MX18879A - Analogos de la prostaglandina de amida heterociclica substituida con 7-oxabicicloheptilo. - Google Patents

Analogos de la prostaglandina de amida heterociclica substituida con 7-oxabicicloheptilo.

Info

Publication number
MX18879A
MX18879A MX1887989A MX1887989A MX18879A MX 18879 A MX18879 A MX 18879A MX 1887989 A MX1887989 A MX 1887989A MX 1887989 A MX1887989 A MX 1887989A MX 18879 A MX18879 A MX 18879A
Authority
MX
Mexico
Prior art keywords
oxabicicloheptilo
heterociclica
prostaglandina
amida
analogs
Prior art date
Application number
MX1887989A
Other languages
English (en)
Spanish (es)
Inventor
Philip M Sher
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of MX18879A publication Critical patent/MX18879A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
MX1887989A 1988-12-23 1989-12-22 Analogos de la prostaglandina de amida heterociclica substituida con 7-oxabicicloheptilo. MX18879A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28882688A 1988-12-23 1988-12-23

Publications (1)

Publication Number Publication Date
MX18879A true MX18879A (es) 1994-01-31

Family

ID=23108806

Family Applications (1)

Application Number Title Priority Date Filing Date
MX1887989A MX18879A (es) 1988-12-23 1989-12-22 Analogos de la prostaglandina de amida heterociclica substituida con 7-oxabicicloheptilo.

Country Status (18)

Country Link
EP (1) EP0374952A3 (en:Method)
JP (1) JPH02221278A (en:Method)
KR (1) KR900009639A (en:Method)
CN (1) CN1031059C (en:Method)
AU (1) AU617569B2 (en:Method)
CA (1) CA2006355A1 (en:Method)
DD (1) DD286359A5 (en:Method)
DK (1) DK172411B1 (en:Method)
FI (1) FI97230C (en:Method)
HU (1) HUT54161A (en:Method)
IL (1) IL92837A (en:Method)
MX (1) MX18879A (en:Method)
NO (1) NO175258C (en:Method)
NZ (1) NZ231962A (en:Method)
PH (1) PH27413A (en:Method)
PL (2) PL165147B1 (en:Method)
PT (1) PT92768B (en:Method)
ZA (1) ZA899868B (en:Method)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ232897A (en) * 1989-04-03 1992-12-23 Squibb & Sons Inc Interphenylene 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogues, preparation and pharmaceutical compositions thereof
DE4035851A1 (de) * 1990-11-10 1992-05-14 Bayer Ag Substituierte aminosaeureamid-derivate deren herstellung und verwendung
US4977174A (en) * 1989-06-12 1990-12-11 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane imidazole prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease
NZ233600A (en) * 1989-06-12 1992-10-28 Squibb & Sons Inc 7-oxabicyclo(2.2.1)heptane imidazole prostaglandin analogs and pharmaceutical compositions
US5290799A (en) * 1990-09-19 1994-03-01 E. R. Squibb & Sons, Inc. 7-oxabicycloheptyl substituted heterocyclic thioamide prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease
US5550248A (en) * 1990-11-29 1996-08-27 E.R. Squibb & Sons, Inc. Substituted stryl heterocyclic amido prostaglandin analogs
DE4102042A1 (de) * 1991-01-24 1992-07-30 Bayer Ag Substituierte aminosaeureamid-derivate deren herstellung und verwendung als fungizide
US5135939A (en) * 1991-01-28 1992-08-04 E. R. Squibb & Sons, Inc. Heterocyclic ketone prostaglandin analogs
IE920039A1 (en) * 1991-02-01 1992-08-12 Squibb & Sons Inc Heterocyclic amido prostaglandin analogs
US5238951A (en) * 1991-02-01 1993-08-24 E. R. Squibb & Sons, Inc. Heterocyclic amido prostaglandin analogs
US5158967A (en) * 1991-06-12 1992-10-27 E. R. Squibb & Sons, Inc. 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease
US5162352A (en) * 1991-08-22 1992-11-10 E. R. Squibb & Sons, Inc. 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs
US5280034A (en) * 1991-08-23 1994-01-18 E. R. Squibb & Sons, Inc. Bis-heterocyclic prostaglandin analogs
CA2081679A1 (en) * 1991-11-27 1993-05-28 Raj N. Misra Gem-dialkyl-7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease
US5399725A (en) * 1993-05-27 1995-03-21 Bristol-Myers Squibb Co. 7-oxabicycloheptane carboxylic acid prostaglandin analog intermediates useful in the preparation of anti-thrombotic and anti-vasospastic compounds and method for preparing same
US5849766A (en) * 1996-05-31 1998-12-15 Eli Lilly And Company Carbamoyl substituted heterocycles
US5849922A (en) * 1996-05-31 1998-12-15 Eli Lilly And Company Preparation of substituted alkenoic acids
US5856584A (en) * 1997-08-06 1999-01-05 The Nutrasweet Company Preparation of 3,3-dimethylbutyraldehyde by oxidation of 3, 3-dimethylbutanol
US5905175A (en) * 1998-05-20 1999-05-18 The Nutrasweet Company Synthesis and purification of 3,3-dimethylbutyraldehyde via oxidation of 1-chloro-3,3-dimethylbutane with dimethyl sulfoxide
CN113912619B (zh) * 2021-11-26 2022-12-06 沈阳药科大学 五味子中提取分离的倍半萜化合物及其方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4456617A (en) * 1983-01-12 1984-06-26 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction
US4663337A (en) * 1986-04-18 1987-05-05 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted amides useful in the treatment of thrombotic disease

Also Published As

Publication number Publication date
CA2006355A1 (en) 1990-06-23
FI97230B (fi) 1996-07-31
PL165147B1 (pl) 1994-11-30
PT92768B (pt) 1995-12-29
DK663189D0 (da) 1989-12-22
CN1031059C (zh) 1996-02-21
NO895170D0 (no) 1989-12-21
NO175258B (no) 1994-06-13
NO895170L (no) 1990-06-25
JPH02221278A (ja) 1990-09-04
FI896249A0 (fi) 1989-12-22
HUT54161A (en) 1991-01-28
IL92837A (en) 1994-06-24
DK663189A (da) 1990-06-24
EP0374952A3 (en) 1991-03-27
HU8906777D0 (en:Method) 1990-03-28
EP0374952A2 (en) 1990-06-27
ZA899868B (en) 1990-09-26
IL92837A0 (en) 1990-09-17
FI97230C (fi) 1996-11-11
PT92768A (pt) 1990-06-29
KR900009639A (ko) 1990-07-05
PL164552B1 (pl) 1994-08-31
PH27413A (en) 1993-06-21
DK172411B1 (da) 1998-05-25
NZ231962A (en) 1992-10-28
CN1043716A (zh) 1990-07-11
AU4729089A (en) 1990-06-28
NO175258C (no) 1994-09-21
DD286359A5 (de) 1991-01-24
AU617569B2 (en) 1991-11-28

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