ES2073677T3 - Revestimientos de liberacion sostenida y enmascaramiento del sabor para productos farmaceuticos. - Google Patents

Revestimientos de liberacion sostenida y enmascaramiento del sabor para productos farmaceuticos.

Info

Publication number
ES2073677T3
ES2073677T3 ES91304631T ES91304631T ES2073677T3 ES 2073677 T3 ES2073677 T3 ES 2073677T3 ES 91304631 T ES91304631 T ES 91304631T ES 91304631 T ES91304631 T ES 91304631T ES 2073677 T3 ES2073677 T3 ES 2073677T3
Authority
ES
Spain
Prior art keywords
sustained release
pharmaceutical products
release coatings
flavor masking
granules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91304631T
Other languages
English (en)
Inventor
Edward J Roche
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johnson and Johnson Consumer Inc
Original Assignee
McNeil PPC Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McNeil PPC Inc filed Critical McNeil PPC Inc
Application granted granted Critical
Publication of ES2073677T3 publication Critical patent/ES2073677T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

TABLETAS DE MEDICAMENTO MASTICABLES SE ELABORAN A PARTIR DE GRANULOS REVESTIDOS DE UN MEDICAMENTO EN DONDE EL REVESTIMIENTO DE DICHOS GRANULOS INCLUYE UNA MEZCLA DE ACETATO DE CELULOSA Y/O BUTIRATO DE ACETATO DE CELULOSA Y CELULOSA DE HIDROXIPROPILO Y UN PROCESO PARA ELABORAR ESTAS TABLETAS Y UN METODO PARA PROPORCIONAR UNA LIBERACION CONTINUA DE MEDICAMENTOS UTILIZANDO ESTOS GRANULOS REVESTIDOS EN UNA TABLETA.
ES91304631T 1990-05-23 1991-05-22 Revestimientos de liberacion sostenida y enmascaramiento del sabor para productos farmaceuticos. Expired - Lifetime ES2073677T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/528,003 US5075114A (en) 1990-05-23 1990-05-23 Taste masking and sustained release coatings for pharmaceuticals
IN325CA1991 IN172428B (es) 1990-05-23 1991-04-29

Publications (1)

Publication Number Publication Date
ES2073677T3 true ES2073677T3 (es) 1995-08-16

Family

ID=26324259

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91304631T Expired - Lifetime ES2073677T3 (es) 1990-05-23 1991-05-22 Revestimientos de liberacion sostenida y enmascaramiento del sabor para productos farmaceuticos.

Country Status (11)

Country Link
US (1) US5075114A (es)
EP (1) EP0459695B1 (es)
JP (1) JP3157190B2 (es)
AU (1) AU639334B2 (es)
CA (1) CA2042289C (es)
ES (1) ES2073677T3 (es)
GR (1) GR1002092B (es)
IE (1) IE67062B1 (es)
IN (1) IN172428B (es)
NZ (1) NZ238131A (es)
PT (1) PT97739B (es)

Families Citing this family (148)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5460825A (en) * 1990-05-23 1995-10-24 Mcneil-Ppc, Inc. Taste mask coatings for preparing chewable pharmaceutical tablets
DK0537139T3 (da) * 1990-07-02 1994-08-22 Boehringer Mannheim Gmbh Fremgangsmåde til fremstilling af formede, pressede dosisenheder med forsinket frigørelse og dertil svarende dosisenhed
CA2104684A1 (en) * 1991-03-04 1992-09-05 Mahdi B. Fawzi Salts/ion pairs of non-steroidal anti-inflammatory drugs in various dosage forms
EP0583399A4 (en) * 1991-04-30 1997-04-23 Fmc Corp Taste-masked medicaments and their preparation
CA2079934C (en) * 1991-10-15 2002-09-03 Edward J. Roche Taste mask coatings for preparing chewable pharmaceutical tablets
GR1002332B (el) * 1992-05-21 1996-05-16 Mcneil-Ppc Inc. Νεες φαρμακευτικες συνθεσεις που περιεχουν σιμεθεικονη.
EP0572731A1 (en) * 1992-06-01 1993-12-08 The Procter & Gamble Company Chewable preparation containing a decongestant
US5837277A (en) * 1992-06-04 1998-11-17 Smithkline Beecham Corporation Palatable pharmaceutical compositions
ATE217789T1 (de) * 1992-06-04 2002-06-15 Smithkline Beecham Corp Angenehm schmeckende pharmazeutische zusammensetzungen
GB9221414D0 (en) * 1992-10-13 1992-11-25 Glaxo Group Ltd Pharmaceutical compositions
MX9306393A (es) * 1992-10-16 1994-04-29 Glaxo Group Ltd Composiciones de ranitidina substancialmente libres de sabor amargo, proceso para su preparacion y composiciones farmaceuticas que las contienen.
CA2150119C (en) * 1992-11-30 2005-03-15 Robert C. Cuca Tastemasked pharmaceutical materials
CA2110313C (en) * 1992-12-01 2004-10-26 Edward John Roche Pharmaceutical compositions containing a guanidinothiazole compound and antacids
US6313202B1 (en) * 1993-05-28 2001-11-06 Eastman Chemical Company Cellulose ester blends
CA2166891C (en) * 1993-07-09 2001-07-03 Sang K. Wong Method for making freeze dried drug dosage forms
CA2128820A1 (en) * 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
CA2128821A1 (en) * 1993-07-27 1995-01-28 Dilip J. Gole Freeze-dried pharmaceutical dosage form and process for separation thereof
US5622980A (en) * 1993-08-17 1997-04-22 Applied Analytical Industries, Inc. Oral compositions of H2-antagonists
HUT72408A (en) * 1993-09-10 1996-04-29 Egyt Gyogyszervegyeszeti Gyar Process for producing tablets containing acetyl-salicylic acid
US5536505A (en) * 1993-12-15 1996-07-16 Eastman Chemical Company Controlled release matrix system using cellulose acetate/poly-2-ethyl-2-oxazoline blends
US5470865A (en) * 1994-08-30 1995-11-28 Eli Lilly And Company Pharmaceutical composition
US5529783A (en) 1994-12-19 1996-06-25 Mcneil-Ppc, Inc. Rotor granulation and coating of acetaminophen, pseudoephedrine, chlorpheniramine, and, optionally dextromethorphan
AUPN605795A0 (en) * 1995-10-19 1995-11-09 F.H. Faulding & Co. Limited Analgesic pharmaceutical composition
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
AU4078897A (en) * 1996-08-23 1998-03-06 Algos Pharmaceutical Corporation Anticonvulsant containing composition for treating neuropathic pain
IL129242A0 (en) * 1996-10-01 2000-02-17 Cima Labs Inc Taste-masked microcapsule compositions and methods of manufacture
JP3001440B2 (ja) * 1996-11-25 2000-01-24 日本電気通信システム株式会社 仮想lan方式
US5904937A (en) * 1997-10-03 1999-05-18 Fmc Corporation Taste masked pharmaceutical compositions
UA65607C2 (uk) * 1998-03-04 2004-04-15 Орто-Макнейл Фармацевтикал, Інк. Фармацевтична композиція (варіанти) та спосіб її приготування
US6270790B1 (en) 1998-08-18 2001-08-07 Mxneil-Ppc, Inc. Soft, convex shaped chewable tablets having reduced friability
CZ20012201A3 (cs) * 1998-12-18 2001-09-12 Abbott Laboratories Přípravek s řízeným uvolňováním obsahující divalproex sodný
US6270807B1 (en) 1999-03-02 2001-08-07 L. Perrigo Company Taste-masked pharmaceutical composition
US6211246B1 (en) * 1999-06-10 2001-04-03 Mcneil-Ppc, Inc. Rapidly absorbed liquid compositions
US6428809B1 (en) * 1999-08-18 2002-08-06 Microdose Technologies, Inc. Metering and packaging of controlled release medication
US6451345B1 (en) 2000-01-20 2002-09-17 Eurand Pharmaceuticals Ltd. Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration
US20020119196A1 (en) * 2000-12-21 2002-08-29 Narendra Parikh Texture masked particles containing an active ingredient
US20020122823A1 (en) * 2000-12-29 2002-09-05 Bunick Frank J. Soft tablet containing dextrose monohydrate
US20030096791A1 (en) * 2001-05-31 2003-05-22 Cima Labs Inc. Taste masking of highly water-soluble drugs
GB0113839D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
US7914811B2 (en) 2001-06-29 2011-03-29 Mcneil-Ppc, Inc. Brittle-coating, soft core dosage form
US20030060422A1 (en) 2001-08-31 2003-03-27 Balaji Venkataraman Tannate compositions and methods of treatment
US7217381B2 (en) * 2001-09-28 2007-05-15 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US7101573B2 (en) * 2001-09-28 2006-09-05 Mcneil-Pcc, Inc. Simethicone solid oral dosage form
US6837696B2 (en) * 2001-09-28 2005-01-04 Mcneil-Ppc, Inc. Apparatus for manufacturing dosage forms
US7323192B2 (en) 2001-09-28 2008-01-29 Mcneil-Ppc, Inc. Immediate release tablet
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
BR0212950A (pt) 2001-09-28 2004-10-26 Mcneil Ppc Inc Formas de dosagens compósitas tendo uma porção inserida
US6982094B2 (en) 2001-09-28 2006-01-03 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US6767200B2 (en) * 2001-09-28 2004-07-27 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US6742646B2 (en) * 2001-09-28 2004-06-01 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US6723348B2 (en) * 2001-11-16 2004-04-20 Ethypharm Orodispersible tablets containing fexofenadine
US6753009B2 (en) 2002-03-13 2004-06-22 Mcneil-Ppc, Inc. Soft tablet containing high molecular weight polyethylene oxide
US7169450B2 (en) * 2002-05-15 2007-01-30 Mcneil-Ppc, Inc. Enrobed core
US20040081695A1 (en) * 2002-09-28 2004-04-29 Sowden Harry S Dosage forms having an inner core and an outer shell
US7807197B2 (en) 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
US20040109889A1 (en) * 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US20040258752A1 (en) * 2003-01-31 2004-12-23 Paruthi Manoj Kumar Taste masking pharmaceutical composition and process for its preparation
US20040265373A1 (en) * 2003-06-27 2004-12-30 David Wynn Soft tablet containing high molecular weight cellulosics
US20040265372A1 (en) * 2003-06-27 2004-12-30 David Wynn Soft tablet containing high molecular weight cellulosics
US7632521B2 (en) 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
JP2007501810A (ja) * 2003-08-11 2007-02-01 メルク フロスト カナダ リミテツド 一段階被覆法を用いて作製された着香味遮蔽製薬製剤
US20050069590A1 (en) * 2003-09-30 2005-03-31 Buehler Gail K. Stable suspensions for medicinal dosages
US20050074514A1 (en) * 2003-10-02 2005-04-07 Anderson Oliver B. Zero cycle molding systems, methods and apparatuses for manufacturing dosage forms
US20050175689A1 (en) * 2003-10-27 2005-08-11 Yamanouchi Pharmaceutical Co., Ltd. Coated fine particles containing drug for intrabuccally fast disintegrating tablet
JPWO2005039542A1 (ja) * 2003-10-27 2007-02-15 アステラス製薬株式会社 口腔内崩壊錠用の薬物含有被覆微粒子
US7201920B2 (en) 2003-11-26 2007-04-10 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of opioid containing dosage forms
KR20070010132A (ko) * 2004-03-25 2007-01-22 아스텔라스세이야쿠 가부시키가이샤 솔리페나신 또는 그의 염의 고형 제제용 조성물
US8545881B2 (en) * 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
NZ728442A (en) 2004-10-21 2018-05-25 Adare Pharmaceuticals Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US20060088587A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060088593A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060088586A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US8383159B2 (en) * 2004-10-27 2013-02-26 Mcneil-Ppc, Inc. Dosage forms having a microreliefed surface and methods and apparatus for their production
US20070281022A1 (en) * 2004-10-27 2007-12-06 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20070190133A1 (en) * 2004-10-27 2007-08-16 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060087051A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
CA2591761A1 (en) * 2004-12-27 2006-07-06 Astellas Pharma Inc. Stable particulate pharmaceutical composition of solifenacin or salt thereof
US8673352B2 (en) 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
US7815939B2 (en) * 2005-07-20 2010-10-19 Astellas Pharma Inc. Coated fine particles containing drug for intrabuccally fast disintegrating dosage forms
EP1911444A1 (en) * 2005-07-20 2008-04-16 Astellas Pharma Inc. Drug-containing coated fine particle for intrabuccally disintegrating preparation and method of producing the same
US8778395B2 (en) 2005-08-11 2014-07-15 Andrx Labs, Llc Diltiazem controlled release formulation and method of manufacture
US20070077300A1 (en) * 2005-09-30 2007-04-05 Wynn David W Oral compositions containing a salivation inducing agent
JP2009531460A (ja) * 2006-03-28 2009-09-03 マクニール−ピーピーシー・インコーポレイテッド 不均一な投薬形態コーティング
US20070286903A1 (en) * 2006-06-13 2007-12-13 Becicka Brian T Composition and method for taste masking
US20080031927A1 (en) * 2006-07-11 2008-02-07 Catani Steven J Solid oral dosage vitamin and mineral compositions
MX2009004203A (es) 2006-10-20 2009-07-02 Mcneil Ppc Inc Combinaciones de paracetamol/ibuprofeno y metodo para su uso.
US20080194307A1 (en) * 2007-02-13 2008-08-14 Jeff Sanger Sports-based game of chance
GB2447898B (en) * 2007-03-24 2011-08-17 Reckitt Benckiser Healthcare A tablet having improved stability with at least two actives
EP2162153B1 (en) * 2007-06-06 2016-03-30 Novus International Inc. Dietary supplements for promotion of growth, repair, and maintenance of bone and joints
US20090004248A1 (en) * 2007-06-29 2009-01-01 Frank Bunick Dual portion dosage lozenge form
KR20100087287A (ko) * 2007-09-17 2010-08-04 맥네일-피피씨, 인코포레이티드 폴리비닐 알코올과 폴리에틸렌 글리콜의 공중합체 및 검을 포함하는 침지 코팅 조성물
US8439033B2 (en) 2007-10-09 2013-05-14 Microdose Therapeutx, Inc. Inhalation device
AU2008318851B2 (en) 2007-10-31 2014-04-17 Mcneil-Ppc, Inc. Orally disintegrated dosage form
CA2709709A1 (en) 2007-12-21 2009-07-09 Mcneil-Ppc, Inc. Manufacture of tablet
KR20100129740A (ko) * 2008-02-19 2010-12-09 맥네일-피피씨, 인코포레이티드 아밀로스 함량이 높은 전분을 포함하는 침지 코팅 조성물
AU2009223061B2 (en) 2008-03-11 2014-10-09 Depomed Inc. Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic
US8372432B2 (en) 2008-03-11 2013-02-12 Depomed, Inc. Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic
CN102119027A (zh) * 2008-06-26 2011-07-06 麦克内尔-Ppc股份有限公司 含有药物活性剂的包衣颗粒
JP2011527607A (ja) 2008-07-08 2011-11-04 ハイパーブランチ メディカル テクノロジー, インコーポレイテッド 多成分処方のための独立式医療用アプリケータおよびその使用方法
AU2009279521A1 (en) * 2008-08-08 2010-02-11 Mcneil-Ppc, Inc. Use of sucralose as a granulating agent
CA2741701A1 (en) * 2008-10-31 2010-05-06 Mcneil-Ppc, Inc. Osmotic tablet with a compressed outer coating
US20100247586A1 (en) * 2009-03-27 2010-09-30 Andreas Hugerth Multi-Portion Intra-Oral Dosage Form With Organoleptic Properties
JP2012530781A (ja) * 2009-06-22 2012-12-06 ワイス・エルエルシー イブプロフェンナトリウムタブレット、およびイブプロフェンナトリウムを含有する医薬組成物の製造方法
RU2012102772A (ru) 2009-06-29 2013-08-10 МакНЕЙЛ-ППС, ИНК. Фармацевтическая таблетка, содержащая заполненную жидкостью капсулу
US8313768B2 (en) 2009-09-24 2012-11-20 Mcneil-Ppc, Inc. Manufacture of tablet having immediate release region and sustained release region
US20110318411A1 (en) 2010-06-24 2011-12-29 Luber Joseph R Multi-layered orally disintegrating tablet and the manufacture thereof
US20110070301A1 (en) 2009-09-24 2011-03-24 Luber Joseph R Orally transformable tablets
WO2011041470A2 (en) 2009-09-30 2011-04-07 Mallinckrodt Inc. Sustained-release opiate and opiate derivative compositions
ES2569925T3 (es) * 2009-09-30 2016-05-13 Acura Pharmaceuticals, Inc. Métodos y composiciones de disuasión del abuso
MX2012006240A (es) 2009-12-02 2012-10-03 Aptalis Pharma Ltd Microcapsulas de fexofenadina y composiciones que contienen las mismas.
WO2011087765A2 (en) 2009-12-22 2011-07-21 Mallinckrodt Inc. Methods of producing stabilized solid pharmaceutical compositions containing morphinans
US8597681B2 (en) 2009-12-22 2013-12-03 Mallinckrodt Llc Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
US9198861B2 (en) 2009-12-22 2015-12-01 Mallinckrodt Llc Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
US20110150989A1 (en) 2009-12-22 2011-06-23 Mallinkckrodt Inc. Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans
EP3431128A1 (en) 2010-01-05 2019-01-23 MicroDose Therapeutx, Inc. Inhalation device and method
WO2012039789A1 (en) 2010-09-22 2012-03-29 Mcneil-Ppc, Inc. Manufacture of variable density dosage forms utilizing radiofrequency energy
CN103124552A (zh) 2010-09-22 2013-05-29 麦克内尔-Ppc股份有限公司 由施以能量的粉末共混物制造片剂
US8741885B1 (en) 2011-05-17 2014-06-03 Mallinckrodt Llc Gastric retentive extended release pharmaceutical compositions
US8858963B1 (en) 2011-05-17 2014-10-14 Mallinckrodt Llc Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia
US8658631B1 (en) 2011-05-17 2014-02-25 Mallinckrodt Llc Combination composition comprising oxycodone and acetaminophen for rapid onset and extended duration of analgesia
US9233491B2 (en) 2012-05-01 2016-01-12 Johnson & Johnson Consumer Inc. Machine for production of solid dosage forms
US20130295174A1 (en) 2012-05-01 2013-11-07 Mcneil-Ppc, Inc. Tablet comprising a first and second region
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet
US9445971B2 (en) 2012-05-01 2016-09-20 Johnson & Johnson Consumer Inc. Method of manufacturing solid dosage form
RU2673818C2 (ru) 2012-11-30 2018-11-30 Экьюра Фармасьютикалз, Инк. Саморегулируемое высвобождение фармацевтического ингредиента
EP3091966B1 (en) 2014-01-10 2019-07-31 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
JP6510628B2 (ja) 2014-03-26 2019-05-15 サン・ファーマ・アドバンスト・リサーチ・カンパニー・リミテッド 乱用防止即時放出性被覆リザーバ固体剤形
US20150328162A1 (en) * 2014-05-15 2015-11-19 Mario Medri Pharmaceutical preparations
EP2952103B1 (de) * 2014-06-05 2019-05-08 Symrise AG Stoffgemische
MA40859A (fr) 2014-10-29 2017-09-05 Johnson & Johnson Consumer Inc Particules de cadotril
WO2017040607A1 (en) 2015-08-31 2017-03-09 Acura Pharmaceuticals, Inc. Methods and compositions for self-regulated release of active pharmaceutical ingredient
JP6812104B2 (ja) * 2015-12-28 2021-01-13 エスエス製薬株式会社 経口固形組成物
US20180147153A1 (en) 2016-11-28 2018-05-31 Johnson & Johnson Consumer Inc. Process for making a coated dosage form
US10493026B2 (en) 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
BR112019023664A8 (pt) 2017-05-22 2022-07-26 Currahee Holding Company Inc Forma de dosagem em pastilha
WO2019090061A1 (en) 2017-11-02 2019-05-09 Bioventures, Llc Use of amino acid supplementation for improved muscle protein synthesis
US20190166878A1 (en) 2017-12-06 2019-06-06 Nutriquest, Llc Feed additive compositions
JP2021524741A (ja) 2018-05-18 2021-09-16 アナベックス ライフ サイエンス コーポレイション レスポンダ選択および治療の最適化されたsigma−1アゴニスト方法
JP2022504333A (ja) * 2018-10-05 2022-01-13 アイエスピー インヴェストメンツ エルエルシー 水溶性セルロースエーテルを含有する平滑な高固形分フィルムコーティング組成物、その調製方法およびその使用方法
SG11202107999PA (en) * 2019-02-20 2021-09-29 Suntory Holdings Ltd Protein-containing oral composition and method for improving flavor of protein-containing oral composition
EP4209292A1 (fr) * 2021-02-22 2023-07-12 Comadur S.A. Outil de coupe avec des orifices de lubrification de formes complexes
CA3240771A1 (en) 2021-12-17 2023-06-22 Kim Friesen Methods of improving the nutritional status of immune stressed animals

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK150008C (da) * 1981-11-20 1987-05-25 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat
US4643892A (en) * 1983-07-20 1987-02-17 Warner-Lambert Company Magnesium trisilicate suitable for preparation of medicament adsorbates of analgesics
US4894233A (en) * 1984-10-05 1990-01-16 Sharma Shri C Novel drug delivery system for decongestants
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
GB8618811D0 (en) * 1986-08-01 1986-09-10 Approved Prescription Services Sustained release ibuprofen formulation
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
US4835187A (en) * 1987-06-15 1989-05-30 American Home Products Corporation Spray dried ibuprofen
US4915949A (en) * 1987-07-13 1990-04-10 Alza Corporation Dispenser with movable matrix comprising a plurality of tiny pills
US4915953A (en) * 1987-09-03 1990-04-10 Alza Corporation Dosage form for delivering acetaminophen or phenylpropanolamine
US4837031A (en) * 1987-09-17 1989-06-06 Mallinckrodt, Inc. Compositions containing ibuprofen
NZ226822A (en) * 1987-11-16 1990-03-27 Mcneil Consumer Prod Chewable medicament tablet containing means for taste masking
US4851226A (en) * 1987-11-16 1989-07-25 Mcneil Consumer Products Company Chewable medicament tablet containing means for taste masking
US4835188A (en) * 1987-12-08 1989-05-30 American Home Products Corporation Spray dried ibuprofen

Also Published As

Publication number Publication date
PT97739B (pt) 1998-10-30
IE67062B1 (en) 1996-02-21
PT97739A (pt) 1992-03-31
JPH06316536A (ja) 1994-11-15
GR910100204A (el) 1992-07-30
CA2042289A1 (en) 1991-11-24
EP0459695A1 (en) 1991-12-04
EP0459695B1 (en) 1995-03-15
GR1002092B (en) 1995-12-28
NZ238131A (en) 1992-09-25
AU639334B2 (en) 1993-07-22
US5075114A (en) 1991-12-24
IE911752A1 (en) 1991-12-04
CA2042289C (en) 1998-12-08
JP3157190B2 (ja) 2001-04-16
AU7723491A (en) 1991-11-28
IN172428B (es) 1993-07-24

Similar Documents

Publication Publication Date Title
ES2073677T3 (es) Revestimientos de liberacion sostenida y enmascaramiento del sabor para productos farmaceuticos.
ES2081349T3 (es) Rotogranulaciones y recubrimientos para enmascarar el sabor para la preparacion de comprimidos farmaceuticos de mascar.
ES2089403T3 (es) Recubrimiento para ocultar el sabor para la preparacion de tabletas farmaceuticas masticables.
KR870003778A (ko) 신규 약제의 제조방법
AR028299A1 (es) Una composicion farmaceutica que comprende nateglinida, un proceso para su preparacion y el uso de dicha composicion para la preparacion de un medicamento para el tratamiento de desordenes metabolicos, especialmente diabetes, o de una enfermedad o condicion asociada con diabetes.
DE69318415D1 (de) Arzneitablette, die befähigt ist, einen oder mehrere wirkstoffe mit unterschiedlichen abgaberaten freizusetzen
GR3001238T3 (en) Process for the preparation of an administration and dosage for drugs, reagents or other active substances
ATE164843T1 (de) Naphthalinderivate, ihre herstellungsverfahren und zwischenprodukte dafür, und diese enthaltende pharmazeutische zusammensetzungen
DE69812936D1 (de) Arzneimittel in form parenenteral verabreichbarer lipidmikropartikel
CA2063141A1 (en) Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
ZA795530B (en) Pharmaceutical tablet for oral administration and process for its manufacture
BE750960A (fr) Derives de la quinazolinone, leur preparation et medicaments contenant ces derives
GR1000261B (el) Μασητικο δισκιο φαρμακου το οποιο περιεχει μεσον για την επικαλυψη της γευσεως.
FI905684A0 (fi) Farmaceutisk doseringsform foer utdelning av medicin aot fiskar.
ES2088550T3 (es) Recubrimientos que ocultan el sabor para preparar comprimidos farmaceuticos masticables.
ATE187640T1 (de) Arzneimittel in tablettenform mit verzögerter wirkstoffabgabe auf basis von hochmolekularen polysaccharidgranulaten
GB9814215D0 (en) Anti-inflammatory pharmaceutical formulations
ES2073688T3 (es) Rotogranulaciones y revestimiento de enmascaramiento del sabor para la preparacion de tabletas farmaceuticas masticables.
ES2010466A6 (es) Formas de administracion solidas, de rapida desintegracion.
DK0421541T3 (da) Tabletstruktur, som kan deles
BE809009A (fr) Procede d'enrobage de comprimes a usage pharmaceutique et produits enrobes nouveaux
ES2062804T3 (es) Medicamento recubierto con gelatina y procedimiento para fabricar el mismo.
ES2118451T3 (es) Preparado medicamentoso oral que contiene diclofenaco sodico y un acido organico.
CA937866A (en) Process for the manufacture of a drug dosage form permitting controlled release of active ingredient
GT199100040A (es) Revestimientos enmascaradores de sabor y de liberacion sostenida para productos farmaceuticos.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 459695

Country of ref document: ES