MX2012000275A - Antagonista de bomba de acido para el tratamiento de enfermedades involucradas en la motilidad gastrointestinal anormal. - Google Patents
Antagonista de bomba de acido para el tratamiento de enfermedades involucradas en la motilidad gastrointestinal anormal.Info
- Publication number
- MX2012000275A MX2012000275A MX2012000275A MX2012000275A MX2012000275A MX 2012000275 A MX2012000275 A MX 2012000275A MX 2012000275 A MX2012000275 A MX 2012000275A MX 2012000275 A MX2012000275 A MX 2012000275A MX 2012000275 A MX2012000275 A MX 2012000275A
- Authority
- MX
- Mexico
- Prior art keywords
- compound
- pharmaceutically acceptable
- acceptable salt
- acid pump
- treatment
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 4
- 239000002253 acid Substances 0.000 title abstract 3
- 230000002159 abnormal effect Effects 0.000 title abstract 2
- 230000002496 gastric effect Effects 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 7
- 150000003839 salts Chemical class 0.000 abstract 5
- 239000008194 pharmaceutical composition Substances 0.000 abstract 4
- 230000003042 antagnostic effect Effects 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nutrition Science (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009163182 | 2009-07-09 | ||
| JP2009188464 | 2009-08-17 | ||
| PCT/JP2010/061660 WO2011004882A1 (ja) | 2009-07-09 | 2010-07-09 | 消化管運動異常が関与する疾患を治療するためのアシッドポンプ拮抗剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2012000275A true MX2012000275A (es) | 2012-02-08 |
Family
ID=43429307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012000275A MX2012000275A (es) | 2009-07-09 | 2010-07-09 | Antagonista de bomba de acido para el tratamiento de enfermedades involucradas en la motilidad gastrointestinal anormal. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8648080B2 (https=) |
| EP (1) | EP2452680B1 (https=) |
| JP (4) | JP5802898B2 (https=) |
| KR (1) | KR101605063B1 (https=) |
| CN (2) | CN105919998B (https=) |
| BR (1) | BRPI1013288A2 (https=) |
| CA (1) | CA2765529C (https=) |
| ES (1) | ES2767251T3 (https=) |
| MX (1) | MX2012000275A (https=) |
| RU (1) | RU2586276C2 (https=) |
| WO (1) | WO2011004882A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3071206T3 (da) | 2013-11-22 | 2021-05-25 | CL BioSciences LLC | Gastrinantagonister (eg yf476, netazepid) til behandling og forebyggelse af osteoporose |
| CN105708812A (zh) * | 2014-12-02 | 2016-06-29 | 江苏柯菲平医药股份有限公司 | 一种5-（2-氟苯基）-n-甲基-1-（3-吡啶基磺酰基）-1h-吡咯-3-甲氨冻干粉针及其制备方法 |
| KR101684053B1 (ko) * | 2015-01-20 | 2016-12-08 | 씨제이헬스케어 주식회사 | 벤즈이미다졸 유도체의 신규 결정형 및 이의 제조방법 |
| MA41850A (fr) * | 2015-03-31 | 2018-02-06 | Takeda Pharmaceuticals Co | Nouvelles utilisations pharmaceutiques |
| MX374972B (es) | 2015-06-08 | 2025-03-06 | Hk Inno N Corp | Uso de derivados de bencimidazol para escape acido nocturno. |
| CN105078891B (zh) * | 2015-08-20 | 2018-04-24 | 寿光富康制药有限公司 | 一种tak-438脂质体及其制备方法和应用 |
| CN105168131B (zh) * | 2015-09-17 | 2018-04-24 | 寿光富康制药有限公司 | 一种tak-438纳米乳的制备方法 |
| CN106913859B (zh) * | 2015-12-25 | 2021-05-11 | 中美华世通生物医药科技(武汉)股份有限公司 | 药物组合物及制备方法 |
| CN105663096B (zh) * | 2016-01-25 | 2019-06-14 | 南京济群医药科技股份有限公司 | 一种沃诺拉赞口腔速溶膜剂及其制备方法 |
| KR101829706B1 (ko) | 2016-09-21 | 2018-02-19 | 씨제이헬스케어 주식회사 | 벤즈이미다졸 유도체의 산부가염 |
| JOP20190060A1 (ar) * | 2016-09-26 | 2019-03-26 | Chugai Pharmaceutical Co Ltd | مشتق بيرازولو بيريدين له تأثير مساعد لمستقبل glp-1 |
