MX2007004987A - Nuevas formulaciones de tabletas de liberacion modificada para inhibidores de bomba de protones. - Google Patents
Nuevas formulaciones de tabletas de liberacion modificada para inhibidores de bomba de protones.Info
- Publication number
- MX2007004987A MX2007004987A MX2007004987A MX2007004987A MX2007004987A MX 2007004987 A MX2007004987 A MX 2007004987A MX 2007004987 A MX2007004987 A MX 2007004987A MX 2007004987 A MX2007004987 A MX 2007004987A MX 2007004987 A MX2007004987 A MX 2007004987A
- Authority
- MX
- Mexico
- Prior art keywords
- ppi
- proton pump
- modified release
- release tablet
- pump inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2813—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Una forma de dosificacion farmaceutica solida oral que comprende un inhibidor de bomba de proton sensible a acido (PPI) como un unico farmaco activo, que libera el PPI en dos pulsos separados, uno inmediato y otro con retardo. El PPI es formulado dentro de un material de nucleo en la forma de tabletas, las cuales estan recubiertas entre otras cosas con una combinacion de una capa modificadora de liberacion retardada y una capa controladora del tiempo de retardo que juntas alcanzan propiedades de liberacion beneficas. Las tabletas son ademas proporcionadas con una capa de revestimiento enterico. La solicitud tambien se relaciona con procesos para preparar las formas de dosificacion asi como a su uso en el tratamiento de enfermedades gastrointestinales.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62564904P | 2004-11-04 | 2004-11-04 | |
PCT/SE2005/001643 WO2006049565A1 (en) | 2004-11-04 | 2005-11-02 | New modified release tablet formulations for proton pump inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2007004987A true MX2007004987A (es) | 2007-06-14 |
Family
ID=36319458
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2007004987A MX2007004987A (es) | 2004-11-04 | 2005-11-02 | Nuevas formulaciones de tabletas de liberacion modificada para inhibidores de bomba de protones. |
Country Status (17)
Country | Link |
---|---|
US (1) | US20080003281A1 (es) |
EP (1) | EP1809262A4 (es) |
JP (1) | JP2008519070A (es) |
KR (1) | KR20070083956A (es) |
CN (1) | CN101094661A (es) |
AR (1) | AR052225A1 (es) |
AU (1) | AU2005301369A1 (es) |
BR (1) | BRPI0517954A (es) |
CA (1) | CA2584419A1 (es) |
IL (1) | IL182686A0 (es) |
MX (1) | MX2007004987A (es) |
NO (1) | NO20072257L (es) |
RU (1) | RU2007115544A (es) |
TW (1) | TW200624126A (es) |
UY (1) | UY29193A1 (es) |
WO (1) | WO2006049565A1 (es) |
ZA (1) | ZA200703111B (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR051654A1 (es) * | 2004-11-04 | 2007-01-31 | Astrazeneca Ab | Nuevas formulaciones de pellets de liberacion modificada para inhibidores de la bomba de protones |
EP1970056A1 (en) * | 2007-03-15 | 2008-09-17 | Polichem S.A. | Time-specific delayed/pulsatile release dosage forms |
CN101888828A (zh) * | 2007-07-27 | 2010-11-17 | 蒂宝制药公司 | 脉冲胃滞留剂型 |
ITFI20070253A1 (it) * | 2007-11-09 | 2009-05-10 | Valpharma Internat S P A | Formulazioni farmaceutiche per la somministrazione di ipp. |
WO2009137648A1 (en) * | 2008-05-09 | 2009-11-12 | Aptapharma, Inc. | Multilayer proton pump inhibitor tablets |
US20090280173A1 (en) * | 2008-05-09 | 2009-11-12 | Ishwar Chauhan | Multilayer Omeprazole Tablets |
WO2011078993A1 (en) * | 2009-12-21 | 2011-06-30 | Aptapharma, Inc. | Functionally-coated multilayer tablets |
US8563035B2 (en) | 2010-05-05 | 2013-10-22 | Sanovel Ilac Sanayi Ve Ticaret Anomin Sirketi | Oral tablet compositions of dexlansoprazole |
EP2384745A3 (en) | 2010-05-05 | 2012-01-18 | Sanovel Ilac Sanayi ve Ticaret A.S. | Modified release pharmaceutical compositions of dexlansoprazole |
EP2384747A3 (en) * | 2010-05-05 | 2012-01-18 | Sanovel Ilac Sanayi ve Ticaret A.S. | Oral Tablet Compositions Of Dexlansoprazole |
EP2384746A3 (en) * | 2010-05-05 | 2012-03-07 | Sanovel Ilac Sanayi ve Ticaret A.S. | Dual release oral tablet compositions of dexlansoprazole |
KR20140016260A (ko) * | 2011-02-03 | 2014-02-07 | 루핀 리미티드 | 베포타스틴의 경구용 방출 조절 약제 조성물 |
WO2012111024A1 (en) * | 2011-02-18 | 2012-08-23 | Suven Nishtaa Pharma Pvt Ltd | Pharmaceutical compositions of dexlansoprazole |
EP3288556A4 (en) | 2015-04-29 | 2018-09-19 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
CN104856971B (zh) * | 2015-05-15 | 2019-05-14 | 暨南大学 | 一种脉冲双释放制剂及其制备方法与应用 |
CN105012274A (zh) * | 2015-06-27 | 2015-11-04 | 上海信谊万象药业股份有限公司 | 一种奥美拉唑微片胶囊制剂及其制备方法 |
CN104940170A (zh) * | 2015-07-23 | 2015-09-30 | 浙江亚太药业股份有限公司 | 一种埃索美拉唑镁肠溶胶囊及其制备方法 |
US20170172960A1 (en) * | 2015-12-22 | 2017-06-22 | Imprimis Pharmaceuticals, Inc. | Pharmaceutical formulations for treating kidney stones and methods for fabricating and using thereof |
US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
KR101877350B1 (ko) * | 2016-10-28 | 2018-08-09 | 한미약품 주식회사 | 에스오메프라졸 함유 복합 캡슐제 및 그 제조방법 |
JP6336651B1 (ja) * | 2016-12-15 | 2018-06-06 | 大原薬品工業株式会社 | 化学的安定性が改善されたエソメプラゾール塩を含有する錠剤 |
WO2019030610A1 (en) * | 2017-08-11 | 2019-02-14 | Solutions In Innovative Research Pvt. Ltd. | PHARMACEUTICAL COMPOSITIONS WITH DUAL DIRECTLY COMPRESSIBLE MEDICAMENT RELEASE |
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IL75400A (en) * | 1984-06-16 | 1988-10-31 | Byk Gulden Lomberg Chem Fab | Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same |
US4704285A (en) * | 1985-11-18 | 1987-11-03 | The Dow Chemical Company | Sustained release compositions comprising hydroxypropyl cellulose ethers |
IT1230576B (it) * | 1988-10-20 | 1991-10-28 | Angeli Inst Spa | Formulazioni farmaceutiche per via orale a liberazione selettiva nel colon |
JPH07223970A (ja) * | 1994-02-10 | 1995-08-22 | Tanabe Seiyaku Co Ltd | 消化管内適所放出製剤 |
US5945124A (en) * | 1995-07-05 | 1999-08-31 | Byk Gulden Chemische Fabrik Gmbh | Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole |
US20050054682A1 (en) * | 1996-01-04 | 2005-03-10 | Phillips Jeffrey O. | Pharmaceutical compositions comprising substituted benzimidazoles and methods of using same |
SE9600072D0 (sv) * | 1996-01-08 | 1996-01-08 | Astra Ab | New oral formulation of two active ingredients II |
AU5179898A (en) * | 1996-11-06 | 1998-05-29 | Sharmatek, Inc. | Delayed delivery system for acid-sensitive drugs |
US5885616A (en) * | 1997-08-18 | 1999-03-23 | Impax Pharmaceuticals, Inc. | Sustained release drug delivery system suitable for oral administration |
SE9704870D0 (sv) * | 1997-12-22 | 1997-12-22 | Astra Ab | New pharmaceutical formulation I |
DE69939748D1 (de) * | 1998-11-02 | 2008-11-27 | Elan Pharma Int Ltd | Multipartikuläre zusammensetzung von methylphenidat mit modifizierter freisetzung |
US6632451B2 (en) * | 1999-06-04 | 2003-10-14 | Dexcel Pharma Technologies Ltd. | Delayed total release two pulse gastrointestinal drug delivery system |
EP1064938A1 (en) * | 1999-06-28 | 2001-01-03 | Sanofi-Synthelabo | Pharmaceutical dosage forms for controlled release producing at least a timed pulse |
EP1074249A1 (en) * | 1999-07-27 | 2001-02-07 | Jagotec Ag | A pharmaceutical tablet system for releasing at least one active substance during a release period subsequent to a no-release period |
