MX2009006066A - Tratamiento de cerdos con el antigeno pcv. - Google Patents

Tratamiento de cerdos con el antigeno pcv.

Info

Publication number
MX2009006066A
MX2009006066A MX2009006066A MX2009006066A MX2009006066A MX 2009006066 A MX2009006066 A MX 2009006066A MX 2009006066 A MX2009006066 A MX 2009006066A MX 2009006066 A MX2009006066 A MX 2009006066A MX 2009006066 A MX2009006066 A MX 2009006066A
Authority
MX
Mexico
Prior art keywords
treatment
pigs
pcv2
pcv2 antigen
animals
Prior art date
Application number
MX2009006066A
Other languages
English (en)
Inventor
Knut Elbers
Axel Lischewski
Vicky Fachinger
Marion Kixmoeller
Francois-Xavier Orveillon
Isabelle Freiin Von Richthofen
Michael Piontkowski
Original Assignee
Boehringer Ingelheim Vetmed
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39537011&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009006066(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Vetmed filed Critical Boehringer Ingelheim Vetmed
Publication of MX2009006066A publication Critical patent/MX2009006066A/es

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/10011Circoviridae
    • C12N2750/10034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a un método para el tratamiento o profilaxis de una infección por PCV2 o para la reducción de los síntomas clínicos producidos por o asociados con una infección por PCV2 en animales a) que tienen anticuerpos anti-PCV2 y/o b) que son lechones jóvenes de 1 a 22 días de edad, que comprende la etapa de administrar una cantidad eficaz de un antígeno PCV2 al animal que necesite el tratamiento. Preferiblemente, los animales son cerdos o lechones jóvenes.
MX2009006066A 2006-12-15 2007-12-14 Tratamiento de cerdos con el antigeno pcv. MX2009006066A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87031106P 2006-12-15 2006-12-15
PCT/US2007/087628 WO2008076915A2 (en) 2006-12-15 2007-12-14 Treatment of pigs with pcv2 antigen

Publications (1)

Publication Number Publication Date
MX2009006066A true MX2009006066A (es) 2009-06-17

Family

ID=39537011

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009006066A MX2009006066A (es) 2006-12-15 2007-12-14 Tratamiento de cerdos con el antigeno pcv.

Country Status (21)

