MX2009005048A - Nuevo proceso para la preparacion de derivados de 2-imino-tiazolidin-4-ona. - Google Patents
Nuevo proceso para la preparacion de derivados de 2-imino-tiazolidin-4-ona.Info
- Publication number
- MX2009005048A MX2009005048A MX2009005048A MX2009005048A MX2009005048A MX 2009005048 A MX2009005048 A MX 2009005048A MX 2009005048 A MX2009005048 A MX 2009005048A MX 2009005048 A MX2009005048 A MX 2009005048A MX 2009005048 A MX2009005048 A MX 2009005048A
- Authority
- MX
- Mexico
- Prior art keywords
- thiazolidin
- derivatives
- preparation
- imino
- new process
- Prior art date
Links
- HYMJHROUVPWYNQ-UHFFFAOYSA-N 2-amino-1,3-thiazol-4-one Chemical class NC1=NC(=O)CS1 HYMJHROUVPWYNQ-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- NOLHRFLIXVQPSZ-UHFFFAOYSA-N 1,3-thiazolidin-4-one Chemical class O=C1CSCN1 NOLHRFLIXVQPSZ-UHFFFAOYSA-N 0.000 abstract 1
- 229940125721 immunosuppressive agent Drugs 0.000 abstract 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/54—Nitrogen and either oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2006054409 | 2006-11-23 | ||
| PCT/IB2007/054752 WO2008062376A2 (en) | 2006-11-23 | 2007-11-22 | New process for the preparation of 2-imino-thiazolidin-4-one derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009005048A true MX2009005048A (es) | 2009-05-25 |
Family
ID=39316391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009005048A MX2009005048A (es) | 2006-11-23 | 2007-11-22 | Nuevo proceso para la preparacion de derivados de 2-imino-tiazolidin-4-ona. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8263780B2 (OSRAM) |
| EP (2) | EP2094676B1 (OSRAM) |
| JP (1) | JP4669564B2 (OSRAM) |
| KR (1) | KR101255879B1 (OSRAM) |
| CN (2) | CN103087004A (OSRAM) |
| AU (1) | AU2007323042B2 (OSRAM) |
| CA (1) | CA2669069C (OSRAM) |
| DK (2) | DK2489662T3 (OSRAM) |
| ES (2) | ES2410793T3 (OSRAM) |
| IL (1) | IL198847A (OSRAM) |
| MX (1) | MX2009005048A (OSRAM) |
| TW (1) | TWI460166B (OSRAM) |
| WO (1) | WO2008062376A2 (OSRAM) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE43833E1 (en) | 2003-11-21 | 2012-11-27 | Actelion Pharmaceuticals Ltd. | Thiazolidin-4-one derivatives |
| SI1689726T1 (sl) | 2003-11-21 | 2011-01-31 | Actelion Pharmaceuticals Ltd | Derivati 5-(benz-(z)-iliden)-tiazolidin-4-ona kot imunosupresivna sredstva |
| US8912340B2 (en) | 2006-11-23 | 2014-12-16 | Actelion Pharmaceuticals Ltd. | Process for the preparation of 2-imino-thiazolidin-4-one derivatives |
| PT2278960T (pt) | 2008-03-17 | 2017-03-09 | Actelion Pharmaceuticals Ltd | Regime de dosagem para um agonista seletivo do recetor s1p1 |
| GB0819182D0 (en) | 2008-10-20 | 2008-11-26 | Actelion Pharmaceuticals Ltd | Crystalline forms |
| RS60408B1 (sr) * | 2012-08-17 | 2020-07-31 | Actelion Pharmaceuticals Ltd | Postupak za pripremanje (2z,5z)-5-(3-hloro-4-((r)-2,3-dihidroksipropoksi)benziliden)-2-(propilimino)-3-(o-tolil)tiazolidin-4-ona i međujedinjenja upotrebljena u pomenutom postupku |
| EP3256125B1 (en) | 2014-12-11 | 2022-01-26 | Actelion Pharmaceuticals Ltd | Dosing regimen for ponesimod, a selective s1p1 receptor agonist |
| MA41139A (fr) | 2014-12-11 | 2017-10-17 | Actelion Pharmaceuticals Ltd | Combinaison pharmaceutique comportant un agoniste sélectif du récepteur sip1 |