ES2168043B1 (es) * | 1999-09-13 | 2003-04-01 | Esteve Labor Dr | Forma farmaceutica solida oral de liberacion modificada que contiene un compuesto de bencimidazol labil en medio acido. |
GB9923436D0 (en) * | 1999-10-04 | 1999-12-08 | American Home Prod | Pharmaceutical compositions |
US20030180352A1 (en) * | 1999-11-23 | 2003-09-25 | Patel Mahesh V. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US6627223B2 (en) * | 2000-02-11 | 2003-09-30 | Eurand Pharmaceuticals Ltd. | Timed pulsatile drug delivery systems |
US6749867B2 (en) * | 2000-11-29 | 2004-06-15 | Joseph R. Robinson | Delivery system for omeprazole and its salts |
CN1638740A (zh) * | 2001-09-28 | 2005-07-13 | 麦克内尔-Ppc股份有限公司 | 释出得到修饰的剂型 |
JP2003171277A (ja) * | 2001-12-07 | 2003-06-17 | Wyeth Lederle Japan Ltd | 薬物放出時間制御型固形製剤 |
CA2496044A1 (en) * | 2002-08-16 | 2004-02-26 | Themis Laboratories Private Limited | A process for manufacture of stable oral multiple units pharamceutical composition containing benzimidazoles |
US8487002B2 (en) * | 2002-10-25 | 2013-07-16 | Paladin Labs Inc. | Controlled-release compositions |
WO2004071374A2 (en) * | 2003-02-11 | 2004-08-26 | Torrent Pharmaceuticals Limited | Once a day orally administered pharmaceutical compositions |
US7670624B2 (en) * | 2004-01-29 | 2010-03-02 | Astella Pharma Inc. | Gastrointestinal-specific multiple drug release system |
MXPA06011820A (es) * | 2004-04-16 | 2006-12-15 | Santarus Inc | Combinacion de inhibidor de bomba de proton, agente regulador del ph y agente procinetico. |
-
2005
- 2005-10-31 AR ARP050104549A patent/AR052225A1/es not_active Application Discontinuation
- 2005-11-02 KR KR1020077010117A patent/KR20070083956A/ko not_active Application Discontinuation
- 2005-11-02 WO PCT/SE2005/001643 patent/WO2006049565A1/en active Application Filing
- 2005-11-02 CA CA002584419A patent/CA2584419A1/en not_active Abandoned
- 2005-11-02 EP EP05801796A patent/EP1809262A4/en not_active Withdrawn
- 2005-11-02 US US11/718,571 patent/US20080003281A1/en not_active Abandoned
- 2005-11-02 BR BRPI0517954-8A patent/BRPI0517954A/pt not_active Application Discontinuation
- 2005-11-02 MX MX2007004987A patent/MX2007004987A/es not_active Application Discontinuation
- 2005-11-02 CN CNA2005800458269A patent/CN101094661A/zh active Pending
- 2005-11-02 RU RU2007115544/15A patent/RU2007115544A/ru unknown
- 2005-11-02 JP JP2007540284A patent/JP2008519070A/ja active Pending
- 2005-11-02 AU AU2005301369A patent/AU2005301369A1/en not_active Abandoned
- 2005-11-04 UY UY29193A patent/UY29193A1/es not_active Application Discontinuation
- 2005-11-04 TW TW094138678A patent/TW200624126A/zh unknown
-
2007
- 2007-04-16 ZA ZA200703111A patent/ZA200703111B/xx unknown
- 2007-04-19 IL IL182686A patent/IL182686A0/en unknown
- 2007-05-02 NO NO20072257A patent/NO20072257L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1809262A4 (en) | 2012-09-05 |
JP2008519070A (ja) | 2008-06-05 |
CN101094661A (zh) | 2007-12-26 |
ZA200703111B (en) | 2009-09-30 |
RU2007115544A (ru) | 2008-12-10 |
TW200624126A (en) | 2006-07-16 |
AR052225A1 (es) | 2007-03-07 |
NO20072257L (no) | 2007-08-03 |
EP1809262A1 (en) | 2007-07-25 |
WO2006049565A1 (en) | 2006-05-11 |
BRPI0517954A (pt) | 2008-10-21 |
IL182686A0 (en) | 2007-09-20 |
KR20070083956A (ko) | 2007-08-24 |
CA2584419A1 (en) | 2006-05-11 |
US20080003281A1 (en) | 2008-01-03 |
AU2005301369A1 (en) | 2006-05-11 |
UY29193A1 (es) | 2006-06-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |