MW5886A1 - Substituted bridged-diazabicycloalkyl quinolone carboxylic acids - Google Patents

Substituted bridged-diazabicycloalkyl quinolone carboxylic acids

Info

Publication number
MW5886A1
MW5886A1 MW58/86A MW5886A MW5886A1 MW 5886 A1 MW5886 A1 MW 5886A1 MW 58/86 A MW58/86 A MW 58/86A MW 5886 A MW5886 A MW 5886A MW 5886 A1 MW5886 A1 MW 5886A1
Authority
MW
MALAWI
Prior art keywords
carboxylic acids
quinolone carboxylic
substituted bridged
diazabicycloalkyl
alkyl
Prior art date
Application number
MW58/86A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MW5886A1 publication Critical patent/MW5886A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Materials For Photolithography (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
MW58/86A 1985-09-18 1986-08-28 Substituted bridged-diazabicycloalkyl quinolone carboxylic acids MW5886A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77747185A 1985-09-18 1985-09-18

Publications (1)

Publication Number Publication Date
MW5886A1 true MW5886A1 (en) 1987-12-09

Family

ID=25110350

Family Applications (1)

Application Number Title Priority Date Filing Date
MW58/86A MW5886A1 (en) 1985-09-18 1986-08-28 Substituted bridged-diazabicycloalkyl quinolone carboxylic acids

Country Status (42)

Country Link
US (3) US4861779A (zh)
EP (1) EP0215650B1 (zh)
JP (1) JPH0798819B2 (zh)
KR (1) KR870000961B1 (zh)
CN (1) CN1014789B (zh)
AT (1) ATE72245T1 (zh)
AU (1) AU576302B2 (zh)
BG (2) BG49275A3 (zh)
CA (1) CA1340734C (zh)
CY (1) CY1774A (zh)
CZ (1) CZ277825B6 (zh)
DD (1) DD259190A5 (zh)
DE (2) DE19675019I2 (zh)
DK (1) DK171276B1 (zh)
EG (1) EG18184A (zh)
ES (1) ES2001428A6 (zh)
FI (1) FI87565C (zh)
GR (1) GR862363B (zh)
HK (1) HK132795A (zh)
HU (1) HU200462B (zh)
IE (1) IE58966B1 (zh)
IL (1) IL80033A (zh)
IN (1) IN166416B (zh)
LU (1) LU90356I2 (zh)
MA (1) MA20770A1 (zh)
MW (1) MW5886A1 (zh)
MX (1) MX173358B (zh)
MY (1) MY102518A (zh)
NO (1) NO170335C (zh)
NZ (1) NZ217614A (zh)
OA (1) OA08410A (zh)
PH (2) PH24048A (zh)
PL (1) PL149987B1 (zh)
PT (1) PT83388B (zh)
SG (1) SG28094G (zh)
SK (1) SK667886A3 (zh)
SU (1) SU1482531A3 (zh)
UA (1) UA6340A1 (zh)
YU (1) YU45024B (zh)
ZA (1) ZA867063B (zh)
ZM (1) ZM8586A1 (zh)
ZW (1) ZW19386A1 (zh)

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US4965273A (en) * 1986-10-08 1990-10-23 Bristol-Myers Company Certain 1-tertiary-butyl-naphthyridone carboxylic acid derivatives anti-bacterial agents
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US4923879A (en) * 1987-07-31 1990-05-08 Warner-Lambert Company 1,8-Naphthyridines and their use as antibacterial agents
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US5147873A (en) * 1988-08-23 1992-09-15 Pfizer Inc. Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters
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US5036153A (en) * 1989-05-11 1991-07-30 Braish Tamim F Preparation of 2,5-diazabicyclo[2.2.1]heptanes and intermediates
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US5929086A (en) 1996-05-10 1999-07-27 Pharmacia & Upjohn Company Topical administration of antimicrobial agents for the treatment of systemic bacterial diseases
US6056436A (en) * 1997-02-20 2000-05-02 University Of Maryland Simultaneous measurement of temperature and strain using optical sensors
WO2000066586A1 (en) * 1999-05-04 2000-11-09 Neurosearch A/S Heteroaryl diazabicycloalkanes, their preparation and use
FR2809730B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo Derives de 1,4-diazabicyclo[3.2.2] nonanebenzoxazole, -benzothiazole et -benzimidazole, leur preparation et leur application therapeutique
FR2809731B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo Derives de 1,4-diazabicyclo-[3.2.2] nonane-pheylisoxazole, leur preparation et leur application en therapeutique
FR2809732B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo DERIVES DE 4(-2-PHENYLTHIAZOL-5-yl)-1,4-DIAZABICYCLO-[3.2.2] NONANE, LEUR PREPARATION ET LEUR APPLICATION ENTHERAPEUTIQUE
ATE287404T1 (de) * 2001-03-02 2005-02-15 Neurosearch As Diazabicyclo (2.2.1) heptanderivate
EP1551843A1 (en) * 2002-09-10 2005-07-13 Pfizer Products Inc. Diazabicyclic compounds useful in the treatment of cns and other disorders
EP1543000B1 (en) * 2002-09-25 2013-03-06 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof
DE10312346A1 (de) * 2003-03-20 2004-09-30 Bayer Healthcare Ag Kontrolliertes Freisetzungssystem
DE10351448A1 (de) 2003-11-04 2005-06-09 Bayer Healthcare Ag Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
EP1697378B1 (en) * 2003-12-22 2007-11-21 Memory Pharmaceuticals Corporation Indoles, 1h-indazoles, 1,2-benzisoxazoles, and 1,2-benzisothiazoles, and preparation and uses thereof
CN103724343A (zh) 2004-03-25 2014-04-16 记忆药物公司 吲唑、苯并噻唑、苯并异噻唑、苯并异噁唑及其制备和用途
WO2006001894A1 (en) * 2004-04-22 2006-01-05 Memory Pharmaceutical Corporation Indoles, 1h-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof
AU2005243147A1 (en) * 2004-05-07 2005-11-24 Memory Pharmaceuticals Corporation 1H-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles, and chromones and preparation and uses thereof
DE102005055385A1 (de) * 2004-12-09 2006-06-14 Bayer Healthcare Ag Arzneimittel zur hygienischen Applikation im Ohr
DE602005019094D1 (de) 2004-12-22 2010-03-11 Memory Pharmaceutical Corp Nikotinische alpha-7-rezeptorliganden gegen erkrankungen des zns
US8106066B2 (en) * 2005-09-23 2012-01-31 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
US7687517B2 (en) 2006-02-10 2010-03-30 Neurosearch A/S 3,9-Diazabicyclo [3.3.1] nonane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
CN101379063A (zh) 2006-02-10 2009-03-04 神经研究公司 3,9-二氮杂双环[3.3.1]壬烷衍生物及其作为单胺神经递质再摄取抑制剂的用途
US7687523B2 (en) 2006-02-10 2010-03-30 Neurosearch A/S 3-heteroaryl-3,9-diazabicyclo[3.3.1]nonane derivatives as nicotinic acetylcholine receptor agonists
DE102006010642A1 (de) * 2006-03-08 2007-09-27 Bayer Healthcare Aktiengesellschaft Arzneimittelformulierungen, enthaltend Fluorchinolone
DE102006010643A1 (de) 2006-03-08 2007-09-13 Bayer Healthcare Aktiengesellschaft Arzneimittel enthaltend Fluorchinolone
DE102007026550A1 (de) * 2007-06-08 2008-12-11 Bayer Healthcare Ag Extrudate mit verbesserter Geschmacksmaskierung
DE102007055341A1 (de) * 2007-11-19 2009-05-20 Bayer Animal Health Gmbh Stabilisierung öliger Suspensionen enthaltend hydrophobe Kieselsäuren
WO2009111680A1 (en) * 2008-03-07 2009-09-11 Smithline Beecham Corporation Trpv4 antagonists
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DE3641312A1 (de) * 1986-12-03 1988-06-09 Bayer Ag Verfahren zur herstellung von chinolincarbonsaeuren
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US4851418A (en) * 1987-08-21 1989-07-25 Warner-Lambert Company Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent

Also Published As

Publication number Publication date
FI87565C (fi) 1993-01-25
IE862479L (en) 1987-03-18
HU200462B (en) 1990-06-28
YU161786A (en) 1987-10-31
CN1014789B (zh) 1991-11-20
JPH0798819B2 (ja) 1995-10-25
ZA867063B (en) 1988-04-27
LU90356I2 (fr) 1999-04-26
PT83388A (en) 1986-10-01
PL149987B1 (en) 1990-04-30
UA6340A1 (uk) 1994-12-29
BG49275A3 (en) 1991-09-16
CA1340734C (en) 1999-09-14
EP0215650A3 (en) 1987-12-02
US4861779A (en) 1989-08-29
DK171276B1 (da) 1996-08-19
NO170335C (no) 1992-10-07
MY102518A (en) 1992-07-31
SG28094G (en) 1994-10-28
FI863756A (fi) 1987-03-19
NO170335B (no) 1992-06-29
YU45024B (en) 1991-06-30
PH24048A (en) 1990-03-05
IL80033A (en) 1992-05-25
MA20770A1 (fr) 1987-04-01
ES2001428A6 (es) 1988-05-16
US4775668A (en) 1988-10-04
KR870003106A (ko) 1987-04-15
MX173358B (es) 1994-02-23
BG61091B2 (bg) 1996-10-31
ZM8586A1 (en) 1987-03-27
CY1774A (en) 1995-10-20
ATE72245T1 (de) 1992-02-15
FI863756A0 (fi) 1986-09-17
NZ217614A (en) 1989-11-28
DK445886A (da) 1987-05-27
EP0215650A2 (en) 1987-03-25
HUT43070A (en) 1987-09-28
IL80033A0 (en) 1986-12-31
CZ277825B6 (en) 1993-06-16
PH25338A (en) 1991-04-30
KR870000961B1 (ko) 1987-05-14
ZW19386A1 (en) 1986-12-10
JPS62103083A (ja) 1987-05-13
IE58966B1 (en) 1993-12-01
AU6276886A (en) 1987-03-19
EP0215650B1 (en) 1992-01-29
HK132795A (en) 1995-09-01
MX3751A (es) 1993-09-01
SU1482531A3 (ru) 1989-05-23
PL261410A1 (en) 1987-11-16
IN166416B (zh) 1990-05-05
DE3683711D1 (de) 1992-03-12
AU576302B2 (en) 1988-08-18
NO863718L (no) 1987-03-19
CN86106385A (zh) 1987-06-03
DE19675019I2 (de) 2004-01-29
GR862363B (en) 1987-01-19
OA08410A (fr) 1988-06-30
DD259190A5 (de) 1988-08-17
PT83388B (pt) 1989-05-12
FI87565B (fi) 1992-10-15
NO863718D0 (no) 1986-09-17
US5091383A (en) 1992-02-25
CZ667886A3 (en) 1993-02-17
DK445886D0 (da) 1986-09-17
SK278605B6 (en) 1997-11-05
EG18184A (en) 1992-12-30
SK667886A3 (en) 1997-11-05

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