MX2009011275A - Una composicion de microesferas biodegradables adecuadas para la liberacion controlada de peptido de control de la glucosa y formulacion de la misma. - Google Patents

Una composicion de microesferas biodegradables adecuadas para la liberacion controlada de peptido de control de la glucosa y formulacion de la misma.

Info

Publication number
MX2009011275A
MX2009011275A MX2009011275A MX2009011275A MX2009011275A MX 2009011275 A MX2009011275 A MX 2009011275A MX 2009011275 A MX2009011275 A MX 2009011275A MX 2009011275 A MX2009011275 A MX 2009011275A MX 2009011275 A MX2009011275 A MX 2009011275A
Authority
MX
Mexico
Prior art keywords
glucose
formulation
controlled release
composition suitable
microsphere composition
Prior art date
Application number
MX2009011275A
Other languages
English (en)
Inventor
Moohi Yoo
Tae Hyoung Kim
Soo Hyung Kang
Byong Moon Kim
Hyun Hee Kwak
Ghun Il Lee
Yong Man Park
Mi Kyung Son
Hi Chang Yang
Yoon Ji Kim
Sung Hee Lee
Original Assignee
Dong A Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong A Pharm Co Ltd filed Critical Dong A Pharm Co Ltd
Publication of MX2009011275A publication Critical patent/MX2009011275A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Se describen las microesferas biodegradables capaces de liberar un péptido regulador de la glucosa de una manera controlada, que comprende un portador polimérico biodegradable con el péptido regulador de la glucosa encapsulado en éste, y los métodos para la preparación de las mismas. Además, para asegurar la alta eficiencia de encapsulamiento y la alta estabilidad del fármaco encapsulado, las microesferas no muestran un efecto inicial rápida ni tampoco liberación incompleta, y permiten la liberación de orden cero de los fármacos en un periodo prolongado, mejorando de este modo el efecto terapéutico del fármaco.
MX2009011275A 2007-04-19 2008-04-18 Una composicion de microesferas biodegradables adecuadas para la liberacion controlada de peptido de control de la glucosa y formulacion de la misma. MX2009011275A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20070038467 2007-04-19
PCT/KR2008/002216 WO2008130158A1 (en) 2007-04-19 2008-04-18 A biodegradable microsphere composition suitable for the controlled release of glucose controlling peptide and formulation thereof

Publications (1)

Publication Number Publication Date
MX2009011275A true MX2009011275A (es) 2009-11-02

Family

ID=39875642

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009011275A MX2009011275A (es) 2007-04-19 2008-04-18 Una composicion de microesferas biodegradables adecuadas para la liberacion controlada de peptido de control de la glucosa y formulacion de la misma.

Country Status (14)

Country Link
US (1) US8282990B2 (es)
EP (1) EP2139458A4 (es)
JP (1) JP5302952B2 (es)
KR (2) KR101034888B1 (es)
CN (1) CN101657190B (es)
AU (1) AU2008241699B2 (es)
BR (1) BRPI0810140A2 (es)
CA (1) CA2683698C (es)
CO (1) CO6241098A2 (es)
IL (1) IL201523A0 (es)
MX (1) MX2009011275A (es)
NZ (1) NZ580700A (es)
RU (1) RU2422134C1 (es)
WO (1) WO2008130158A1 (es)

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Also Published As

Publication number Publication date
RU2422134C1 (ru) 2011-06-27
CN101657190B (zh) 2013-09-11
EP2139458A4 (en) 2013-01-23
JP2010524924A (ja) 2010-07-22
CA2683698A1 (en) 2008-10-30
CO6241098A2 (es) 2011-01-20
NZ580700A (en) 2012-01-12
AU2008241699B2 (en) 2011-02-03
IL201523A0 (en) 2010-05-31
CA2683698C (en) 2013-09-10
KR101034888B1 (ko) 2011-05-17
EP2139458A1 (en) 2010-01-06
AU2008241699A1 (en) 2008-10-30
WO2008130158A1 (en) 2008-10-30
US20100129459A1 (en) 2010-05-27
BRPI0810140A2 (pt) 2014-10-29
CN101657190A (zh) 2010-02-24
US8282990B2 (en) 2012-10-09
JP5302952B2 (ja) 2013-10-02
KR20110044192A (ko) 2011-04-28
KR20080094616A (ko) 2008-10-23
RU2009142608A (ru) 2011-05-27

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