JP5542430B2 - 神経変性疾患の治療 - Google Patents

神経変性疾患の治療 Download PDF

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Publication number
JP5542430B2
JP5542430B2 JP2009501780A JP2009501780A JP5542430B2 JP 5542430 B2 JP5542430 B2 JP 5542430B2 JP 2009501780 A JP2009501780 A JP 2009501780A JP 2009501780 A JP2009501780 A JP 2009501780A JP 5542430 B2 JP5542430 B2 JP 5542430B2
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Prior art keywords
selenate
tau
pharmaceutically acceptable
acceptable salt
pp2a
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JP2009501780A
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Japanese (ja)
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JP2009532340A (ja
JP2009532340A5 (https=
Inventor
クリストファー ホベンス
ニオール コーコラン
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ベラコル セラピューティクス プロプライエタリー リミテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2009501780A 2006-03-29 2007-03-29 神経変性疾患の治療 Expired - Fee Related JP5542430B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78724006P 2006-03-29 2006-03-29
US60/787,240 2006-03-29
PCT/AU2007/000391 WO2007109851A1 (en) 2006-03-29 2007-03-29 Treatment of neurodegenerative diseases

Publications (3)

Publication Number Publication Date
JP2009532340A JP2009532340A (ja) 2009-09-10
JP2009532340A5 JP2009532340A5 (https=) 2010-05-13
JP5542430B2 true JP5542430B2 (ja) 2014-07-09

Family

ID=38540722

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009501780A Expired - Fee Related JP5542430B2 (ja) 2006-03-29 2007-03-29 神経変性疾患の治療

Country Status (14)

Country Link
US (2) US8920851B2 (https=)
EP (1) EP2004204B1 (https=)
JP (1) JP5542430B2 (https=)
KR (1) KR101451439B1 (https=)
CN (1) CN101478977B (https=)
AU (1) AU2007231547B2 (https=)
BR (1) BRPI0709033A2 (https=)
CA (1) CA2644441C (https=)
DK (1) DK2004204T3 (https=)
ES (1) ES2394348T3 (https=)
MX (1) MX2008012479A (https=)
NZ (2) NZ596244A (https=)
RU (1) RU2489155C2 (https=)
WO (1) WO2007109851A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005276117C1 (en) 2004-08-23 2013-04-18 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Peptide inhibitors for mediating stress responses
MX2008012479A (es) 2006-03-29 2009-08-13 Velacor Therapeutics Pty Ltd Tratamiento de enfermedades neurodegenerativas.
US20080107755A1 (en) * 2006-04-24 2008-05-08 Alltech, Inc. Methods and compositions for altering cell function
US20100247679A1 (en) * 2006-04-24 2010-09-30 Alltech, Inc. Methods and compositions for altering cell function
WO2008119109A1 (en) * 2007-03-29 2008-10-09 Velacor Therapeutics Pty Ltd Treatment of neurological disorders
US8580776B2 (en) * 2007-07-10 2013-11-12 The Board Of Trustees Of The University Of Illinois Compositions and methods for treating neurodegenerating diseases
WO2009039586A2 (en) * 2007-09-28 2009-04-02 Powmri Limited Biomarkers for parkinson's disease
WO2009043106A1 (en) * 2007-10-03 2009-04-09 Velacor Therapeutics Pty Ltd Inorganic selenium and angiogenesis
WO2009043116A1 (en) * 2007-10-03 2009-04-09 Velacor Therapeutics Pty Ltd Methods and compositions for the treatment of phosphatase- related disorders
WO2009065596A2 (en) * 2007-11-22 2009-05-28 Develogen Aktiengesellschaft Use of mnk inhibitors for the treatment of alzheimer's disease
JP5328244B2 (ja) * 2008-07-07 2013-10-30 株式会社ニュージェン・ファーマ 筋萎縮性側索硬化症治療剤
JP2013507352A (ja) * 2009-10-09 2013-03-04 テバ ファーマシューティカル インダストリーズ リミティド 進行性核上性麻痺の治療のためのラサギリンの使用
CA2836503C (en) 2011-05-23 2020-09-22 Yeda Research And Development Co. Ltd. Use of akt phosphorylation as a biomarker for prognosing neurodegenerative diseases and treating same
AU2016235685B2 (en) * 2015-03-26 2019-04-18 Shanghai Auzone Biological Technology Co., Ltd. Method of diagnosis or treatment of neurological disorders with p75ECD and/or p75
WO2019216589A1 (ko) * 2018-05-09 2019-11-14 한국과학기술연구원 타우 관련 질환의 예방 또는 치료용 조성물
KR102846956B1 (ko) * 2018-06-29 2025-08-14 리주베나떼 바이오메드 엔브이 노화-관련 질환 및/또는 퇴행성 질환에 사용하는 약제학적 결합물
JP7518852B2 (ja) 2019-03-26 2024-07-18 シアー, インコーポレイテッド 生物流体からのタンパク質コロナ分析のための組成物、方法およびシステム、ならびにそれらの使用
WO2023029210A1 (zh) * 2021-08-31 2023-03-09 上海交通大学医学院附属瑞金医院 Pp2a激动剂、清除和/或溶解衰老细胞和/或抑制细胞衰老的化合物用于治疗精神障碍
WO2023057422A1 (en) * 2021-10-06 2023-04-13 Bayer Aktiengesellschaft Universal buffer in methods for safe and rapid detection of pathogen infection

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8601915D0 (en) * 1986-01-27 1986-03-05 Efamol Ltd Pharmaceutical compositions
JPH04247033A (ja) 1991-02-04 1992-09-03 Yoshitomi Pharmaceut Ind Ltd 神経細胞壊死抑制剤
US6746678B1 (en) * 1991-02-22 2004-06-08 Howard K. Shapiro Method of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with medicaments
US5695752A (en) * 1992-09-11 1997-12-09 The Regents Of The University Of California Treating inflammation via the administration of specific sulfatase enzymes and/or sulfation inhibitor
WO1995024920A1 (en) 1994-03-16 1995-09-21 The Regents Of The University Of California Treating inflammation via the administration of specific sulfatase enzymes and/or sulfation inhibitor
US6524619B2 (en) * 2000-01-27 2003-02-25 Chronorx, Inc. Dosage forms useful for modifying conditions and functions associated with hearing loss and/or tinnitus
DE10059886A1 (de) * 2000-12-01 2002-06-20 Basf Coatings Ag Verwendung von wässrigen, physikalisch härtbaren Beschichtungsstoffen auf Polyurethanbasis als Haftgrundierung von Lackierungen
GB0202900D0 (en) * 2002-02-07 2002-03-27 Laxdale Ltd Novel formulations of drugs
AU2003262642B2 (en) * 2002-08-14 2010-06-17 Vertex Pharmaceuticals Incorporated Protein kinase inhibitors and uses thereof
BRPI0409914A (pt) 2003-04-30 2006-04-25 Inst For Pharm Discovery Inc ácidos carboxìlicos substituìdos
AU2003904328A0 (en) 2003-08-13 2003-08-28 Garvan Institute Of Medical Research Diagnosis and treatment of neurodegenerative disorders
WO2005023274A1 (en) 2003-09-05 2005-03-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Treatment and prevention of inflammatory disease and mitochondrial dysfunction with high dose selenium
US20050142216A1 (en) * 2003-12-31 2005-06-30 Rindlesbach Keith A. Method for reversing Alzheimer dementia
US20080004255A1 (en) * 2005-10-14 2008-01-03 Alltech, Inc. Methods and compositions for altering cell function
CN101073584B (zh) 2005-10-14 2012-10-10 全面技术公司 改变细胞功能的方法和组合物
MX2008012479A (es) 2006-03-29 2009-08-13 Velacor Therapeutics Pty Ltd Tratamiento de enfermedades neurodegenerativas.
EP2004205A4 (en) 2006-03-29 2010-06-09 Velacor Therapeutics Pty Ltd INORGANIC SELEN FOR THE TREATMENT OF GOOD TUMORS

Also Published As

Publication number Publication date
AU2007231547B2 (en) 2012-07-12
US20090169649A1 (en) 2009-07-02
KR101451439B1 (ko) 2014-10-16
EP2004204A1 (en) 2008-12-24
NZ596244A (en) 2013-05-31
US20140141104A1 (en) 2014-05-22
AU2007231547A1 (en) 2007-10-04
RU2008142514A (ru) 2010-05-10
EP2004204B1 (en) 2012-09-12
JP2009532340A (ja) 2009-09-10
NZ571835A (en) 2011-11-25
CN101478977A (zh) 2009-07-08
CN101478977B (zh) 2013-03-27
EP2004204A4 (en) 2010-06-02
KR20090015038A (ko) 2009-02-11
CA2644441A1 (en) 2007-10-04
MX2008012479A (es) 2009-08-13
US8920851B2 (en) 2014-12-30
CA2644441C (en) 2014-09-09
ES2394348T3 (es) 2013-01-30
DK2004204T3 (da) 2013-01-07
RU2489155C2 (ru) 2013-08-10
WO2007109851A1 (en) 2007-10-04
BRPI0709033A2 (pt) 2011-06-21

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