MC1330A1 - Acetophenones substituees,procede pour leur preparation et agents antiviraux contenant ces composes - Google Patents

Acetophenones substituees,procede pour leur preparation et agents antiviraux contenant ces composes

Info

Publication number
MC1330A1
MC1330A1 MC801451A MC1451A MC1330A1 MC 1330 A1 MC1330 A1 MC 1330A1 MC 801451 A MC801451 A MC 801451A MC 1451 A MC1451 A MC 1451A MC 1330 A1 MC1330 A1 MC 1330A1
Authority
MC
Monaco
Prior art keywords
radical
formula
substituted
hydroxy
dimethoxy
Prior art date
Application number
MC801451A
Other languages
English (en)
French (fr)
Inventor
H Ishitsuka
I Umeda
Y Huhara
N Shinma
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC1330A1 publication Critical patent/MC1330A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/12Esters of phosphoric acids with hydroxyaryl compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06Benzopyran radicals
    • C07H17/065Benzo[b]pyrans
    • C07H17/07Benzo[b]pyran-4-ones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
MC801451A 1979-05-23 1980-05-23 Acetophenones substituees,procede pour leur preparation et agents antiviraux contenant ces composes MC1330A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7917973 1979-05-23

Publications (1)

Publication Number Publication Date
MC1330A1 true MC1330A1 (fr) 1981-04-21

Family

ID=10505387

Family Applications (1)

Application Number Title Priority Date Filing Date
MC801451A MC1330A1 (fr) 1979-05-23 1980-05-23 Acetophenones substituees,procede pour leur preparation et agents antiviraux contenant ces composes

Country Status (25)

Country Link
US (1) US4327088A (xx)
EP (1) EP0021000B1 (xx)
JP (1) JPS55157534A (xx)
AR (1) AR230064A1 (xx)
AT (1) ATE6357T1 (xx)
AU (1) AU538581B2 (xx)
BR (1) BR8003235A (xx)
CA (1) CA1137082A (xx)
CS (1) CS212716B2 (xx)
CU (1) CU35266A (xx)
DE (1) DE3066676D1 (xx)
DK (1) DK224980A (xx)
ES (1) ES491728A0 (xx)
FI (1) FI67556C (xx)
GR (1) GR67305B (xx)
HU (1) HU184288B (xx)
IE (1) IE49816B1 (xx)
IL (1) IL60115A (xx)
MC (1) MC1330A1 (xx)
NO (1) NO152898C (xx)
NZ (1) NZ193750A (xx)
PH (1) PH16056A (xx)
PT (1) PT71289B (xx)
YU (1) YU140280A (xx)
ZA (1) ZA802927B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6385526A (ja) * 1986-09-30 1988-04-16 Nippon Oil & Fats Co Ltd 非線形光学材料
AU635156B2 (en) * 1990-09-20 1993-03-11 Merrell Dow Pharmaceuticals Inc. Calcium uptake inhibitors
IL118657A0 (en) * 1996-06-14 1996-10-16 Arad Dorit Inhibitors for picornavirus proteases
IL122591A0 (en) 1997-12-14 1998-06-15 Arad Dorit Pharmaceutical compositions comprising cystein protease inhibitors
AU3213200A (en) 1999-01-21 2000-08-07 Board Of Regents, The University Of Texas System Inhibitors of intestinal apical membrane na/phosphate co-transportation
US20030162753A1 (en) * 1999-01-21 2003-08-28 Peerce Brian E. Inhibition of intestinal apical membrane Na/phosphate co-transportation in humans
EP1682486A1 (en) * 2003-10-31 2006-07-26 Lica Pharmaceuticals A/S Quaternary amino-functional chalcones
US20060270614A1 (en) * 2005-05-24 2006-11-30 Sekhar Boddupalli Use of chalcones for the treatment of viral disorders
CN119330860B (zh) * 2024-09-09 2025-10-24 中国农业科学院兰州畜牧与兽药研究所 一种双氨基胍类衍生物及其制备方法和应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL102449C (xx) * 1949-11-30
GB1007332A (en) * 1960-12-09 1965-10-13 Cooper Mcdougall & Robertson New halogen-containing phosphoric and thiophosphoric acid esters and formulations containing them
FR1476531A (fr) 1965-04-26 1967-04-14 Chimetron Sarl Nouvelles cétones halogénées dérivées du benzimidazole
US3583894A (en) * 1968-03-29 1971-06-08 Us Agriculture Enzyme preparation of hesperetin dihydrochalcone glucoside
US3629322A (en) * 1969-02-17 1971-12-21 Buckman Labor Inc Organic esters and their use as ultraviolet light absorbers and as heat stabilizers
GB1283981A (en) * 1969-03-05 1972-08-02 Orsymonde 2,4,6-trihydroxy chalcone derivatives
GB1398528A (en) * 1971-08-17 1975-06-25 Leo Ab Pharmaceutically active secondary phosphoric acid esters
JPS598250B2 (ja) * 1974-02-09 1984-02-23 大正製薬株式会社 カルコンエ−テルの合成法
JPS598249B2 (ja) * 1974-01-19 1984-02-23 大正製薬株式会社 カルコン類の合成法
JPS5912094B2 (ja) * 1974-01-19 1984-03-21 大正製薬株式会社 カルコン体の合成法
JPS598251B2 (ja) * 1974-04-19 1984-02-23 大正製薬株式会社 イソプレニルカルコン類の合成法
JPS593460B2 (ja) * 1974-04-19 1984-01-24 大正製薬株式会社 カルコンルイ ノ ゴウセイホウ
JPS50140430A (xx) * 1974-04-23 1975-11-11
FR2307820A1 (fr) * 1975-04-17 1976-11-12 Hayashibara Seibutsu Chem Inst Glycosides d'echinatine et leur preparation
DD123466A1 (xx) 1975-12-01 1976-12-20
US4122191A (en) * 1976-12-20 1978-10-24 Richardson-Merrell Inc. Antirhinovirus agents
US4154756A (en) * 1977-12-15 1979-05-15 American Cyanamid Company 2-Substituted-4'-(monoalkylamino)-acetophenones
NZ192641A (en) * 1979-01-26 1984-10-19 Hoffmann La Roche Substituted acetophenones and pharmaceutical compositions

Also Published As

Publication number Publication date
IL60115A (en) 1986-02-28
ATE6357T1 (de) 1984-03-15
FI67556B (fi) 1984-12-31
DK224980A (da) 1980-11-24
HU184288B (en) 1984-07-30
EP0021000A3 (en) 1981-12-02
CS212716B2 (en) 1982-03-26
FI67556C (fi) 1985-04-10
US4327088A (en) 1982-04-27
FI801661A7 (fi) 1980-11-21
AU538581B2 (en) 1984-08-23
PH16056A (en) 1983-06-09
NZ193750A (en) 1984-12-14
NO152898B (no) 1985-09-02
ES8104812A1 (es) 1981-04-01
PT71289A (en) 1980-06-01
CA1137082A (en) 1982-12-07
YU140280A (en) 1983-12-31
DE3066676D1 (en) 1984-03-29
IE801068L (en) 1980-11-23
ZA802927B (en) 1982-01-27
EP0021000A2 (de) 1981-01-07
NO801542L (no) 1980-11-24
IL60115A0 (en) 1980-07-31
EP0021000B1 (de) 1984-02-22
IE49816B1 (en) 1985-12-25
GR67305B (xx) 1981-06-29
AR230064A1 (es) 1984-02-29
ES491728A0 (es) 1981-04-01
BR8003235A (pt) 1980-12-30
PT71289B (en) 1981-09-21
AU5846580A (en) 1980-11-27
NO152898C (no) 1985-12-11
CU35266A (en) 1982-03-28
JPS55157534A (en) 1980-12-08

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