MX2014008686A - Nuevas formas y sales de un inhibidor de aromatasa o sintasa de aldosterona de dihidro-pirrolo- [1,2-,c] -imidazolilo. - Google Patents

Nuevas formas y sales de un inhibidor de aromatasa o sintasa de aldosterona de dihidro-pirrolo- [1,2-,c] -imidazolilo.

Info

Publication number
MX2014008686A
MX2014008686A MX2014008686A MX2014008686A MX2014008686A MX 2014008686 A MX2014008686 A MX 2014008686A MX 2014008686 A MX2014008686 A MX 2014008686A MX 2014008686 A MX2014008686 A MX 2014008686A MX 2014008686 A MX2014008686 A MX 2014008686A
Authority
MX
Mexico
Prior art keywords
salt
phosphate salt
crystalline form
powder diffraction
benzonitrile
Prior art date
Application number
MX2014008686A
Other languages
English (en)
Spanish (es)
Inventor
Paul Sutton
Eric Loeser
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47604250&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2014008686(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2014008686A publication Critical patent/MX2014008686A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MX2014008686A 2012-01-17 2013-01-15 Nuevas formas y sales de un inhibidor de aromatasa o sintasa de aldosterona de dihidro-pirrolo- [1,2-,c] -imidazolilo. MX2014008686A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261587280P 2012-01-17 2012-01-17
PCT/US2013/021521 WO2013109514A1 (en) 2012-01-17 2013-01-15 New forms and salts of a dihydropyrrolo[1,2-c]imidazolyl aldosterone synthase or aromatase inhibitor

Publications (1)

Publication Number Publication Date
MX2014008686A true MX2014008686A (es) 2014-08-27

Family

ID=47604250

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014008686A MX2014008686A (es) 2012-01-17 2013-01-15 Nuevas formas y sales de un inhibidor de aromatasa o sintasa de aldosterona de dihidro-pirrolo- [1,2-,c] -imidazolilo.

Country Status (40)

Country Link
US (2) US9334276B2 (env)
EP (1) EP2804863B1 (env)
JP (1) JP5749410B2 (env)
KR (2) KR20140093726A (env)
CN (1) CN104039793B (env)
AP (1) AP2014007762A0 (env)
AR (1) AR089728A1 (env)
AU (1) AU2013209952B2 (env)
BR (1) BR112014017260A8 (env)
CA (1) CA2863339C (env)
CL (1) CL2014001863A1 (env)
CO (1) CO7000775A2 (env)
CR (1) CR20140345A (env)
CU (1) CU20140086A7 (env)
CY (1) CY1117914T1 (env)
DK (1) DK2804863T3 (env)
EA (1) EA026232B1 (env)
ES (1) ES2564143T3 (env)
GT (1) GT201400155A (env)
HR (1) HRP20160178T1 (env)
HU (1) HUE026984T2 (env)
IL (1) IL233541B (env)
IN (1) IN2014DN06781A (env)
JO (1) JO3137B1 (env)
MA (1) MA35858B1 (env)
MX (1) MX2014008686A (env)
NZ (1) NZ626277A (env)
PE (1) PE20142358A1 (env)
PH (1) PH12014501638A1 (env)
PL (1) PL2804863T3 (env)
RS (1) RS54589B1 (env)
SG (1) SG11201404061YA (env)
SI (1) SI2804863T1 (env)
SM (1) SMT201600083B (env)
TN (1) TN2014000256A1 (env)
TW (1) TWI609869B (env)
UA (1) UA114803C2 (env)
UY (1) UY34576A (env)
WO (1) WO2013109514A1 (env)
ZA (1) ZA201404314B (env)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011205290C1 (en) * 2010-01-14 2014-11-06 Recordati Ag Use of an adrenal hormone-modifying agent
EP2815749A1 (en) 2013-06-20 2014-12-24 IP Gesellschaft für Management mbH Solid form of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione having specified X-ray diffraction pattern
SI3166596T1 (sl) * 2014-07-07 2018-10-30 Novartis Ag Farmacevtske odmerne oblike
HUE054248T2 (hu) 2015-01-29 2021-08-30 Recordati Ag Eljárás kondenzált imidazo-származékok elõállítására
US20160287565A1 (en) * 2015-04-06 2016-10-06 Millendo Therapeutics, Inc. Combination therapy for treating disorders associated with excess cortisol production
EP3532056A1 (en) * 2016-10-27 2019-09-04 Damian Pharma AG Aldosterone synthase inhibitor
WO2018078049A1 (en) * 2016-10-27 2018-05-03 Damian Pharma Ag Aldosterone synthase inhibitor
WO2019211394A1 (en) 2018-05-03 2019-11-07 Damian Pharma Ag R-fadrozole for use in the treatment of aldostonerism

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1315449A (en) * 1918-11-15 1919-09-09 Frank B Yingling Shaper-feed.
US4617307A (en) 1984-06-20 1986-10-14 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridine derivatives as aromatase inhibitors
US5066656A (en) 1989-11-01 1991-11-19 Janssen Pharmaceutica N.V. Pharmacologically active (6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl)- and (5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl) substituted 1H-benzotriazole derivatives
MTP1076B (en) 1990-01-12 1991-09-30 Ciba Geigy Ag Hemihydrate
CA2127689A1 (en) 1992-01-27 1993-08-05 Marcel A. C. Janssen Pyrroloimidazolyl and imidazopyridinyl substituted 1h-benzimidazole derivatives as aromatase inhibitors
CA2505752A1 (en) 2002-11-18 2004-06-03 Novartis Ag Imidazo[1,5a]pyridine derivatives and methods for treating aldosterone mediated diseases
GT200600381A (es) * 2005-08-25 2007-03-28 Compuestos organicos
CN101578272A (zh) 2006-12-18 2009-11-11 诺瓦提斯公司 1-取代的咪唑衍生物和它们作为醛固酮合酶抑制剂的用途
US8575160B2 (en) 2009-11-30 2013-11-05 Novartis Ag Imidazole derivatives as aldosterone synthase inhibitors
AU2011205290C1 (en) * 2010-01-14 2014-11-06 Recordati Ag Use of an adrenal hormone-modifying agent

Also Published As

Publication number Publication date
HRP20160178T1 (hr) 2016-03-25
TN2014000256A1 (en) 2015-09-30
JO3137B1 (ar) 2017-09-20
JP5749410B2 (ja) 2015-07-15
PH12014501638B1 (en) 2014-10-13
NZ626277A (en) 2015-10-30
CO7000775A2 (es) 2014-07-21
CU20140086A7 (es) 2014-12-26
IL233541A0 (en) 2014-08-31
IL233541B (en) 2018-12-31
PL2804863T3 (pl) 2016-06-30
RS54589B1 (sr) 2016-08-31
PE20142358A1 (es) 2015-01-30
BR112014017260A2 (pt) 2017-06-13
CR20140345A (es) 2014-09-09
TWI609869B (zh) 2018-01-01
EP2804863B1 (en) 2015-12-02
ES2564143T8 (es) 2020-11-18
US20140364470A1 (en) 2014-12-11
AU2013209952A1 (en) 2014-07-24
EP2804863A1 (en) 2014-11-26
JP2015503627A (ja) 2015-02-02
UA114803C2 (uk) 2017-08-10
ES2564143T3 (es) 2016-03-18
AU2013209952B2 (en) 2016-09-01
CL2014001863A1 (es) 2014-11-07
UY34576A (es) 2013-09-02
CY1117914T1 (el) 2017-05-17
SG11201404061YA (en) 2014-08-28
EA026232B1 (ru) 2017-03-31
AR089728A1 (es) 2014-09-10
US20160176883A1 (en) 2016-06-23
CA2863339C (en) 2021-03-23
SI2804863T1 (sl) 2016-05-31
GT201400155A (es) 2017-09-28
IN2014DN06781A (env) 2015-05-22
DK2804863T3 (en) 2016-03-07
US9334276B2 (en) 2016-05-10
KR20140093726A (ko) 2014-07-28
EA201491374A1 (ru) 2014-12-30
PH12014501638A1 (en) 2014-10-13
ZA201404314B (en) 2015-08-26
CA2863339A1 (en) 2013-07-25
WO2013109514A1 (en) 2013-07-25
SMT201600083B (it) 2016-04-29
BR112014017260A8 (pt) 2017-07-04
CN104039793B (zh) 2017-05-10
HUE026984T2 (en) 2016-08-29
HK1198536A1 (en) 2015-05-15
AP2014007762A0 (en) 2014-07-31
KR20140141687A (ko) 2014-12-10
CN104039793A (zh) 2014-09-10
MA35858B1 (fr) 2014-12-01
TW201335161A (zh) 2013-09-01

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