MX168756B - PROCEDIMIENTO PARA PREPARAR COMPUESTOS DE IMIDAZO (4,5-b) PIRIDINA - Google Patents

PROCEDIMIENTO PARA PREPARAR COMPUESTOS DE IMIDAZO (4,5-b) PIRIDINA

Info

Publication number
MX168756B
MX168756B MX007489A MX748987A MX168756B MX 168756 B MX168756 B MX 168756B MX 007489 A MX007489 A MX 007489A MX 748987 A MX748987 A MX 748987A MX 168756 B MX168756 B MX 168756B
Authority
MX
Mexico
Prior art keywords
group
compound
general formula
procedure
carbon atoms
Prior art date
Application number
MX007489A
Other languages
English (en)
Spanish (es)
Inventor
Kiyokazu Murakami
Akira Hisamitsu
Naoto Matsuishi
Haruki Takeda
Kenichi Iizumi
Original Assignee
Tokyo Tanabe Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tokyo Tanabe Co filed Critical Tokyo Tanabe Co
Publication of MX168756B publication Critical patent/MX168756B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MX007489A 1986-07-25 1987-07-24 PROCEDIMIENTO PARA PREPARAR COMPUESTOS DE IMIDAZO (4,5-b) PIRIDINA MX168756B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP17355186 1986-07-25
JP62133534A JPH0643426B2 (ja) 1986-07-25 1987-05-30 イミダゾ〔４，５−ｂ〕ピリジン誘導体、その製造法及びそれを含有する抗潰瘍剤

Publications (1)

Publication Number Publication Date
MX168756B true MX168756B (es) 1993-06-07

Family

ID=26467860

Family Applications (1)

Application Number Title Priority Date Filing Date
MX007489A MX168756B (es) 1986-07-25 1987-07-24 PROCEDIMIENTO PARA PREPARAR COMPUESTOS DE IMIDAZO (4,5-b) PIRIDINA

Country Status (14)

Country Link
US (1) US4808596A (OSRAM)
EP (1) EP0254588B1 (OSRAM)
JP (1) JPH0643426B2 (OSRAM)
KR (1) KR940002824B1 (OSRAM)
AR (1) AR245718A1 (OSRAM)
AT (1) ATE71626T1 (OSRAM)
AU (1) AU598564B2 (OSRAM)
CA (1) CA1329204C (OSRAM)
DE (1) DE3776018D1 (OSRAM)
ES (1) ES2038184T3 (OSRAM)
GR (1) GR3003777T3 (OSRAM)
HU (1) HU200458B (OSRAM)
MX (1) MX168756B (OSRAM)
ZA (1) ZA875151B (OSRAM)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU195220B (en) * 1983-05-03 1988-04-28 Byk Gulden Lomberg Chem Fqb Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them
DK585485A (da) * 1984-12-18 1986-08-08 Utsuka Pharm Co Ltd Tetrahydroquinolinderivat, imidazopyridinderivat, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat med mindst en saadan forbindelse
KR950001015B1 (ko) * 1986-01-10 1995-02-07 닛뽕 케미화 가부시끼가이샤 술폭시드 유도체의 제조방법
IT1222412B (it) * 1987-07-31 1990-09-05 Chiesi Farma Spa Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono
JP2679745B2 (ja) * 1989-06-29 1997-11-19 明治製菓株式会社 アゾール誘導体及びそれらを有効成分とする抗潰瘍剤
US5200407A (en) * 1989-06-29 1993-04-06 Meiji Seika Kaburhiki Kaisha Azole derivatives and anti-ulcerative composition containing same
ZW1992A1 (en) * 1991-02-25 1993-09-22 Janssen Pharmaceutica Nv 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol
NZ244301A (en) * 1991-09-20 1994-08-26 Merck & Co Inc Preparation of 2-pyridylmethylsulphinylbenzimidazole and pyridoimidazole derivatives from the corresponding sulphenyl compounds
DE69430747T2 (de) * 1993-07-28 2003-03-06 Aventis Pharma Ltd., West Malling Verbindungen als pde iv und tnf inhibitoren
AU6551198A (en) * 1997-05-30 1998-12-30 Dr. Reddy's Research Foundation Novel benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them
AU4387799A (en) * 1998-06-26 2000-01-17 Russinsky Limited Pyridine building blocks as intermediates in the synthesis of pharmaceutically active compounds
US6166213A (en) * 1998-08-11 2000-12-26 Merck & Co., Inc. Omeprazole process and compositions thereof
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6780880B1 (en) 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
DE10140492A1 (de) 2001-08-17 2003-08-14 Gruenenthal Gmbh Hydrate von gegebenenfalls substituierten 2-(2-Pyridinyl)methylthio-1H-benzimidazolen und Verfahren zu ihrer Herstellung
AU2003254282A1 (en) * 2002-08-01 2004-02-23 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
FR2845916B1 (fr) * 2002-10-21 2006-07-07 Negma Gild Composition pharmaceutique associant le tenatoprazole et un antagoniste des recepteurs h2 a l'histamine
FR2845917B1 (fr) * 2002-10-21 2006-07-07 Negma Gild Composition pharmaceutique associant le tenatoprazole et un anti-inflammatoire
FR2845915B1 (fr) 2002-10-21 2006-06-23 Negma Gild Utilisation du tenatoprazole pour le traitement du reflux gastro-oesophagien
FR2848555B1 (fr) 2002-12-16 2006-07-28 Negma Gild Enantiomere(-)du tenatoprazole et son application en therapeutique
US20050220870A1 (en) * 2003-02-20 2005-10-06 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
US7507746B2 (en) * 2003-02-24 2009-03-24 Mitsubishi Pharma Corporation Enantiomer of tenatoprazole and the use thereof in therapy
WO2004080487A1 (ja) * 2003-03-13 2004-09-23 Eisai Co. Ltd. 歯ぎしりの予防剤または治療剤
CA2531566C (en) * 2003-07-18 2013-05-07 Santarus, Inc. Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
MXPA06000529A (es) * 2003-07-18 2006-08-11 Santarus Inc Formulaciones farmaceuticas utiles para inhibir la secrecion de acido y metodos para elaborarlas y utilizarlas.
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
US20050249806A1 (en) * 2004-02-10 2005-11-10 Santarus, Inc. Combination of proton pump inhibitor, buffering agent, and nonsteroidal anti-inflammatory drug
CA2561700A1 (en) * 2004-04-16 2005-12-15 Santarus, Inc. Combination of proton pump inhibitor, buffering agent, and prokinetic agent
TW200606163A (en) * 2004-04-22 2006-02-16 Eisai Co Ltd Imidazopyridine compound
WO2005105799A1 (en) * 2004-04-28 2005-11-10 Altana Pharma Ag Dialkoxy-imidazopyridines derivatives
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
TW200613301A (en) * 2004-06-15 2006-05-01 Altana Pharma Ag Novel amino-halogen-imidazopyridines
FR2871800B1 (fr) * 2004-06-17 2006-08-25 Sidem Pharma Sa Sa Sel de sodium monohydrate du s-tenatoprazole et application en therapeutique
CN100364989C (zh) * 2004-09-30 2008-01-30 江苏豪森药业股份有限公司 拉唑类衍生物及其盐和用途
US20080119510A1 (en) * 2004-12-09 2008-05-22 Altana Pharma Ag Substituted Imidazo [4,5-B] Pyridines As Inhibitors Of Gastric Acid Secretion
US20070015782A1 (en) 2005-04-15 2007-01-18 Eisai Co., Ltd. Benzimidazole compound
US9040564B2 (en) 2005-04-28 2015-05-26 Eisai R&D Management Co., Ltd. Stabilized composition
US7601737B2 (en) 2005-07-26 2009-10-13 Nycomed Gmbh Isotopically substituted proton pump inhibitors
MX2008000901A (es) * 2005-07-26 2008-03-26 Nycomed Gmbh Inhibidores de bomba de protones isotopicamente sustituidos.
CN1982311B (zh) * 2005-12-13 2010-10-13 天津维智精细化工有限公司 2-巯基-5-甲氧基咪唑[4,5-b]并吡啶的合成工艺
CN100376574C (zh) * 2006-06-14 2008-03-26 浙江大学 泰妥拉唑的制备方法
US20100317689A1 (en) * 2006-09-19 2010-12-16 Garst Michael E Prodrugs of proton pump inhibitors including the 1h-imidazo[4,5-b] pyridine moiety
WO2008067037A2 (en) 2006-10-05 2008-06-05 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations
CA2667682A1 (en) 2006-10-27 2008-05-15 The Curators Of The University Of Missouri Compositions comprising acid labile proton pump inhibiting agents, at least one other pharmaceutically active agent and methods of using same
FR2909380B1 (fr) * 2006-12-04 2009-02-20 Sidem Pharma Sa Sa Conglomerats de sels de potassium de tenatoprazole
US8247440B2 (en) 2008-02-20 2012-08-21 Curators Of The University Of Missouri Composition comprising omeprazole, lansoprazole and at least one buffering agent
ES2445711T3 (es) 2009-07-07 2014-03-04 Council Of Scientific & Industrial Research Procedimiento de flujo continuo para la preparación de compuestos de sulfóxido
WO2013108068A1 (en) 2012-01-21 2013-07-25 Jubilant Life Sciences Limited Process for the preparation of 2-pyridinylmethylsulfinyl benzimidazoles, their analogs and optically active enantiomers
EP4598528A1 (en) 2022-10-04 2025-08-13 Arsenil Zabirnyk Inhibition of aortic valve calcification

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234058A (OSRAM) * 1968-10-21 1971-06-03
HU195220B (en) * 1983-05-03 1988-04-28 Byk Gulden Lomberg Chem Fqb Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them
JPS6034956A (ja) * 1983-08-04 1985-02-22 Fujisawa Pharmaceut Co Ltd 新規チアゾリウム化合物およびその製造法
DK585485A (da) * 1984-12-18 1986-08-08 Utsuka Pharm Co Ltd Tetrahydroquinolinderivat, imidazopyridinderivat, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat med mindst en saadan forbindelse
KR950001015B1 (ko) * 1986-01-10 1995-02-07 닛뽕 케미화 가부시끼가이샤 술폭시드 유도체의 제조방법
JPS62207271A (ja) * 1986-03-06 1987-09-11 Yamanouchi Pharmaceut Co Ltd ２−ピリジルメチルチオ基または２−ピリジルメチルスルフイニル基で置換された縮合環化合物
IT1222412B (it) * 1987-07-31 1990-09-05 Chiesi Farma Spa Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
GR3003777T3 (OSRAM) 1993-03-16
AR245718A1 (es) 1994-02-28
AU598564B2 (en) 1990-06-28
KR880001651A (ko) 1988-04-25
JPS63146882A (ja) 1988-06-18
EP0254588B1 (en) 1992-01-15
DE3776018D1 (de) 1992-02-27
ATE71626T1 (de) 1992-02-15
AU7562887A (en) 1988-01-28
EP0254588A1 (en) 1988-01-27
CA1329204C (en) 1994-05-03
US4808596A (en) 1989-02-28
KR940002824B1 (ko) 1994-04-04
HU200458B (en) 1990-06-28
JPH0643426B2 (ja) 1994-06-08
ZA875151B (en) 1988-01-21
HUT46000A (en) 1988-09-28
ES2038184T3 (es) 1993-07-16

Similar Documents

Publication Publication Date Title
MX168756B (es) PROCEDIMIENTO PARA PREPARAR COMPUESTOS DE IMIDAZO (4,5-b) PIRIDINA
ES2089585T3 (es) Derivados de vitamina d sustituidos con metilo en posicion 20.
KR840004106A (ko) 4급 6,11-디하이드로-디벤조-[b,e]-티에핀-11-N-알킬-노르스코핀 에테르의 제조방법
KR870008906A (ko) 마크로라이드 유도체의 제조방법
CO4940436A1 (es) Derivados de 5´-desoxicitidina y proceso de fabricacion de los mismos
ES2037708T3 (es) Un procedimiento para preparar un derivado de bencimidazol.
AR036176A1 (es) Un derivado de fenil-acetamido-tiazol, un procedimiento para su preparacion, una composicion farmaceutica que lo comprende, un producto o kit que los comprende, y un metodo que utiliza dicho derivado
SE8604950D0 (sv) Dementia-improving and therapeutic agents
KR910004633A (ko) 신규한 2-옥소-1옥사-8-아자스피로[4,5]데칸 유도체와 이들을 포함하는 약학적 조성물 및 그 제조방법
KR910000711A (ko) 크로만 유도체
KR860700250A (ko) 신규 아미딘 화합물
NO854677L (no) Fremgangsmaate for fremstilling av 5-alkyl-1-fenyl-2-piperazinoalkylpyrazolin-3-on-forbindelser.
SE7704616L (sv) Sett att framstella nya 11-desoxi-prostaglandin-fÿ2-derivat
YU47010B (sh) Derivati 1,6-naftiridina
ES2051694T3 (es) Derivados de ergolina disustituidos en posiciones 1,2.
KR830007539A (ko) 시스테인 유동체의 분자내 또는 분자간 이황화물의 제조방법
ES536649A0 (es) Procedimiento para la preparacion de derivados de estrano y androstano
KR880013901A (ko) 티에노피리딘 유도체 및 항궤양제
ATE215934T1 (de) Neue histidinderivate, verfahren zu ihrer herstellung und ihre verwendung als mittel gegen freie radikale
DE69815380D1 (de) N,n'-bis (sulfonyl) hydrazine die als antineoplastische mittel nützlich sind
SE7603640L (sv) Sett for framstellning av olosliga, biologiskt aktiva foreningar
MX9304677A (es) Procedimiento para la preparacion de compuestos defenol polihidrico.
ES8201525A1 (es) Un procedimiento para la preparacion de nuevos derivados de 1,1'-bifenil-2-il-alquilamina
MA20552A1 (fr) Alkylacarboxamides de pyridylalkylamines,leurs preparations et leurs utilisations
ES394972A1 (es) Procedimiento para la preparacion de nuevos 3 - alcohil - ariloximetilisoxazoles.