ATE433759T1 - Polymerkonjugiertes glycosiliertes neublastin - Google Patents
Polymerkonjugiertes glycosiliertes neublastinInfo
- Publication number
- ATE433759T1 ATE433759T1 AT07012662T AT07012662T ATE433759T1 AT E433759 T1 ATE433759 T1 AT E433759T1 AT 07012662 T AT07012662 T AT 07012662T AT 07012662 T AT07012662 T AT 07012662T AT E433759 T1 ATE433759 T1 AT E433759T1
- Authority
- AT
- Austria
- Prior art keywords
- neublastin
- polypeptides
- glycosilated
- conjugated
- polymer conjugated
- Prior art date
Links
- 102100026376 Artemin Human genes 0.000 title abstract 5
- 101000785776 Homo sapiens Artemin Proteins 0.000 title abstract 3
- 229920000642 polymer Polymers 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 239000000539 dimer Substances 0.000 abstract 2
- 229920003170 water-soluble synthetic polymer Polymers 0.000 abstract 2
- 230000004071 biological effect Effects 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/4756—Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46389903P | 2003-04-18 | 2003-04-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE433759T1 true ATE433759T1 (de) | 2009-07-15 |
Family
ID=33310837
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07012662T ATE433759T1 (de) | 2003-04-18 | 2004-04-16 | Polymerkonjugiertes glycosiliertes neublastin |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US8163875B2 (de) |
| EP (3) | EP1897552B1 (de) |
| JP (2) | JP4742030B2 (de) |
| AT (1) | ATE433759T1 (de) |
| AU (1) | AU2004233079B2 (de) |
| CA (2) | CA2522364C (de) |
| DE (1) | DE602004021648D1 (de) |
| DK (1) | DK1897552T3 (de) |
| ES (2) | ES2479942T3 (de) |
| NZ (2) | NZ543365A (de) |
| WO (1) | WO2004094592A2 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2783310B2 (ja) | 1993-01-28 | 1998-08-06 | トヨタ車体株式会社 | エンボス成形方法 |
| US7442370B2 (en) | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
| US7276580B2 (en) | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
| US20040077543A1 (en) * | 2001-03-28 | 2004-04-22 | Sah Dinah W. Y. | Treatment using neublastin polypeptides |
| JP4571776B2 (ja) * | 2002-11-05 | 2010-10-27 | Jx日鉱日石エネルギー株式会社 | 潤滑油組成物 |
| ES2351215T3 (es) * | 2003-01-31 | 2011-02-01 | Biogen Idec Ma Inc. | Conjugados poliméricos de neublastina mutada. |
| ATE433759T1 (de) | 2003-04-18 | 2009-07-15 | Biogen Idec Inc | Polymerkonjugiertes glycosiliertes neublastin |
| RU2005138368A (ru) * | 2003-06-10 | 2006-07-27 | ЭнЭсДЖЕНЕ А/С (DK) | Улучшенная секреция нейбластина |
| US7598059B2 (en) | 2003-10-02 | 2009-10-06 | Biogen Idec Ma Inc. | Neublastin expression constructs |
| JP4959566B2 (ja) * | 2004-08-19 | 2012-06-27 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | トランスホーミング増殖因子βファミリータンパク質の折りたたみ |
| EP2335713A3 (de) * | 2004-08-19 | 2011-11-02 | Biogen Idec MA Inc. | Neublastinvarianten |
| EP1937295A2 (de) * | 2005-10-11 | 2008-07-02 | NS Gene A/S | Behandlung von retinopathien mit gfr3-agonisten |
| TWI501774B (zh) | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
| WO2007103182A2 (en) * | 2006-03-01 | 2007-09-13 | Biogen Idec Ma Inc. | Compostions and methods for administering gdnf ligand family proteins |
| JP5583005B2 (ja) * | 2007-05-01 | 2014-09-03 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 血管新生を増大させるための組成物および方法 |
| WO2009020964A2 (en) * | 2007-08-08 | 2009-02-12 | Biogen Idec Ma Inc. | Anti-neublastin antibodies and uses thereof |
| US10317376B2 (en) | 2012-04-11 | 2019-06-11 | Bioverativ Therapeutics Inc. | Methods of detecting glycosaminoglycans |
Family Cites Families (87)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4352883A (en) | 1979-03-28 | 1982-10-05 | Damon Corporation | Encapsulation of biological material |
| US4353888A (en) | 1980-12-23 | 1982-10-12 | Sefton Michael V | Encapsulation of live animal cells |
| US4407957A (en) | 1981-03-13 | 1983-10-04 | Damon Corporation | Reversible microencapsulation of a core material |
| HU187037B (en) | 1983-04-19 | 1985-10-28 | Tibor Sinko | Rope-stretching device |
| EP0154316B1 (de) | 1984-03-06 | 1989-09-13 | Takeda Chemical Industries, Ltd. | Chemisch modifizierte Lymphokine und Verfahren zu ihrer Herstellung |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5525464A (en) | 1987-04-01 | 1996-06-11 | Hyseq, Inc. | Method of sequencing by hybridization of oligonucleotide probes |
| US4883666A (en) | 1987-04-29 | 1989-11-28 | Massachusetts Institute Of Technology | Controlled drug delivery system for treatment of neural disorders |
| US5158881A (en) | 1987-11-17 | 1992-10-27 | Brown University Research Foundation | Method and system for encapsulating cells in a tubular extrudate in separate cell compartments |
| US5283187A (en) | 1987-11-17 | 1994-02-01 | Brown University Research Foundation | Cell culture-containing tubular capsule produced by co-extrusion |
| DE3829752A1 (de) | 1988-09-01 | 1990-03-22 | Akzo Gmbh | Integrale asymmetrische polyaethersulfonmembran, verfahren zur herstellung und verwendung zur ultrafiltration und mikrofiltration |
| DE3829766A1 (de) | 1988-09-01 | 1990-03-22 | Akzo Gmbh | Verfahren zur herstellung von membranen |
| CA2006596C (en) | 1988-12-22 | 2000-09-05 | Rika Ishikawa | Chemically-modified g-csf |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
| US5194596A (en) | 1989-07-27 | 1993-03-16 | California Biotechnology Inc. | Production of vascular endothelial cell growth factor |
| US5350836A (en) | 1989-10-12 | 1994-09-27 | Ohio University | Growth hormone antagonists |
| GB8927546D0 (en) | 1989-12-06 | 1990-02-07 | Ciba Geigy | Process for the production of biologically active tgf-beta |
| US5084350A (en) | 1990-02-16 | 1992-01-28 | The Royal Institution For The Advance Of Learning (Mcgill University) | Method for encapsulating biologically active material including cells |
| US5618531A (en) | 1990-10-19 | 1997-04-08 | New York University | Method for increasing the viability of cells which are administered to the brain or spinal cord |
| US5252714A (en) | 1990-11-28 | 1993-10-12 | The University Of Alabama In Huntsville | Preparation and use of polyethylene glycol propionaldehyde |
| EP0585368B1 (de) | 1991-04-25 | 1997-08-06 | Brown University Research Foundation | Implantierbare, biokompatible immunisolator-trägersubstanz zum abgeben ausgesuchter, therapeutischer produkte |
| ES2284226T3 (es) | 1991-07-02 | 2007-11-01 | Nektar Therapeutics | Dispositivo para proporcionar medicamentos en aerosol. |
| ATE275197T1 (de) | 1991-09-20 | 2004-09-15 | Amgen Inc | Glial neurotrophe faktor |
| US5939524A (en) | 1991-12-09 | 1999-08-17 | The Scripps Research Institute | Platelet GPIII P1A1 and P1A2 epitopes, their preparation and use |
| US5414135A (en) | 1991-12-30 | 1995-05-09 | Sterling Winthrop Inc. | Vinyl sulfone coupling of polyoxyalkylenes to proteins |
| US5785049A (en) | 1994-09-21 | 1998-07-28 | Inhale Therapeutic Systems | Method and apparatus for dispersion of dry powder medicaments |
| DK0679088T3 (da) | 1992-09-29 | 2002-10-28 | Inhale Therapeutic Syst | Pulmonal levering af aktive fragmenter af parathyreoideaea hormon |
| US5349056A (en) | 1992-10-09 | 1994-09-20 | Regeneron Pharmaceuticals | Modified ciliary neurotrophic factors |
| CA2092271C (en) | 1993-03-09 | 2009-10-13 | Eddie Reed | Use of g-csf for treating taxol side-effects |
| EP0802800B1 (de) | 1993-08-12 | 2002-06-12 | Neurotech S.A. | Biokompatible immunoisolatorische Kapseln, die genetisch veränderte Zellen enthalten |
| DE4339605A1 (de) | 1993-11-20 | 1995-05-24 | Beiersdorf Ag | Desodorierende Wirkstoffkombinationen auf der Basis von alpha, omega-Alkandicarbonsäuren und Fettsäurepartialglyceriden |
| US5834029A (en) | 1994-07-20 | 1998-11-10 | Cytotherapeutics, Inc. | Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment |
| US5824784A (en) | 1994-10-12 | 1998-10-20 | Amgen Inc. | N-terminally chemically modified protein compositions and methods |
| US5795716A (en) | 1994-10-21 | 1998-08-18 | Chee; Mark S. | Computer-aided visualization and analysis system for sequence evaluation |
| US5770577A (en) | 1994-11-14 | 1998-06-23 | Amgen Inc. | BDNF and NT-3 polypeptides selectively linked to polyethylene glycol |
| US5780014A (en) | 1995-04-14 | 1998-07-14 | Inhale Therapeutic Systems | Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin |
| US5654007A (en) | 1995-06-07 | 1997-08-05 | Inhale Therapeutic Systems | Methods and system for processing dispersible fine powders |
| US5739307A (en) | 1995-08-28 | 1998-04-14 | Washington University | Polynucleotide encoding neurturin neurotrophic factor |
| US5733729A (en) | 1995-09-14 | 1998-03-31 | Affymetrix, Inc. | Computer-aided probability base calling for arrays of nucleic acid probes on chips |
| US6063757A (en) | 1995-11-29 | 2000-05-16 | Urso; Richard G. | Wound treatment method with nerve growth factor |
| US5641749A (en) | 1995-11-29 | 1997-06-24 | Amgen Inc. | Method for treating retinal ganglion cell injury using glial cell line-derived neurothrophic factor (GDNF) protein product |
| EP0943690B1 (de) | 1995-12-21 | 2006-11-29 | Ajinomoto Co., Inc. | Verfahren zur rückfaltung von menschlichem activin a |
| US6299895B1 (en) | 1997-03-24 | 2001-10-09 | Neurotech S.A. | Device and method for treating ophthalmic diseases |
| US6677135B1 (en) | 1996-05-08 | 2004-01-13 | Biogen, Inc. | Ret ligand (RetL) for stimulating neutral and renal growth |
| US5754524A (en) | 1996-08-30 | 1998-05-19 | Wark; Barry J. | Computerized method and system for analysis of an electrophoresis gel test |
| US6083725A (en) | 1996-09-13 | 2000-07-04 | Transkaryotic Therapies, Inc. | Tranfected human cells expressing human α-galactosidase A protein |
| AU736670B2 (en) | 1996-09-26 | 2001-08-02 | Medical Research Council | Chaperone fragments |
| KR100195886B1 (ko) | 1996-11-01 | 1999-06-15 | 김상조 | 당뇨병 치료용 의약조성물 |
| GB9718908D0 (en) * | 1997-09-05 | 1997-11-12 | Rowett Research Services Limit | Proteins |
| US6653098B1 (en) | 1998-02-23 | 2003-11-25 | G. D. Searle & Co. | Method of producing mouse and human endostatin |
| US20020055467A1 (en) | 1998-07-06 | 2002-05-09 | Johansen Teit E. | Novel neurotrophic factors |
| US6593133B1 (en) | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
| US7067473B1 (en) | 1998-07-14 | 2006-06-27 | Janssen Pharmaceutica N.V. | Neurotrophic growth factor |
| HK1045528B (zh) | 1998-07-14 | 2006-10-27 | 詹森药业有限公司 | 神经营养生长因子 |
| AU778998B2 (en) | 1998-09-22 | 2004-12-23 | University Of Maryland At Baltimore | Cystine knot growth factor mutants |
| US6284540B1 (en) * | 1998-09-29 | 2001-09-04 | Washington University | Artemin, a novel neurotrophic factor |
| US6361771B1 (en) | 1999-04-06 | 2002-03-26 | Neurotech S.A. | ARPE-19 as a platform cell line for encapsulated cell-based delivery |
| EP1175235A1 (de) | 1999-04-22 | 2002-01-30 | Eidgenossisch Technische Hochschule Zurich | Modifizierte proteinmatrizen |
| PT1223966E (pt) | 1999-10-29 | 2003-09-30 | Biopharm Ges Biotechn Entwickl | Utilizacao do gdnf para tratamento de defeitos na cornea |
| CA2327208A1 (en) | 2000-11-30 | 2002-05-30 | The Government Of The United States Of America | Methods of increasing distribution of therapeutic agents |
| IL140110A0 (en) * | 2000-12-05 | 2002-02-10 | Applied Research Systems | Improvement of homogeneity and secretion of recombinant proteins in mammalian systems |
| NZ526610A (en) | 2000-12-22 | 2009-08-28 | Genentech Inc | New use of artemin, a member of the GDNF ligand family |
| SK288123B6 (sk) | 2001-02-01 | 2013-09-03 | Biogen Idec Ma Inc. | Polymer conjugates of neublastin and methods of using same |
| US7442370B2 (en) | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
| US7276580B2 (en) | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
| AU2002250203B2 (en) * | 2001-03-28 | 2006-08-10 | Biogen Ma Inc. | Use of neublastin polypeptides for treating neuropathic pain |
| US20040077543A1 (en) | 2001-03-28 | 2004-04-22 | Sah Dinah W. Y. | Treatment using neublastin polypeptides |
| EP1389121B1 (de) | 2001-04-24 | 2012-02-22 | Purdue Research Foundation | Verfahren und zusammensetzungen zur behandlung von nervengewebeverletzungen in säugetieren |
| US7135334B2 (en) | 2001-06-20 | 2006-11-14 | Genentech, Inc. | PRO20044 nucleic acids |
| US20040028613A1 (en) | 2001-06-25 | 2004-02-12 | Nastech Pharmaceutical Company Inc | Dopamine agonist formulations for enhanced central nervous system delivery |
| US7129085B2 (en) | 2001-10-11 | 2006-10-31 | Bristol-Myers Squibb Company | Polynucleotides encoding a human leucine-rich repeat domain containing protein, HLLRCR-1 |
| GB0205022D0 (en) | 2002-03-04 | 2002-04-17 | Univ Cambridge Tech | Materials and methods for the treatment of cns damage |
| JP4310608B2 (ja) | 2002-04-25 | 2009-08-12 | 東洋紡績株式会社 | Hsp70ファミリータンパク質基質結合ドメインフラグメントの利用方法 |
| ATE433759T1 (de) | 2003-04-18 | 2009-07-15 | Biogen Idec Inc | Polymerkonjugiertes glycosiliertes neublastin |
| RU2005138368A (ru) | 2003-06-10 | 2006-07-27 | ЭнЭсДЖЕНЕ А/С (DK) | Улучшенная секреция нейбластина |
| US7598059B2 (en) | 2003-10-02 | 2009-10-06 | Biogen Idec Ma Inc. | Neublastin expression constructs |
| WO2005072764A2 (en) | 2004-01-16 | 2005-08-11 | Novocell, Inc. | Fibrin-bound angiogenic factors to stimulate vascularization of transplant site of encapsulated cells |
| EP1784486B1 (de) | 2004-06-23 | 2011-10-05 | TissueGene, Inc. | Nervenregeneration |
| US7598356B2 (en) | 2004-07-08 | 2009-10-06 | Board of Regents of the University of Nebraska by and on behalf of the University of Nebraska Medical Center | Method for purifying a protein of the cystine-knot superfamily |
| EP2335713A3 (de) | 2004-08-19 | 2011-11-02 | Biogen Idec MA Inc. | Neublastinvarianten |
| JP4959566B2 (ja) | 2004-08-19 | 2012-06-27 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | トランスホーミング増殖因子βファミリータンパク質の折りたたみ |
| EP1937295A2 (de) | 2005-10-11 | 2008-07-02 | NS Gene A/S | Behandlung von retinopathien mit gfr3-agonisten |
| TWI501774B (zh) | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
| WO2007103182A2 (en) | 2006-03-01 | 2007-09-13 | Biogen Idec Ma Inc. | Compostions and methods for administering gdnf ligand family proteins |
| PT2019683T (pt) | 2006-04-25 | 2017-03-17 | Univ California | Administração de fatores de crescimento para o tratamento de distúrbios do snc |
| JP5583005B2 (ja) | 2007-05-01 | 2014-09-03 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 血管新生を増大させるための組成物および方法 |
-
2004
- 2004-04-16 AT AT07012662T patent/ATE433759T1/de not_active IP Right Cessation
- 2004-04-16 EP EP07012662A patent/EP1897552B1/de not_active Expired - Lifetime
- 2004-04-16 ES ES04750200.0T patent/ES2479942T3/es not_active Expired - Lifetime
- 2004-04-16 WO PCT/US2004/011745 patent/WO2004094592A2/en not_active Ceased
- 2004-04-16 EP EP04750200.0A patent/EP1618179B1/de not_active Expired - Lifetime
- 2004-04-16 ES ES07012662T patent/ES2328640T3/es not_active Expired - Lifetime
- 2004-04-16 CA CA2522364A patent/CA2522364C/en not_active Expired - Fee Related
- 2004-04-16 JP JP2006510112A patent/JP4742030B2/ja not_active Expired - Fee Related
- 2004-04-16 NZ NZ543365A patent/NZ543365A/en not_active IP Right Cessation
- 2004-04-16 CA CA2864810A patent/CA2864810A1/en not_active Abandoned
- 2004-04-16 US US10/553,710 patent/US8163875B2/en not_active Expired - Fee Related
- 2004-04-16 AU AU2004233079A patent/AU2004233079B2/en not_active Ceased
- 2004-04-16 NZ NZ574121A patent/NZ574121A/en not_active IP Right Cessation
- 2004-04-16 DK DK07012662T patent/DK1897552T3/da active
- 2004-04-16 EP EP10182913A patent/EP2322205A1/de not_active Withdrawn
- 2004-04-16 DE DE602004021648T patent/DE602004021648D1/de not_active Expired - Lifetime
-
2010
- 2010-12-06 JP JP2010271994A patent/JP5415392B2/ja not_active Expired - Fee Related
-
2012
- 2012-03-21 US US13/425,583 patent/US8642732B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004233079A1 (en) | 2004-11-04 |
| EP1618179A4 (de) | 2008-03-05 |
| US20070238650A1 (en) | 2007-10-11 |
| US20120316109A1 (en) | 2012-12-13 |
| US8163875B2 (en) | 2012-04-24 |
| ES2328640T3 (es) | 2009-11-16 |
| NZ543365A (en) | 2009-02-28 |
| AU2004233079B2 (en) | 2009-09-17 |
| CA2522364A1 (en) | 2004-11-04 |
| JP5415392B2 (ja) | 2014-02-12 |
| JP2011084567A (ja) | 2011-04-28 |
| EP1897552A1 (de) | 2008-03-12 |
| DK1897552T3 (da) | 2009-10-05 |
| EP1618179A2 (de) | 2006-01-25 |
| NZ574121A (en) | 2011-06-30 |
| WO2004094592A2 (en) | 2004-11-04 |
| JP4742030B2 (ja) | 2011-08-10 |
| EP2322205A1 (de) | 2011-05-18 |
| CA2522364C (en) | 2014-12-09 |
| DE602004021648D1 (de) | 2009-07-30 |
| US8642732B2 (en) | 2014-02-04 |
| EP1618179B1 (de) | 2014-05-07 |
| EP1897552B1 (de) | 2009-06-17 |
| ES2479942T3 (es) | 2014-07-25 |
| JP2006523709A (ja) | 2006-10-19 |
| CA2864810A1 (en) | 2004-11-04 |
| WO2004094592A3 (en) | 2006-04-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE433759T1 (de) | Polymerkonjugiertes glycosiliertes neublastin | |
| EP2298331A3 (de) | Verwendung von Transthyretinpeptid-/-proteinfusionen zur Erhöhung der Serumshalbwertszeit von pharmakologisch aktiven Peptiden/Proteinen | |
| PT1288223E (pt) | Derivados de peptidos terapeuticos | |
| EA200200017A1 (ru) | Терапевтическое средство с ботулиническим нейротоксином | |
| WO2002010195A3 (en) | Modified peptides with increased potency | |
| LU93265I2 (fr) | Eftrénonacog alfa ou un produit biosimilaire conformément à l'article 10(4) de la directive 2001/83/CE, tel que protégé par le brevet de base | |
| EP0695171A1 (de) | Gonadotropin enthaltende gefriergetrocknete troepfen | |
| IL157446A0 (en) | Increased recovery of active proteins | |
| BRPI0417916A (pt) | proteìna de fusão de fc-eritropoietina com farmacocinética melhorada | |
| WO2000018921A3 (en) | Synthetic peptides having fgf receptor affinity | |
| WO2004069176A3 (en) | Polymer conjugates of mutated neublastin | |
| CA2155185A1 (en) | Totally synthetic affinity reagents | |
| BR0314092A (pt) | proteìnas de fusão de transferrina modificadas | |
| ES2193197T3 (es) | Craquizacion catalitica com mcm-49. | |
| CA2077590A1 (en) | Recombinant dna coding for a protein with endochitinase activity | |
| AU2002355742A1 (en) | Crfr1 selective ligands | |
| MXPA05008168A (es) | Conjugados de polimero de neublastina mutada. | |
| DK0382268T3 (da) | Aminocarboxylsyrederivater | |
| WO2002016929A3 (en) | Urokinase peptide structure mimetics | |
| ES1006455U (es) | Elemento de valla. | |
| WO2005078076A3 (en) | Tpl2 and its expression |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |