MA39484A - Indazoles à substituants benzyle utilisés comme inhibiteurs de bub1 - Google Patents

Indazoles à substituants benzyle utilisés comme inhibiteurs de bub1

Info

Publication number
MA39484A
MA39484A MA039484A MA39484A MA39484A MA 39484 A MA39484 A MA 39484A MA 039484 A MA039484 A MA 039484A MA 39484 A MA39484 A MA 39484A MA 39484 A MA39484 A MA 39484A
Authority
MA
Morocco
Prior art keywords
indazoles
benzyl substitute
bub1 inhibitors
bub1
inhibitors
Prior art date
Application number
MA039484A
Other languages
English (en)
French (fr)
Inventor
Wilhelm Bone
Hans Briem
Lars Bärfacker
Arwed Cleve
Amaury Ernesto Fernandez-Montalvan
Marion Hitchcock
Simon Holton
Joachim Kuhnke
Hans-Georg Lerchen
Anne Mengel
Ursula Mönning
Manfred Möwes
Thomas Müller
Jens SCHRÖDER
Gerhard Siemeister
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of MA39484A publication Critical patent/MA39484A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
MA039484A 2014-09-19 2015-09-17 Indazoles à substituants benzyle utilisés comme inhibiteurs de bub1 MA39484A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14185604 2014-09-19
EP15176903 2015-07-15

Publications (1)

Publication Number Publication Date
MA39484A true MA39484A (fr) 2016-03-24

Family

ID=54140475

Family Applications (1)

Application Number Title Priority Date Filing Date
MA039484A MA39484A (fr) 2014-09-19 2015-09-17 Indazoles à substituants benzyle utilisés comme inhibiteurs de bub1

Country Status (27)

Country Link
US (1) US10350206B2 (en:Method)
EP (1) EP3194379A1 (en:Method)
JP (1) JP6664385B2 (en:Method)
KR (1) KR20170049604A (en:Method)
CN (1) CN107001331A (en:Method)
AP (1) AP2017009803A0 (en:Method)
AU (1) AU2015316796A1 (en:Method)
BR (1) BR112017005444A2 (en:Method)
CA (1) CA2961589A1 (en:Method)
CL (1) CL2017000654A1 (en:Method)
CO (1) CO2017002532A2 (en:Method)
CR (1) CR20170100A (en:Method)
CU (1) CU20170029A7 (en:Method)
DO (1) DOP2017000078A (en:Method)
EA (1) EA032401B1 (en:Method)
EC (1) ECSP17016797A (en:Method)
IL (1) IL251071A0 (en:Method)
MA (1) MA39484A (en:Method)
MX (1) MX2017003664A (en:Method)
NI (1) NI201700034A (en:Method)
PE (1) PE20170697A1 (en:Method)
PH (1) PH12017500509A1 (en:Method)
SG (1) SG11201702082VA (en:Method)
TN (1) TN2017000092A1 (en:Method)
TW (1) TW201615636A (en:Method)
UY (1) UY36311A (en:Method)
WO (1) WO2016042084A1 (en:Method)

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AR111960A1 (es) 2017-05-26 2019-09-04 Incyte Corp Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
KR20210018265A (ko) 2018-05-04 2021-02-17 인사이트 코포레이션 Fgfr 억제제의 고체 형태 및 이의 제조 방법
MX2020011639A (es) 2018-05-04 2021-02-15 Incyte Corp Sales de un inhibidor de receptores de factor de crecimiento de fibroblastos (fgfr).
WO2020185532A1 (en) 2019-03-08 2020-09-17 Incyte Corporation Methods of treating cancer with an fgfr inhibitor
US11591329B2 (en) 2019-07-09 2023-02-28 Incyte Corporation Bicyclic heterocycles as FGFR inhibitors
WO2021067374A1 (en) 2019-10-01 2021-04-08 Incyte Corporation Bicyclic heterocycles as fgfr inhibitors
JP7675711B2 (ja) 2019-10-14 2025-05-13 インサイト・コーポレイション Fgfr阻害剤としての二環式複素環
WO2021076728A1 (en) 2019-10-16 2021-04-22 Incyte Corporation Bicyclic heterocycles as fgfr inhibitors
WO2021113479A1 (en) 2019-12-04 2021-06-10 Incyte Corporation Tricyclic heterocycles as fgfr inhibitors
CR20220285A (es) 2019-12-04 2022-10-27 Incyte Corp Derivados de un inhibidor de fgfr
WO2021146424A1 (en) 2020-01-15 2021-07-22 Incyte Corporation Bicyclic heterocycles as fgfr inhibitors
JP2024513575A (ja) 2021-04-12 2024-03-26 インサイト・コーポレイション Fgfr阻害剤及びネクチン-4標的化剤を含む併用療法
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Also Published As

Publication number Publication date
US10350206B2 (en) 2019-07-16
UY36311A (es) 2016-04-29
EA032401B1 (ru) 2019-05-31
EP3194379A1 (en) 2017-07-26
CN107001331A (zh) 2017-08-01
CR20170100A (es) 2017-04-24
JP6664385B2 (ja) 2020-03-13
DOP2017000078A (es) 2017-06-30
TN2017000092A1 (en) 2018-07-04
SG11201702082VA (en) 2017-04-27
KR20170049604A (ko) 2017-05-10
MX2017003664A (es) 2017-07-13
WO2016042084A1 (en) 2016-03-24
AU2015316796A1 (en) 2017-03-30
EA201790649A1 (ru) 2017-09-29
CL2017000654A1 (es) 2017-12-11
TW201615636A (zh) 2016-05-01
IL251071A0 (en) 2017-04-30
PH12017500509A1 (en) 2017-08-30
AP2017009803A0 (en) 2017-03-31
US20170273980A1 (en) 2017-09-28
CU20170029A7 (es) 2017-08-08
CA2961589A1 (en) 2016-03-24
BR112017005444A2 (pt) 2018-04-24
CO2017002532A2 (es) 2017-07-11
ECSP17016797A (es) 2017-05-31
JP2017530962A (ja) 2017-10-19
PE20170697A1 (es) 2017-06-24
NI201700034A (es) 2017-06-16

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