UA122762C2 - Пероральна композиція 9-[(2,2-диметилпропіламіно)-метил]-міноцикліну або його солі, тверда пресована дозована форма, композиція для ін'єкцій, застосування та спосіб приготування фармацевтичної композиції - Google Patents

Пероральна композиція 9-[(2,2-диметилпропіламіно)-метил]-міноцикліну або його солі, тверда пресована дозована форма, композиція для ін'єкцій, застосування та спосіб приготування фармацевтичної композиції

Info

Publication number
UA122762C2
UA122762C2 UAA201505310A UAA201505310A UA122762C2 UA 122762 C2 UA122762 C2 UA 122762C2 UA A201505310 A UAA201505310 A UA A201505310A UA A201505310 A UAA201505310 A UA A201505310A UA 122762 C2 UA122762 C2 UA 122762C2
Authority
UA
Ukraine
Prior art keywords
composition
dimethylpropylamino
minocycline
methyl
injections
Prior art date
Application number
UAA201505310A
Other languages
English (en)
Inventor
Джонстон Шон
Original Assignee
Паратек Фармасьютікалз, Інк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41114256&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA122762(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Паратек Фармасьютікалз, Інк. filed Critical Паратек Фармасьютікалз, Інк.
Publication of UA122762C2 publication Critical patent/UA122762C2/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Винахід стосується композиції для ін’єкцій, яка містить приблизно 90-110 мг 9-[(2,2-диметилпропіламіно)-метил]-міноцикліну та один або більше компонентів, вибраних з ліопротектора, де ліопротектор являє собою цукор, антиоксиданту, сполуки для регулювання рН, вибраної з соляної кислоти або гідроксиду натрію, та фармацевтично прийнятного носія, причому рН композиції знаходиться в межах від приблизно 4,0 до приблизно 4,5.
UAA201505310A 2008-03-28 2009-03-30 Пероральна композиція 9-[(2,2-диметилпропіламіно)-метил]-міноцикліну або його солі, тверда пресована дозована форма, композиція для ін'єкцій, застосування та спосіб приготування фармацевтичної композиції UA122762C2 (uk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4039808P 2008-03-28 2008-03-28

Publications (1)

Publication Number Publication Date
UA122762C2 true UA122762C2 (uk) 2021-01-06

Family

ID=41114256

Family Applications (2)

Application Number Title Priority Date Filing Date
UAA201012435A UA109627C2 (uk) 2008-03-28 2009-03-30 Композиції тетрациклінових сполук для орального введення та ін'єкцій
UAA201505310A UA122762C2 (uk) 2008-03-28 2009-03-30 Пероральна композиція 9-[(2,2-диметилпропіламіно)-метил]-міноцикліну або його солі, тверда пресована дозована форма, композиція для ін'єкцій, застосування та спосіб приготування фармацевтичної композиції

Family Applications Before (1)

Application Number Title Priority Date Filing Date
UAA201012435A UA109627C2 (uk) 2008-03-28 2009-03-30 Композиції тетрациклінових сполук для орального введення та ін'єкцій

Country Status (31)

Country Link
US (2) US9314475B2 (uk)
EP (3) EP3348258B1 (uk)
JP (7) JP2011515473A (uk)
KR (3) KR101746228B1 (uk)
CN (1) CN102046177B (uk)
AU (1) AU2009229174A1 (uk)
BR (2) BRPI0909211B8 (uk)
CA (2) CA2719751C (uk)
CL (1) CL2010000281A1 (uk)
CO (1) CO6300935A2 (uk)
CY (2) CY1120240T1 (uk)
DK (2) DK3348258T3 (uk)
EC (1) ECSP10010576A (uk)
ES (2) ES2674708T3 (uk)
HK (1) HK1257928A1 (uk)
HR (2) HRP20180836T1 (uk)
HU (2) HUE052201T2 (uk)
IL (1) IL208440A0 (uk)
LT (2) LT3348258T (uk)
MA (1) MA32275B1 (uk)
MX (1) MX2010010585A (uk)
NO (1) NO2271348T3 (uk)
NZ (1) NZ588428A (uk)
PL (2) PL2271348T3 (uk)
PT (2) PT2271348T (uk)
RU (1) RU2010144130A (uk)
SI (2) SI2271348T1 (uk)
TR (1) TR201806893T4 (uk)
UA (2) UA109627C2 (uk)
WO (1) WO2009120389A1 (uk)
ZA (1) ZA201007013B (uk)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009111064A2 (en) 2008-03-05 2009-09-11 Paratek Pharmaceuticals, Inc. Minocycline compounds and methods of use thereof
TW202332671A (zh) * 2008-05-23 2023-08-16 美商Ｐｒｔｋ Ｓｐｖ２公司 四環素化合物之甲苯磺酸鹽及同素異形體
CN102970992B (zh) 2010-05-12 2016-07-06 莱姆派克斯制药公司 四环素组合物
WO2017192516A1 (en) * 2016-05-02 2017-11-09 Paratek Pharmaceuticals, Inc. 9-aminomethyl minocycline compounds and methods of use thereof in urinary tract infection (uti) treatment
US10166912B2 (en) 2016-08-19 2019-01-01 Sl Corporation Automotive LED driving apparatus
EP3534908A4 (en) 2016-11-01 2020-05-27 Paratek Pharmaceuticals, Inc. 9-AMINOMETHYL-MINOCYCLINE COMPOUNDS AND USE THEREOF IN THE TREATMENT OF AMBULANTLY ACQUIRED BACTERIAL PNEUMONIA (CABP)
JP7466544B2 (ja) * 2018-09-04 2024-04-12 パラテック ファーマシューティカルズ，インコーポレイテッド テトラサイクリン化合物を使用してマイコバクテリア感染症を処置する方法
PT117254B (pt) 2021-05-26 2024-04-18 Hovione Farm S A Método de síntese de compostos 9-aminometil tetraciclinas

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2699054A (en) 1953-10-09 1955-01-11 Lloyd H Conover Tetracycline
US2712517A (en) 1954-03-03 1955-07-05 Bristol Lab Inc Production of tetracycline and substituted tetracyclines
US3019173A (en) 1956-06-04 1962-01-30 American Cyanamid Co Method for preparing tetracycline
US2990331A (en) 1956-11-23 1961-06-27 Pfizer & Co C Stable solutions of salts of tetracyclines for parenteral administration
US3005023A (en) 1957-04-05 1961-10-17 American Cyanamid Co Production of tetracycline
US2980584A (en) 1957-10-29 1961-04-18 Pfizer & Co C Parenteral magnesium oxytetracycline acetic or lactic acid carboxamide vehicle preparation
US2886595A (en) 1958-09-30 1959-05-12 Bristol Lab Inc Tetracycline recovery
US3062717A (en) 1958-12-11 1962-11-06 Pfizer & Co C Intramuscular calcium tetracycline acetic or lactic acid carboxamide vehicle preparation
US3019260A (en) 1959-05-13 1962-01-30 American Cyanamid Co Process for the catalytic reduction of 6-hydroxy hydronaphthacenes
FR1430859A (uk) 1960-05-23 1966-05-25
US3165531A (en) 1962-03-08 1965-01-12 Pfizer & Co C 13-substituted-6-deoxytetracyclines and process utilizing the same
US3301899A (en) 1963-11-27 1967-01-31 Bristol Myers Co Purification of tetracycline
US3454697A (en) 1965-06-08 1969-07-08 American Cyanamid Co Tetracycline antibiotic compositions for oral use
NL6607516A (uk) 1966-05-31 1967-12-01
DE1767891C3 (de) 1968-06-28 1980-10-30 Pfizer Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat
US3957980A (en) 1972-10-26 1976-05-18 Pfizer Inc. Doxycycline parenteral compositions
DE2442829A1 (de) 1974-09-06 1976-03-18 Merck Patent Gmbh Tetracyclische verbindungen und verfahren zu ihrer herstellung
US4018889A (en) 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
US4126680A (en) 1977-04-27 1978-11-21 Pfizer Inc. Tetracycline antibiotic compositions
US4837030A (en) 1987-10-06 1989-06-06 American Cyanamid Company Novel controlled release formulations of tetracycline compounds
US5494903A (en) 1991-10-04 1996-02-27 American Cyanamid Company 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
DE122006000058I1 (de) 1991-10-04 2007-01-18 Wyeth Corp 7-Substituierte-9-substituierte Amino-6-Demethyl-6-Deoxy-Tetracycline
US6465431B1 (en) * 1999-11-17 2002-10-15 Boston Life Sciences, Inc. Pharmaceutical compositions comprising troponin subunits, fragments and homologs thereof and methods of their use to inhibit angiogenesis
TR200000529T2 (tr) 1997-08-29 2000-08-21 Dsm N.V. İçinde eksipiyan olmayan granüller
KR100252699B1 (ko) * 1998-03-17 2000-12-01 강재헌 치주염 치료용 미노사이클린 조성물
WO2000028983A1 (en) 1998-11-18 2000-05-25 Collagenex Pharmaceuticals, Inc. Novel 4-dedimethy laminotetra cycline derivatives
US6448323B1 (en) 1999-07-09 2002-09-10 Bpsi Holdings, Inc. Film coatings and film coating compositions based on polyvinyl alcohol
WO2001047554A1 (fr) * 1999-12-28 2001-07-05 Chugai Seiyaku Kabushiki Kaisha Compositions d'anticorps stables et preparations pour injection
CN100473644C (zh) 2000-07-07 2009-04-01 塔夫茨大学信托人 9-取代的二甲胺四环素化合物
US7553828B2 (en) 2001-03-13 2009-06-30 Paratek Pharmaceuticals, Inc. 9-aminomethyl substituted minocycline compounds
JP2005506291A (ja) 2001-03-13 2005-03-03 パラテック ファーマシューティカルズ， インク． ７，９−置換テトラサイクリン化合物
WO2002072031A2 (en) * 2001-03-14 2002-09-19 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as synergistic antifungal agents
KR100982753B1 (ko) 2001-04-05 2010-09-16 콜라제넥스 파마슈티칼스, 인크 테트라사이클린 화합물 및 테트라사이클린 유도체의 전달조절
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
EP2329826A1 (en) * 2001-07-13 2011-06-08 Paratek Pharmaceuticals, Inc. Tetracyclines for the treatment of multiple sclerosis
EP2311451A1 (en) 2002-03-08 2011-04-20 Paratek Pharmaceuticals, Inc. Amino-methyl substituted tetracycline compounds
CN1390550A (zh) * 2002-07-25 2003-01-15 于航 盐酸米诺环素冻干粉针剂及其制备方法
EP2277504A1 (en) * 2002-10-24 2011-01-26 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
WO2004038000A2 (en) * 2002-10-24 2004-05-06 Paratek Pharmaceuticals, Inc. Methods of using substituted tetracycline compounds to modulate rna
US20040121003A1 (en) 2002-12-19 2004-06-24 Acusphere, Inc. Methods for making pharmaceutical formulations comprising deagglomerated microparticles
WO2004064728A2 (en) * 2003-01-16 2004-08-05 Paratek Pharmaceuticals, Inc. Use of specific tetracycline compounds in therapy
MXPA05008284A (es) * 2003-02-03 2006-03-21 Neopharm Inc Taxano y otros farmacos antineoplasicos encapsulados, liposomicos, estables, susceptibles de esterilizacion por filtracion.
WO2004078111A2 (en) * 2003-03-06 2004-09-16 Ranbaxy Laboratories Limited Extended release minocycline compositions and processes for their preparation
WO2004091513A2 (en) * 2003-04-10 2004-10-28 Paratek Pharmaceuticals, Inc. 9-aminomethyl substituted minocycline compounds
EA201001081A1 (ru) * 2003-07-09 2011-02-28 Пэрэтек Фамэсьютикэлс, Инк. Соединения тетрациклина, фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния у субъекта
EP2292590A3 (en) * 2003-07-09 2012-05-02 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
US20060287283A1 (en) 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
JP5010284B2 (ja) * 2004-01-15 2012-08-29 パラテック ファーマシューティカルズ インコーポレイテッド テトラサイクリン化合物の芳香族ａ環誘導体
GB2414668B (en) * 2004-06-03 2009-07-29 Dexcel Ltd Tetracycline modified release delivery system
PL1858488T5 (pl) * 2005-03-14 2024-01-03 Wyeth Llc Kompozycje tygecykliny i sposoby wytwarzania
EP1991236A2 (en) * 2006-01-24 2008-11-19 Paratek Pharmaceuticals, Inc. Methods of increasing oral bioavailability of tetracyclines
US20090246276A1 (en) * 2008-01-28 2009-10-01 Graham Jackson Pharmaceutical Compositions
WO2009111064A2 (en) * 2008-03-05 2009-09-11 Paratek Pharmaceuticals, Inc. Minocycline compounds and methods of use thereof

Also Published As

Publication number Publication date
JP2023144043A (ja) 2023-10-06
CA2984301C (en) 2020-10-27
JP2019196408A (ja) 2019-11-14
AU2009229174A1 (en) 2009-10-01
IL208440A0 (en) 2010-12-30
KR20110008057A (ko) 2011-01-25
BRPI0909211B1 (pt) 2020-08-25
EP3789030A1 (en) 2021-03-10
DK2271348T3 (en) 2018-06-14
PT2271348T (pt) 2018-04-16
US20100056638A1 (en) 2010-03-04
JP5940119B2 (ja) 2016-06-29
KR20180026799A (ko) 2018-03-13
JP2021167355A (ja) 2021-10-21
CO6300935A2 (es) 2011-07-21
SI3348258T1 (sl) 2020-12-31
ES2674708T3 (es) 2018-07-03
CL2010000281A1 (es) 2012-03-30
BRPI0909211A2 (pt) 2016-11-29
ES2836448T3 (es) 2021-06-25
WO2009120389A1 (en) 2009-10-01
JP2011515473A (ja) 2011-05-19
CA2719751A1 (en) 2009-10-01
JP2014221820A (ja) 2014-11-27
KR20160105532A (ko) 2016-09-06
JP6412521B2 (ja) 2018-10-24
CN102046177A (zh) 2011-05-04
CY1123382T1 (el) 2021-12-31
JP2018203778A (ja) 2018-12-27
BRPI0909211B8 (pt) 2021-05-25
RU2010144130A (ru) 2012-05-10
PL3348258T3 (pl) 2021-03-08
LT3348258T (lt) 2020-12-10
EP2271348A1 (en) 2011-01-12
TR201806893T4 (tr) 2018-06-21
JP6577645B2 (ja) 2019-09-18
SI2271348T1 (en) 2018-08-31
CY1120240T1 (el) 2019-07-10
EP3348258B1 (en) 2020-09-09
ZA201007013B (en) 2013-11-27
BR122020011180B1 (pt) 2021-03-23
EP2271348A4 (en) 2011-05-25
PL2271348T3 (pl) 2018-08-31
HRP20201883T1 (hr) 2021-01-22
US9314475B2 (en) 2016-04-19
HRP20180836T1 (hr) 2018-07-27
HK1257928A1 (zh) 2019-11-01
ECSP10010576A (es) 2010-12-30
CN102046177B (zh) 2012-12-19
KR101893740B1 (ko) 2018-08-30
UA109627C2 (uk) 2015-09-25
DK3348258T3 (da) 2020-12-07
HUE052201T2 (hu) 2021-04-28
EP2271348B1 (en) 2018-03-28
KR101746228B1 (ko) 2017-06-12
MX2010010585A (es) 2010-11-09
JP2016145260A (ja) 2016-08-12
LT2271348T (lt) 2018-06-25
US20160279151A1 (en) 2016-09-29
KR101835574B1 (ko) 2018-03-08
PT3348258T (pt) 2020-11-25
WO2009120389A8 (en) 2009-12-30
EP3348258A1 (en) 2018-07-18
NZ588428A (en) 2012-08-31
HUE038257T2 (hu) 2018-10-29
CA2719751C (en) 2018-01-02
MA32275B1 (fr) 2011-05-02
BR122020011180B8 (pt) 2021-07-27
CA2984301A1 (en) 2009-10-01
NO2271348T3 (uk) 2018-08-25

Similar Documents

Publication Publication Date Title
UA122762C2 (uk) Пероральна композиція 9-[(2,2-диметилпропіламіно)-метил]-міноцикліну або його солі, тверда пресована дозована форма, композиція для ін'єкцій, застосування та спосіб приготування фармацевтичної композиції
WO2011124953A3 (en) Controlled release pharmaceutical compositions of tapentadol
WO2008069941A3 (en) Modified release ibuprofen solid oral dosage form
EA200901277A1 (ru) Фармацевтические составы, содержащие пропиленгликольгидрат дапаглифлозина
EA201100313A1 (ru) Способ доставки фармацевтической композиции пациенту, нуждающемуся в этом
NZ597260A (en) Formulations for parenteral delivery of compounds and uses thereof comprising methylnaltrexone
MX2011012122A (es) Derivados de tiofeno.
MX2011012627A (es) Derivados aminobutiricos sustituidos como inhibidores de nepralisina.
TR201907729T4 (tr) Bir anti-çekirdekleştirici ajan içeren farmasötik bileşim.
UA106057C2 (uk) Спосіб одержання сполук дигідроінденаміду, фармацевтична композиція, що містить дані сполуки, та їх застосування як інгібітора протеїнкінази
WO2007145991A3 (en) Anti-inflammatory and analgesic compositions and related methods
EP1750862A4 (en) PHARMACEUTICAL COMPOSITION CONTAINING IRBESARTAN
EA201190127A1 (ru) Фармацевтические составы нитазоксанида с контролируемым высвобождением
MX2010010647A (es) Proceso para preparar formulaciones de dabigatran para administracion oral.
RS54543B1 (en) Fast acting gastric acid secretion inhibitor
UA105229C2 (uk) Фармацевтичний склад
MY151295A (en) Pyrimidyl indoline compound
NZ587202A (en) Methods for measuring a patient response upon administration of a drug and compositions thereof
HK1072195A1 (en) Pharmaceutical preparation containing a benzimidazole compound mixed with microcrystalline celluloseand a method for its preparation
UA93393C2 (uk) 1,3-діоксанкарбонові кислоти
NO20074933L (no) Farmasoytisk sammensetning som innbefatter et indolylmaleimidderivat
UA103500C2 (uk) Сульфоксимінзаміщені анілінопіримідинові похідні як cdk-інгібітори, їх одержання й застосування як лікарських засобів
WO2010044097A3 (en) Novel dosage form of paliperidone and process for preparing the same
WO2011083402A3 (en) Immediate release compositions of acid labile drugs
CA2643400A1 (en) Camptothecin derivatives and their uses