ES2073688T3 - Rotogranulaciones y revestimiento de enmascaramiento del sabor para la preparacion de tabletas farmaceuticas masticables. - Google Patents
Rotogranulaciones y revestimiento de enmascaramiento del sabor para la preparacion de tabletas farmaceuticas masticables.Info
- Publication number
- ES2073688T3 ES2073688T3 ES91307913T ES91307913T ES2073688T3 ES 2073688 T3 ES2073688 T3 ES 2073688T3 ES 91307913 T ES91307913 T ES 91307913T ES 91307913 T ES91307913 T ES 91307913T ES 2073688 T3 ES2073688 T3 ES 2073688T3
- Authority
- ES
- Spain
- Prior art keywords
- rotogranulations
- preparation
- pharmaceutical tablets
- masking coating
- flavor masking
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A61K9/0058—Chewing gums
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LAS TABLETAS DE MEDICAMENTOS MASTICABLES SE HACEN DE ROTOGRANULADOS REVESTIDOS DE UN MEDICAMENTO EN EL QUE SE FORMAN LOS ROTOGRANULOS DE UNA MEZCLA DE GRANULACION DEL MEDICAMENTO V. GR. LIGADOR FAMOTIDINA, V. GR. POLIVINILPIRROLIDONA, Y PORTADOR, V. GR. LACTOSA Y LOS ROTOGRANULADOS SE REVISTEN CON ACETATO DE CELULOSA, BUTIRATO ACETATO DE CELULOSA O UNA COMBINACION DE LOS MISMOS Y POLIVINIL PIRROLIDONA Y UN PROCESO PARA ELABORAR DICHAS TABLETAS Y UN METODO DE ENMASCARAR EL GUSTO DE LOS MEDICAMENTOS UTILIZANDO TALES ROTOGRANULOS REVESTIDOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57546590A | 1990-08-30 | 1990-08-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2073688T3 true ES2073688T3 (es) | 1995-08-16 |
Family
ID=24300440
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91307913T Expired - Lifetime ES2073688T3 (es) | 1990-08-30 | 1991-08-29 | Rotogranulaciones y revestimiento de enmascaramiento del sabor para la preparacion de tabletas farmaceuticas masticables. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0473431B1 (es) |
JP (1) | JP3221891B2 (es) |
KR (1) | KR100214792B1 (es) |
AU (1) | AU633757B2 (es) |
CA (1) | CA2052679C (es) |
DE (1) | DE69108143T2 (es) |
ES (1) | ES2073688T3 (es) |
MX (1) | MX9100856A (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2079934C (en) * | 1991-10-15 | 2002-09-03 | Edward J. Roche | Taste mask coatings for preparing chewable pharmaceutical tablets |
GB9221414D0 (en) * | 1992-10-13 | 1992-11-25 | Glaxo Group Ltd | Pharmaceutical compositions |
CA2110313C (en) * | 1992-12-01 | 2004-10-26 | Edward John Roche | Pharmaceutical compositions containing a guanidinothiazole compound and antacids |
US5523095A (en) * | 1993-12-15 | 1996-06-04 | Eastman Chemical Company | Controlled release matrix system using cellulose acetate/polyvinylpyrrolidone blends |
US5536505A (en) * | 1993-12-15 | 1996-07-16 | Eastman Chemical Company | Controlled release matrix system using cellulose acetate/poly-2-ethyl-2-oxazoline blends |
US5529783A (en) * | 1994-12-19 | 1996-06-25 | Mcneil-Ppc, Inc. | Rotor granulation and coating of acetaminophen, pseudoephedrine, chlorpheniramine, and, optionally dextromethorphan |
UA65607C2 (uk) * | 1998-03-04 | 2004-04-15 | Орто-Макнейл Фармацевтикал, Інк. | Фармацевтична композиція (варіанти) та спосіб її приготування |
JP4711478B2 (ja) * | 1999-08-13 | 2011-06-29 | 旭化成ケミカルズ株式会社 | 味がマスクされた薬物 |
EP1679066A4 (en) * | 2003-10-27 | 2011-06-22 | Astellas Pharma Inc | MEDICINAL COATING MICROPARTICLES FOR A MOUTH-DISABLE TABLET |
RU2359670C2 (ru) | 2004-03-25 | 2009-06-27 | Астеллас Фарма Инк. | Композиция солифенацина или его соли для использования в твердом препарате |
US7815939B2 (en) | 2005-07-20 | 2010-10-19 | Astellas Pharma Inc. | Coated fine particles containing drug for intrabuccally fast disintegrating dosage forms |
WO2007010930A1 (ja) * | 2005-07-20 | 2007-01-25 | Astellas Pharma Inc. | 口腔内崩壊製剤用の薬物含有被覆微粒子及びその製造方法 |
CN109432291A (zh) * | 2018-11-28 | 2019-03-08 | 哈尔滨新海德智能环境工程有限公司 | 一种中医慢性病缓释调理咀嚼颗粒 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE861284L (en) * | 1986-05-14 | 1987-11-14 | Birex Res And Dev Ltd And Carm | Controlled release ketoprofen. |
NZ226822A (en) * | 1987-11-16 | 1990-03-27 | Mcneil Consumer Prod | Chewable medicament tablet containing means for taste masking |
GB8805695D0 (en) * | 1988-03-10 | 1988-04-07 | Nycomed As | Enteric coated spheroidal granules |
DE68903605T2 (de) * | 1988-05-04 | 1993-04-01 | Smith Kline French Lab | Kautablette. |
-
1991
- 1991-08-21 CA CA002052679A patent/CA2052679C/en not_active Expired - Lifetime
- 1991-08-28 AU AU83497/91A patent/AU633757B2/en not_active Expired
- 1991-08-28 MX MX9100856A patent/MX9100856A/es not_active IP Right Cessation
- 1991-08-29 JP JP24236191A patent/JP3221891B2/ja not_active Expired - Fee Related
- 1991-08-29 DE DE69108143T patent/DE69108143T2/de not_active Expired - Lifetime
- 1991-08-29 EP EP91307913A patent/EP0473431B1/en not_active Expired - Lifetime
- 1991-08-29 ES ES91307913T patent/ES2073688T3/es not_active Expired - Lifetime
- 1991-08-29 KR KR1019910014995A patent/KR100214792B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2052679A1 (en) | 1992-03-01 |
DE69108143D1 (de) | 1995-04-20 |
KR920003966A (ko) | 1992-03-27 |
EP0473431B1 (en) | 1995-03-15 |
DE69108143T2 (de) | 1995-07-20 |
JP3221891B2 (ja) | 2001-10-22 |
MX9100856A (es) | 1992-04-01 |
KR100214792B1 (ko) | 1999-08-02 |
EP0473431A1 (en) | 1992-03-04 |
AU8349791A (en) | 1992-03-05 |
AU633757B2 (en) | 1993-02-04 |
CA2052679C (en) | 1997-12-02 |
JPH06219939A (ja) | 1994-08-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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