| JOP20190207A1 (ar) | 2017-03-14 | 2019-09-10 | Actelion Pharmaceuticals Ltd | تركيبة صيدلانية تشتمل على بونيسيمود |
| US11220488B2 (en) | 2017-09-19 | 2022-01-11 | Teva Pharmaceuticals International Gmbh | Crystalline polymorph of Ponesimod |
| US11186556B1 (en) | 2018-10-16 | 2021-11-30 | Celgene Corporation | Salts of a thiazolidinone compound, solid forms, compositions and methods of use thereof |
| US11014897B1 (en) | 2018-10-16 | 2021-05-25 | Celgene Corporation | Solid forms comprising a thiazolidinone compound, compositions and methods of use thereof |
| US11014940B1 (en) | 2018-10-16 | 2021-05-25 | Celgene Corporation | Thiazolidinone and oxazolidinone compounds and formulations |
| US11013723B1 (en) | 2018-10-16 | 2021-05-25 | Celgene Corporation | Solid forms of a thiazolidinone compound, compositions and methods of use thereof |
| BR112022000185A2 (pt) * | 2019-07-10 | 2022-02-22 | Bayer Ag | Método de preparação de 2-(fenilimino)-1,3-tiazolidin-4-onas |
| JP2022540115A (ja) * | 2019-07-10 | 2022-09-14 | バイエル・アクチエンゲゼルシヤフト | ２－（フェニルイミノ）－１，３－チアゾリジン－４－オン類の調製方法 |
| KR20220093330A (ko) | 2019-10-31 | 2022-07-05 | 이도르시아 파마슈티컬스 리미티드 | Cxcr7 안타고니스트와 s1p1 수용체 조절인자의 조합 |
| KR20200019639A (ko) | 2020-01-30 | 2020-02-24 | 전대연 | 만남의 스마트 도착시스템 |
| KR20220143032A (ko) * | 2020-02-18 | 2022-10-24 | 바이엘 악티엔게젤샤프트 | 2-(페닐이미노)-3-알킬-1,3-티아졸리딘-4-온의 제조 방법 |
| WO2023022896A1 (en) | 2021-08-17 | 2023-02-23 | Teva Czech Industries S.R.O | Polymorphs of ponesimod |
| EP4212156A1 (en) | 2022-01-13 | 2023-07-19 | Abivax | Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator |
| WO2023152691A1 (en) * | 2022-02-10 | 2023-08-17 | Metrochem Api Pvt Ltd | Process for the preparation of ponesimod and its intermediates thereof |
| CN117924210A (zh) * | 2024-01-22 | 2024-04-26 | 赣南师范大学 | 一种2-亚氨基噻唑烷-4-酮类化合物的制备方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3077402A (en) * | 1954-12-06 | 1963-02-12 | Polaroid Corp | Photographic color processes, products, and compositions |
| NL270002A (OSRAM) | 1960-10-08 | |||
| OA03835A (fr) * | 1970-07-17 | 1971-12-24 | Rhone Poulenc Sa | Nouveaux dérivés de la thiazolidine, leur préparation et les compositions qui les contiennent. |
| EP0526598B1 (en) | 1990-04-27 | 1996-12-18 | Orion-Yhtymà Oy | New pharmacologically active catechol derivatives |
| TW221689B (OSRAM) * | 1991-08-27 | 1994-03-11 | Otsuka Pharma Co Ltd | |
| DK0638075T3 (da) * | 1993-02-26 | 2002-02-18 | Otsuka Pharma Co Ltd | Thiazol- eller imidazolderivater som Maillard-reaktionsinhibitorer |
| KR960022486A (ko) | 1994-12-29 | 1996-07-18 | 김준웅 | 신규 티아졸리딘-4-온 유도체 |
| US6353006B1 (en) * | 1999-01-14 | 2002-03-05 | Bayer Corporation | Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents |
| WO2001019807A1 (en) | 1999-09-14 | 2001-03-22 | Shionogi & Co., Ltd. | 2-imino-1,3-thiazine derivatives |
| IL144229A (en) * | 1999-11-12 | 2006-10-05 | Fujimoto Brothers Co Ltd | New history of N) –2– cyanoimino) thiazolidine – 4 – on |
| US20050019825A9 (en) * | 2002-03-15 | 2005-01-27 | Qing Dong | Common ligand mimics: pseudothiohydantoins |
| AU2003255528B2 (en) | 2002-07-10 | 2009-07-16 | Merck Serono Sa | Azolidinone-vinyl fused-benzene derivatives |
