MX2008012479A - Tratamiento de enfermedades neurodegenerativas. - Google Patents
Tratamiento de enfermedades neurodegenerativas.Info
- Publication number
- MX2008012479A MX2008012479A MX2008012479A MX2008012479A MX2008012479A MX 2008012479 A MX2008012479 A MX 2008012479A MX 2008012479 A MX2008012479 A MX 2008012479A MX 2008012479 A MX2008012479 A MX 2008012479A MX 2008012479 A MX2008012479 A MX 2008012479A
- Authority
- MX
- Mexico
- Prior art keywords
- neurodegenerative diseases
- treatment
- methods
- activity
- selenate
- Prior art date
Links
- 230000004770 neurodegeneration Effects 0.000 title abstract 2
- 208000015122 neurodegenerative disease Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 101000741929 Caenorhabditis elegans Serine/threonine-protein phosphatase 2A catalytic subunit Proteins 0.000 abstract 1
- 102000001267 GSK3 Human genes 0.000 abstract 1
- 108060006662 GSK3 Proteins 0.000 abstract 1
- 102000045595 Phosphoprotein Phosphatases Human genes 0.000 abstract 1
- 108700019535 Phosphoprotein Phosphatases Proteins 0.000 abstract 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- NFVJNJQRWPQVOA-UHFFFAOYSA-N n-[2-chloro-5-(trifluoromethyl)phenyl]-2-[3-(4-ethyl-5-ethylsulfanyl-1,2,4-triazol-3-yl)piperidin-1-yl]acetamide Chemical compound CCN1C(SCC)=NN=C1C1CN(CC(=O)NC=2C(=CC=C(C=2)C(F)(F)F)Cl)CCC1 NFVJNJQRWPQVOA-UHFFFAOYSA-N 0.000 abstract 1
- 230000026731 phosphorylation Effects 0.000 abstract 1
- 238000006366 phosphorylation reaction Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 102000013498 tau Proteins Human genes 0.000 abstract 1
- 108010026424 tau Proteins Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Enzymes And Modification Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78724006P | 2006-03-29 | 2006-03-29 | |
| PCT/AU2007/000391 WO2007109851A1 (en) | 2006-03-29 | 2007-03-29 | Treatment of neurodegenerative diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2008012479A true MX2008012479A (es) | 2009-08-13 |
Family
ID=38540722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2008012479A MX2008012479A (es) | 2006-03-29 | 2007-03-29 | Tratamiento de enfermedades neurodegenerativas. |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8920851B2 (https=) |
| EP (1) | EP2004204B1 (https=) |
| JP (1) | JP5542430B2 (https=) |
| KR (1) | KR101451439B1 (https=) |
| CN (1) | CN101478977B (https=) |
| AU (1) | AU2007231547B2 (https=) |
| BR (1) | BRPI0709033A2 (https=) |
| CA (1) | CA2644441C (https=) |
| DK (1) | DK2004204T3 (https=) |
| ES (1) | ES2394348T3 (https=) |
| MX (1) | MX2008012479A (https=) |
| NZ (2) | NZ571835A (https=) |
| RU (1) | RU2489155C2 (https=) |
| WO (1) | WO2007109851A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE024953T2 (en) | 2004-08-23 | 2016-02-29 | Yeda Res & Dev | Peptide inhibitors to mediate stress responses |
| ES2394348T3 (es) | 2006-03-29 | 2013-01-30 | Velacor Therapeutics Pty Ltd | Tratamiento de enfermedades neurodegenerativas con selenato |
| EP2012806A4 (en) * | 2006-04-24 | 2010-07-28 | Alltech Inc | METHOD AND COMPOSITIONS FOR MODIFYING CELL FUNCTIONS |
| US20100247679A1 (en) * | 2006-04-24 | 2010-09-30 | Alltech, Inc. | Methods and compositions for altering cell function |
| WO2008119109A1 (en) * | 2007-03-29 | 2008-10-09 | Velacor Therapeutics Pty Ltd | Treatment of neurological disorders |
