MX2013001447A - Metodo de produccion y purificacion de una sialiltransferasa soluble activa. - Google Patents
Metodo de produccion y purificacion de una sialiltransferasa soluble activa.Info
- Publication number
- MX2013001447A MX2013001447A MX2013001447A MX2013001447A MX2013001447A MX 2013001447 A MX2013001447 A MX 2013001447A MX 2013001447 A MX2013001447 A MX 2013001447A MX 2013001447 A MX2013001447 A MX 2013001447A MX 2013001447 A MX2013001447 A MX 2013001447A
- Authority
- MX
- Mexico
- Prior art keywords
- sialyltransferase
- polypeptide
- purifying
- producing
- active soluble
- Prior art date
Links
- 102000003838 Sialyltransferases Human genes 0.000 title abstract 5
- 108090000141 Sialyltransferases Proteins 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 241000699802 Cricetulus griseus Species 0.000 abstract 1
- 102000004269 Granulocyte Colony-Stimulating Factor Human genes 0.000 abstract 1
- 108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 abstract 1
- OVRNDRQMDRJTHS-CBQIKETKSA-N N-Acetyl-D-Galactosamine Chemical compound CC(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@H](O)[C@@H]1O OVRNDRQMDRJTHS-CBQIKETKSA-N 0.000 abstract 1
- MBLBDJOUHNCFQT-UHFFFAOYSA-N N-acetyl-D-galactosamine Natural products CC(=O)NC(C=O)C(O)C(O)C(O)CO MBLBDJOUHNCFQT-UHFFFAOYSA-N 0.000 abstract 1
- 238000011210 chromatographic step Methods 0.000 abstract 1
- 230000013595 glycosylation Effects 0.000 abstract 1
- 238000006206 glycosylation reaction Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 210000001672 ovary Anatomy 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
- C12Y204/99003—Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase (2.4.99.3)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20100171626 EP2415779B1 (en) | 2010-08-02 | 2010-08-02 | Method of producing and purifying an active soluble sialyltransferase |
| PCT/EP2011/063291 WO2012016984A1 (en) | 2010-08-02 | 2011-08-02 | Method of producing and purifying an active soluble sialyltransferase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2013001447A true MX2013001447A (es) | 2013-11-20 |
Family
ID=42736163
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013001447A MX2013001447A (es) | 2010-08-02 | 2011-08-02 | Metodo de produccion y purificacion de una sialiltransferasa soluble activa. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9222081B2 (enExample) |
| EP (2) | EP2415779B1 (enExample) |
| JP (1) | JP5984267B2 (enExample) |
| CN (1) | CN103154017B (enExample) |
| CA (1) | CA2807397C (enExample) |
| ES (1) | ES2534936T3 (enExample) |
| MX (1) | MX2013001447A (enExample) |
| PT (1) | PT2415779E (enExample) |
| WO (1) | WO2012016984A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013075740A1 (en) | 2011-11-23 | 2013-05-30 | Sanofi | Antibody purification method |
| JP2016513245A (ja) * | 2013-02-06 | 2016-05-12 | エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ | タンパク質製剤の凝集体含有量を減少させる混合多官能金属親和性表面 |
| HUE038741T2 (hu) | 2013-05-06 | 2018-11-28 | Sanofi Sa | Folyamatos többlépéses eljárás antitestek tisztítására |
| KR20170132293A (ko) * | 2015-03-31 | 2017-12-01 | 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 | 글루타메이트 옥살로아세테이트 트랜스아미나제 1（ｇｏｔ１） 제제와 이의 제조방법 및 용도 |
| KR101667677B1 (ko) * | 2015-05-29 | 2016-10-19 | 한국생명공학연구원 | 재조합 ST6Gal1 단백질을 활성형으로 제조하는 방법 |
| EP3559250A1 (en) | 2016-12-21 | 2019-10-30 | H. Hoffnabb-La Roche Ag | Re-use of enzymes in in vitro glycoengineering of antibodies |
| AU2017381657B2 (en) | 2016-12-21 | 2020-07-23 | F. Hoffmann-La Roche Ag | Method for in vitro glycoengineering of antibodies |
