PT2462098E - Processos para a preparação de derivados de ácido 1-(2- halobifenil-4-il)-ciclopropanocarboxílico - Google Patents
Processos para a preparação de derivados de ácido 1-(2- halobifenil-4-il)-ciclopropanocarboxílicoInfo
- Publication number
- PT2462098E PT2462098E PT107420838T PT10742083T PT2462098E PT 2462098 E PT2462098 E PT 2462098E PT 107420838 T PT107420838 T PT 107420838T PT 10742083 T PT10742083 T PT 10742083T PT 2462098 E PT2462098 E PT 2462098E
- Authority
- PT
- Portugal
- Prior art keywords
- halobiphenyl
- derivatives
- preparation
- cyclopropanecarboxylic acid
- formula
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
- B01J23/54—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals combined with metals, oxides or hydroxides provided for in groups B01J23/02 - B01J23/36
- B01J23/56—Platinum group metals
- B01J23/58—Platinum group metals with alkali- or alkaline earth metals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/14—Preparation of carboxylic acid nitriles by reaction of cyanides with halogen-containing compounds with replacement of halogen atoms by cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09167206 | 2009-08-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2462098E true PT2462098E (pt) | 2013-12-04 |
Family
ID=41479261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT107420838T PT2462098E (pt) | 2009-08-04 | 2010-07-22 | Processos para a preparação de derivados de ácido 1-(2- halobifenil-4-il)-ciclopropanocarboxílico |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9056818B2 (pt) |
| EP (1) | EP2462098B1 (pt) |
| JP (2) | JP5996428B2 (pt) |
| KR (1) | KR101737653B1 (pt) |
| CN (1) | CN102596879B (pt) |
| AU (1) | AU2010281069B2 (pt) |
| BR (1) | BR112012002500A2 (pt) |
| CA (1) | CA2769960C (pt) |
| DK (1) | DK2462098T3 (pt) |
| ES (1) | ES2437163T3 (pt) |
| HK (1) | HK1168588A1 (pt) |
| HR (1) | HRP20140032T1 (pt) |
| IL (1) | IL217886A (pt) |
| MX (1) | MX2012001411A (pt) |
| MY (1) | MY152980A (pt) |
| PT (1) | PT2462098E (pt) |
| RU (1) | RU2540076C2 (pt) |
| SG (1) | SG178239A1 (pt) |
| SI (1) | SI2462098T1 (pt) |
| UA (1) | UA106619C2 (pt) |
| WO (1) | WO2011015287A2 (pt) |
| ZA (1) | ZA201200821B (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2133322A1 (en) * | 2008-06-11 | 2009-12-16 | CHIESI FARMACEUTICI S.p.A. | Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid |
| CN102596879B (zh) * | 2009-08-04 | 2015-01-28 | 奇斯药制品公司 | 制备1-(2-卤代联苯-4-基)-环丙烷羧酸的衍生物的方法 |
| EP2552881A1 (en) | 2010-04-01 | 2013-02-06 | Chiesi Farmaceutici S.p.A. | Novel polymorphs and salts |
| US8975438B2 (en) * | 2011-07-13 | 2015-03-10 | Hoffmann-La Roche Inc. | Process for the preparation of cyclohexanecarboxylic acid derivatives |
| US9592210B2 (en) | 2011-12-22 | 2017-03-14 | Chiesi Farmaceutici S.P.A. | 1-phenylalkanecarboxylic acid derivatives for the treatment of cognitive impairment |
| CA2869418A1 (en) | 2012-04-04 | 2013-10-10 | Chiesi Farmaceutici S.P.A. | Derivatives of 1-(2-halo-biphenyl-4-yl)- alkanecarboxylic acids for the treatment of neurodegenerative diseases |
| EP2818460A1 (en) | 2013-06-24 | 2014-12-31 | ZaCh System S.p.A. | Cyclopropanation of substituted phenylacetonitriles or phenyl acetates |
| KR20160021772A (ko) * | 2013-06-24 | 2016-02-26 | 키에시 파르마슈티시 엣스. 피. 에이. | 1-(2-플루오로［1,1′-비페닐］-4-일)-시클로프로판카복실산의 유도체의 개선된 제조 방법 |
| WO2023034184A1 (en) | 2021-08-31 | 2023-03-09 | Cerespir Incorporated | Co-crystals |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1594833T3 (da) | 2003-02-21 | 2008-12-15 | Chiesi Farma Spa | 1-phenylalkancarboxylsyrederivater til behandling af neurodegenerative sygdomme |
| ITMI20030311A1 (it) * | 2003-02-21 | 2004-08-22 | Chiesi Farma Spa | Acidi 2-fenil-2-dialchil-acetici per il trattamento della malattia di alzheimer. |
| JP2005047842A (ja) * | 2003-07-31 | 2005-02-24 | Mitsubishi Chemicals Corp | 有機化合物の製造方法 |
| EP1650183A1 (en) * | 2004-10-21 | 2006-04-26 | Cellzome Ag | (Benzyloxy-biphenyl) acetic acids and derivatives thereof and their use in therapy |
| AU2006257670A1 (en) * | 2005-06-14 | 2006-12-21 | Merck Frosst Canada Ltd | Reversible inhibitors of monoamine oxidase A and B |
| PL2119703T3 (pl) * | 2007-01-15 | 2013-04-30 | Santen Pharmaceutical Co Ltd | Nowe pochodne indolu o aktywności hamującej kinazę-ßIκB |
| EP2133322A1 (en) | 2008-06-11 | 2009-12-16 | CHIESI FARMACEUTICI S.p.A. | Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid |
| CN102596879B (zh) * | 2009-08-04 | 2015-01-28 | 奇斯药制品公司 | 制备1-(2-卤代联苯-4-基)-环丙烷羧酸的衍生物的方法 |
-
2010
- 2010-07-22 CN CN201080034395.7A patent/CN102596879B/zh not_active Expired - Fee Related
- 2010-07-22 UA UAA201200649A patent/UA106619C2/uk unknown
- 2010-07-22 DK DK10742083.8T patent/DK2462098T3/da active
- 2010-07-22 BR BR112012002500A patent/BR112012002500A2/pt not_active IP Right Cessation
- 2010-07-22 KR KR1020127001858A patent/KR101737653B1/ko active IP Right Grant
- 2010-07-22 CA CA2769960A patent/CA2769960C/en not_active Expired - Fee Related
- 2010-07-22 SG SG2012007548A patent/SG178239A1/en unknown
- 2010-07-22 AU AU2010281069A patent/AU2010281069B2/en not_active Ceased
- 2010-07-22 WO PCT/EP2010/004481 patent/WO2011015287A2/en active Application Filing
- 2010-07-22 ES ES10742083.8T patent/ES2437163T3/es active Active
- 2010-07-22 MY MYPI2012000462 patent/MY152980A/en unknown
- 2010-07-22 JP JP2012523221A patent/JP5996428B2/ja active Active
- 2010-07-22 SI SI201030468T patent/SI2462098T1/sl unknown
- 2010-07-22 PT PT107420838T patent/PT2462098E/pt unknown
- 2010-07-22 RU RU2012104795/04A patent/RU2540076C2/ru active
- 2010-07-22 EP EP10742083.8A patent/EP2462098B1/en active Active
- 2010-07-22 MX MX2012001411A patent/MX2012001411A/es active IP Right Grant
- 2010-07-29 US US12/846,341 patent/US9056818B2/en active Active
-
2012
- 2012-02-02 IL IL217886A patent/IL217886A/en not_active IP Right Cessation
- 2012-02-02 ZA ZA2012/00821A patent/ZA201200821B/en unknown
- 2012-09-21 HK HK12109297.7A patent/HK1168588A1/xx not_active IP Right Cessation
-
2014
- 2014-01-13 HR HRP20140032AT patent/HRP20140032T1/hr unknown
-
2015
- 2015-02-25 JP JP2015034663A patent/JP6001112B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010281069A1 (en) | 2012-02-23 |
| JP2013501010A (ja) | 2013-01-10 |
| BR112012002500A2 (pt) | 2018-03-13 |
| MX2012001411A (es) | 2012-03-29 |
| CN102596879A (zh) | 2012-07-18 |
| SI2462098T1 (sl) | 2014-01-31 |
| JP5996428B2 (ja) | 2016-09-21 |
| US20110039934A1 (en) | 2011-02-17 |
| JP2015131824A (ja) | 2015-07-23 |
| RU2012104795A (ru) | 2013-09-10 |
| JP6001112B2 (ja) | 2016-10-05 |
| CN102596879B (zh) | 2015-01-28 |
| KR20120050977A (ko) | 2012-05-21 |
| ZA201200821B (en) | 2013-05-29 |
| HK1168588A1 (en) | 2013-01-04 |
| EP2462098B1 (en) | 2013-10-23 |
| AU2010281069B2 (en) | 2015-09-10 |
| IL217886A (en) | 2014-11-30 |
| CA2769960A1 (en) | 2011-02-10 |
| ES2437163T3 (es) | 2014-01-09 |
| SG178239A1 (en) | 2012-03-29 |
| UA106619C2 (uk) | 2014-09-25 |
| RU2540076C2 (ru) | 2015-01-27 |
| EP2462098A2 (en) | 2012-06-13 |
| WO2011015287A3 (en) | 2011-03-31 |
| US9056818B2 (en) | 2015-06-16 |
| MY152980A (en) | 2014-12-15 |
| CA2769960C (en) | 2017-04-18 |
| DK2462098T3 (da) | 2013-11-25 |
| HRP20140032T1 (hr) | 2014-02-14 |
| WO2011015287A2 (en) | 2011-02-10 |
| KR101737653B1 (ko) | 2017-05-18 |
| IL217886A0 (en) | 2012-03-29 |
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