Country Link
US (4) US8865183B2 (es)
EP (3) EP2094872B2 (es)
JP (1) JP5200223B2 (es)
KR (1) KR101619730B1 (es)
CN (2) CN107412761A (es)
AR (1) AR064363A1 (es)
AU (1) AU2007333857B2 (es)
BR (1) BRPI0721083A2 (es)
CA (1) CA2670836C (es)
CL (1) CL2007003648A1 (es)
DK (2) DK2094872T4 (es)
ES (2) ES2625460T5 (es)
HU (2) HUE033130T2 (es)
MX (1) MX2009006066A (es)
PL (2) PL2094872T5 (es)
PT (2) PT2481420T (es)
RU (1) RU2520087C2 (es)
TW (1) TWI466682B (es)
UA (1) UA103298C2 (es)
WO (1) WO2008076915A2 (es)
ZA (1) ZA200903299B (es)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2733428T3 (es) 2004-12-30 2019-11-29 Boehringer Ingelheim Animal Health Usa Inc Composiciones inmunogénicas frente a PCV2 y métodos para producir composiciones de este tipo
US7833707B2 (en) 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
US8834891B2 (en) 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
CN104383526B (zh) 2005-12-29 2018-09-18 贝林格尔.英格海姆维特梅迪卡有限公司 Pcv2免疫原性组合物用于减轻猪临床症状的用途
PL1968630T3 (pl) 2005-12-29 2018-08-31 Boehringer Ingelheim Vetmedica, Inc. Multiwalentne immunogenne kompozycje PCV2
US20100136060A1 (en) * 2006-11-22 2010-06-03 Boehringer Ingelheim Vetmedica, Inc. Methods of reducing porcine circovirus-associated disease outbreaks
US20100129397A1 (en) 2006-12-11 2010-05-27 Boehringer Ingelheim Vetmedica, Inc. Effective method of treatment of porcine circovirus and lawsonia intracellularis infections
EP2094872B2 (en) 2006-12-15 2020-02-19 Boehringer Ingelheim Animal Health USA Inc. Treatment of anti-PCV2 antibody seropositive pigs with PCV2 antigen
EP1941903A1 (en) 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxis and treatment of PRDC
EP1958644A1 (en) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Prevention and treatment of sub-clinical pcvd
GB0712160D0 (en) * 2007-06-22 2007-08-01 Univ Ghent Methods and compositions in the treatment of procine circoviral infection
US7829274B2 (en) 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
EP2242511A4 (en) 2008-01-23 2012-10-24 Boehringer Ingelheim Vetmed IMMUNOGENIC COMPOSITIONS OF MYCOPLASMA HYOPNEUMONIAE PCV2, AND METHODS FOR PRODUCING SUCH COMPOSITIONS
AR078253A1 (es) 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
MX352641B (es) * 2010-07-08 2017-12-01 United Biomedical Inc Vacuna contra pcv2 basada en peptidos de diseño.
UA114503C2 (uk) * 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv та mycoplasma hyopneumoniae
WO2014179200A1 (en) * 2013-04-30 2014-11-06 Boehringer Ingelheim Vetmedica, Inc. Orf2 protein of pcv2 subtype a (pcv2a) for use in cross-protection
