MX2009002987A - Expresion geneticamente programada de proteinas selectivamente sulfatadas en eubacterias. - Google Patents
Expresion geneticamente programada de proteinas selectivamente sulfatadas en eubacterias.Info
- Publication number
- MX2009002987A MX2009002987A MX2009002987A MX2009002987A MX2009002987A MX 2009002987 A MX2009002987 A MX 2009002987A MX 2009002987 A MX2009002987 A MX 2009002987A MX 2009002987 A MX2009002987 A MX 2009002987A MX 2009002987 A MX2009002987 A MX 2009002987A
- Authority
- MX
- Mexico
- Prior art keywords
- eubacteria
- novel
- genetically programmed
- programmed expression
- sulfated proteins
- Prior art date
Links
- 241000894006 Bacteria Species 0.000 title 1
- 108091005994 sulfated proteins Proteins 0.000 title 1
- 102000052866 Amino Acyl-tRNA Synthetases Human genes 0.000 abstract 3
- 108700028939 Amino Acyl-tRNA Synthetases Proteins 0.000 abstract 3
- 102000003960 Ligases Human genes 0.000 abstract 2
- 108090000364 Ligases Proteins 0.000 abstract 2
- CIQHWLTYGMYQQR-QMMMGPOBSA-N O(4')-sulfo-L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(OS(O)(=O)=O)C=C1 CIQHWLTYGMYQQR-QMMMGPOBSA-N 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 241001112695 Clostridiales Species 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84651906P | 2006-09-21 | 2006-09-21 | |
| US85521006P | 2006-10-28 | 2006-10-28 | |
| PCT/US2007/020459 WO2008036392A2 (en) | 2006-09-21 | 2007-09-20 | Genetically programmed expression of selectively sulfated proteins in eubacteria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009002987A true MX2009002987A (es) | 2009-04-28 |
Family
ID=39201110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009002987A MX2009002987A (es) | 2006-09-21 | 2007-09-20 | Expresion geneticamente programada de proteinas selectivamente sulfatadas en eubacterias. |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US8114652B2 (enExample) |
| EP (1) | EP2052083B1 (enExample) |
| JP (1) | JP5385143B2 (enExample) |
| KR (1) | KR20090074765A (enExample) |
| CN (1) | CN101516901B (enExample) |
| AU (1) | AU2007297610A1 (enExample) |
| BR (1) | BRPI0716963A2 (enExample) |
| CA (1) | CA2663052A1 (enExample) |
| ES (1) | ES2456331T3 (enExample) |
| IL (1) | IL197531A0 (enExample) |
| MX (1) | MX2009002987A (enExample) |
| PL (1) | PL2052083T3 (enExample) |
| PT (1) | PT2052083E (enExample) |
| RU (1) | RU2009110152A (enExample) |
| WO (1) | WO2008036392A2 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1490483B1 (en) * | 2001-04-19 | 2015-06-03 | The Scripps Research Institute | In vivo incorporation of unnatural amino acids |
| KR20050073559A (ko) * | 2002-10-16 | 2005-07-14 | 더 스크립스 리서치 인스티튜트 | 당단백질 합성 |
| CN103289960B (zh) | 2003-04-17 | 2017-04-26 | 斯克利普斯研究院 | 扩展真核生物遗传密码 |
| DE602004011789T2 (de) * | 2003-07-07 | 2009-02-12 | The Scripps Research Institute, La Jolla | Zusammensetzungen der orthogonalen Lysyl-tRNA und Aminoacyl-tRNA Synthetase Paaren und ihre Verwendungen |
| BRPI0819092A2 (pt) * | 2007-11-02 | 2014-10-14 | Scripps Research Inst | Evolução direcionada usando proteínas que compreendem aminoácidos não naturais. |
| US8658394B2 (en) * | 2011-02-02 | 2014-02-25 | Waterstone Pharmaceuticals | Methods, cells and systems for incorporating non-canonical amino acids into proteins |
| CN102888387B (zh) * | 2011-07-21 | 2015-03-18 | 中国科学院生物物理研究所 | 3-氯代酪氨酸翻译系统及其应用 |
| CN103571804B (zh) * | 2012-08-10 | 2015-08-12 | 中国科学院生物物理研究所 | 3-吡唑基酪氨酸翻译系统及其应用 |
| WO2015120287A2 (en) | 2014-02-06 | 2015-08-13 | Yale University | Compositions and methods of use thereof for making polypeptides with many instances of nonstandard amino acids |
| WO2016073079A2 (en) | 2014-09-26 | 2016-05-12 | Yale University | Compositions and methods for biocontainment of microorganisms |
| CN110117580B (zh) * | 2018-02-05 | 2021-12-14 | 中国科学院生物物理研究所 | 硒代酪氨酸翻译系统及其应用 |
| IL280198B1 (en) * | 2018-07-18 | 2025-09-01 | Regenxbio Inc | Treatment of mucopolysaccharidosis I with fully glycosylated human iduronidase-alpha-L (idus) |
| US12371817B2 (en) * | 2019-03-04 | 2025-07-29 | The Texas A&M University System | Methods of making and utilizing amber-obligated phage display libraries |
| US11149280B2 (en) | 2019-10-29 | 2021-10-19 | Yale University | Engineering organisms resistant to viruses and horizontally transferred genetic elements |
| CN111304234A (zh) * | 2020-02-27 | 2020-06-19 | 江南大学 | 一种适用于枯草芽孢杆菌的非天然氨基酸利用工具 |
| CN113789335B (zh) * | 2021-11-16 | 2022-03-15 | 江苏省中国科学院植物研究所 | 一种水蛭酪氨酸磺酸转移酶基因及其应用 |
| CN118389493B (zh) * | 2024-05-10 | 2025-04-11 | 北京大学 | 一种定点修饰的工程化tRNA及其应用 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6204016B1 (en) | 1998-01-29 | 2001-03-20 | The Board Of Regents Of The University Of Oklahoma | Tyrosylprotein sulfotransferases and methods of use thereof |
| EP1490483B1 (en) | 2001-04-19 | 2015-06-03 | The Scripps Research Institute | In vivo incorporation of unnatural amino acids |
| DK1578949T3 (da) * | 2002-10-16 | 2009-07-27 | Scripps Research Inst | Stedspecifik optagelse af keto-aminnosyrer hos proteiner |
| KR20050073559A (ko) | 2002-10-16 | 2005-07-14 | 더 스크립스 리서치 인스티튜트 | 당단백질 합성 |
| EP1583816A4 (en) | 2002-12-22 | 2007-06-13 | Scripps Research Inst | PROTEIN ARRAYS |
| CN103289960B (zh) | 2003-04-17 | 2017-04-26 | 斯克利普斯研究院 | 扩展真核生物遗传密码 |
| WO2005003294A2 (en) | 2003-06-18 | 2005-01-13 | The Scripps Research Institute | Unnatural reactive amino acid genetic code additions |
| WO2005007624A2 (en) | 2003-07-07 | 2005-01-27 | The Scripps Research Institute | Compositions of orthogonal glutamyl-trna and aminoacyl trna synthetase pairs and uses thereof |
| DE602004011789T2 (de) | 2003-07-07 | 2009-02-12 | The Scripps Research Institute, La Jolla | Zusammensetzungen der orthogonalen Lysyl-tRNA und Aminoacyl-tRNA Synthetase Paaren und ihre Verwendungen |
| WO2005007870A2 (en) | 2003-07-07 | 2005-01-27 | The Scripps Research Institute | COMPOSITIONS OF ORTHOGONAL LEUCYL-tRNA AND AMINOACYL-tRNA SYNTHETASE PAIRS AND USES THEREOF |
| WO2005038002A2 (en) | 2003-10-14 | 2005-04-28 | The Scripps Research Institute | Site-specific incorporation of redox active amino acids into proteins |
