MA52421A - Composés pharmaceutiques - Google Patents
Composés pharmaceutiquesInfo
- Publication number
- MA52421A MA52421A MA052421A MA52421A MA52421A MA 52421 A MA52421 A MA 52421A MA 052421 A MA052421 A MA 052421A MA 52421 A MA52421 A MA 52421A MA 52421 A MA52421 A MA 52421A
- Authority
- MA
- Morocco
- Prior art keywords
- pharmaceutical compounds
- pharmaceutical
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1803439.7A GB201803439D0 (en) | 2018-03-02 | 2018-03-02 | Pharmaceutical compounds |
GBGB1814135.8A GB201814135D0 (en) | 2018-08-30 | 2018-08-30 | Pharmaceutical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
MA52421A true MA52421A (fr) | 2021-01-06 |
Family
ID=65911230
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA052421A MA52421A (fr) | 2018-03-02 | 2019-03-01 | Composés pharmaceutiques |
Country Status (18)
Country | Link |
---|---|
US (1) | US11466016B2 (fr) |
EP (1) | EP3759111A1 (fr) |
JP (1) | JP7326305B2 (fr) |
KR (1) | KR20200127005A (fr) |
CN (1) | CN111902415A (fr) |
AU (1) | AU2019226480B2 (fr) |
BR (1) | BR112020017283A2 (fr) |
CA (1) | CA3092011A1 (fr) |
IL (1) | IL276232B2 (fr) |
MA (1) | MA52421A (fr) |
MX (1) | MX2020008754A (fr) |
NZ (1) | NZ766835A (fr) |
PH (1) | PH12020551305A1 (fr) |
RU (1) | RU2020130228A (fr) |
SG (1) | SG11202006778TA (fr) |
TW (1) | TW202000667A (fr) |
WO (1) | WO2019167000A1 (fr) |
ZA (1) | ZA202004729B (fr) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11466017B2 (en) | 2011-03-10 | 2022-10-11 | Board Of Regents, The University Of Texas System | Heterocyclic inhibitors of PTPN11 |
EP3463343B1 (fr) | 2016-05-31 | 2022-03-23 | Board of Regents, The University of Texas System | Inhibiteurs hétérocycliques de ptpn11 |
EP3464272B1 (fr) | 2016-06-07 | 2021-12-08 | Jacobio Pharmaceuticals Co., Ltd. | Nouveaux dérivés hétérocycliques utiles en tant qu'inhibiteurs de shp2 |
US11529347B2 (en) | 2016-09-22 | 2022-12-20 | Relay Therapeutics, Inc. | SHP2 phosphatase inhibitors and methods of use thereof |
TW201819386A (zh) | 2016-10-24 | 2018-06-01 | 美商傳達治療有限公司 | Shp2磷酸酶抑制劑及其使用方法 |
AU2018239542C1 (en) | 2017-03-23 | 2021-02-11 | Jacobio Pharmaceuticals Co., Ltd. | Novel heterocyclic derivatives useful as SHP2 inhibitors |
US11591336B2 (en) | 2017-05-26 | 2023-02-28 | D. E. Shaw Research, Llc | Substituted pyrazolo[3,4-b]pyrazines as SHP2 phosphatase inhibitors |
EP3687997A1 (fr) | 2017-09-29 | 2020-08-05 | Relay Therapeutics, Inc. | Dérivés de pyrazolo[3,4-b]pyrazine utilisés en tant qu'inhibiteurs de la phosphatase shp2 |
NZ766835A (en) | 2018-03-02 | 2023-09-29 | Otsuka Pharma Co Ltd | Pharmaceutical compounds |
CN112166110B (zh) | 2018-03-21 | 2023-08-11 | 传达治疗有限公司 | Shp2磷酸酶抑制剂及其使用方法 |
IL278297B2 (en) | 2018-05-02 | 2023-12-01 | Navire Pharma Inc | Transmutable heterocyclic PTPN11 inhibitors |
MX2021000795A (es) * | 2018-07-24 | 2021-04-12 | Taiho Pharmaceutical Co Ltd | Compuestos heterociclicos para inhibir la actividad de shp2. |
BR112021002327A2 (pt) | 2018-08-10 | 2021-05-04 | Navire Pharma, Inc. | derivados de 6-(4-amino-3-metil-2-oxa-8-azaespiro[4,5]decan-8-il)-3-(2,3-diclorofenil)-2-metilpirimidin-4(3h)-ona e compostos relacionados como inibidores de ptpn11(shp2) para o tratamento do câncer |
CA3113233A1 (fr) | 2018-09-18 | 2020-03-26 | Nikang Therapeutics, Inc. | Derives d'anneaux tricycliques fusionnes utilises en tant qu'inhibiteurs de la phosphatase src a homologie-2 |
WO2020072656A1 (fr) | 2018-10-03 | 2020-04-09 | Gilead Sciences, Inc. | Dérivés d'imidozopyrimidine |
TW202116773A (zh) * | 2019-07-04 | 2021-05-01 | 英屬開曼群島商百濟神州有限公司 | 作為HPK1抑制劑之吡咯并[2,3-b]吡及其用途 |
US20220402916A1 (en) | 2019-09-18 | 2022-12-22 | Merck Sharp & Dohme Corp. | Small molecule inhibitors of kras g12c mutant |
AU2020354475A1 (en) | 2019-09-24 | 2022-05-05 | Relay Therapeutics, Inc. | SHP2 phosphatase inhibitors and methods of making and using the same |
CR20220230A (es) | 2019-10-28 | 2022-06-15 | Merck Sharp & Dohme | Inhibidores de pequeñas moléculas de mutante g12c de kras |
WO2021085653A1 (fr) | 2019-10-31 | 2021-05-06 | Taiho Pharmaceutical Co., Ltd. | Dérivés de 4-aminobut-2-enamide et sels de ces derniers |
BR112022008858A2 (pt) | 2019-11-08 | 2022-09-06 | Revolution Medicines Inc | Composto, composição farmacêutica e métodos para inibir sos1 em um sujeito, para inibir a interação de sos1 e uma proteína, para tratar ou prevenir uma doença e para tratar ou prevenir câncer |
WO2021106231A1 (fr) | 2019-11-29 | 2021-06-03 | Taiho Pharmaceutical Co., Ltd. | Composé ayant une activité inhibitrice contre la mutation kras g12d |
US20230181536A1 (en) | 2020-04-24 | 2023-06-15 | Taiho Pharmaceutical Co., Ltd. | Anticancer combination therapy with n-(1-acryloyl-azetidin-3-yl)-2-((1h-indazol-3-yl)amino)methyl)-1h-imidazole-5-carboxamide inhibitor of kras-g12c |
US20230174518A1 (en) | 2020-04-24 | 2023-06-08 | Taiho Pharmaceutical Co., Ltd. | Kras g12d protein inhibitors |
IL299131A (en) | 2020-06-18 | 2023-02-01 | Revolution Medicines Inc | Methods for delaying, preventing and treating acquired resistance to RAS inhibitors |
EP4183395A1 (fr) | 2020-07-15 | 2023-05-24 | Taiho Pharmaceutical Co., Ltd. | Combinaison contenant un composé pyrimidine destinée à être utilisée dans le traitement de tumeurs |
WO2022060583A1 (fr) | 2020-09-03 | 2022-03-24 | Revolution Medicines, Inc. | Utilisation d'inhibiteurs de sos1 pour traiter des malignités à mutations de shp2 |
US11690915B2 (en) | 2020-09-15 | 2023-07-04 | Revolution Medicines, Inc. | Ras inhibitors |
WO2022232320A1 (fr) * | 2021-04-27 | 2022-11-03 | Merck Sharp & Dohme Corp. | Inhibiteurs à petites molécules de mutant de kras g12c |
AR125782A1 (es) | 2021-05-05 | 2023-08-16 | Revolution Medicines Inc | Inhibidores de ras |
JP2024516450A (ja) | 2021-05-05 | 2024-04-15 | レボリューション メディシンズ インコーポレイテッド | 共有結合性ras阻害剤及びその使用 |
WO2022235870A1 (fr) | 2021-05-05 | 2022-11-10 | Revolution Medicines, Inc. | Inhibiteurs de ras pour le traitement du cancer |
CN115340545A (zh) * | 2021-05-14 | 2022-11-15 | 浙江海正药业股份有限公司 | 双环杂芳基类衍生物及其制备方法和用途 |
WO2022250170A1 (fr) | 2021-05-28 | 2022-12-01 | Taiho Pharmaceutical Co., Ltd. | Petites molécules inhibitrices de protéines mutées par kras |
AR127308A1 (es) | 2021-10-08 | 2024-01-10 | Revolution Medicines Inc | Inhibidores ras |
WO2023168036A1 (fr) | 2022-03-04 | 2023-09-07 | Eli Lilly And Company | Procédé de traitement comprenant des inhibiteurs de kras g12c et des inhibiteurs de shp2 |
WO2023172940A1 (fr) | 2022-03-08 | 2023-09-14 | Revolution Medicines, Inc. | Méthodes de traitement du cancer du poumon réfractaire immunitaire |
WO2023240263A1 (fr) | 2022-06-10 | 2023-12-14 | Revolution Medicines, Inc. | Inhibiteurs de ras macrocycliques |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005099688A2 (fr) | 2004-04-07 | 2005-10-27 | Takeda Pharmaceutical Company Limited | Composes cycliques |
RU2394825C2 (ru) | 2004-11-22 | 2010-07-20 | Вертекс Фармасьютикалз Инкорпорейтед | Пирролопиразины, пригодные в качестве ингибиторов киназы аврора а |
CN102311447B (zh) | 2010-07-07 | 2013-11-27 | 中国科学院广州生物医药与健康研究院 | 杂环并嘧啶酮类dpp-iv抑制剂 |
WO2013063214A1 (fr) | 2011-10-27 | 2013-05-02 | Merck Sharp & Dohme Corp. | Nouveaux composés qui sont des inhibiteurs d'erk |
CN105899491B (zh) | 2014-01-17 | 2019-04-02 | 诺华股份有限公司 | 用于抑制shp2活性的1-哒嗪-/三嗪-3-基-哌(-嗪)/啶/吡咯烷衍生物及其组合物 |
JO3517B1 (ar) | 2014-01-17 | 2020-07-05 | Novartis Ag | ان-ازاسبيرو الكان حلقي كبديل مركبات اريل-ان مغايرة وتركيبات لتثبيط نشاط shp2 |
EP3094629B1 (fr) | 2014-01-17 | 2018-08-22 | Novartis AG | Dérivés de 1-(triazin-3-yl/pyridazin-3-yl)-piper(-azine)idine et compositions les contenant pour l'inhibition de l'activité de shp2 |
US10287266B2 (en) | 2015-06-19 | 2019-05-14 | Novartis Ag | Compounds and compositions for inhibiting the activity of SHP2 |
JP6878316B2 (ja) | 2015-06-19 | 2021-05-26 | ノバルティス アーゲー | Shp2の活性を阻害するための化合物および組成物 |
WO2016203404A1 (fr) * | 2015-06-19 | 2016-12-22 | Novartis Ag | Composés et compositions pour inhiber l'activité de shp2 |
CN107709327A (zh) | 2015-06-22 | 2018-02-16 | 小野药品工业株式会社 | Brk抑制性化合物 |
WO2017156397A1 (fr) | 2016-03-11 | 2017-09-14 | Board Of Regents, The University Of Texas Sysytem | Inhibiteurs hétérocycliques de ptpn11 |
EP3463343B1 (fr) * | 2016-05-31 | 2022-03-23 | Board of Regents, The University of Texas System | Inhibiteurs hétérocycliques de ptpn11 |
EP3464272B1 (fr) | 2016-06-07 | 2021-12-08 | Jacobio Pharmaceuticals Co., Ltd. | Nouveaux dérivés hétérocycliques utiles en tant qu'inhibiteurs de shp2 |
WO2017216706A1 (fr) | 2016-06-14 | 2017-12-21 | Novartis Ag | Composés et compositions pour l'inhibition de l'activité de shp2 |
US11529347B2 (en) | 2016-09-22 | 2022-12-20 | Relay Therapeutics, Inc. | SHP2 phosphatase inhibitors and methods of use thereof |
TW201819386A (zh) | 2016-10-24 | 2018-06-01 | 美商傳達治療有限公司 | Shp2磷酸酶抑制劑及其使用方法 |
ES2964956T3 (es) | 2017-01-10 | 2024-04-10 | Novartis Ag | Combinación farmacéutica que comprende un inhibidor de ALK y un inhibidor de SHP2 |
GB201706327D0 (en) | 2017-04-20 | 2017-06-07 | Otsuka Pharma Co Ltd | A pharmaceutical compound |
US11591336B2 (en) | 2017-05-26 | 2023-02-28 | D. E. Shaw Research, Llc | Substituted pyrazolo[3,4-b]pyrazines as SHP2 phosphatase inhibitors |
CA3074690A1 (fr) | 2017-09-07 | 2019-03-14 | Revolution Medicines, Inc. | Compositions d'inhibiteur de la shp2 et methodes de traitement du cancer |
KR20200099530A (ko) | 2017-12-15 | 2020-08-24 | 레볼루션 메디슨즈, 인크. | 알로스테릭 shp2 억제제로서의 다환식 화합물 |
EP3755699A1 (fr) | 2018-02-21 | 2020-12-30 | Relay Therapeutics, Inc. | Inhibiteurs de la protéine shp2 phosphatase et leurs procédés d'utilisation |
NZ766835A (en) | 2018-03-02 | 2023-09-29 | Otsuka Pharma Co Ltd | Pharmaceutical compounds |
CN112368272B (zh) | 2018-03-21 | 2023-04-21 | 苏州浦合医药科技有限公司 | Shp2抑制剂及其用途 |
EP3768680A1 (fr) | 2018-03-21 | 2021-01-27 | Relay Therapeutics, Inc. | Inhibiteurs de la phosphatase pyrazolo[3,4-b]pyrazine shp2 et leurs procédés d'utilisation |
IL278297B2 (en) | 2018-05-02 | 2023-12-01 | Navire Pharma Inc | Transmutable heterocyclic PTPN11 inhibitors |
MX2021000795A (es) | 2018-07-24 | 2021-04-12 | Taiho Pharmaceutical Co Ltd | Compuestos heterociclicos para inhibir la actividad de shp2. |
EP3856345A1 (fr) | 2018-09-29 | 2021-08-04 | Novartis AG | Procédé de fabrication d'un composé pour inhiber l'activité de shp2 |
CA3112322A1 (fr) | 2018-09-29 | 2020-04-02 | Novartis Ag | Fabrication de composes et de compositions pour inhiber l'activite de shp2 |
GB201911928D0 (en) | 2019-08-20 | 2019-10-02 | Otsuka Pharma Co Ltd | Pharmaceutical compounds |
WO2021149817A1 (fr) | 2020-01-24 | 2021-07-29 | Taiho Pharmaceutical Co., Ltd. | Amélioration de l'activité anti-tumorale de la pyrimidinone inhibitrice de shp2 en association avec de nouveaux médicaments anti-cancéreux contre le cancer |
-
2019
- 2019-03-01 NZ NZ766835A patent/NZ766835A/en unknown
- 2019-03-01 JP JP2020544607A patent/JP7326305B2/ja active Active
- 2019-03-01 US US16/976,631 patent/US11466016B2/en active Active
- 2019-03-01 MX MX2020008754A patent/MX2020008754A/es unknown
- 2019-03-01 IL IL276232A patent/IL276232B2/en unknown
- 2019-03-01 WO PCT/IB2019/051641 patent/WO2019167000A1/fr active Application Filing
- 2019-03-01 RU RU2020130228A patent/RU2020130228A/ru unknown
- 2019-03-01 SG SG11202006778TA patent/SG11202006778TA/en unknown
- 2019-03-01 EP EP19713584.1A patent/EP3759111A1/fr active Pending
- 2019-03-01 BR BR112020017283-9A patent/BR112020017283A2/pt unknown
- 2019-03-01 CN CN201980022127.4A patent/CN111902415A/zh active Pending
- 2019-03-01 CA CA3092011A patent/CA3092011A1/fr active Pending
- 2019-03-01 MA MA052421A patent/MA52421A/fr unknown
- 2019-03-01 AU AU2019226480A patent/AU2019226480B2/en active Active
- 2019-03-01 KR KR1020207027598A patent/KR20200127005A/ko not_active Application Discontinuation
- 2019-03-04 TW TW108107099A patent/TW202000667A/zh unknown
-
2020
- 2020-07-30 ZA ZA2020/04729A patent/ZA202004729B/en unknown
- 2020-08-13 PH PH12020551305A patent/PH12020551305A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
PH12020551305A1 (en) | 2021-10-25 |
TW202000667A (zh) | 2020-01-01 |
AU2019226480A1 (en) | 2020-08-27 |
US11466016B2 (en) | 2022-10-11 |
RU2020130228A (ru) | 2022-04-04 |
CA3092011A1 (fr) | 2019-09-06 |
KR20200127005A (ko) | 2020-11-09 |
WO2019167000A1 (fr) | 2019-09-06 |
IL276232B1 (en) | 2023-12-01 |
JP7326305B2 (ja) | 2023-08-15 |
MX2020008754A (es) | 2020-12-07 |
EP3759111A1 (fr) | 2021-01-06 |
IL276232B2 (en) | 2024-04-01 |
AU2019226480B2 (en) | 2022-12-15 |
JP2021514962A (ja) | 2021-06-17 |
IL276232A (en) | 2020-09-30 |
US20210107908A1 (en) | 2021-04-15 |
BR112020017283A2 (pt) | 2020-12-15 |
ZA202004729B (en) | 2024-02-28 |
CN111902415A (zh) | 2020-11-06 |
SG11202006778TA (en) | 2020-08-28 |
NZ766835A (en) | 2023-09-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA52421A (fr) | Composés pharmaceutiques | |
MA52948A (fr) | Composés | |
MA51669A (fr) | Composés | |
DK3810587T3 (da) | Substituerede alkoxypyridinylindolsulfonamider | |
MA53003A (fr) | Composés | |
MA50541A (fr) | Formulations pharmaceutiques | |
DK3529240T3 (da) | Farmaceutiske forbindelser | |
MA42303A (fr) | Formulations pharmaceutiques | |
MA46867A (fr) | Formulations pharmaceutiques | |
DK3870578T3 (da) | Terapeutiske forbindelser | |
MA41169A (fr) | Composés antibactériens à large spectre d'activité | |
DK3768669T3 (da) | Piperazinazaspiroderivater | |
MA49837A (fr) | Compositions pharmaceutiques | |
MA45187A (fr) | Combinaisons pharmaceutiques | |
MA49621A (fr) | Composés bifonctionnels | |
MA55015A (fr) | Formulations pharmaceutiques | |
DK3823971T3 (da) | Substituerede triazol-quinoxalin-derivater | |
DE112019002443A5 (de) | Applikator | |
DK3762009T3 (da) | Toxin-afledte indgivelseskonstrukter til oral indgivelse | |
MA52946A (fr) | Composés | |
DK3796975T3 (da) | Sulfonylaminobenzamidderivater | |
MA51221A (fr) | Composés de pyrazolopyridinone | |
DK3886820T3 (da) | Kapselformuleringer | |
MA54095A (fr) | Formulations pharmaceutiques aqueuses | |
DK3996688T3 (da) | Farmaceutisk præparat |