphenyl derivatives for use in the treatment of HCV
CN104725365B (en) * 2013-12-23 2019-02-26 南京圣和药业股份有限公司 Hepatitis C virus inhibitor and its application
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KR102794564B1 (en) * 2016-04-08 2025-04-15 듀폰스페셜티머터리얼스코리아 유한회사 Organic Electroluminescent Compound and Organic Electroluminescent Device Comprising the Same
WO2017180998A2 (en) 2016-04-15 2017-10-19 Beckman Coulter, Inc. Photoactive macromolecules and uses thereof
EP3454862B1 (en) 2016-05-10 2024-09-11 C4 Therapeutics, Inc. Spirocyclic degronimers for target protein degradation
CN109790143A (en) 2016-05-10 2019-05-21 C4医药公司 The C of amine connection for target protein degradation3Glutarimide degron body
WO2017197055A1 (en) 2016-05-10 2017-11-16 C4 Therapeutics, Inc. Heterocyclic degronimers for target protein degradation
CN109641874A (en) 2016-05-10 2019-04-16 C4医药公司 C for target protein degradation3The glutarimide degron body of carbon connection
CN110769822A (en) 2017-06-20 2020-02-07 C4医药公司 N/O-linked degron and degron bodies for protein degradation
UY38705A (en) * 2019-05-23 2020-12-31 Irbm S P A TRICYCLIC INHIBITORS SUBSTITUTED WITH HEPATITIS B VIRUS OXALAMIDE
CN114605310B (en) * 2022-04-09 2024-05-07 都创(上海)医药科技股份有限公司 Synthesis method of aza five-membered ring and three-membered ring carboxylic ester derivative and salt thereof

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Also Published As

Publication number Publication date
US9073943B2 (en) 2015-07-07
AU2013217229B2 (en) 2017-03-02
EP2812326A1 (en) 2014-12-17
AU2013217224A1 (en) 2014-08-21
US20150010504A1 (en) 2015-01-08
US20150010505A1 (en) 2015-01-08
EP2812327A1 (en) 2014-12-17
NZ628445A (en) 2016-05-27
CA2862330A1 (en) 2013-08-15
CN104136433B (en) 2016-05-04
NZ628515A (en) 2016-06-24
US9073942B2 (en) 2015-07-07
CN104136433A (en) 2014-11-05
WO2013118102A1 (en) 2013-08-15
JP2015510512A (en) 2015-04-09
AU2013217229A1 (en) 2014-08-21
KR20140129034A (en) 2014-11-06
MX2014009546A (en) 2015-10-29
SG11201404365SA (en) 2014-10-30
CA2862755A1 (en) 2013-08-15
AU2013217224B2 (en) 2017-04-06
BR112014019584A8 (en) 2017-07-11
IN2014MN01548A (en) 2015-05-08
JP6034883B2 (en) 2016-11-30
BR112014019584A2 (en) 2017-06-20
SG11201404475TA (en) 2014-08-28
WO2013118097A1 (en) 2013-08-15
ZA201405490B (en) 2015-10-28

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