MX2009004561A - Derivados de pirazolilo con actividad analgesica y utiles en el tratamiento o profilaxis del dolor. - Google Patents
Derivados de pirazolilo con actividad analgesica y utiles en el tratamiento o profilaxis del dolor.Info
- Publication number
- MX2009004561A MX2009004561A MX2009004561A MX2009004561A MX2009004561A MX 2009004561 A MX2009004561 A MX 2009004561A MX 2009004561 A MX2009004561 A MX 2009004561A MX 2009004561 A MX2009004561 A MX 2009004561A MX 2009004561 A MX2009004561 A MX 2009004561A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- pain
- prophylaxis
- analgesic activity
- useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/16—Halogen atoms or nitro radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Esta invención se relaciona con el uso novedoso de derivados de pirazolilo y sales farmacéuticamente aceptables de estas, las cuales se ha encontrado que poseen actividad analgésica y por consiguiente son útiles en el tratamiento o profilaxis de padecimientos de dolor en el cuerpo humano o animal, por ejemplo, en la elaboración de medicamentos para el tratamiento o prevención en un animal de sangre caliente como el hombre.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86383906P | 2006-11-01 | 2006-11-01 | |
PCT/SE2007/000966 WO2008054291A1 (en) | 2006-11-01 | 2007-10-31 | Pyrazolyl derivatives with analgesic activity and therefore useful in the treatment or prophylaxis of pain. |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009004561A true MX2009004561A (es) | 2009-05-11 |
Family
ID=39344535
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009004561A MX2009004561A (es) | 2006-11-01 | 2007-10-31 | Derivados de pirazolilo con actividad analgesica y utiles en el tratamiento o profilaxis del dolor. |
Country Status (12)
Country | Link |
---|---|
US (1) | US20080108633A1 (es) |
EP (1) | EP2091540A4 (es) |
JP (1) | JP2010508345A (es) |
KR (1) | KR20090077063A (es) |
CN (1) | CN101534830A (es) |
AU (1) | AU2007314657A1 (es) |
BR (1) | BRPI0718003A2 (es) |
CA (1) | CA2668321A1 (es) |
MX (1) | MX2009004561A (es) |
RU (1) | RU2009112013A (es) |
TW (1) | TW200823196A (es) |
WO (1) | WO2008054291A1 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0104140D0 (sv) * | 2001-12-07 | 2001-12-07 | Astrazeneca Ab | Novel Compounds |
ES2375735T3 (es) * | 2005-02-04 | 2012-03-05 | Astrazeneca Ab | Derivados de pirazolilaminopiridina útiles como inhibidores de quinasas. |
AU2006215386B2 (en) * | 2005-02-16 | 2009-06-11 | Astrazeneca Ab | Chemical compounds |
BRPI0610184A2 (pt) * | 2005-05-16 | 2012-09-25 | Astrazeneca Ab | composto, sal farmaceuticamente aceitável de um composto, processo para preparar um composto ou um sal farmaceuticamente aceitável do mesmo, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, métodos para a inibição da atividade de trk, para o tratamento ou profilaxia de cáncer e para a produção de um efeito anti-proliferativo em um animal de sanque quente, e, composição farmacêutica |
EP2388259A1 (en) * | 2005-10-28 | 2011-11-23 | AstraZeneca AB | 4- (3-aminopyrazole) pyrimidine derivatives for use as tyrosine kinase inhibitors in the treatment of cancer |
WO2008129255A1 (en) * | 2007-04-18 | 2008-10-30 | Astrazeneca Ab | 5-aminopyrazol-3-yl-3h-imidazo [4,5-b] pyridine derivatives and their use for the treatment of cancer |
UA99459C2 (en) * | 2007-05-04 | 2012-08-27 | Астразенека Аб | 9-(pyrazol-3-yl)- 9h-purine-2-amine and 3-(pyraz0l-3-yl)-3h-imidazo[4,5-b]pyridin-5-amine derivatives and their use for the treatment of cancer |
CA2727073A1 (en) * | 2008-06-11 | 2009-12-17 | Astrazeneca Ab | Tricyclic 2,4-diamin0-l,3,5-triazine derivatives useful for the treatment of cancer and myeloproliferative disorders |
KR20110071098A (ko) * | 2008-09-30 | 2011-06-28 | 아스트라제네카 아베 | 복소환 jak 키나제 억제제 |
CN105979942B (zh) * | 2013-12-12 | 2018-12-07 | 比皮艾思药物研发有限公司 | 用于治疗或缓解疼痛的氨基磺酸酯衍生物 |
ES2706184T3 (es) | 2013-12-12 | 2019-03-27 | Bio Pharm Solutions Co Ltd | Compuesto derivado de sulfamato para su uso en la prevención o el tratamiento de la epilepsia |
KR101792998B1 (ko) * | 2013-12-12 | 2017-11-02 | (주)바이오팜솔루션즈 | 통증을 치료 또는 완화하기 위한 설파메이트 유도체 화합물 |
JP6427039B2 (ja) * | 2015-03-04 | 2018-11-21 | 株式会社浜松ファーマリサーチ | 非ヒト霊長類の二足歩行時の体動痛の評価方法 |
KR20220008828A (ko) * | 2019-05-15 | 2022-01-21 | 클라에스 툴린 | 동물에서 통증의 예방 및/또는 치료에 사용하기 위한 4-[5-[(rac)-1-[5-(3-클로로페닐)-3-이속사졸릴]에톡시]-4-메틸-4H-1,2,4-트리아졸-3-일]피리딘 |
US11987582B2 (en) * | 2021-01-27 | 2024-05-21 | Abion Inc. | Maleate salts of triazolopyrazine derivatives, compositions, methods of use, and processes of manufacturing the same |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1339680A1 (en) * | 2000-09-01 | 2003-09-03 | Glaxo Group Limited | Substituted oxindole derivatives as tyrosine kinase inhibitors |
MY141220A (en) * | 2003-11-17 | 2010-03-31 | Astrazeneca Ab | Pyrazole derivatives as inhibitors of receptor tyrosine kinases |
MXPA06014637A (es) * | 2004-06-25 | 2007-02-12 | Amgen Inc | Triazoles e indazoles condensados utiles en el tratamiento de enfermedades mediadas por citocinas y otras enfermedades. |
US20060069110A1 (en) * | 2004-09-27 | 2006-03-30 | Andersen Denise L | Substituted heterocyclic compounds and methods of use |
CN101208093A (zh) * | 2005-04-27 | 2008-06-25 | 阿斯利康(瑞典)有限公司 | 吡唑-嘧啶衍生物在治疗疼痛中的用途 |
BRPI0610184A2 (pt) * | 2005-05-16 | 2012-09-25 | Astrazeneca Ab | composto, sal farmaceuticamente aceitável de um composto, processo para preparar um composto ou um sal farmaceuticamente aceitável do mesmo, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, métodos para a inibição da atividade de trk, para o tratamento ou profilaxia de cáncer e para a produção de um efeito anti-proliferativo em um animal de sanque quente, e, composição farmacêutica |
-
2007
- 2007-10-24 TW TW096139911A patent/TW200823196A/zh unknown
- 2007-10-31 EP EP07835166A patent/EP2091540A4/en not_active Withdrawn
- 2007-10-31 KR KR1020097009099A patent/KR20090077063A/ko not_active Application Discontinuation
- 2007-10-31 CN CNA2007800408786A patent/CN101534830A/zh active Pending
- 2007-10-31 MX MX2009004561A patent/MX2009004561A/es unknown
- 2007-10-31 US US11/931,554 patent/US20080108633A1/en not_active Abandoned
- 2007-10-31 CA CA002668321A patent/CA2668321A1/en not_active Abandoned
- 2007-10-31 JP JP2009535235A patent/JP2010508345A/ja active Pending
- 2007-10-31 AU AU2007314657A patent/AU2007314657A1/en not_active Abandoned
- 2007-10-31 BR BRPI0718003-9A patent/BRPI0718003A2/pt not_active IP Right Cessation
- 2007-10-31 WO PCT/SE2007/000966 patent/WO2008054291A1/en active Application Filing
- 2007-10-31 RU RU2009112013/15A patent/RU2009112013A/ru not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
TW200823196A (en) | 2008-06-01 |
EP2091540A1 (en) | 2009-08-26 |
US20080108633A1 (en) | 2008-05-08 |
WO2008054291A1 (en) | 2008-05-08 |
AU2007314657A1 (en) | 2008-05-08 |
BRPI0718003A2 (pt) | 2013-11-19 |
KR20090077063A (ko) | 2009-07-14 |
CN101534830A (zh) | 2009-09-16 |
EP2091540A4 (en) | 2010-11-17 |
JP2010508345A (ja) | 2010-03-18 |
CA2668321A1 (en) | 2008-05-08 |
RU2009112013A (ru) | 2010-12-10 |
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