| EP3678687B1 (en) | 2017-09-04 | 2022-08-17 | 89Bio Ltd. | Mutant fgf-21 peptide conjugates and uses thereof |
| WO2019063849A1 (en) * | 2017-12-20 | 2019-04-04 | Dsm Ip Assets B.V. | PURIFICATION OF A POLYPEPTIDE OF INTEREST |
| EP3546475A1 (en) | 2018-03-27 | 2019-10-02 | Sanofi | Full flow-through process for purifying recombinant proteins |
| KR102362777B1 (ko) * | 2018-03-27 | 2022-02-15 | 주식회사 녹십자 | 친화성 크로마토그래피 공정을 포함하는 백일해균 유래 단백질 수득 방법 |
| KR102140531B1 (ko) * | 2018-08-07 | 2020-08-04 | (주)휴온스 | Gly-Tβ4의 제조방법 |
| EP3613486B1 (de) * | 2018-08-24 | 2020-10-07 | UGA Biopharma GmbH | Verfahren und anlage zur reinigung von epo und/oder einem epo-derivat |
| CN113416243B (zh) * | 2021-08-23 | 2021-12-10 | 上海盛迪医药有限公司 | 一种纯化抗体的方法 |
| CN119912505A (zh) * | 2025-04-02 | 2025-05-02 | 浙江熙正霖生物科技有限公司 | 一种从发酵液中提纯唾液酸的方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5032519A (en) * | 1989-10-24 | 1991-07-16 | The Regents Of The Univ. Of California | Method for producing secretable glycosyltransferases and other Golgi processing enzymes |
| EP0737745A4 (en) | 1993-12-24 | 1999-06-16 | Rikagaku Kenkyusho | INNOVATIVE SYNTHETASE FOR SUGAR CHAINS AND METHOD FOR THEIR PRODUCTION |
| US6280989B1 (en) * | 1999-06-17 | 2001-08-28 | Dmitri Kapitonov | Sialyltransferases |
| ES2561985T3 (es) | 2001-10-10 | 2016-03-01 | Ratiopharm Gmbh | Remodelación y glicoconjugación de anticuerpos |
| CN1897812B (zh) * | 2003-12-03 | 2011-08-17 | 生物种属学股份公司 | 糖聚乙二醇化的粒细胞集落刺激因子 |
| WO2005121332A2 (en) | 2004-06-03 | 2005-12-22 | Neose Technologies, Inc. | Truncated st6galnaci polypeptides and nucleic acids |
| KR20080021590A (ko) | 2005-03-24 | 2008-03-07 | 네오스 테크놀로지스, 인크. | 가용성이고 활성인 진핵생물 글리코실트랜스퍼라제의원핵생물 유기체 내에서의 발현 |
| US20060246544A1 (en) | 2005-03-30 | 2006-11-02 | Neose Technologies,Inc. | Manufacturing process for the production of peptides grown in insect cell lines |
| WO2007056524A2 (en) | 2005-11-09 | 2007-05-18 | Neose Technologies, Inc. | St3gal-1/st6galnac-1 chimeras |
| JP2010505874A (ja) * | 2006-10-03 | 2010-02-25 | ノヴォ ノルディスク アー／エス | ポリペプチドコンジュゲートの精製方法 |
| US20080207487A1 (en) | 2006-11-02 | 2008-08-28 | Neose Technologies, Inc. | Manufacturing process for the production of polypeptides expressed in insect cell-lines |
-
2010
- 2010-08-02 EP EP20100171626 patent/EP2415779B1/en active Active
- 2010-08-02 PT PT101716264T patent/PT2415779E/pt unknown
- 2010-08-02 ES ES10171626.4T patent/ES2534936T3/es active Active
-
2011
- 2011-08-02 CN CN201180047627.7A patent/CN103154017B/zh not_active Expired - Fee Related
- 2011-08-02 EP EP11738247.3A patent/EP2601207B1/en active Active
- 2011-08-02 US US13/813,804 patent/US9222081B2/en active Active
- 2011-08-02 WO PCT/EP2011/063291 patent/WO2012016984A1/en not_active Ceased
- 2011-08-02 JP JP2013522234A patent/JP5984267B2/ja active Active
- 2011-08-02 MX MX2013001447A patent/MX2013001447A/es unknown
- 2011-08-02 CA CA2807397A patent/CA2807397C/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012016984A1 (en) | 2012-02-09 |
| CA2807397A1 (en) | 2012-02-09 |
| US20140057316A1 (en) | 2014-02-27 |
| EP2415779A1 (en) | 2012-02-08 |
| EP2415779B1 (en) | 2015-01-21 |
| CN103154017A (zh) | 2013-06-12 |
| PT2415779E (pt) | 2015-05-13 |
| ES2534936T3 (es) | 2015-04-30 |
| US9222081B2 (en) | 2015-12-29 |
| EP2601207A1 (en) | 2013-06-12 |
| JP5984267B2 (ja) | 2016-09-06 |
| EP2601207B1 (en) | 2016-12-28 |
| CN103154017B (zh) | 2016-02-03 |
| CA2807397C (en) | 2019-03-19 |
| JP2013535207A (ja) | 2013-09-12 |
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