HRP20130836T1 - New benzamide derivatives as bradykinin antagonists - Google Patents
New benzamide derivatives as bradykinin antagonistsInfo
- Publication number
- HRP20130836T1 HRP20130836T1 HRP20130836TT HRP20130836T HRP20130836T1 HR P20130836 T1 HRP20130836 T1 HR P20130836T1 HR P20130836T T HRP20130836T T HR P20130836TT HR P20130836 T HRP20130836 T HR P20130836T HR P20130836 T1 HRP20130836 T1 HR P20130836T1
- Authority
- HR
- Croatia
- Prior art keywords
- benzamide derivatives
- bradykinin antagonists
- new benzamide
- new
- bradykinin
- Prior art date
Links
- 150000003936 benzamides Chemical class 0.000 title 1
- 239000003152 bradykinin antagonist Substances 0.000 title 1
Classifications
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- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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HU0600808A HUP0600808A3 (en) | 2006-10-27 | 2006-10-27 | New benzamide derivatives as bradykinin antagonists, process for their preparation and pharmaceutical compositions containing them |
PCT/HU2007/000102 WO2008068540A1 (en) | 2006-10-27 | 2007-10-27 | New benzamide derivatives as bradykinin antagonists |
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HRP20130836T1 true HRP20130836T1 (en) | 2013-10-11 |
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HRP20130836TT HRP20130836T1 (en) | 2006-10-27 | 2013-09-10 | New benzamide derivatives as bradykinin antagonists |
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EP (1) | EP2076491B1 (hr) |
JP (1) | JP5274470B2 (hr) |
KR (1) | KR101321257B1 (hr) |
CN (1) | CN101528685B (hr) |
AU (1) | AU2007330575B2 (hr) |
BR (1) | BRPI0718436B8 (hr) |
CA (1) | CA2667387C (hr) |
CU (1) | CU23857B1 (hr) |
CY (1) | CY1114354T1 (hr) |
DK (1) | DK2076491T3 (hr) |
EA (1) | EA014498B1 (hr) |
ES (1) | ES2431143T3 (hr) |
GE (1) | GEP20125382B (hr) |
HK (1) | HK1128472A1 (hr) |
HR (1) | HRP20130836T1 (hr) |
HU (1) | HUP0600808A3 (hr) |
IL (1) | IL197585A (hr) |
MA (1) | MA30916B1 (hr) |
MX (1) | MX2009004526A (hr) |
MY (1) | MY148476A (hr) |
NO (1) | NO342588B1 (hr) |
NZ (1) | NZ575764A (hr) |
PL (1) | PL2076491T3 (hr) |
PT (1) | PT2076491E (hr) |
SI (1) | SI2076491T1 (hr) |
TN (1) | TN2009000109A1 (hr) |
UA (1) | UA101602C2 (hr) |
WO (1) | WO2008068540A1 (hr) |
Families Citing this family (12)
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HUP0600810A3 (en) * | 2006-10-27 | 2008-09-29 | Richter Gedeon Nyrt | New sulfonamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them |
HUP0600809A3 (en) * | 2006-10-27 | 2008-09-29 | Richter Gedeon Nyrt | New phenylsulfamoyl-benzamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them |
US20100298299A1 (en) * | 2007-10-27 | 2010-11-25 | Istvan Vago | non-peptide derivatives as bradykinin b1 antagonists |
US20100048629A1 (en) * | 2008-08-21 | 2010-02-25 | Allyson Gage | Methods for treating neuropathic pain |
AU2009282822A1 (en) * | 2008-08-21 | 2010-02-25 | Richter Gedeon Nyrt. | Methods for treating CNS disorders |
AU2010217606C1 (en) * | 2009-02-26 | 2017-01-19 | Boehringer Ingelheim International Gmbh | Compounds as bradykinin B1 antagonists |
ES2350077B1 (es) | 2009-06-04 | 2011-11-04 | Laboratorios Salvat, S.A. | Compuestos inhibidores de 11beta-hidroxiesteroide deshidrogenasa de tipo 1. |
US8912221B2 (en) * | 2010-12-27 | 2014-12-16 | Hoffmann-La Roche Inc. | Biaryl amide derivatives |
CN107205972A (zh) * | 2014-04-23 | 2017-09-26 | X-Rx股份有限公司 | 自分泌运动因子的取代的n‑(2‑(氨基)‑2‑氧代乙基)苯甲酰胺抑制剂及它们的制备和在治疗lpa‑依赖的或lpa‑介导的疾病中的用途 |
