MX2011007557A - Formas nuevas de bendamustina como base libre. - Google Patents

Formas nuevas de bendamustina como base libre.

Info

Publication number
MX2011007557A
MX2011007557A MX2011007557A MX2011007557A MX2011007557A MX 2011007557 A MX2011007557 A MX 2011007557A MX 2011007557 A MX2011007557 A MX 2011007557A MX 2011007557 A MX2011007557 A MX 2011007557A MX 2011007557 A MX2011007557 A MX 2011007557A
Authority
MX
Mexico
Prior art keywords
free base
bendamustine free
forms
novel forms
bendamustine
Prior art date
Application number
MX2011007557A
Other languages
English (en)
Spanish (es)
Inventor
Laurent D Courvoisier
Mark Eddleston
Curtis R Haltiwanger
Robert E Mckean
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42008533&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2011007557(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cephalon Inc filed Critical Cephalon Inc
Publication of MX2011007557A publication Critical patent/MX2011007557A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
MX2011007557A 2009-01-15 2010-01-14 Formas nuevas de bendamustina como base libre. MX2011007557A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14484309P 2009-01-15 2009-01-15
PCT/US2010/020992 WO2010083276A1 (en) 2009-01-15 2010-01-14 Novel forms of bendamustine free base

Publications (1)

Publication Number Publication Date
MX2011007557A true MX2011007557A (es) 2011-08-12

Family

ID=42008533

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011007557A MX2011007557A (es) 2009-01-15 2010-01-14 Formas nuevas de bendamustina como base libre.

Country Status (16)

Country Link
US (1) US8076366B2 (cg-RX-API-DMAC7.html)
EP (1) EP2387400A1 (cg-RX-API-DMAC7.html)
JP (1) JP2012515210A (cg-RX-API-DMAC7.html)
KR (1) KR20110110293A (cg-RX-API-DMAC7.html)
CN (2) CN102281877B (cg-RX-API-DMAC7.html)
AU (2) AU2010204765A1 (cg-RX-API-DMAC7.html)
BR (1) BRPI1004922A2 (cg-RX-API-DMAC7.html)
CA (1) CA2749101A1 (cg-RX-API-DMAC7.html)
EA (1) EA020767B1 (cg-RX-API-DMAC7.html)
IL (1) IL213725A0 (cg-RX-API-DMAC7.html)
MX (1) MX2011007557A (cg-RX-API-DMAC7.html)
NZ (1) NZ594010A (cg-RX-API-DMAC7.html)
SG (1) SG172810A1 (cg-RX-API-DMAC7.html)
UA (1) UA109109C2 (cg-RX-API-DMAC7.html)
WO (1) WO2010083276A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201105099B (cg-RX-API-DMAC7.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9376394B2 (en) * 2009-12-23 2016-06-28 Dr. Reddy's Laboratories Ltd. Preparation of bendamustine and its salts
EP3895694A1 (en) 2010-01-28 2021-10-20 Eagle Pharmaceuticals, Inc. Formulations of bendamustine
WO2012176214A2 (en) * 2011-06-20 2012-12-27 Hetero Research Foundation Process for bendamustine hydrochloride
RS58744B1 (sr) 2012-03-20 2019-06-28 Eagle Pharmaceuticals Inc Tečna kompozicija za upotrebu u postupku lečenja stanja koja reaguju na bendamustin kod pacijenata kojima su potrebne smanjene zapremine za davanje
DK2827862T3 (da) 2012-03-20 2024-02-12 Eagle Pharmaceuticals Inc Formuleringer af bendamustin
US20230241218A1 (en) * 2012-07-10 2023-08-03 Eagle Pharmaceuticals, Inc. Formulations of bendamustine
MX362032B (es) 2013-03-12 2019-01-04 Cephalon Inc Formulaciones nanoparticuladas y macroparticuladas.
EP2988655B1 (en) 2013-04-26 2023-04-12 Genentech, Inc. Contour integration perimetry vision test
US20240148696A1 (en) 2022-10-25 2024-05-09 Softkemo Pharma Inc. Lyophilized bendamustine-cyclodextrin composition

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DE293808C (cg-RX-API-DMAC7.html)
DE159877C (cg-RX-API-DMAC7.html)
DE80967C (cg-RX-API-DMAC7.html)
DD159289A1 (de) 1981-06-01 1983-03-02 Uwe Olthoff Verfahren zur herstellung stabiler injektionsloesungen von n-lostverbindungen
DD159877A1 (de) * 1981-06-12 1983-04-13 Wolfgang Krueger Verfahren zur herstellung von 4-[1-methyl-5-bis(2-chloraethyl)amino-benzimidazolyl-2]-buttersaeure
US5204335A (en) * 1986-10-31 1993-04-20 Asta Pharma Aktiengesellschaft Ifosfamide lyophilisate and process for its preparation
US5227373A (en) * 1991-10-23 1993-07-13 Bristol-Myers Squibb Co. Lyophilized ifosfamide compositions
DK0752248T3 (da) * 1992-11-13 2000-11-13 Idec Pharma Corp Terapeutisk anvendelse af kimæriske og radioaktivt mærkede antistoffer mod humant B-lymfocytbegrænset differentieringsantig
US5595721A (en) * 1993-09-16 1997-01-21 Coulter Pharmaceutical, Inc. Radioimmunotherapy of lymphoma using anti-CD20
PT725642E (pt) * 1993-10-27 2000-05-31 Upjohn Co Prostaglandina e 1 estabilizada
US5561121A (en) 1993-11-09 1996-10-01 American Cyanamid Company Stable lyophilized thiotepa composition
US5955504A (en) 1995-03-13 1999-09-21 Loma Linda University Medical Center Colorectal chemoprotective composition and method of preventing colorectal cancer
DE19529057B4 (de) * 1995-08-08 2007-12-13 Baxter Healthcare S.A. Ifosfamid-Lyophilisat-Zubereitungen
US6077850A (en) * 1997-04-21 2000-06-20 G.D. Searle & Co. Substituted benzopyran analogs for the treatment of inflammation
US20040072889A1 (en) * 1997-04-21 2004-04-15 Pharmacia Corporation Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
US6034256A (en) * 1997-04-21 2000-03-07 G.D. Searle & Co. Substituted benzopyran derivatives for the treatment of inflammation
ATE315392T1 (de) * 1998-07-09 2006-02-15 Francis A Nardella Zusammensetzungen zur behandlung chronischer lymphatischer leukämie
US5972912A (en) * 1998-12-17 1999-10-26 S.P. Pharmaceuticals Method for lyophilizing ifosfamide
US6569402B1 (en) * 1998-12-18 2003-05-27 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals
US6380210B1 (en) * 1999-04-02 2002-04-30 Neurogen Corporation Heteroaryl fused aminoalkyl-imidazole derivatives: selective modulators of GABAa receptors
US6545034B1 (en) * 1999-07-23 2003-04-08 The Regents Of The University Of California Use of etodolac for the treatment of chronic lymphocytic leukemia
DE10016077A1 (de) 2000-03-31 2001-12-13 Cellcontrol Biomedical Lab Gmb Verfahren und Vorrichtung zum automatischen Nachweisen einer Wirkung eines zellbeeinflussenden Mittels auf lebende Zellen
US20040152672A1 (en) * 2000-08-09 2004-08-05 Carson Dennis A. Indole compounds useful for the treatment of cancer
KR20040025880A (ko) * 2000-12-11 2004-03-26 다케다 야쿠힌 고교 가부시키가이샤 수용해성이 개선된 의약 조성물
EP1350793A1 (en) * 2000-12-11 2003-10-08 Takeda Chemical Industries, Ltd. Medicinal compositions having improved absorbability
EP1435877B1 (de) * 2001-10-15 2009-04-15 Hemoteq AG Beschichtung von stents zur verhinderung von restenose
US6613927B1 (en) 2002-02-08 2003-09-02 American Pharmaceutical Partners, Inc. Sterile lyophilized ifosfamide and associated methods
DE10306724A1 (de) 2002-02-28 2003-09-18 G O T Therapeutics Gmbh Vesikuläre Verkapselung von Bendamustin
ATE389183T1 (de) 2002-03-22 2008-03-15 Univ Muenchen L Maximilians Zytokapazität-verfahren
EP1495124A2 (en) 2002-04-17 2005-01-12 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Smac-peptides as therapeutics against cancer and autoimmune diseases
EP1354952A1 (en) 2002-04-17 2003-10-22 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Smac-peptides as therapeutics against cancer and autoimmune diseases
MXPA04011111A (es) 2002-05-09 2005-07-14 Hemoteq Gmbh Productos medicos que comprenden un revestimiento hemocompatible, produccion y uso de los mismos.
WO2004012769A1 (en) * 2002-08-02 2004-02-12 The Regents Of The University Of California Therapeutic inhibitionof protein kinases in cancer cells
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CN102177140B (zh) * 2008-10-08 2016-01-27 赛福伦公司 用于制备苯达莫司汀的方法

Also Published As

Publication number Publication date
KR20110110293A (ko) 2011-10-06
BRPI1004922A2 (pt) 2019-09-24
NZ594010A (en) 2013-08-30
ZA201105099B (en) 2012-03-28
EA020767B1 (ru) 2015-01-30
EA201170934A1 (ru) 2011-12-30
CA2749101A1 (en) 2010-07-22
CN102281877A (zh) 2011-12-14
CN103554030A (zh) 2014-02-05
AU2016204902A1 (en) 2016-08-04
SG172810A1 (en) 2011-08-29
EP2387400A1 (en) 2011-11-23
UA109109C2 (uk) 2015-07-27
IL213725A0 (en) 2011-07-31
US8076366B2 (en) 2011-12-13
CN102281877B (zh) 2014-07-23
WO2010083276A1 (en) 2010-07-22
JP2012515210A (ja) 2012-07-05
AU2010204765A1 (en) 2011-07-28
US20100210701A1 (en) 2010-08-19

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