| BRPI0417801A (pt) | 2003-12-18 | 2007-04-10 | Scripps Research Inst | incorporação seletiva de 5-hidroxitriptofano em proteìnas de células mamìferas |
| AU2005248392A1 (en) | 2004-05-25 | 2005-12-08 | Irm, Llc | Site specific incorporation of heavy atom-containing unnatural amino acids into proteins for crystal structure determination |
| EP1797177A4 (en) | 2004-09-21 | 2008-07-09 | Scripps Research Inst | ADDITION OF PHOTOREGULATED AMINO ACIDS TO THE GENETIC CODE |
| EP1794323B1 (en) | 2004-09-21 | 2014-08-06 | The Scripps Research Institute | In vivo incorporation of alkynyl amino acids into proteins in eubacteria |
| JP2008513806A (ja) | 2004-09-22 | 2008-05-01 | ザ スクリップス リサーチ インスティテュート | Ｎｍｒ試験のための蛋白質の部位特異的標識 |
| EP1809758A4 (en) | 2004-10-20 | 2009-04-01 | Scripps Research Inst | LOCAL IN VIVO INSTALLATION OF N-ACETYLGALACTOSAMINE AMINO ACIDS IN EU BACTERIA |
| AU2005330514B2 (en) | 2004-10-27 | 2011-05-12 | The Scripps Research Institute | Orthogonal translation components for the in vivo incorporation of unnatural amino acids |
| CA2624290A1 (en) | 2005-10-12 | 2007-04-26 | Scripps Research Institute | Selective posttranslational modification of phage-displayed polypeptides |
| CA2638763A1 (en) | 2006-03-09 | 2007-09-13 | The Scripps Research Institute | System for the expression of orthogonal translation components in eubacterial host cells |
| JP5249194B2 (ja) | 2006-03-16 | 2013-07-31 | ザ スクリプス リサーチ インスティチュート | 非天然アミノ酸フェニルセレノシステインを含有するタンパク質の遺伝的にプログラムされた発現 |
-
2007
- 2007-09-20 CA CA002663052A patent/CA2663052A1/en not_active Abandoned
- 2007-09-20 RU RU2009110152/10A patent/RU2009110152A/ru not_active Application Discontinuation
- 2007-09-20 US US12/311,169 patent/US8114652B2/en active Active
- 2007-09-20 KR KR1020097007574A patent/KR20090074765A/ko not_active Ceased
- 2007-09-20 BR BRPI0716963-9A patent/BRPI0716963A2/pt not_active IP Right Cessation
- 2007-09-20 AU AU2007297610A patent/AU2007297610A1/en not_active Abandoned
- 2007-09-20 WO PCT/US2007/020459 patent/WO2008036392A2/en not_active Ceased
- 2007-09-20 EP EP07861356.9A patent/EP2052083B1/en not_active Not-in-force
- 2007-09-20 ES ES07861356.9T patent/ES2456331T3/es active Active
- 2007-09-20 JP JP2009529249A patent/JP5385143B2/ja not_active Expired - Fee Related
- 2007-09-20 PL PL07861356T patent/PL2052083T3/pl unknown
- 2007-09-20 PT PT78613569T patent/PT2052083E/pt unknown
- 2007-09-20 US US11/903,499 patent/US8114627B2/en active Active
- 2007-09-20 CN CN200780035189.6A patent/CN101516901B/zh not_active Expired - Fee Related
- 2007-09-20 MX MX2009002987A patent/MX2009002987A/es not_active Application Discontinuation
-
2009
- 2009-03-11 IL IL197531A patent/IL197531A0/en unknown
-
2011
- 2011-12-14 US US13/326,143 patent/US8361770B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US8114652B2 (en) | 2012-02-14 |
| EP2052083A2 (en) | 2009-04-29 |
| US8114627B2 (en) | 2012-02-14 |
| EP2052083B1 (en) | 2014-01-08 |
| CN101516901A (zh) | 2009-08-26 |
| PT2052083E (pt) | 2014-04-10 |
| US8361770B2 (en) | 2013-01-29 |
| BRPI0716963A2 (pt) | 2013-11-05 |
| RU2009110152A (ru) | 2010-10-27 |
| KR20090074765A (ko) | 2009-07-07 |
| CN101516901B (zh) | 2014-01-08 |
| PL2052083T3 (pl) | 2014-06-30 |
| ES2456331T3 (es) | 2014-04-22 |
| US20120184018A1 (en) | 2012-07-19 |
| CA2663052A1 (en) | 2008-03-27 |
| US20090286279A1 (en) | 2009-11-19 |
| US20080113407A1 (en) | 2008-05-15 |
| WO2008036392A2 (en) | 2008-03-27 |
| JP2010504096A (ja) | 2010-02-12 |
| EP2052083A4 (en) | 2010-03-24 |
| JP5385143B2 (ja) | 2014-01-08 |
| WO2008036392A9 (en) | 2008-05-22 |
| AU2007297610A1 (en) | 2008-03-27 |
| IL197531A0 (en) | 2009-12-24 |
| WO2008036392A3 (en) | 2008-12-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2009002987A (es) | Expresion geneticamente programada de proteinas selectivamente sulfatadas en eubacterias. | |
| MX2008011669A (es) | Expresion programada geneticamente de proteinas que contienen el aminoacido no natural fenilselenocisteina. | |
| MX2007003142A (es) | Incorporacion in vivo de alquinil aminoacidos a proteinas en eubacterias. | |
| WO2006110182A3 (en) | Orthogonal translation components for the in vivo incorporation of unnatural amino acids | |
| MX2009004043A (es) | Incorporacion genetica de aminoacidos no naturales a proteinas en celulas mamiferas. | |
| Mukai et al. | Highly reproductive Escherichia coli cells with no specific assignment to the UAG codon | |
| IL196893A (en) | Cell or cell line of vertebrate-containing amino acids trna synthase | |
| PT1991680E (pt) | Sistema para a expressão de componentes ortogonais de tradução em células hospedeiras eubacterianas | |
| BRPI0519568B8 (pt) | aminoacil-trna sintetase (rs), composições que compreendem a dita aminoacil-trna sintetase, célula de levedura, célula fúngica, célula não eucariótica, vetor que codifica uma rs, polinucleotídeo e ainda método para produzir um polipeptídeo em uma célula com um aminoácido selecionado em uma posição especificada | |
| MX2009002526A (es) | Transcripcion de tarn supresor en celulas de vertebrados. | |
| BRPI0411475A (pt) | adições de código genético de aminoácido reativo não natural | |
| EA201270758A1 (ru) | Мутанты fgf21 и их применение | |
| ATE542894T1 (de) | Ausweitung des eukaryotischen genetischen codes | |
| PL2311972T3 (pl) | Rekombinowane n-glikozylowane białka z komórek prokariotycznych | |
| MX2014001383A (es) | Colageno 7 y metodos relacionados. | |
| MX2008002149A (es) | Composiciones de arnt y sus usos. | |
| WO2002086075A3 (en) | Methods and composition for the production of orthoganal trna-aminoacyltrna synthetase pairs | |
| JP2010504096A5 (enExample) | ||
| PH12012500816A1 (en) | Modified oil encapsulating proteins and uses thereof | |
| WO2009034190A3 (en) | Affinity tag | |
| JP2008516637A5 (enExample) | ||
| WO2007130543A3 (en) | Method for producing stable mammalian cell lines producing high levels of recombinant proteins | |
| MX2022015376A (es) | Construcciones anti grupo de diferenciacion 93 (cd93) y usos de las mismas. | |
| WO2010114615A3 (en) | A facile system for encoding unnatural amino acids in mammalian cells | |
| WO2006019876A3 (en) | Production of fusion proteins by cell-free protein synthesis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |