NO178564C - Framgangsmåte for framstilling av et system for administrering av aktive medikamenter gjennom slimhinner - Google Patents

Framgangsmåte for framstilling av et system for administrering av aktive medikamenter gjennom slimhinner

Info

Publication number
NO178564C
NO178564C NO890283A NO890283A NO178564C NO 178564 C NO178564 C NO 178564C NO 890283 A NO890283 A NO 890283A NO 890283 A NO890283 A NO 890283A NO 178564 C NO178564 C NO 178564C
Authority
NO
Norway
Prior art keywords
mucosa
preparing
active drugs
administering active
administering
Prior art date
Application number
NO890283A
Other languages
English (en)
Other versions
NO890283L (no
NO890283D0 (no
NO178564B (no
Inventor
Lisbeth Illum
Original Assignee
Danbiosyst Uk Ltd
Cosmas Damian Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danbiosyst Uk Ltd, Cosmas Damian Ltd filed Critical Danbiosyst Uk Ltd
Publication of NO890283L publication Critical patent/NO890283L/no
Publication of NO890283D0 publication Critical patent/NO890283D0/no
Publication of NO178564B publication Critical patent/NO178564B/no
Publication of NO178564C publication Critical patent/NO178564C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NO890283A 1987-05-22 1989-01-23 Framgangsmåte for framstilling av et system for administrering av aktive medikamenter gjennom slimhinner NO178564C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878712176A GB8712176D0 (en) 1987-05-22 1987-05-22 Drug delivery system
PCT/GB1988/000396 WO1988009163A1 (en) 1987-05-22 1988-05-20 Enhanced uptake drug delivery system

Publications (4)

Publication Number Publication Date
NO890283L NO890283L (no) 1989-01-23
NO890283D0 NO890283D0 (no) 1989-01-23
NO178564B NO178564B (no) 1996-01-15
NO178564C true NO178564C (no) 1996-04-24

Family

ID=10617794

Family Applications (1)

Application Number Title Priority Date Filing Date
NO890283A NO178564C (no) 1987-05-22 1989-01-23 Framgangsmåte for framstilling av et system for administrering av aktive medikamenter gjennom slimhinner

Country Status (10)

Country Link
EP (1) EP0391896B1 (no)
JP (1) JP2914670B2 (no)
AU (1) AU614290B2 (no)
CA (1) CA1324079C (no)
DE (1) DE3888201T2 (no)
DK (1) DK175316B1 (no)
FI (1) FI97444C (no)
GB (2) GB8712176D0 (no)
NO (1) NO178564C (no)
WO (1) WO1988009163A1 (no)

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US5811128A (en) * 1986-10-24 1998-09-22 Southern Research Institute Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor
US5075109A (en) * 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
US5298243A (en) * 1988-10-20 1994-03-29 Denki Kagaku Kogyo Kabushiki Kaisha Colony stimulating factor-gelatin conjugate
DK0458894T3 (da) * 1989-02-17 1996-10-07 Liposome Co Inc Lipidexcipiens til nasal afgivelse og topisk påføring
US5554388A (en) * 1989-02-25 1996-09-10 Danbiosyst Uk Limited Systemic drug delivery compositions comprising a polycationi substance
JPH04504258A (ja) * 1989-03-29 1992-07-30 アルコン　ラボラトリーズ　インコーポレイテッド モノアシルホスホグリセリド類を使用して眼薬の角膜への浸透を増強する方法
GB8918879D0 (en) * 1989-08-18 1989-09-27 Danbiosyst Uk Pharmaceutical compositions
US5725871A (en) * 1989-08-18 1998-03-10 Danbiosyst Uk Limited Drug delivery compositions comprising lysophosphoglycerolipid
GB2237510B (en) * 1989-11-04 1993-09-15 Danbiosyst Uk Small particle drug compositions for nasal administration
US5707644A (en) * 1989-11-04 1998-01-13 Danbiosyst Uk Limited Small particle compositions for intranasal drug delivery
GB9001635D0 (en) * 1990-01-24 1990-03-21 Ganderton David Aerosol carriers
GB9012663D0 (en) 1990-06-07 1990-08-01 Erba Carlo Spa Galenic formulations containing cyclodextrins
DK49791D0 (da) * 1991-03-20 1991-03-20 Novo Nordisk As Nasalt pulverpraeparat
IT1247472B (it) * 1991-05-31 1994-12-17 Fidia Spa Processo per la preparazione di microsfere contenenti componenti biologicamente attivi.
EP0566135A1 (en) * 1992-04-17 1993-10-20 Takeda Chemical Industries, Ltd. Transmucosal composition comprising a peptide and a cytidine derivative
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
CA2150803C (en) * 1992-12-02 2006-01-31 Henry Auer Controlled release growth hormone containing microspheres
US5549908A (en) * 1993-05-20 1996-08-27 The University Of Akron Hydrolytically labile microspheres of polysaccharide crosslinked with cyanogen halide and their application in wound dressings
IS1796B (is) * 1993-06-24 2001-12-31 Ab Astra Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
US5830853A (en) * 1994-06-23 1998-11-03 Astra Aktiebolag Systemic administration of a therapeutic preparation
US5747445A (en) * 1993-06-24 1998-05-05 Astra Aktiebolag Therapeutic preparation for inhalation
SE9302198D0 (sv) * 1993-06-24 1993-06-24 Ab Astra Powder preparation for inhalation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
US5506203C1 (en) * 1993-06-24 2001-02-06 Astra Ab Systemic administration of a therapeutic preparation
TW402506B (en) * 1993-06-24 2000-08-21 Astra Ab Therapeutic preparation for inhalation
SE9303574D0 (sv) * 1993-11-01 1993-11-01 Kabi Pharmacia Ab Composition for drug delivery and method the manufacturing thereof
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
JPH10501519A (ja) 1994-03-07 1998-02-10 インヘイル・セラピューティック・システムズ インシュリンを肺に送給できる方法および組成物
US6165976A (en) * 1994-06-23 2000-12-26 Astra Aktiebolag Therapeutic preparation for inhalation
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
KR100389080B1 (ko) 1994-12-22 2003-10-17 아스트라제네카 악티에볼라그 부갑상선호르몬(pth)을포함하는흡입용치료제제
NZ298169A (en) 1994-12-22 1999-09-29 Astra Ab Aerosol drug formulation; comprises hydrofluoroalkane propellant, medicament for inhalation and a surfactant
GB9522351D0 (en) * 1995-11-01 1996-01-03 Medeva Holdings Bv Vaccine compositions
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US5985309A (en) * 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
US20020052310A1 (en) 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
GB9700624D0 (en) 1997-01-14 1997-03-05 Danbiosyst Uk Drug delivery composition
US6391452B1 (en) 1997-07-18 2002-05-21 Bayer Corporation Compositions for nasal drug delivery, methods of making same, and methods of removing residual solvent from pharmaceutical preparations
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
US6946117B1 (en) 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6433040B1 (en) 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
JP2000290184A (ja) * 1999-04-01 2000-10-17 Kyowa Hakko Kogyo Co Ltd 経鼻投与製剤
US7833549B2 (en) * 2000-01-19 2010-11-16 Mannkind Corporation Dry powder formulations of antihistamine for nasal administration
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
CA2382133C (en) 2000-05-10 2010-11-23 Alliance Pharmaceutical Corporation Phospholipid-based powders for drug delivery
GB0027357D0 (en) 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
AU2002230993B2 (en) 2000-12-29 2006-02-02 Alkermes, Inc. Particles for inhalation having sustained release properties
WO2003026699A1 (fr) * 2001-09-26 2003-04-03 Tanabe Seiyaku Co., Ltd. Compositions medicinales favorisant l'absorption de medicaments
ES2415654T3 (es) 2001-11-20 2013-07-26 Civitas Therapeutics, Inc. Composiciones particuladas mejoradas para suministro pulmonar
EP1458360B1 (en) 2001-12-19 2011-05-11 Novartis AG Pulmonary delivery of aminoglycosides
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
NL1022442C2 (nl) * 2003-01-20 2004-07-22 Tno Toepassing van lipide ter verbetring van de opname van nutrienten en (farmaceutisch) actieve stoffen.
US7591999B2 (en) * 2003-03-04 2009-09-22 Mitsubishi Tanabe Pharma Corporation Powdery preparation for nasal administration
CA2528465A1 (en) * 2003-06-09 2005-01-20 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery of growth hormone
MX350838B (es) 2011-02-11 2017-09-18 Grain Proc Corporation * Composicion de sal.
PL3099293T3 (pl) 2014-01-27 2021-06-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Nanokapsułkowanie hydrofilowych związków aktywnych

Family Cites Families (4)

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Publication number Priority date Publication date Assignee Title
US3681500A (en) * 1969-12-12 1972-08-01 Boehringer Sohn Ingelheim Spray compositions for treatment of obstructive disorders of the respiratory tract and methods therefor
JPS59163313A (ja) 1983-03-09 1984-09-14 Teijin Ltd 経鼻投与用ペプチドホルモン類組成物
GB8514090D0 (en) * 1985-06-04 1985-07-10 Sandoz Ltd Organic compounds
NZ221411A (en) * 1986-08-11 1989-10-27 Innovata Biomed Ltd Pharmaceutical compositions containing microcapsules and a surfactant

Also Published As

Publication number Publication date
NO890283L (no) 1989-01-23
DK175316B1 (da) 2004-08-16
EP0391896B1 (en) 1994-03-02
CA1324079C (en) 1993-11-09
NO890283D0 (no) 1989-01-23
GB8924696D0 (en) 1990-09-05
DE3888201T2 (de) 1994-07-14
FI895555A0 (fi) 1989-11-21
DE3888201D1 (de) 1994-04-07
GB2231495A (en) 1990-11-21
FI97444B (fi) 1996-09-13
GB8712176D0 (en) 1987-06-24
WO1988009163A1 (en) 1988-12-01
DK583789D0 (da) 1989-11-21
GB2231495B (en) 1991-08-28
DK583789A (da) 1990-01-18
AU614290B2 (en) 1991-08-29
AU1793188A (en) 1988-12-21
FI97444C (fi) 1996-12-27
EP0391896A1 (en) 1990-10-17
JP2914670B2 (ja) 1999-07-05
NO178564B (no) 1996-01-15
JPH02503915A (ja) 1990-11-15

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