| GB0217152D0 (en) | 2002-07-24 | 2002-09-04 | Novartis Ag | Organic compounds |
| ES2315566T3 (es) * | 2002-11-22 | 2009-04-01 | Smithkline Beecham Corporation | Tiazolidin-4-onas para inhibir proteinas hyak3. |
| US20040167192A1 (en) * | 2003-01-16 | 2004-08-26 | David Solow-Cordero | Methods of treating conditions associated with an Edg-7 receptor |
| SI1689726T1 (sl) * | 2003-11-21 | 2011-01-31 | Actelion Pharmaceuticals Ltd | Derivati 5-(benz-(z)-iliden)-tiazolidin-4-ona kot imunosupresivna sredstva |
| WO2005082901A1 (en) * | 2004-02-25 | 2005-09-09 | Smithkline Beecham Corporation | Novel chemical compounds |
| WO2006094233A1 (en) * | 2005-03-03 | 2006-09-08 | Sirtris Pharmaceuticals, Inc. | N,n'-dicyclic isothiourea sirtuin modulators |
| PT2278960T (pt) * | 2008-03-17 | 2017-03-09 | Actelion Pharmaceuticals Ltd | Regime de dosagem para um agonista seletivo do recetor s1p1 |
| GB0819182D0 (en) * | 2008-10-20 | 2008-11-26 | Actelion Pharmaceuticals Ltd | Crystalline forms |
-
2007
- 2007-11-22 CN CN2012105461683A patent/CN103087004A/zh active Pending
- 2007-11-22 WO PCT/IB2007/054752 patent/WO2008062376A2/en not_active Ceased
- 2007-11-22 DK DK12000613.5T patent/DK2489662T3/da active
- 2007-11-22 EP EP07849225.3A patent/EP2094676B1/en active Active
- 2007-11-22 CA CA2669069A patent/CA2669069C/en active Active
- 2007-11-22 AU AU2007323042A patent/AU2007323042B2/en active Active
- 2007-11-22 MX MX2009005048A patent/MX2009005048A/es active IP Right Grant
- 2007-11-22 US US12/516,055 patent/US8263780B2/en active Active
- 2007-11-22 CN CN2007800431941A patent/CN101541772B/zh active Active
- 2007-11-22 TW TW096144311A patent/TWI460166B/zh active
- 2007-11-22 KR KR1020097011745A patent/KR101255879B1/ko active Active
- 2007-11-22 ES ES07849225T patent/ES2410793T3/es active Active
- 2007-11-22 EP EP12000613.5A patent/EP2489662B1/en active Active
- 2007-11-22 JP JP2009537744A patent/JP4669564B2/ja active Active
- 2007-11-22 ES ES12000613.5T patent/ES2523401T3/es active Active
- 2007-11-22 DK DK07849225.3T patent/DK2094676T3/da active
-
2009
- 2009-05-20 IL IL198847A patent/IL198847A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| DK2489662T3 (da) | 2014-10-20 |
| JP2010510976A (ja) | 2010-04-08 |
| EP2489662B1 (en) | 2014-08-06 |
| AU2007323042B2 (en) | 2012-12-20 |
| JP4669564B2 (ja) | 2011-04-13 |
| CN101541772A (zh) | 2009-09-23 |
| CN103087004A (zh) | 2013-05-08 |
| CA2669069C (en) | 2015-02-17 |
| US8263780B2 (en) | 2012-09-11 |
| WO2008062376A3 (en) | 2008-07-10 |
| TWI460166B (zh) | 2014-11-11 |
| BRPI0718986A2 (pt) | 2014-02-11 |
| US20110201821A2 (en) | 2011-08-18 |
| EP2094676A2 (en) | 2009-09-02 |
| US20100317867A1 (en) | 2010-12-16 |
| IL198847A (en) | 2015-07-30 |
| ES2523401T3 (es) | 2014-11-25 |
| KR101255879B1 (ko) | 2013-04-17 |
| WO2008062376A2 (en) | 2008-05-29 |
| AU2007323042A1 (en) | 2008-05-29 |
| ES2410793T3 (es) | 2013-07-03 |
| IL198847A0 (en) | 2010-02-17 |
| CA2669069A1 (en) | 2008-05-29 |
| EP2094676B1 (en) | 2013-04-10 |
| EP2489662A1 (en) | 2012-08-22 |
| DK2094676T3 (da) | 2013-06-10 |
| CN101541772B (zh) | 2013-04-17 |
| KR20090081009A (ko) | 2009-07-27 |
| TW200831474A (en) | 2008-08-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |