MX2012007981A - Derivados de fumarato de acido graso y sus usos. - Google Patents

Derivados de fumarato de acido graso y sus usos.

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Publication number
MX2012007981A
MX2012007981A MX2012007981A MX2012007981A MX2012007981A MX 2012007981 A MX2012007981 A MX 2012007981A MX 2012007981 A MX2012007981 A MX 2012007981A MX 2012007981 A MX2012007981 A MX 2012007981A MX 2012007981 A MX2012007981 A MX 2012007981A
Authority
MX
Mexico
Prior art keywords
fatty acid
acid fumarate
fumarate derivatives
derivatives
effective amount
Prior art date
Application number
MX2012007981A
Other languages
English (en)
Other versions
MX337605B (es
Inventor
Michael R Jirousek
Jill C Milne
Jesse J Smith
Jean E Bemis
Chi B Vu
Original Assignee
Catabasis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44258993&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2012007981(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Catabasis Pharmaceuticals Inc filed Critical Catabasis Pharmaceuticals Inc
Publication of MX2012007981A publication Critical patent/MX2012007981A/es
Publication of MX337605B publication Critical patent/MX337605B/es

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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
    • C07C235/76—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid

Abstract

La invención se refiere a derivados de fumarato de ácido graso, a composiciones que comprenden una cantidad efectiva de un derivado de fumarato de ácido graso y a métodos para tratar o prevenir cáncer, un trastorno metabólico o trastorno neurodegenerativo que comprende la administración de una cantidad efectiva 'de un derivado de fumarato de ácido graso.
MX2012007981A 2010-01-08 2011-01-07 Derivados de fumarato de acido graso y sus usos. MX337605B (es)

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RU2012134069A (ru) 2014-02-20
KR20120123407A (ko) 2012-11-08
JP5771627B2 (ja) 2015-09-02
MY160249A (en) 2017-02-28
KR101828616B1 (ko) 2018-02-12
CA2786605A1 (en) 2011-07-14
US20160340294A1 (en) 2016-11-24
NI201200120A (es) 2013-06-12
IL244858A (en) 2016-12-29
US20150238618A1 (en) 2015-08-27
NZ601698A (en) 2015-04-24
ES2637266T3 (es) 2017-10-11
US8969354B2 (en) 2015-03-03
DK2521447T3 (en) 2017-09-18
AU2011204277B2 (en) 2015-12-24
CR20120413A (es) 2012-12-18
SG182414A1 (en) 2012-08-30
CN102821602B (zh) 2016-04-20
TWI508725B (zh) 2015-11-21
AU2011204277A1 (en) 2012-08-30
EP2521447A1 (en) 2012-11-14
IL244858A0 (en) 2016-05-31
TW201141471A (en) 2011-12-01
EP2521447A4 (en) 2014-04-30
CO6571913A2 (es) 2012-11-30
CN102821602A (zh) 2012-12-12
JP2013516486A (ja) 2013-05-13
US20110172240A1 (en) 2011-07-14
BR112012016879A2 (pt) 2015-09-01
EP2521447B1 (en) 2017-06-14
AR080357A1 (es) 2012-04-04
MX337605B (es) 2016-03-10
WO2011085211A1 (en) 2011-07-14
US20130065909A1 (en) 2013-03-14
US9289503B2 (en) 2016-03-22
CL2012001911A1 (es) 2012-10-26
ECSP12012097A (es) 2012-09-28

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