MX166703B - Preparacion farmaceutica para liberacion sostenida - Google Patents

Preparacion farmaceutica para liberacion sostenida

Info

Publication number
MX166703B
MX166703B MX020144A MX2014490A MX166703B MX 166703 B MX166703 B MX 166703B MX 020144 A MX020144 A MX 020144A MX 2014490 A MX2014490 A MX 2014490A MX 166703 B MX166703 B MX 166703B
Authority
MX
Mexico
Prior art keywords
microencapsular
pharmaceutical preparation
sustained release
drug
wall
Prior art date
Application number
MX020144A
Other languages
English (en)
Inventor
Herman J Eichel
Brent D Massmann
Original Assignee
Kinaform Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kinaform Technology Inc filed Critical Kinaform Technology Inc
Publication of MX166703B publication Critical patent/MX166703B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Furan Compounds (AREA)

Abstract

La presente invención se refiere a una preparación farmacéutica de liberación sostenida que se caracteriza porque comprende la mezcla de: a) un medicamento con recubrimiento de pared simple o sin recubrimiento; y b) unidades múltiples de micropartículas del medicamento recubierto que comprende un núcleo de dicho medicamento recubierto con un recubrimiento entérico microencapsular de pared interior que no se disuelve o dispersa rápidamente en el estomago sino que se disuelve o dispersa en los intestinos y un recubrimiento de control microencapsular de pared exterior que no se disuelve o dispersa rápidamente en los intestinos, sino que permite la liberación de dicho medicamento a través del recubrimiento microencapsular mencionado.
MX020144A 1989-04-03 1990-04-02 Preparacion farmaceutica para liberacion sostenida MX166703B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/332,154 US5026559A (en) 1989-04-03 1989-04-03 Sustained-release pharmaceutical preparation

Publications (1)

Publication Number Publication Date
MX166703B true MX166703B (es) 1993-01-28

Family

ID=23296943

Family Applications (1)

Application Number Title Priority Date Filing Date
MX020144A MX166703B (es) 1989-04-03 1990-04-02 Preparacion farmaceutica para liberacion sostenida

Country Status (9)

Country Link
US (1) US5026559A (es)
EP (1) EP0391518B1 (es)
JP (1) JPH02289512A (es)
AR (1) AR244088A1 (es)
AU (1) AU622526B2 (es)
DD (1) DD299946A5 (es)
DE (1) DE69003568T2 (es)
HU (1) HU214576B (es)
MX (1) MX166703B (es)

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Also Published As

Publication number Publication date
HUT74088A (en) 1996-11-28
EP0391518A3 (en) 1991-05-08
AU5079290A (en) 1990-10-04
AR244088A1 (es) 1993-10-29
EP0391518B1 (en) 1993-09-29
DE69003568T2 (de) 1994-02-10
US5026559A (en) 1991-06-25
HU900583D0 (en) 1990-04-28
HU214576B (hu) 1998-04-28
JPH02289512A (ja) 1990-11-29
AU622526B2 (en) 1992-04-09
DD299946A5 (de) 1992-05-14
DE69003568D1 (de) 1993-11-04
EP0391518A2 (en) 1990-10-10

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