| CN112933091B (zh) * | 2020-09-07 | 2023-01-06 | 天地恒一制药股份有限公司 | 一种抗胃酸类疾病的药物组合物及应用 |
| AU2021364255B2 (en) * | 2020-10-23 | 2025-02-13 | Hk Inno.N Corporation | Orally disintegrating tablet comprising benzimidazole derivative compound and preparation method thereof |
| JP7566164B2 (ja) * | 2020-12-30 | 2024-10-11 | エイチケー イノ．エヌ コーポレーション | テゴプラザンおよび非ステロイド性抗炎症薬を含有する医薬組成物 |
| CN118355013A (zh) * | 2021-12-08 | 2024-07-16 | 制药基因科学株式会社 | 苯并咪唑衍生物化合物及其用途 |
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| WO2008095912A2 (en) | 2007-02-06 | 2008-08-14 | Nycomed Gmbh | Enantiopure pharmacologically active tricyclic benzimidazoles |
| US8933105B2 (en) | 2007-02-28 | 2015-01-13 | Takeda Pharmaceutical Company Limited | Pyrrole compounds |
| WO2008151927A2 (en) | 2007-06-15 | 2008-12-18 | Nycomed Gmbh | 6-n-substituted benz imidazole derivatives as acid pump antagonists |
| WO2009041705A2 (en) | 2007-09-28 | 2009-04-02 | Takeda Pharmaceutical Company Limited | 5-membered heterocyclic compounds as proton pump inhibitors |
| WO2009041447A1 (ja) | 2007-09-28 | 2009-04-02 | Takeda Pharmaceutical Company Limited | ５員複素環化合物 |
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2010
- 2010-07-09 EP EP10797193.9A patent/EP2452680B1/en active Active
- 2010-07-09 BR BRPI1013288A patent/BRPI1013288A2/pt not_active Application Discontinuation
- 2010-07-09 KR KR1020127002781A patent/KR101605063B1/ko active Active
- 2010-07-09 US US13/383,056 patent/US8648080B2/en active Active
- 2010-07-09 MX MX2012000275A patent/MX2012000275A/es active IP Right Grant
- 2010-07-09 WO PCT/JP2010/061660 patent/WO2011004882A1/ja not_active Ceased
- 2010-07-09 JP JP2011521969A patent/JP5802898B2/ja active Active
- 2010-07-09 CA CA2765529A patent/CA2765529C/en active Active
- 2010-07-09 RU RU2012104533/15A patent/RU2586276C2/ru active
- 2010-07-09 CN CN201610246787.9A patent/CN105919998B/zh active Active
- 2010-07-09 ES ES10797193T patent/ES2767251T3/es active Active
- 2010-07-09 CN CN2010800308648A patent/CN102470126A/zh active Pending
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2013
- 2013-04-30 JP JP2013094888A patent/JP5699309B2/ja active Active
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2014
- 2014-10-24 JP JP2014217434A patent/JP5978447B2/ja active Active
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2016
- 2016-06-23 JP JP2016125015A patent/JP6212765B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP5699309B2 (ja) | 2015-04-08 |
| CN105919998A (zh) | 2016-09-07 |
| RU2586276C2 (ru) | 2016-06-10 |
| JP2016166255A (ja) | 2016-09-15 |
| CN102470126A (zh) | 2012-05-23 |
| EP2452680B1 (en) | 2019-12-18 |
| JPWO2011004882A1 (ja) | 2012-12-20 |
| JP6212765B2 (ja) | 2017-10-18 |
| KR101605063B1 (ko) | 2016-03-21 |
| JP2013144719A (ja) | 2013-07-25 |
| CA2765529C (en) | 2017-02-07 |
| RU2012104533A (ru) | 2013-08-20 |
| JP5978447B2 (ja) | 2016-08-24 |
| EP2452680A1 (en) | 2012-05-16 |
| KR20120052269A (ko) | 2012-05-23 |
| HK1225608A1 (zh) | 2017-09-15 |
| JP2015038140A (ja) | 2015-02-26 |
| WO2011004882A1 (ja) | 2011-01-13 |
| CA2765529A1 (en) | 2011-01-13 |
| US8648080B2 (en) | 2014-02-11 |
| CN105919998B (zh) | 2021-08-24 |
| EP2452680A4 (en) | 2013-12-04 |
| BRPI1013288A2 (pt) | 2016-03-29 |
| US20120115820A1 (en) | 2012-05-10 |
| ES2767251T3 (es) | 2020-06-17 |
| JP5802898B2 (ja) | 2015-11-04 |
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