| US8580776B2 (en) * | 2007-07-10 | 2013-11-12 | The Board Of Trustees Of The University Of Illinois | Compositions and methods for treating neurodegenerating diseases |
| WO2009039586A2 (en) * | 2007-09-28 | 2009-04-02 | Powmri Limited | Biomarkers for parkinson's disease |
| WO2009043106A1 (en) * | 2007-10-03 | 2009-04-09 | Velacor Therapeutics Pty Ltd | Inorganic selenium and angiogenesis |
| WO2009043116A1 (en) * | 2007-10-03 | 2009-04-09 | Velacor Therapeutics Pty Ltd | Methods and compositions for the treatment of phosphatase- related disorders |
| EP2219649A2 (en) * | 2007-11-22 | 2010-08-25 | Boehringer Ingelheim International Gmbh | Use of mnk inhibitors for the treatment of alzheimer's disease |
| JP5328244B2 (ja) * | 2008-07-07 | 2013-10-30 | 株式会社ニュージェン・ファーマ | 筋萎縮性側索硬化症治療剤 |
| AU2010304755A1 (en) * | 2009-10-09 | 2012-05-24 | Teva Pharmaceutical Industries, Ltd. | Use of rasagiline for the treatment of Progressive Supranuclear Palsy |
| EP2715350B1 (en) | 2011-05-23 | 2017-09-27 | Yeda Research and Development Co. Ltd. | Use of akt phosphorylation as a biomarker for prognosing neurodegenerative diseases and treating same |
| WO2016150403A1 (en) | 2015-03-26 | 2016-09-29 | Fujian Tiantai Medical Technology Co. Ltd | Method of diagnosis or treatment of neurological disorders with p75ecd and/or p75 |
| WO2019216589A1 (ko) * | 2018-05-09 | 2019-11-14 | 한국과학기술연구원 | 타우 관련 질환의 예방 또는 치료용 조성물 |
| BR112020026456A2 (pt) * | 2018-06-29 | 2021-03-23 | Rejuvenate Biomed | Combinação farmacêutica para o uso em doenças relacionadas com a idade e/ou degenerativas |
| JP7518852B2 (ja) | 2019-03-26 | 2024-07-18 | シアー， インコーポレイテッド | 生物流体からのタンパク質コロナ分析のための組成物、方法およびシステム、ならびにそれらの使用 |
| WO2023029210A1 (zh) * | 2021-08-31 | 2023-03-09 | 上海交通大学医学院附属瑞金医院 | Pp2a激动剂、清除和/或溶解衰老细胞和/或抑制细胞衰老的化合物用于治疗精神障碍 |
| WO2023057422A1 (en) * | 2021-10-06 | 2023-04-13 | Bayer Aktiengesellschaft | Universal buffer in methods for safe and rapid detection of pathogen infection |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8601915D0 (en) * | 1986-01-27 | 1986-03-05 | Efamol Ltd | Pharmaceutical compositions |
| JPH04247033A (ja) | 1991-02-04 | 1992-09-03 | Yoshitomi Pharmaceut Ind Ltd | 神経細胞壊死抑制剤 |
| US6746678B1 (en) * | 1991-02-22 | 2004-06-08 | Howard K. Shapiro | Method of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with medicaments |
| US5695752A (en) | 1992-09-11 | 1997-12-09 | The Regents Of The University Of California | Treating inflammation via the administration of specific sulfatase enzymes and/or sulfation inhibitor |
| EP0750511B1 (en) | 1994-03-16 | 2003-06-11 | The Regents Of The University Of California | Treating inflammation via the administration of specific sulfatase enzymes and/or sulfation inhibitor |
| US6524619B2 (en) | 2000-01-27 | 2003-02-25 | Chronorx, Inc. | Dosage forms useful for modifying conditions and functions associated with hearing loss and/or tinnitus |
| DE10059886A1 (de) | 2000-12-01 | 2002-06-20 | Basf Coatings Ag | Verwendung von wässrigen, physikalisch härtbaren Beschichtungsstoffen auf Polyurethanbasis als Haftgrundierung von Lackierungen |
| GB0202900D0 (en) * | 2002-02-07 | 2002-03-27 | Laxdale Ltd | Novel formulations of drugs |
| MXPA05001804A (es) | 2002-08-14 | 2005-05-27 | Vertex Pharma | Inhibidores de proteinas cinasas y usos de los mismos. |
| CN1812977A (zh) | 2003-04-30 | 2006-08-02 | 药物研发有限责任公司 | 取代羧酸 |
| AU2003904328A0 (en) | 2003-08-13 | 2003-08-28 | Garvan Institute Of Medical Research | Diagnosis and treatment of neurodegenerative disorders |
| WO2005023274A1 (en) | 2003-09-05 | 2005-03-17 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Treatment and prevention of inflammatory disease and mitochondrial dysfunction with high dose selenium |
| US20050142216A1 (en) | 2003-12-31 | 2005-06-30 | Rindlesbach Keith A. | Method for reversing Alzheimer dementia |
| TWI319708B (en) | 2005-10-14 | 2010-01-21 | Methods and compositions for altering cell fuction | |
| US20080004255A1 (en) | 2005-10-14 | 2008-01-03 | Alltech, Inc. | Methods and compositions for altering cell function |
| ES2394348T3 (es) | 2006-03-29 | 2013-01-30 | Velacor Therapeutics Pty Ltd | Tratamiento de enfermedades neurodegenerativas con selenato |
| CA2644445A1 (en) | 2006-03-29 | 2007-10-04 | Velacor Therapeutics Pty Ltd | Inorganic selenium for treatment of benign tumors |
-
2007
- 2007-03-29 ES ES07718638T patent/ES2394348T3/es active Active
- 2007-03-29 EP EP07718638A patent/EP2004204B1/en not_active Not-in-force
- 2007-03-29 CA CA2644441A patent/CA2644441C/en not_active Expired - Fee Related
- 2007-03-29 KR KR1020087026561A patent/KR101451439B1/ko not_active Expired - Fee Related
- 2007-03-29 NZ NZ571835A patent/NZ571835A/en not_active IP Right Cessation
- 2007-03-29 JP JP2009501780A patent/JP5542430B2/ja not_active Expired - Fee Related
- 2007-03-29 CN CN2007800122806A patent/CN101478977B/zh not_active Expired - Fee Related
- 2007-03-29 RU RU2008142514/15A patent/RU2489155C2/ru not_active IP Right Cessation
- 2007-03-29 NZ NZ596244A patent/NZ596244A/xx not_active IP Right Cessation
- 2007-03-29 DK DK07718638.5T patent/DK2004204T3/da active
- 2007-03-29 WO PCT/AU2007/000391 patent/WO2007109851A1/en not_active Ceased
- 2007-03-29 AU AU2007231547A patent/AU2007231547B2/en not_active Ceased
- 2007-03-29 BR BRPI0709033-1A patent/BRPI0709033A2/pt not_active IP Right Cessation
- 2007-03-29 MX MX2008012479A patent/MX2008012479A/es active IP Right Grant
- 2007-03-29 US US12/295,270 patent/US8920851B2/en not_active Expired - Fee Related
-
2013
- 2013-11-14 US US14/079,877 patent/US20140141104A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US8920851B2 (en) | 2014-12-30 |
| US20090169649A1 (en) | 2009-07-02 |
| DK2004204T3 (da) | 2013-01-07 |
| NZ596244A (en) | 2013-05-31 |
| WO2007109851A1 (en) | 2007-10-04 |
| NZ571835A (en) | 2011-11-25 |
| AU2007231547A1 (en) | 2007-10-04 |
| KR101451439B1 (ko) | 2014-10-16 |
| RU2008142514A (ru) | 2010-05-10 |
| CA2644441A1 (en) | 2007-10-04 |
| RU2489155C2 (ru) | 2013-08-10 |
| EP2004204B1 (en) | 2012-09-12 |
| ES2394348T3 (es) | 2013-01-30 |
| CA2644441C (en) | 2014-09-09 |
| JP2009532340A (ja) | 2009-09-10 |
| KR20090015038A (ko) | 2009-02-11 |
| EP2004204A4 (en) | 2010-06-02 |
| CN101478977B (zh) | 2013-03-27 |
| CN101478977A (zh) | 2009-07-08 |
| BRPI0709033A2 (pt) | 2011-06-21 |
| AU2007231547B2 (en) | 2012-07-12 |
| JP5542430B2 (ja) | 2014-07-09 |
| EP2004204A1 (en) | 2008-12-24 |
| US20140141104A1 (en) | 2014-05-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |