DE69812936D1 - Arzneimittel in form parenenteral verabreichbarer lipidmikropartikel - Google Patents

Arzneimittel in form parenenteral verabreichbarer lipidmikropartikel

Info

Publication number
DE69812936D1
DE69812936D1 DE69812936T DE69812936T DE69812936D1 DE 69812936 D1 DE69812936 D1 DE 69812936D1 DE 69812936 T DE69812936 T DE 69812936T DE 69812936 T DE69812936 T DE 69812936T DE 69812936 D1 DE69812936 D1 DE 69812936D1
Authority
DE
Germany
Prior art keywords
parenenteral
administrative
medicinal product
lipid microparticle
microparticle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69812936T
Other languages
English (en)
Other versions
DE69812936T2 (de
Inventor
Maria Rosa Gasco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE69812936D1 publication Critical patent/DE69812936D1/de
Application granted granted Critical
Publication of DE69812936T2 publication Critical patent/DE69812936T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
DE69812936T 1997-06-12 1998-05-27 Arzneimittel in form parenenteral verabreichbarer lipidmikropartikel Expired - Lifetime DE69812936T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97MI001385A IT1292142B1 (it) 1997-06-12 1997-06-12 Composizione farmaceutica in forma di microparticelle lipidiche solide atte alla somministrazione parenterale
PCT/EP1998/003110 WO1998056362A1 (en) 1997-06-12 1998-05-27 Pharmaceutical composition in form of solid lipidic microparticles suitable to parenteral administration

Publications (2)

Publication Number Publication Date
DE69812936D1 true DE69812936D1 (de) 2003-05-08
DE69812936T2 DE69812936T2 (de) 2004-01-29

Family

ID=11377349

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69812936T Expired - Lifetime DE69812936T2 (de) 1997-06-12 1998-05-27 Arzneimittel in form parenenteral verabreichbarer lipidmikropartikel

Country Status (8)

Country Link
US (1) US6238694B1 (de)
EP (1) EP0988031B1 (de)
AT (1) ATE235897T1 (de)
AU (1) AU7915898A (de)
CA (1) CA2294172C (de)
DE (1) DE69812936T2 (de)
IT (1) IT1292142B1 (de)
WO (1) WO1998056362A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1296914B1 (it) 1997-12-01 1999-08-03 Maria Rosa Gasco Composizione farmaceutica comprendente microparticelle atte al passaggio transmucosale ed al superamento della barriera
IT1303787B1 (it) * 1998-11-25 2001-02-23 Maria Rosa Gasco "nanosfere lipidiche solide atte ad una rapida internalizzazione nellecellule"
JP2003520210A (ja) * 2000-01-05 2003-07-02 イマレックス セラピューティクス， インコーポレイテッド 低い水溶性を有する薬物の送達のための薬学的処方物
US7153525B1 (en) 2000-03-22 2006-12-26 The University Of Kentucky Research Foundation Microemulsions as precursors to solid nanoparticles
US6869617B2 (en) * 2000-12-22 2005-03-22 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US7193084B2 (en) * 2000-12-22 2007-03-20 Baxter International Inc. Polymorphic form of itraconazole
US20050048126A1 (en) * 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
US20030096013A1 (en) * 2000-12-22 2003-05-22 Jane Werling Preparation of submicron sized particles with polymorph control
US9700866B2 (en) * 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US6884436B2 (en) * 2000-12-22 2005-04-26 Baxter International Inc. Method for preparing submicron particle suspensions
US20040256749A1 (en) * 2000-12-22 2004-12-23 Mahesh Chaubal Process for production of essentially solvent-free small particles
US7033348B2 (en) * 2001-04-10 2006-04-25 The Research Foundation Of The City University Of New York Gelatin based on Power-gel™ as solders for Cr4+laser tissue welding and sealing of lung air leak and fistulas in organs
BR0212833A (pt) * 2001-09-26 2004-10-13 Baxter Int Preparação de nanopartìculas de tamanho submìcron através de dispersão e de remoção de solvente ou de fase lìquida
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
US7112340B2 (en) * 2001-10-19 2006-09-26 Baxter International Inc. Compositions of and method for preparing stable particles in a frozen aqueous matrix
EP1480661B1 (de) 2002-02-28 2011-04-13 Heitland & Petre International GmbH Mikro-/nanopartikel aus lipidhaltigen marinen organismen für pharmazie und kosmetik
ES2411656T3 (es) * 2002-03-13 2013-07-08 Thomas SKÖLD Sistemas de administración a base de agua
ITMI20022323A1 (it) * 2002-10-31 2004-05-01 Maria Rosa Gasco Composizioni farmaceutiche atte al trattamento di malattie oftalmiche.
EP1711163A2 (de) * 2004-02-05 2006-10-18 Baxter International Inc. Unter verwendung von selbststabilisierenden mitteln hergestellte dispersionen
AU2006259594A1 (en) * 2005-06-14 2006-12-28 Baxter Healthcare S.A. Pharmaceutical formulations for minimizing drug-drug interactions
US20060280787A1 (en) * 2005-06-14 2006-12-14 Baxter International Inc. Pharmaceutical formulation of the tubulin inhibitor indibulin for oral administration with improved pharmacokinetic properties, and process for the manufacture thereof
EP1954245A2 (de) * 2005-11-15 2008-08-13 Baxter International Inc. Zusammensetzungen aus lipoxygenase-hemmern
US20070154403A1 (en) * 2006-01-05 2007-07-05 Thomas Skold Oral, Pulmonary and Transmucosal Delivery Composition
US20090152176A1 (en) * 2006-12-23 2009-06-18 Baxter International Inc. Magnetic separation of fine particles from compositions
US20080293814A1 (en) * 2007-05-22 2008-11-27 Deepak Tiwari Concentrate esmolol
US8722736B2 (en) * 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
US8426467B2 (en) * 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
ITTO20070411A1 (it) * 2007-06-08 2008-12-09 Univ Degli Studi Torino Metodo per la preparazione di micro e nanoparticelle lipidiche solide
US20090061009A1 (en) * 2007-08-29 2009-03-05 Joseph Schwarz Composition and Method of Treatment of Bacterial Infections
DE102008035442A1 (de) 2008-07-26 2010-01-28 Ernst-Moritz-Arndt-Universität Greifswald Zubereitungen aus Artemisia Annua, ihre Umwandlung in Mikro- und Nanopartikel und ihre Verwendung
WO2013105026A1 (en) * 2012-01-09 2013-07-18 Department Of Biotechnology (Dbt) A process for preparing solid lipid sustained release nanoparticles for delivery of vitamins
DE102013224627A1 (de) * 2013-11-29 2015-06-03 Andreas Lauterbach Pharmazeutische Formulierung mit Lipidmikropartikeln und Herstellungsverfahren
CA2950741C (en) * 2014-05-30 2023-03-28 Oms Investments, Inc. Nano-sized water-based dispersion compositions and methods of making thereof
CA2974196C (en) 2015-01-20 2023-12-12 TetraDerm Group LLC Versatile topical drug delivery vehicle and multifactorial tissue moisturizer that provides mucosal and skin barrier restoration

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985354A (en) * 1995-06-07 1999-11-16 Brown University Research Foundation Preparation of multiwall polymeric microcapsules from hydrophilic polymers
IT1240317B (it) * 1990-02-22 1993-12-07 Maria Rosa Gasco Microsfere lipidiche solide a stretto intervallo dimensionale e relativo procedimento di preparazione
US5145684A (en) * 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
US5250236A (en) * 1991-08-05 1993-10-05 Gasco Maria R Method for producing solid lipid microspheres having a narrow size distribution
CA2091152C (en) * 1993-03-05 2005-05-03 Kirsten Westesen Solid lipid particles, particles of bioactive agents and methods for the manfuacture and use thereof
US5744155A (en) * 1993-08-13 1998-04-28 Friedman; Doron Bioadhesive emulsion preparations for enhanced drug delivery

Also Published As

Publication number Publication date
CA2294172A1 (en) 1998-12-17
ITMI971385A0 (de) 1997-06-12
CA2294172C (en) 2007-01-09
AU7915898A (en) 1998-12-30
EP0988031A1 (de) 2000-03-29
US6238694B1 (en) 2001-05-29
ATE235897T1 (de) 2003-04-15
IT1292142B1 (it) 1999-01-25
ITMI971385A1 (it) 1998-12-12
DE69812936T2 (de) 2004-01-29
WO1998056362A1 (en) 1998-12-17
EP0988031B1 (de) 2003-04-02

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