MX2011013164A - Forma de sosis farmaceutica para administracion oral de un inhibidor de la familia bcl-2. - Google Patents

Forma de sosis farmaceutica para administracion oral de un inhibidor de la familia bcl-2.

Info

Publication number
MX2011013164A
MX2011013164A MX2011013164A MX2011013164A MX2011013164A MX 2011013164 A MX2011013164 A MX 2011013164A MX 2011013164 A MX2011013164 A MX 2011013164A MX 2011013164 A MX2011013164 A MX 2011013164A MX 2011013164 A MX2011013164 A MX 2011013164A
Authority
MX
Mexico
Prior art keywords
dosage form
pharmaceutical dosage
bcl
oral administration
family inhibitor
Prior art date
Application number
MX2011013164A
Other languages
English (en)
Inventor
Bernd Liepold
Claudia Packhaeuser
Norbert Steiger
Drazen Kostelac
Martin Knobloch
Original Assignee
Abbott Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43063251&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2011013164(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Gmbh & Co Kg filed Critical Abbott Gmbh & Co Kg
Publication of MX2011013164A publication Critical patent/MX2011013164A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La invención se refiere a una forma de dosis farmacéutica que comprende un producto de dispersión sólida comprendiendo N-(4-(4-((2-(4-clorofenil)-5,5-dimetil-1-ciclohex-1-en-1-iI)metil )piperazin-1-il)-benzoil)-4-(((1R)-3-(morfolin-4-il)-1-((fenil-su lfanil)metil)propil)-amino)-3-((trifluorometil)sulfonil)bencensul fonamida o una sal, hidrato o solvato del mismo, por lo menos un polímero farmacéuticamente aceptable, y por lo menos un solubilizador farmacéuticamente aceptable. La invención además está dirigida a procedimientos para la preparación de la forma de dosis farmacéutica y al uso de la forma de dosis para tratar trastornos proliferativos.
MX2011013164A 2009-06-08 2010-06-08 Forma de sosis farmaceutica para administracion oral de un inhibidor de la familia bcl-2. MX2011013164A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18513009P 2009-06-08 2009-06-08
PCT/IB2010/001659 WO2010143074A2 (en) 2009-06-08 2010-06-08 Pharmaceutical dosage form for oral administration of a bcl-2 family inhibitor

Publications (1)

Publication Number Publication Date
MX2011013164A true MX2011013164A (es) 2012-04-20

Family

ID=43063251

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011013164A MX2011013164A (es) 2009-06-08 2010-06-08 Forma de sosis farmaceutica para administracion oral de un inhibidor de la familia bcl-2.

Country Status (38)

Country Link
US (5) US9642796B2 (es)
EP (3) EP2440177B1 (es)
JP (2) JP5872459B2 (es)
KR (2) KR101791404B1 (es)
CN (2) CN106074391A (es)
AR (2) AR077021A1 (es)
AU (1) AU2010258367B2 (es)
BR (2) BRPI1012831B1 (es)
CA (1) CA2763441C (es)
CL (1) CL2011003054A1 (es)
CO (1) CO6480964A2 (es)
CR (1) CR20170037A (es)
CY (1) CY1119663T1 (es)
DK (2) DK2440177T3 (es)
DO (2) DOP2011000375A (es)
EC (1) ECSP12011580A (es)
ES (2) ES2551860T3 (es)
HK (2) HK1169613A1 (es)
HR (2) HRP20151342T1 (es)
HU (2) HUE035727T2 (es)
IL (2) IL216494A (es)
LT (1) LT2982366T (es)
MX (1) MX2011013164A (es)
MY (1) MY159824A (es)
NO (1) NO2982366T3 (es)
NZ (1) NZ597241A (es)
PE (2) PE20160043A1 (es)
PL (2) PL2440177T3 (es)
PT (2) PT2982366T (es)
RU (2) RU2711359C2 (es)
SG (1) SG176264A1 (es)
SI (2) SI2982366T1 (es)
SM (1) SMT201500317B (es)
TW (2) TWI471321B (es)
UA (1) UA104471C2 (es)
UY (1) UY32695A (es)
WO (1) WO2010143074A2 (es)
ZA (1) ZA201108853B (es)

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Also Published As

Publication number Publication date
DK2982366T3 (en) 2018-01-02
PL2440177T3 (pl) 2016-03-31
JP2012529490A (ja) 2012-11-22
CN106074391A (zh) 2016-11-09
AR077021A1 (es) 2011-07-27
LT2982366T (lt) 2017-11-27
NZ597241A (en) 2014-01-31
RU2011154143A (ru) 2013-07-20
JP5872459B2 (ja) 2016-03-01
DOP2017000057A (es) 2017-04-16
BRPI1012831A2 (pt) 2018-03-06
TW201103925A (en) 2011-02-01
CL2011003054A1 (es) 2012-07-20
PT2440177E (pt) 2015-12-01
CR20170037A (es) 2017-04-17
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