KR101676850B1 (ko) | 2015-04-23 | 2016-11-18 | 한일화섬 주식회사 | 내구성이 우수한 스피커용 댐퍼 및 그 제조 방법 |
TW202202495A (zh) | 2020-03-26 | 2022-01-16 | 匈牙利商羅特格登公司 | 作為gamma-胺基丁酸A受體次單元alpha 5受體調節劑之㖠啶及吡啶并〔3,4-c〕嗒𠯤衍生物 |
HUP2100338A1 (hu) | 2021-09-29 | 2023-04-28 | Richter Gedeon Nyrt | GABAA ALFA5 receptor modulátor hatású biciklusos aminszármazékok |
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GB1279843A (en) | 1969-05-23 | 1972-06-28 | Science Union & Cie | Benzamidoethyl-piperazines and process for their preparation |
US5714497A (en) * | 1993-02-15 | 1998-02-03 | Sanofi | Compounds bearing sulphamoyl and amidino radicals, their preparation process and pharmaceutical compositions containing them |
US6451816B1 (en) * | 1997-06-20 | 2002-09-17 | Klinge Pharma Gmbh | Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression |
GB9804885D0 (en) * | 1998-03-06 | 1998-04-29 | Merck Sharp & Dohme | Therapeutic combination |
GB9913079D0 (en) | 1999-06-04 | 1999-08-04 | Novartis Ag | Organic compounds |
US6017961A (en) * | 1999-07-08 | 2000-01-25 | Flores; John Anthony | Ketamine and n-butyl-p-aminobezoate in PLO |
CA2413418A1 (en) * | 2000-06-21 | 2001-12-27 | Joseph B. Santella | Piperidine amides as modulators of chemokine receptor activity |
FR2822827B1 (fr) | 2001-03-28 | 2003-05-16 | Sanofi Synthelabo | Nouveaux derives de n-(arylsulfonyl) beta-aminoacides comportant un groupe aminomethyle substitue, leur procede de preparation et les compositions pharmaceutiques en contenant |
AU2002346048A1 (en) | 2001-06-07 | 2002-12-16 | Merck And Co., Inc. | Benzodiazepine bradykinin antagonists |
MXPA04000737A (es) * | 2001-07-24 | 2004-07-08 | Richter Gedeon Vegyeszet | Derivados de piperidina como antagonistas receptores de nmda. |
EP1501807A1 (en) | 2002-05-03 | 2005-02-02 | Elan Pharmaceuticals, Inc. | Sulfonylquinoxalone acetamide derivatives and related compounds as bradykinin antagonists |
US6908921B2 (en) | 2002-12-13 | 2005-06-21 | Merck & Co., Inc. | Quinoxalinone derivatives as bradykinin B1 antagonists |
US7393873B2 (en) * | 2003-07-02 | 2008-07-01 | Merck & Co., Inc. | Arylsulfonamide derivatives |
WO2005046601A2 (en) * | 2003-11-12 | 2005-05-26 | Merck & Co., Inc. | 4-phenyl piperdine sulfonyl glycine transporter inhibitors |
HU230518B1 (hu) * | 2005-12-20 | 2016-10-28 | Richter Gedeon Nyrt. | Bradykinin B1 receptor szelektív antagonista hatással rendelkező új fenatridin származékok, eljárás előállításukra, és az ezeket tartalmazó gyógyszerkészítmények |
HUP0600810A3 (en) * | 2006-10-27 | 2008-09-29 | Richter Gedeon Nyrt | New sulfonamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them |
HUP0600809A3 (en) * | 2006-10-27 | 2008-09-29 | Richter Gedeon Nyrt | New phenylsulfamoyl-benzamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them |
US20100298299A1 (en) * | 2007-10-27 | 2010-11-25 | Istvan Vago | non-peptide derivatives as bradykinin b1 antagonists |
CN102037355A (zh) | 2008-03-04 | 2011-04-27 | 里奇诊断学股份有限公司 | 基于多重生物标记物板块诊断和监测抑郁症 |
AU2009282822A1 (en) * | 2008-08-21 | 2010-02-25 | Richter Gedeon Nyrt. | Methods for treating CNS disorders |
US20100048629A1 (en) * | 2008-08-21 | 2010-02-25 | Allyson Gage | Methods for treating neuropathic pain |
WO2011094308A2 (en) | 2010-01-26 | 2011-08-04 | Ridge Diagnostics, Inc. | Multiple biomarker panels to stratify disease severity and monitor treatment of depression |
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