MX2009004526A - Nuevos derivados de benzamida como antagonistas de la bradiqunina. - Google Patents

Nuevos derivados de benzamida como antagonistas de la bradiqunina.

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Publication number
MX2009004526A
MX2009004526A MX2009004526A MX2009004526A MX2009004526A MX 2009004526 A MX2009004526 A MX 2009004526A MX 2009004526 A MX2009004526 A MX 2009004526A MX 2009004526 A MX2009004526 A MX 2009004526A MX 2009004526 A MX2009004526 A MX 2009004526A
Authority
MX
Mexico
Prior art keywords
benzamide derivatives
new benzamide
brad ykinin
ykinin antagonists
new
Prior art date
Application number
MX2009004526A
Other languages
English (en)
Inventor
Istvan Vago
Eva Bozo
Sandor Farkas
Gyoergy Keserue
Monika Vastag
Gyula Beke
Katalin Hornok
Eva Schmidt
Eva Szentirmay
Original Assignee
Richter Gedeon Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt
Publication of MX2009004526A publication Critical patent/MX2009004526A/es

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    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
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Abstract

La presente invención se refiere a nuevos derivados de fenilsulfamoibenzamida de la fórmula (I) (ver fórmula (I)) en donde R1-R5 son como se define en las reivindicaciones y a los antípodas ópticos o racematos y/o a las sales y/o hidratos y/o solvatos de los mismos, los cuales son antagonistas selectivos de la bradiquinina B1, a los procesos para producir estos mismos compuestos, alas composiciones farmacológicas que los contienen y a su uso en la terapia o prevención de estados dolorosos e inflamatorios.
MX2009004526A 2006-10-27 2007-10-27 Nuevos derivados de benzamida como antagonistas de la bradiqunina. MX2009004526A (es)

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HU0600808A HUP0600808A3 (en) 2006-10-27 2006-10-27 New benzamide derivatives as bradykinin antagonists, process for their preparation and pharmaceutical compositions containing them
PCT/HU2007/000102 WO2008068540A1 (en) 2006-10-27 2007-10-27 New benzamide derivatives as bradykinin antagonists

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HUP0600810A3 (en) * 2006-10-27 2008-09-29 Richter Gedeon Nyrt New sulfonamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them
WO2009053763A1 (en) * 2007-10-27 2009-04-30 Richter Gedeon Nyrt. New non-peptide derivatives as bradykinin bl antagonists
EA201170351A1 (ru) * 2008-08-21 2011-08-30 Рихтер Гедеон Нирт. Способы лечения невропатической боли
JP2012500801A (ja) * 2008-08-21 2012-01-12 リヒター ゲデオン ニルバーノシャン ミーケデーレスベニュタールシャシャーグ Ｃｎｓ疾患の治療法
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KR101676850B1 (ko) 2015-04-23 2016-11-18 한일화섬 주식회사 내구성이 우수한 스피커용 댐퍼 및 그 제조 방법
TW202202495A (zh) 2020-03-26 2022-01-16 匈牙利商羅特格登公司 作為ｇａｍｍａ－胺基丁酸Ａ受體次單元ａｌｐｈａ ５受體調節劑之㖠啶及吡啶并〔３，４－ｃ〕嗒𠯤衍生物
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HUP0600810A3 (en) 2006-10-27 2008-09-29 Richter Gedeon Nyrt New sulfonamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them
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