US9649370B2 (en) 2013-05-08 2017-05-16 Protatek International, Inc. Vaccine for PCV2 and mycoplasma
WO2014187822A1 (en) * 2013-05-22 2014-11-27 Boehringer Ingelheim Espana, S.A. Method for the reduction of pcv-2 in a herd of swine
CN105451765A (zh) 2013-08-23 2016-03-30 勃林格殷格翰动物保健公司 猪圆环病毒2型(pcv2)亚单位疫苗
JP6821429B2 (ja) * 2013-09-25 2021-01-27 ゾエティス・サービシーズ・エルエルシー Pcv2b分岐ワクチン組成物及び使用方法
EA035265B1 (ru) 2013-10-02 2020-05-21 Бёрингер Ингельхайм Энимал Хелс Ю-Эс-Эй Инк. Вариант белка opc2 pcv2 и содержащие его вирусоподобные частицы
CN110354258A (zh) * 2013-12-03 2019-10-22 英特维特国际股份有限公司 抗猪圆环病毒2型的疫苗
US10130699B2 (en) 2013-12-03 2018-11-20 Intervet Inc. Vaccine against Lawsonia intracellularis and porcine circovirus 2
JP2018504424A (ja) 2015-02-04 2018-02-15 インターベット インターナショナル ベー. フェー. 豚における無症候性ローソニア感染症に対する使用のためのワクチン
CN107531760A (zh) 2015-03-30 2018-01-02 勃林格殷格翰动物保健公司 Pcv2 orf2载体平台
WO2017113050A1 (zh) * 2015-12-28 2017-07-06 财团法人农业科技研究院 猪圆环病毒2型的外鞘蛋白质的制备方法及含该外鞘蛋白质的医药组合物
EP3432920A1 (en) 2016-03-23 2019-01-30 Intervet International B.V. A vaccine for intradermal application against pcv2 and prrs virus infection
RU2018137034A (ru) 2016-03-23 2020-04-23 Интервет Интернэшнл Б.В. Комбинированная вакцина против вируса pcv2 и инфекции mycoplasma hyopneumoniae
JP2019509302A (ja) 2016-03-23 2019-04-04 インターベット インターナショナル ベー. フェー. アルブミンを含むpcv2及びprrsウイルス感染症に対する混合ワクチン
EP3609533A1 (en) 2017-04-13 2020-02-19 Intervet International B.V. Vaccines containing swine pathogens for associated non-mixed use
EP3661548B1 (en) 2017-08-03 2024-06-26 Intervet International B.V. A vaccine comprising a pcv2 orf2 protein of genotype 2b
CN108795863A (zh) * 2018-06-06 2018-11-13 广西大学 体外感染猪圆环病毒2型建立猪肺泡巨噬细胞炎症模型的方法
WO2019238611A1 (en) * 2018-06-11 2019-12-19 Ceva Sante Animale Vaccination against porcine circoviruses
KR102288367B1 (ko) * 2018-11-15 2021-08-11 주식회사 바이오앱 식물체에서 바이러스-유사 입자를 발현하는 재조합 벡터 및 이를 이용한 써코바이러스-유사 입자를 포함하는 백신 조성물의 제조방법
CA3136141A1 (en) 2019-04-04 2020-10-08 Boehringer Ingelheim Animal Health USA Inc. Porcine circovirus type 3 (pcv3) vaccines, and production and uses thereof
MX2022003090A (es) 2019-09-12 2022-04-11 Intervet Int Bv Vacuna combinada para ser administrable intradermicamente.
CA3176154A1 (en) 2020-04-20 2021-10-28 Maarten Hendrik Witvliet A combination of vaccines to prophylactically treat a pig
BR112023001324A2 (pt) 2020-07-24 2023-02-14 Boehringer Ingelheim Animal Health Usa Inc Combinação de vacina de suíno
MX2023005049A (es) 2020-10-29 2023-05-17 Intervet Int Bv Vacuna combinada para proteger a los cerdos contra diversos trastornos.
CN112725291B (zh) * 2020-12-30 2023-07-04 西北农林科技大学 一种gas样基序突变的pcv2毒株及其制备方法和应用

Family Cites Families (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2909462A (en) 1955-12-08 1959-10-20 Bristol Myers Co Acrylic acid polymer laxative compositions
CA1247080A (en) 1983-03-08 1988-12-20 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
US5069901A (en) 1988-02-03 1991-12-03 Jones Elaine V Preparation of a recombinant subunit vaccine against pseudorabies infection
DK0454735T3 (da) 1989-01-23 1996-10-07 Auspharm Int Ltd Vaccine sammensætning
US5155037A (en) 1989-08-04 1992-10-13 The Texas A&M University System Insect signal sequences useful to improve the efficiency of processing and secretion of foreign genes in insect systems
US5202430A (en) * 1990-01-16 1993-04-13 University Of Tennessee Transmissible gastroenteritis virus genes
JP3187419B2 (ja) 1990-05-29 2001-07-11 アメリカン・サイアナミド・カンパニー ブタ肺炎ワクチンおよびその製造方法
US5565205A (en) 1990-08-16 1996-10-15 Solvay Animal Health, Inc. Inactivated Mycoplasma hypopneumoniae bacterin and method of use thereof
GB9023111D0 (en) * 1990-10-24 1990-12-05 Wellcome Found Expression system
ES2150419T3 (es) * 1990-11-01 2000-12-01 Univ Iowa State Res Found Inc Procedimiento de atenuacion bacteriana y vacuna.
US6042830A (en) 1992-08-05 2000-03-28 Boehringer Ingelheim Vetmedica, Inc. Viral agent associated with mystery swine disease
CA2076744C (en) 1991-08-26 2000-06-27 Danny W. Chladek Viral agent associated with mystery swine disease
US5580557A (en) * 1991-10-09 1996-12-03 Iowa State University Research Foundation, Inc. Live, avirulent salmonella choleraesuis vaccine used for inducing an immune response in animals
US5338543A (en) 1992-02-27 1994-08-16 Ambico, Inc. Thimerosal inactivated mycoplasma hyopneumoniae vaccine
CA2189979C (en) * 1994-05-10 2011-04-19 Hsien-Jue Chu Improved modified live brsv vaccine
US5885823A (en) * 1995-06-05 1999-03-23 Nobl Laboratories, Inc. Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents
WO1998006835A2 (en) 1996-08-16 1998-02-19 The Texas A & M University System Modifying insect cell gylcosylation pathways with baculovirus expression vectors
DK0835930T3 (da) * 1996-10-09 2001-06-18 Akzo Nobel Nv Europæiske vaccinestammer af porcint reproduktions- og respirationssyndrom-virus. (PRRSV)
US6517843B1 (en) * 1999-08-31 2003-02-11 Merial Reduction of porcine circovirus-2 viral load with inactivated PCV-2
US7211379B2 (en) * 1997-10-03 2007-05-01 Merial Sas Prevention of myocarditis, abortion and intrauterine infection associated with porcine circovirus-2
FR2781159B1 (fr) * 1998-07-06 2000-10-06 Merial Sas Vaccin circovirus et parvovirus porcin
UA78180C2 (uk) 1997-10-03 2007-03-15 Меріаль Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти
US20060029617A1 (en) * 1997-10-03 2006-02-09 Charreyre Catherine E Porcine circovirus and Helicobacter combination vaccines and methods of use
US7192594B2 (en) * 1997-10-03 2007-03-20 Merial Limited Postweaning multisystemic wasting syndrome and porcine circovirus from pigs
US6391314B1 (en) * 1997-10-03 2002-05-21 Merial Porcine circoviruses vaccines diagnostic reagents
FR2772047B1 (fr) * 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
US20040062775A1 (en) * 1997-12-05 2004-04-01 Agence Francaise De Securite Sanitaire Des Aliments Circovirus sequences associated with piglet weight loss disease (PWD)
PT2363488E (pt) * 1997-12-11 2015-01-13 Univ Belfast Síndrome multi-sistémica do definhamento pós-desmame de porcos
WO1999045956A1 (en) * 1998-03-13 1999-09-16 University Of Georgia Research Foundation, Inc. Vaccines against circovirus infections
US6294176B1 (en) * 1998-07-10 2001-09-25 Schering-Plough Veterinary Corp. Recombinant raccoonpox virus and uses thereof as a vaccine in mammalian and avian species
EP1050584B1 (en) 1998-11-19 2006-10-18 Azwell Inc. Recombinant lysophosphatidic acid phosphatase
FR2789695B1 (fr) * 1999-02-11 2003-03-07 Merial Sas Vecteurs et vaccins viraux a base d'adenovirus porcins recombines et replicatifs
WO2000072063A1 (en) 1999-05-21 2000-11-30 Nanovation Technologies, Inc. M x N OPTICAL CROSS-CONNECT
US6497883B1 (en) * 1999-06-10 2002-12-24 Merial Porcine circovirus recombinant poxvirus vaccine
US6943152B1 (en) * 1999-06-10 2005-09-13 Merial DNA vaccine-PCV
WO2001017556A1 (fr) 1999-09-07 2001-03-15 Shionogi & Co., Ltd. Préparations vaccinales administrables par les muqueuses
US6656478B1 (en) 1999-11-12 2003-12-02 Samuel D. Charles Cross-protective salmonella vaccines
WO2001045735A2 (en) 1999-12-21 2001-06-28 Merial Compositions and vaccines containing antigen(s) of cryptosporidium parvum and of another enteric pathogen
WO2001096377A2 (en) * 2000-06-15 2001-12-20 Purdue Research Foundation Vaccine for congenital tremors in pigs
US6808900B2 (en) * 2000-06-15 2004-10-26 Manitoba, University Of Cryptosporidium parvum antigens, antibodies thereto and diagnostic and therapeutic compositions thereof
PT1303265E (pt) 2000-07-20 2007-10-09 Lauras As ''utilização de inibidores da cox-2 como imuno-estimulantes, no tratamento do vih ou da sida''
US7018638B2 (en) * 2000-12-19 2006-03-28 Wyeth Mycoplasma hyopneumoniae bacterin vaccine
MY129765A (en) 2000-12-19 2007-04-30 Wyeth Corp Improved mycoplasma hyopneumoniae bacterin vaccine
JP2002247979A (ja) 2001-02-23 2002-09-03 Nippon Biologicals Inc マレック病ワクチンおよびその製造方法
MY148759A (en) * 2001-03-27 2013-05-31 Univ Saskatchewan Methods to culture circovirus
US20030096377A1 (en) * 2001-06-28 2003-05-22 Virginia Tech Intellectual Properties, Inc. Differential PCR-RFLP assay for detecting and distinguishing between nonpathogenic PCV-1 and pathogenic PCV-2
CZ305781B6 (cs) * 2001-07-02 2016-03-16 Zoetis Services Llc Výroba vakcíny Mycoplasma hyopneumoniae
US7361352B2 (en) * 2001-08-15 2008-04-22 Acambis, Inc. Influenza immunogen and vaccine
US7276353B2 (en) 2001-12-12 2007-10-02 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
US7279166B2 (en) * 2001-12-12 2007-10-09 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
US6841364B2 (en) * 2002-01-22 2005-01-11 Protatek International, Inc. Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof
WO2003068933A2 (en) 2002-02-14 2003-08-21 Novavax, Inc. Optimization of gene sequences of virus-like particles for expression in insect cells
US20030199581A1 (en) 2002-03-13 2003-10-23 Seligson Allen L. Boswellin compositions enhanced with 3-beta-acetyl-11-keto-beta-boswellic acid ("AKBA") industrial manufacture and uses
US20030215455A1 (en) * 2002-05-14 2003-11-20 Bailey Reynolds Vaccine stabilizer and method of use
AU2002951692A0 (en) 2002-09-23 2002-10-17 Vital Biotech (Hong Kong) Limited Improvements in or relating to vaccines
US7408636B2 (en) 2002-10-31 2008-08-05 Chemimage Corporation Method and apparatus for dark field chemical imaging
EP1599164B1 (en) 2003-02-03 2015-04-08 Cerebus Biologicals, Inc. Methods for treating, preventing and detecting helicobacter infection
US7563449B2 (en) 2003-04-21 2009-07-21 Pfizer Inc, Methods for reducing cattle reproductive diseases
CN1458167A (zh) * 2003-06-02 2003-11-26 中国农业科学院哈尔滨兽医研究所 截短表达的猪圆环病毒ⅱ型衣壳蛋白抗原及其应用
US7335361B2 (en) * 2003-06-09 2008-02-26 Animal Technology Institute Taiwan Fusion antigen used as vaccine
KR101146545B1 (ko) * 2003-07-24 2012-07-05 메리얼 리미티드 수중유 에멀젼을 포함하는 백신 제형물
SG144909A1 (en) * 2003-07-25 2008-08-28 Boehringer Ingelheim Vetmed Lawsonia intracellularis of european origin and vaccines, diagnostic agents and methods of use thereof
FR2861731B1 (fr) * 2003-10-30 2006-02-24 Centre Nat Rech Scient Nouvelle proteine de fixation du phosphate, compositions pharmaceutiques la contenant et ses utilisations
CN1942204A (zh) 2004-04-26 2007-04-04 株式会社中央疫苗研究所 用于猪呼吸病的灭活混合疫苗及其制备方法
CN1579553A (zh) * 2004-05-18 2005-02-16 浙江大学 Ii型猪圆环病毒核酸疫苗的制备方法及其应用
KR100478845B1 (ko) 2004-06-22 2005-03-24 채찬희 돼지 이유자돈 전신성 소모성 증후군 예방 및 치료용 생물학적 조성물
AU2005319716A1 (en) 2004-06-30 2006-06-29 Id Biomedical Corporation Of Quebec Vaccine compositions for treating coronavirus infection
US7833707B2 (en) * 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
US7700285B1 (en) * 2005-12-29 2010-04-20 Boehringer Ingelheim Vetmedica, Inc. PCV2 immunogenic compositions and methods of producing such compositions
RU2007130801A (ru) * 2005-01-13 2009-02-20 Берингер Ингельхайм Ветмедика Гмбх (De) Улучшенные вакцины против репродуктивно-респираторного синдрома свиней (prrs)
US7300785B2 (en) * 2005-02-03 2007-11-27 Universiteit Ghent Culturing circular ssDNA viruses for the production of vaccines
US8834891B2 (en) * 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
EP1869471B1 (en) * 2005-04-13 2016-06-08 Merial, Inc. Method for porcine circovirus production
US7691368B2 (en) 2005-04-15 2010-04-06 Merial Limited Vaccine formulations
TW200643171A (en) * 2005-06-07 2006-12-16 Temasek Life Sciences Lab Ltd Porcine circovirus type 2 vaccines
CN1769434A (zh) * 2005-08-30 2006-05-10 广东省农业科学院兽医研究所 一种猪圆环病毒2型重组腺病毒及其构建方法和应用
US20080248061A1 (en) * 2005-09-09 2008-10-09 Intervet International B.V. Pcv-2 Vaccine
CN104383526B (zh) * 2005-12-29 2018-09-18 贝林格尔.英格海姆维特梅迪卡有限公司 Pcv2免疫原性组合物用于减轻猪临床症状的用途
PL1968630T3 (pl) * 2005-12-29 2018-08-31 Boehringer Ingelheim Vetmedica, Inc. Multiwalentne immunogenne kompozycje PCV2
US20100136060A1 (en) * 2006-11-22 2010-06-03 Boehringer Ingelheim Vetmedica, Inc. Methods of reducing porcine circovirus-associated disease outbreaks
US20100129397A1 (en) 2006-12-11 2010-05-27 Boehringer Ingelheim Vetmedica, Inc. Effective method of treatment of porcine circovirus and lawsonia intracellularis infections
EP2094872B2 (en) * 2006-12-15 2020-02-19 Boehringer Ingelheim Animal Health USA Inc. Treatment of anti-PCV2 antibody seropositive pigs with PCV2 antigen
EP1941903A1 (en) 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxis and treatment of PRDC
EP1958644A1 (en) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Prevention and treatment of sub-clinical pcvd
GB0712160D0 (en) * 2007-06-22 2007-08-01 Univ Ghent Methods and compositions in the treatment of procine circoviral infection
US8846867B2 (en) * 2007-06-26 2014-09-30 The Trustees Of The University Of Pennsylvania Isolation of anti-desmoglein 1 antibodies by phage display of pemphigus foliaceus autoantibodies
US20090017064A1 (en) 2007-07-10 2009-01-15 Wyeth Methods and Compositions for Immunizing Pigs Against Porcine Circovirus
US7829274B2 (en) * 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
WO2009103037A1 (en) 2008-02-15 2009-08-20 Boehringer Ingelheim Vetmedica, Inc. Methods and compositions for reducing the impact of enteric diseases
US8444989B1 (en) 2008-04-18 2013-05-21 Boehringer Ingelheim Vetmedica Gmbh One dose vaccination against mycoplasma infections of pigs
AR078253A1 (es) 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
DK2547770T3 (da) 2010-03-16 2020-03-02 Virginia Tech Intellectual Properties Inc Levende svækket kimær porcint circovirusvaccine
WO2012033911A2 (en) 2010-09-08 2012-03-15 The Johns Hopkins University Polyionic papilloma virus-like particle (vlp) vaccines
CN103122352B (zh) 2012-09-27 2015-02-11 华中农业大学 一种猪圆环病毒2型重组杆状病毒及制备方法和应用
CN107531760A (zh) 2015-03-30 2018-01-02 勃林格殷格翰动物保健公司 Pcv2 orf2载体平台

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