DE69812936T2 - Arzneimittel in form parenenteral verabreichbarer lipidmikropartikel - Google Patents

Arzneimittel in form parenenteral verabreichbarer lipidmikropartikel Download PDF

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Publication number
DE69812936T2
DE69812936T2 DE69812936T DE69812936T DE69812936T2 DE 69812936 T2 DE69812936 T2 DE 69812936T2 DE 69812936 T DE69812936 T DE 69812936T DE 69812936 T DE69812936 T DE 69812936T DE 69812936 T2 DE69812936 T2 DE 69812936T2
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DE
Germany
Prior art keywords
parenenteral
administrative
medicinal product
lipid microparticle
microparticle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69812936T
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English (en)
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DE69812936D1 (de
Inventor
Maria Rosa Gasco
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Individual
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Individual
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Filing date
Publication date
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Publication of DE69812936D1 publication Critical patent/DE69812936D1/de
Application granted granted Critical
Publication of DE69812936T2 publication Critical patent/DE69812936T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
DE69812936T 1997-06-12 1998-05-27 Arzneimittel in form parenenteral verabreichbarer lipidmikropartikel Expired - Lifetime DE69812936T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97MI001385A IT1292142B1 (it) 1997-06-12 1997-06-12 Composizione farmaceutica in forma di microparticelle lipidiche solide atte alla somministrazione parenterale
PCT/EP1998/003110 WO1998056362A1 (en) 1997-06-12 1998-05-27 Pharmaceutical composition in form of solid lipidic microparticles suitable to parenteral administration

Publications (2)

Publication Number Publication Date
DE69812936D1 DE69812936D1 (de) 2003-05-08
DE69812936T2 true DE69812936T2 (de) 2004-01-29

Family

ID=11377349

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69812936T Expired - Lifetime DE69812936T2 (de) 1997-06-12 1998-05-27 Arzneimittel in form parenenteral verabreichbarer lipidmikropartikel

Country Status (8)

Country Link
US (1) US6238694B1 (de)
EP (1) EP0988031B1 (de)
AT (1) ATE235897T1 (de)
AU (1) AU7915898A (de)
CA (1) CA2294172C (de)
DE (1) DE69812936T2 (de)
IT (1) IT1292142B1 (de)
WO (1) WO1998056362A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102013224627A1 (de) * 2013-11-29 2015-06-03 Andreas Lauterbach Pharmazeutische Formulierung mit Lipidmikropartikeln und Herstellungsverfahren

