CY1120240T1 - Απο του στοματος χορηγουμενο παρασκευασμα δισκιου ενωσης τετρακυκλινης - Google Patents

Απο του στοματος χορηγουμενο παρασκευασμα δισκιου ενωσης τετρακυκλινης

Info

Publication number
CY1120240T1
CY1120240T1 CY20181100542T CY181100542T CY1120240T1 CY 1120240 T1 CY1120240 T1 CY 1120240T1 CY 20181100542 T CY20181100542 T CY 20181100542T CY 181100542 T CY181100542 T CY 181100542T CY 1120240 T1 CY1120240 T1 CY 1120240T1
Authority
CY
Cyprus
Prior art keywords
tablet preparation
oral tetracycline
component tablet
tetracycline component
oral
Prior art date
Application number
CY20181100542T
Other languages
English (en)
Inventor
Sean Johnston
Original Assignee
Paratek Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41114256&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1120240(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Paratek Pharmaceuticals, Inc. filed Critical Paratek Pharmaceuticals, Inc.
Publication of CY1120240T1 publication Critical patent/CY1120240T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Περιγράφονται ενέσιμα και από του στόματος χορηγούμενα παρασκευάσματα ένωσης τετρακυκλίνης. Σε μία υλοποίηση, η εφεύρεση αφορά ένα από του στόματος χορηγούμενο παρασκεύασμα μίας ένωσης 9-αμινομεθυλοτετρακυκλίνης, ή ενός άλατος αυτής, σε μορφή δισκίου ή κάψουλας. Τα παρασκευάσματα μπορούν να χρησιμοποιούνται στην αγωγή μολύνσεων.
CY20181100542T 2008-03-28 2018-05-23 Απο του στοματος χορηγουμενο παρασκευασμα δισκιου ενωσης τετρακυκλινης CY1120240T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4039808P 2008-03-28 2008-03-28
PCT/US2009/001973 WO2009120389A1 (en) 2008-03-28 2009-03-30 Oral and injectable formulations of tetracycline compounds

Publications (1)

Publication Number Publication Date
CY1120240T1 true CY1120240T1 (el) 2019-07-10

Family

ID=41114256

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20181100542T CY1120240T1 (el) 2008-03-28 2018-05-23 Απο του στοματος χορηγουμενο παρασκευασμα δισκιου ενωσης τετρακυκλινης
CY20201100908T CY1123382T1 (el) 2008-03-28 2020-09-24 Απο του στοματος και ενεσιμα και σκευασματα ενωσεων τετρακυκλινης

Family Applications After (1)

Application Number Title Priority Date Filing Date
CY20201100908T CY1123382T1 (el) 2008-03-28 2020-09-24 Απο του στοματος και ενεσιμα και σκευασματα ενωσεων τετρακυκλινης

Country Status (31)

Country Link
US (2) US9314475B2 (el)
EP (3) EP3789030A1 (el)
JP (7) JP2011515473A (el)
KR (3) KR101893740B1 (el)
CN (1) CN102046177B (el)
AU (1) AU2009229174A1 (el)
BR (2) BR122020011180B8 (el)
CA (2) CA2719751C (el)
CL (1) CL2010000281A1 (el)
CO (1) CO6300935A2 (el)
CY (2) CY1120240T1 (el)
DK (2) DK3348258T3 (el)
EC (1) ECSP10010576A (el)
ES (2) ES2674708T3 (el)
HK (1) HK1257928A1 (el)
HR (2) HRP20180836T1 (el)
HU (2) HUE038257T2 (el)
IL (1) IL208440A0 (el)
LT (2) LT2271348T (el)
MA (1) MA32275B1 (el)
MX (1) MX2010010585A (el)
NO (1) NO2271348T3 (el)
NZ (1) NZ588428A (el)
PL (2) PL2271348T3 (el)
PT (2) PT2271348T (el)
RU (1) RU2010144130A (el)
SI (2) SI3348258T1 (el)
TR (1) TR201806893T4 (el)
UA (2) UA109627C2 (el)
WO (1) WO2009120389A1 (el)
ZA (1) ZA201007013B (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009111064A2 (en) 2008-03-05 2009-09-11 Paratek Pharmaceuticals, Inc. Minocycline compounds and methods of use thereof
TWI585071B (zh) * 2008-05-23 2017-06-01 派洛泰克藥物股份有限公司 四環素化合物之甲苯磺酸鹽及同素異形體
DK2568987T3 (en) 2010-05-12 2017-02-20 Rempex Pharmaceuticals Inc Tetracycline COMPOSITIONS
MX2018013271A (es) * 2016-05-02 2019-03-28 Paratek Pharm Innc Compuestos 9-aminometil minociclina y metodos para utilizarlos en el tratamiento de infeccion de vias urinarias (ivu).
US10166912B2 (en) 2016-08-19 2019-01-01 Sl Corporation Automotive LED driving apparatus
SG10201913599RA (en) 2016-11-01 2020-02-27 Paratek Pharm Innc 9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (cabp)
MA53564A (fr) * 2018-09-04 2021-07-14 Paratek Pharm Innc Procédés de traitement d'infections mycobactériennes à l'aide de composés de tétracycline
PT117254B (pt) 2021-05-26 2024-04-18 Hovione Farm S A Método de síntese de compostos 9-aminometil tetraciclinas

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2699054A (en) * 1953-10-09 1955-01-11 Lloyd H Conover Tetracycline
US2712517A (en) * 1954-03-03 1955-07-05 Bristol Lab Inc Production of tetracycline and substituted tetracyclines
US3019173A (en) * 1956-06-04 1962-01-30 American Cyanamid Co Method for preparing tetracycline
US2990331A (en) 1956-11-23 1961-06-27 Pfizer & Co C Stable solutions of salts of tetracyclines for parenteral administration
US3005023A (en) * 1957-04-05 1961-10-17 American Cyanamid Co Production of tetracycline
US2980584A (en) 1957-10-29 1961-04-18 Pfizer & Co C Parenteral magnesium oxytetracycline acetic or lactic acid carboxamide vehicle preparation
US2886595A (en) * 1958-09-30 1959-05-12 Bristol Lab Inc Tetracycline recovery
US3062717A (en) 1958-12-11 1962-11-06 Pfizer & Co C Intramuscular calcium tetracycline acetic or lactic acid carboxamide vehicle preparation
US3019260A (en) * 1959-05-13 1962-01-30 American Cyanamid Co Process for the catalytic reduction of 6-hydroxy hydronaphthacenes
FR1430859A (el) * 1960-05-23 1966-05-25
US3165531A (en) 1962-03-08 1965-01-12 Pfizer & Co C 13-substituted-6-deoxytetracyclines and process utilizing the same
US3301899A (en) * 1963-11-27 1967-01-31 Bristol Myers Co Purification of tetracycline
US3454697A (en) 1965-06-08 1969-07-08 American Cyanamid Co Tetracycline antibiotic compositions for oral use
NL6607516A (el) 1966-05-31 1967-12-01
DE1767891C3 (de) 1968-06-28 1980-10-30 Pfizer Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat
US3957980A (en) 1972-10-26 1976-05-18 Pfizer Inc. Doxycycline parenteral compositions
DE2442829A1 (de) 1974-09-06 1976-03-18 Merck Patent Gmbh Tetracyclische verbindungen und verfahren zu ihrer herstellung
US4018889A (en) 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
US4126680A (en) 1977-04-27 1978-11-21 Pfizer Inc. Tetracycline antibiotic compositions
US4837030A (en) * 1987-10-06 1989-06-06 American Cyanamid Company Novel controlled release formulations of tetracycline compounds
US5494903A (en) * 1991-10-04 1996-02-27 American Cyanamid Company 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
ES2168254T3 (es) 1991-10-04 2002-06-16 American Cyanamid Co Nuevas 7-sustituidas-9-(amino sustituido)-6-desmetil-6-desoxitetraciclinas.
US6465431B1 (en) * 1999-11-17 2002-10-15 Boston Life Sciences, Inc. Pharmaceutical compositions comprising troponin subunits, fragments and homologs thereof and methods of their use to inhibit angiogenesis
TR200000529T2 (tr) 1997-08-29 2000-08-21 Dsm N.V. İçinde eksipiyan olmayan granüller
KR100252699B1 (ko) * 1998-03-17 2000-12-01 강재헌 치주염 치료용 미노사이클린 조성물
KR100701635B1 (ko) 1998-11-18 2007-03-30 콜라제넥스 파마슈티칼스, 인크 신규한 4-데디메틸아미노테트라시클린 유도체
US6448323B1 (en) 1999-07-09 2002-09-10 Bpsi Holdings, Inc. Film coatings and film coating compositions based on polyvinyl alcohol
US20030124119A1 (en) * 1999-12-28 2003-07-03 Tadao Yamazaki Stable antibody compositions and injection preparations
WO2002004406A2 (en) * 2000-07-07 2002-01-17 Trustees Of Tufts College 9-substituted minocycline compounds
US7553828B2 (en) * 2001-03-13 2009-06-30 Paratek Pharmaceuticals, Inc. 9-aminomethyl substituted minocycline compounds
CZ20032780A3 (cs) 2001-03-13 2004-01-14 Paratek Pharmaceuticals, Inc. 7,9- Substituované tetracyklinové sloučeniny
WO2002072031A2 (en) * 2001-03-14 2002-09-19 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as synergistic antifungal agents
AU2002256092C1 (en) * 2001-04-05 2009-10-15 Collagenex Pharmaceuticals, Inc. Controlled delivery of tetracycline compounds and tetracycline derivatives
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
WO2003005971A2 (en) * 2001-07-13 2003-01-23 Paratek Pharmaceuticals, Inc. Tetracycline compounds having target therapeutic activities
KR101093842B1 (ko) * 2002-03-08 2011-12-13 파라테크 파마슈티컬스, 인크. 아미노-메틸 치환된 테트라시클린 화합물
CN1390550A (zh) * 2002-07-25 2003-01-15 于航 盐酸米诺环素冻干粉针剂及其制备方法
JP4686189B2 (ja) * 2002-10-24 2011-05-18 パラテック ファーマシューティカルズ インコーポレイテッド Ｒｎａを調節するための置換テトラサイクリン化合物の使用方法
WO2004038001A2 (en) * 2002-10-24 2004-05-06 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
US20040121003A1 (en) 2002-12-19 2004-06-24 Acusphere, Inc. Methods for making pharmaceutical formulations comprising deagglomerated microparticles
WO2004064728A2 (en) * 2003-01-16 2004-08-05 Paratek Pharmaceuticals, Inc. Use of specific tetracycline compounds in therapy
EP1596825A2 (en) * 2003-02-03 2005-11-23 Neopharm, Inc. Stable sterile filterable liposomal encapsulated taxane and other antineoplastic drugs
WO2004078111A2 (en) * 2003-03-06 2004-09-16 Ranbaxy Laboratories Limited Extended release minocycline compositions and processes for their preparation
WO2004091513A2 (en) * 2003-04-10 2004-10-28 Paratek Pharmaceuticals, Inc. 9-aminomethyl substituted minocycline compounds
EP1656341A1 (en) * 2003-07-09 2006-05-17 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
EA201001081A1 (ru) * 2003-07-09 2011-02-28 Пэрэтек Фамэсьютикэлс, Инк. Соединения тетрациклина, фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния у субъекта
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
EP1716101A1 (en) * 2004-01-15 2006-11-02 Paratek Pharmaceuticals, Inc. Aromatic a-ring derivatives of tetracycline compounds
GB2414668B (en) * 2004-06-03 2009-07-29 Dexcel Ltd Tetracycline modified release delivery system
ES2434944T5 (es) * 2005-03-14 2022-10-20 Wyeth Llc Composiciones de tigeciclina y procedimientos de preparación
EP1991236A2 (en) * 2006-01-24 2008-11-19 Paratek Pharmaceuticals, Inc. Methods of increasing oral bioavailability of tetracyclines
US20090246276A1 (en) * 2008-01-28 2009-10-01 Graham Jackson Pharmaceutical Compositions
WO2009111064A2 (en) * 2008-03-05 2009-09-11 Paratek Pharmaceuticals, Inc. Minocycline compounds and methods of use thereof

Also Published As

Publication number Publication date
HRP20201883T1 (hr) 2021-01-22
PT3348258T (pt) 2020-11-25
NZ588428A (en) 2012-08-31
JP2011515473A (ja) 2011-05-19
ES2674708T3 (es) 2018-07-03
JP2021167355A (ja) 2021-10-21
BR122020011180B1 (pt) 2021-03-23
JP2019196408A (ja) 2019-11-14
WO2009120389A8 (en) 2009-12-30
KR20110008057A (ko) 2011-01-25
HUE038257T2 (hu) 2018-10-29
JP2018203778A (ja) 2018-12-27
KR20180026799A (ko) 2018-03-13
UA122762C2 (uk) 2021-01-06
CA2984301C (en) 2020-10-27
JP6577645B2 (ja) 2019-09-18
CY1123382T1 (el) 2021-12-31
CO6300935A2 (es) 2011-07-21
SI2271348T1 (en) 2018-08-31
ES2836448T3 (es) 2021-06-25
EP3789030A1 (en) 2021-03-10
CN102046177B (zh) 2012-12-19
CN102046177A (zh) 2011-05-04
RU2010144130A (ru) 2012-05-10
CA2719751C (en) 2018-01-02
JP2023144043A (ja) 2023-10-06
JP5940119B2 (ja) 2016-06-29
DK3348258T3 (da) 2020-12-07
BRPI0909211B1 (pt) 2020-08-25
UA109627C2 (uk) 2015-09-25
BRPI0909211A2 (pt) 2016-11-29
JP2016145260A (ja) 2016-08-12
US20160279151A1 (en) 2016-09-29
EP2271348A4 (en) 2011-05-25
EP3348258B1 (en) 2020-09-09
LT3348258T (lt) 2020-12-10
SI3348258T1 (sl) 2020-12-31
IL208440A0 (en) 2010-12-30
HRP20180836T1 (hr) 2018-07-27
TR201806893T4 (tr) 2018-06-21
JP2014221820A (ja) 2014-11-27
JP6412521B2 (ja) 2018-10-24
BRPI0909211B8 (pt) 2021-05-25
KR101746228B1 (ko) 2017-06-12
EP2271348B1 (en) 2018-03-28
LT2271348T (lt) 2018-06-25
KR101893740B1 (ko) 2018-08-30
HK1257928A1 (zh) 2019-11-01
PT2271348T (pt) 2018-04-16
EP2271348A1 (en) 2011-01-12
PL2271348T3 (pl) 2018-08-31
HUE052201T2 (hu) 2021-04-28
KR101835574B1 (ko) 2018-03-08
KR20160105532A (ko) 2016-09-06
NO2271348T3 (el) 2018-08-25
PL3348258T3 (pl) 2021-03-08
US20100056638A1 (en) 2010-03-04
CA2984301A1 (en) 2009-10-01
CL2010000281A1 (es) 2012-03-30
DK2271348T3 (en) 2018-06-14
MX2010010585A (es) 2010-11-09
AU2009229174A1 (en) 2009-10-01
WO2009120389A1 (en) 2009-10-01
MA32275B1 (fr) 2011-05-02
EP3348258A1 (en) 2018-07-18
US9314475B2 (en) 2016-04-19
ECSP10010576A (es) 2010-12-30
CA2719751A1 (en) 2009-10-01
ZA201007013B (en) 2013-11-27
BR122020011180B8 (pt) 2021-07-27

Similar Documents

Publication Publication Date Title
CY1120240T1 (el) Απο του στοματος χορηγουμενο παρασκευασμα δισκιου ενωσης τετρακυκλινης
CY1124007T1 (el) Στοματικες δοσολογικες μορφες παρατεταμενης απελευθερωσης τοφασιτινιμπης
CY1122786T1 (el) Δοσολογικα σχηματα για ενωσεις κατηγοριας εχινοκανδινης
CY1118936T1 (el) Φαρμακευτικες συνθεσεις και μεθοδοι για την αγωγη ή την προληψη νοσου σχετιζομενης με οξαλικο
CY1117331T1 (el) Αντισωματα προσδεσης στην εξωκυτταρικη περιοχη 4 του ανθρωπινου csf1r και η χρηση αυτων
CY1118813T1 (el) Φαρμακευτικες συνθεσεις συν-κρυσταλλων τραμαδολης και κοξιμπων
CY1121315T1 (el) Απο του στοματος χορηγουμενες συνθεσεις της δεφερασιροξης
CY1122483T1 (el) Λυοφιλοποιημενες παρασκευες μελφαλανης φλουφεναμιδης
DOP2017000306A (es) Formulaciones farmacéuticas que contienen tenofovir y emtricitabina
CY1113231T1 (el) Απαραβιαστες φαρμακοτεχνικες μορφες δοσολογιας απο του στοματος περιλαμβανουσες ενα οπιουχο αναλγητικο
CY1115254T1 (el) Φαρμακευτικα διαλυματα, διαδικασιες για την παρασκευη τους και θεραπευτικες χρησεις
EA201100971A1 (ru) Производные пиримидининдола для лечения злокачественного новообразования
EA201691695A1 (ru) Терапевтические композиции, содержащие рилпивирин hcl и тенофовира дизопроксилфумарат
CY1115381T1 (el) Διενυδρη υδροχλωρικη ναλμεφαινη
CY1111442T1 (el) Ενωσεις πιπεριδινης και χρησεις αυτων
CY1120852T1 (el) Φαρμακευτικη συνθεση η οποια περιλαμβανει ιβουπροφαινη, τραμαδολη και ενα βασικο αμινοξυ, μεθοδος παρασκευης αυτης και χρηση της ιδιας
TR201906685T4 (tr) Kristalin macitentan içeren farmasötik bileşim.
CY1120820T1 (el) Νεα συνθεση αλβαιντανυλης για την αγωγη του οξεος πονου
CY1108711T1 (el) Συνθεσεις βενζοθειαζολιου και η χρηση αυτων
EA201390417A1 (ru) Антидиабетические твердые фармацевтические композиции
EA201691034A1 (ru) Композиции в твердой форме с замедленным высвобождением для перорального введения
EA201391384A1 (ru) Комплексы галлия, фармацевтические композиции и способы применения
TR201721700A2 (tr) Saksagli̇pti̇ni̇n ağizda dağilan formülasyonlari
TR200903014A1 (tr) Oral yolla dağılan dimebolin bileşimleri.
CY1125762T1 (el) Νεα απο του στοματος σκευασματα βελινοστατης