MEP43808A - Polymer conjugates of mutated neublastin - Google Patents
Polymer conjugates of mutated neublastinInfo
- Publication number
- MEP43808A MEP43808A MEP-438/08A MEP43808A MEP43808A ME P43808 A MEP43808 A ME P43808A ME P43808 A MEP43808 A ME P43808A ME P43808 A MEP43808 A ME P43808A
- Authority
- ME
- Montenegro
- Prior art keywords
- polymer conjugates
- mutated neublastin
- neublastin
- polymer
- prolonged
- Prior art date
Links
- 102100026376 Artemin Human genes 0.000 title abstract 3
- 101000785776 Homo sapiens Artemin Proteins 0.000 title abstract 2
- 229920000642 polymer Polymers 0.000 title abstract 2
- 239000000539 dimer Substances 0.000 abstract 2
- 230000002035 prolonged effect Effects 0.000 abstract 2
- 230000004071 biological effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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- A—HUMAN NECESSITIES
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
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- A—HUMAN NECESSITIES
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A—HUMAN NECESSITIES
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- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/4756—Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Psychology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/356,264 US7442370B2 (en) | 2001-02-01 | 2003-01-31 | Polymer conjugates of mutated neublastin |
PCT/US2004/002763 WO2004069176A2 (en) | 2001-02-01 | 2004-02-02 | Polymer conjugates of mutated neublastin |
YU20050585A RS52910B (en) | 2003-01-31 | 2004-02-02 | POLYMER CONJUGATES OF MUTATED NEUBLASTINE |
Publications (1)
Publication Number | Publication Date |
---|---|
MEP43808A true MEP43808A (en) | 2011-02-10 |
Family
ID=35006489
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MEP-438/08A MEP43808A (en) | 2003-01-31 | 2004-02-02 | Polymer conjugates of mutated neublastin |
Country Status (27)
Country | Link |
---|---|
EP (3) | EP2301960A3 (ru) |
JP (3) | JP4742025B2 (ru) |
KR (2) | KR101293805B1 (ru) |
CN (2) | CN101166753A (ru) |
AT (1) | ATE478891T1 (ru) |
AU (1) | AU2004209966B9 (ru) |
BR (1) | BRPI0407170A (ru) |
CA (1) | CA2514510C (ru) |
CY (2) | CY1111196T1 (ru) |
DE (1) | DE602004028801D1 (ru) |
DK (2) | DK2246362T3 (ru) |
EA (1) | EA008743B1 (ru) |
ES (2) | ES2450115T3 (ru) |
GE (3) | GEP20135982B (ru) |
HK (1) | HK1085663A1 (ru) |
IL (2) | IL169945A (ru) |
IS (1) | IS7938A (ru) |
ME (1) | MEP43808A (ru) |
MX (1) | MXPA05008168A (ru) |
NO (1) | NO20054025L (ru) |
NZ (2) | NZ581460A (ru) |
PL (1) | PL383683A1 (ru) |
PT (2) | PT1594436E (ru) |
RS (1) | RS52910B (ru) |
SI (2) | SI1594436T1 (ru) |
UA (2) | UA91178C2 (ru) |
ZA (1) | ZA200505707B (ru) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA91178C2 (ru) * | 2003-01-31 | 2010-07-12 | Байоджен Айдек Ма Інк. | Мутантный неубластин |
WO2006023782A2 (en) * | 2004-08-19 | 2006-03-02 | Biogen Ideca Ma Inc. | Refolding transforming growth factor beta family proteins |
US20140092376A1 (en) * | 2012-10-01 | 2014-04-03 | Momentive Performance Materials, Inc. | Container and method for in-line analysis of protein compositions |
AU2018212403A1 (en) * | 2017-01-25 | 2019-08-22 | Tessa Therapeutics Ltd. | TGF-ß decoy receptor |
EP4096920A1 (en) * | 2020-01-27 | 2022-12-07 | Silcotek Corp. | Biopharmaceutical manufacturing process and product |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU187037B (en) | 1983-04-19 | 1985-10-28 | Tibor Sinko | Rope-stretching device |
EP0154316B1 (en) | 1984-03-06 | 1989-09-13 | Takeda Chemical Industries, Ltd. | Chemically modified lymphokine and production thereof |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
CA2006596C (en) | 1988-12-22 | 2000-09-05 | Rika Ishikawa | Chemically-modified g-csf |
US5252714A (en) | 1990-11-28 | 1993-10-12 | The University Of Alabama In Huntsville | Preparation and use of polyethylene glycol propionaldehyde |
KR100238712B1 (ko) | 1991-06-27 | 2000-01-15 | 스티븐 비. 데이비스 | 씨티엘에이4 수용체,그를 함유한 연합단백질 및 그의 용도 |
CA2092271C (en) | 1993-03-09 | 2009-10-13 | Eddie Reed | Use of g-csf for treating taxol side-effects |
US5834029A (en) | 1994-07-20 | 1998-11-10 | Cytotherapeutics, Inc. | Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment |
US5770577A (en) * | 1994-11-14 | 1998-06-23 | Amgen Inc. | BDNF and NT-3 polypeptides selectively linked to polyethylene glycol |
CA2253871C (en) | 1996-05-08 | 2005-04-26 | Biogen, Inc. | Ret ligand (retl) for stimulating neural and renal growth |
KR100195886B1 (ko) | 1996-11-01 | 1999-06-15 | 김상조 | 당뇨병 치료용 의약조성물 |
ATE375363T1 (de) * | 1997-07-14 | 2007-10-15 | Bolder Biotechnology Inc | Derivate des wachstumshormons und verwandte proteine |
US6593133B1 (en) | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
US20020055467A1 (en) * | 1998-07-06 | 2002-05-09 | Johansen Teit E. | Novel neurotrophic factors |
US20020002269A1 (en) * | 1998-09-29 | 2002-01-03 | Jeffrey D. Milbrandt | Artemin, a neurotrophic factor |
AU2354600A (en) * | 1998-12-09 | 2000-06-26 | Amgen, Inc. | Grnf4 a neurotrophic factor |
IL156559A0 (en) * | 2000-12-22 | 2004-01-04 | Genentech Inc | New use of artemin, a member of the gdnf ligand family |
GEP20063916B (en) * | 2001-02-01 | 2006-09-11 | Biogen Idec Inc | Polymer conjugates of neublastin and methods of using same |
NZ529126A (en) * | 2001-03-28 | 2010-07-30 | Biogen Idec Inc | Use of neublastin polypeptides for treating allodynia, hyperalgesic pain and phantom pain |
UA91178C2 (ru) * | 2003-01-31 | 2010-07-12 | Байоджен Айдек Ма Інк. | Мутантный неубластин |
EP1897552B1 (en) * | 2003-04-18 | 2009-06-17 | Biogen Idec MA Inc. | Polymer-conjugated glycosylated neublastin |
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2004
- 2004-02-02 UA UAA200508412A patent/UA91178C2/ru unknown
- 2004-02-02 EP EP10181704A patent/EP2301960A3/en not_active Withdrawn
- 2004-02-02 CN CNA200480009133XA patent/CN101166753A/zh active Pending
- 2004-02-02 ES ES10173737.7T patent/ES2450115T3/es not_active Expired - Lifetime
- 2004-02-02 GE GEAP200411544A patent/GEP20135982B/en unknown
- 2004-02-02 CA CA2514510A patent/CA2514510C/en not_active Expired - Fee Related
- 2004-02-02 BR BRPI0407170-0A patent/BRPI0407170A/pt not_active IP Right Cessation
- 2004-02-02 UA UAA200912089A patent/UA105892C2/ru unknown
- 2004-02-02 NZ NZ581460A patent/NZ581460A/en not_active IP Right Cessation
- 2004-02-02 SI SI200431548T patent/SI1594436T1/sl unknown
- 2004-02-02 KR KR1020127021783A patent/KR101293805B1/ko not_active IP Right Cessation
- 2004-02-02 MX MXPA05008168A patent/MXPA05008168A/es active IP Right Grant
- 2004-02-02 SI SI200432136T patent/SI2246362T1/sl unknown
- 2004-02-02 DE DE602004028801T patent/DE602004028801D1/de not_active Expired - Lifetime
- 2004-02-02 PT PT04707363T patent/PT1594436E/pt unknown
- 2004-02-02 ME MEP-438/08A patent/MEP43808A/xx unknown
- 2004-02-02 GE GEAP200410236A patent/GEP20115137B/en unknown
- 2004-02-02 GE GEAP20048957A patent/GEP20084464B/en unknown
- 2004-02-02 EP EP10173737.7A patent/EP2246362B1/en not_active Expired - Lifetime
- 2004-02-02 JP JP2006503213A patent/JP4742025B2/ja not_active Expired - Fee Related
- 2004-02-02 CN CN201110239061.XA patent/CN102367277B/zh not_active Expired - Fee Related
- 2004-02-02 AU AU2004209966A patent/AU2004209966B9/en not_active Ceased
- 2004-02-02 AT AT04707363T patent/ATE478891T1/de active
- 2004-02-02 RS YU20050585A patent/RS52910B/en unknown
- 2004-02-02 DK DK10173737.7T patent/DK2246362T3/en active
- 2004-02-02 DK DK04707363.0T patent/DK1594436T3/da active
- 2004-02-02 PT PT101737377T patent/PT2246362E/pt unknown
- 2004-02-02 NZ NZ541921A patent/NZ541921A/en not_active IP Right Cessation
- 2004-02-02 PL PL383683A patent/PL383683A1/pl unknown
- 2004-02-02 EP EP04707363A patent/EP1594436B1/en not_active Expired - Lifetime
- 2004-02-02 KR KR1020057014050A patent/KR101216331B1/ko not_active IP Right Cessation
- 2004-02-02 EA EA200501212A patent/EA008743B1/ru not_active IP Right Cessation
- 2004-02-02 ES ES04707363T patent/ES2351215T3/es not_active Expired - Lifetime
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2005
- 2005-07-12 IS IS7938A patent/IS7938A/is unknown
- 2005-07-15 ZA ZA200505707A patent/ZA200505707B/en unknown
- 2005-07-28 IL IL169945A patent/IL169945A/en not_active IP Right Cessation
- 2005-08-30 NO NO20054025A patent/NO20054025L/no not_active Application Discontinuation
-
2006
- 2006-05-16 HK HK06105655.9A patent/HK1085663A1/xx not_active IP Right Cessation
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2010
- 2010-03-24 JP JP2010069011A patent/JP2010184924A/ja not_active Withdrawn
- 2010-11-23 CY CY20101101050T patent/CY1111196T1/el unknown
-
2011
- 2011-01-17 JP JP2011007339A patent/JP2011078434A/ja not_active Withdrawn
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2013
- 2013-08-01 IL IL227752A patent/IL227752A0/en unknown
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2014
- 2014-03-13 CY CY20141100203T patent/CY1115085T1/el unknown
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