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1296914B1 (it) * 1997-12-01 1999-08-03 Maria Rosa Gasco Composizione farmaceutica comprendente microparticelle atte al passaggio transmucosale ed al superamento della barriera
IT1303787B1 (it) * 1998-11-25 2001-02-23 Maria Rosa Gasco "nanosfere lipidiche solide atte ad una rapida internalizzazione nellecellule"
WO2001049268A1 (en) * 2000-01-05 2001-07-12 Imarx Therapeutics, Inc. Pharmaceutical formulations for the delivery of drugs having low aqueous solubility
US7153525B1 (en) 2000-03-22 2006-12-26 The University Of Kentucky Research Foundation Microemulsions as precursors to solid nanoparticles
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US20030096013A1 (en) * 2000-12-22 2003-05-22 Jane Werling Preparation of submicron sized particles with polymorph control
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US20040256749A1 (en) * 2000-12-22 2004-12-23 Mahesh Chaubal Process for production of essentially solvent-free small particles
US7193084B2 (en) * 2000-12-22 2007-03-20 Baxter International Inc. Polymorphic form of itraconazole
US6884436B2 (en) * 2000-12-22 2005-04-26 Baxter International Inc. Method for preparing submicron particle suspensions
US6607784B2 (en) * 2000-12-22 2003-08-19 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US20050048126A1 (en) * 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
US7033348B2 (en) * 2001-04-10 2006-04-25 The Research Foundation Of The City University Of New York Gelatin based on Power-gel™ as solders for Cr4+laser tissue welding and sealing of lung air leak and fistulas in organs
MXPA04002446A (es) * 2001-09-26 2004-07-23 Baxter Int Preparacion de nanoparticulas de tamano de submicras mediante dispersion y remocion de la fase liquida o solvente.
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
US7112340B2 (en) * 2001-10-19 2006-09-26 Baxter International Inc. Compositions of and method for preparing stable particles in a frozen aqueous matrix
AU2003223852A1 (en) 2002-02-28 2003-09-09 Wolf-Dieter Juelich Micro/nanoparticle obtained from lipid-containing marine organisms for use in pharmaceutics and cosmetics
CA2476859C (en) * 2002-03-13 2011-09-20 Collagenex Pharmaceuticals, Inc. Water-based delivery systems
ITMI20022323A1 (it) * 2002-10-31 2004-05-01 Maria Rosa Gasco Composizioni farmaceutiche atte al trattamento di malattie oftalmiche.
JP2007520555A (ja) * 2004-02-05 2007-07-26 バクスター・インターナショナル・インコーポレイテッド 自己安定化剤の使用により調製された分散剤
JP2008543842A (ja) * 2005-06-14 2008-12-04 バクスター インターナショナル インコーポレイテッド 薬物−薬物相互作用を最小にするための薬学的処方物
US20060280787A1 (en) * 2005-06-14 2006-12-14 Baxter International Inc. Pharmaceutical formulation of the tubulin inhibitor indibulin for oral administration with improved pharmacokinetic properties, and process for the manufacture thereof
CN101309669A (zh) * 2005-11-15 2008-11-19 巴克斯特国际公司 脂氧合酶抑制剂的组合物
US20070154403A1 (en) * 2006-01-05 2007-07-05 Thomas Skold Oral, Pulmonary and Transmucosal Delivery Composition
US20090152176A1 (en) * 2006-12-23 2009-06-18 Baxter International Inc. Magnetic separation of fine particles from compositions
US8426467B2 (en) * 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
US8722736B2 (en) * 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
US20080293814A1 (en) * 2007-05-22 2008-11-27 Deepak Tiwari Concentrate esmolol
ITTO20070411A1 (it) * 2007-06-08 2008-12-09 Univ Degli Studi Torino Metodo per la preparazione di micro e nanoparticelle lipidiche solide
US20090061009A1 (en) * 2007-08-29 2009-03-05 Joseph Schwarz Composition and Method of Treatment of Bacterial Infections
DE102008035442A1 (de) 2008-07-26 2010-01-28 Ernst-Moritz-Arndt-Universität Greifswald Zubereitungen aus Artemisia Annua, ihre Umwandlung in Mikro- und Nanopartikel und ihre Verwendung
US9907758B2 (en) 2012-01-09 2018-03-06 Panjab University Department Of Biotechnology (Dbt) Process for preparing solid lipid sustained release nanoparticles for delivery of vitamins
CA2950741C (en) * 2014-05-30 2023-03-28 Oms Investments, Inc. Nano-sized water-based dispersion compositions and methods of making thereof
CA2974196C (en) 2015-01-20 2023-12-12 TetraDerm Group LLC Versatile topical drug delivery vehicle and multifactorial tissue moisturizer that provides mucosal and skin barrier restoration

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985354A (en) * 1995-06-07 1999-11-16 Brown University Research Foundation Preparation of multiwall polymeric microcapsules from hydrophilic polymers
IT1240317B (it) * 1990-02-22 1993-12-07 Maria Rosa Gasco Microsfere lipidiche solide a stretto intervallo dimensionale e relativo procedimento di preparazione
US5145684A (en) * 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
US5250236A (en) * 1991-08-05 1993-10-05 Gasco Maria R Method for producing solid lipid microspheres having a narrow size distribution
CA2091152C (en) * 1993-03-05 2005-05-03 Kirsten Westesen Solid lipid particles, particles of bioactive agents and methods for the manfuacture and use thereof
US5744155A (en) * 1993-08-13 1998-04-28 Friedman; Doron Bioadhesive emulsion preparations for enhanced drug delivery

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102013224627A1 (de) * 2013-11-29 2015-06-03 Andreas Lauterbach Pharmazeutische Formulierung mit Lipidmikropartikeln und Herstellungsverfahren

Also Published As

Publication number Publication date
WO1998056362A1 (en) 1998-12-17
IT1292142B1 (it) 1999-01-25
CA2294172C (en) 2007-01-09
ATE235897T1 (de) 2003-04-15
EP0988031A1 (de) 2000-03-29
DE69812936D1 (de) 2003-05-08
EP0988031B1 (de) 2003-04-02
ITMI971385A0 (de) 1997-06-12
ITMI971385A1 (it) 1998-12-12
CA2294172A1 (en) 1998-12-17
AU7915898A (en) 1998-12-30
US6238694B1 (en) 2001-05-29

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