MA39347B2 - Protéines de fusion d'uti - Google Patents

Protéines de fusion d'uti

Info

Publication number
MA39347B2
MA39347B2 MA39347A MA39347A MA39347B2 MA 39347 B2 MA39347 B2 MA 39347B2 MA 39347 A MA39347 A MA 39347A MA 39347 A MA39347 A MA 39347A MA 39347 B2 MA39347 B2 MA 39347B2
Authority
MA
Morocco
Prior art keywords
fusion proteins
uti fusion
uti
proteins
producing
Prior art date
Application number
MA39347A
Other languages
English (en)
French (fr)
Other versions
MA39347A1 (fr
Inventor
Aaron Chamberlain
Qiang Liu
Mathias Schmidt
Original Assignee
Takeda Pharmaceuticals Co
Takeda Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co, Takeda Gmbh filed Critical Takeda Pharmaceuticals Co
Publication of MA39347A1 publication Critical patent/MA39347A1/fr
Publication of MA39347B2 publication Critical patent/MA39347B2/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114Kunitz type inhibitors
    • C07K14/8117Bovine/basic pancreatic trypsin inhibitor (BPTI, aprotinin)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114Kunitz type inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/90Fusion polypeptide containing a motif for post-translational modification
    • C07K2319/91Fusion polypeptide containing a motif for post-translational modification containing a motif for glycosylation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
MA39347A 2014-02-24 2015-02-23 Protéines de fusion d'uti MA39347B2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461943617P 2014-02-24 2014-02-24
PCT/US2015/017152 WO2015127391A1 (en) 2014-02-24 2015-02-23 Uti fusion proteins

Publications (2)

Publication Number Publication Date
MA39347A1 MA39347A1 (fr) 2018-06-29
MA39347B2 true MA39347B2 (fr) 2020-05-29

Family

ID=52629709

Family Applications (1)

Application Number Title Priority Date Filing Date
MA39347A MA39347B2 (fr) 2014-02-24 2015-02-23 Protéines de fusion d'uti

Country Status (38)

Country Link
US (4) US9856310B2 (cg-RX-API-DMAC7.html)
EP (2) EP3443978A1 (cg-RX-API-DMAC7.html)
JP (4) JP6574431B2 (cg-RX-API-DMAC7.html)
KR (3) KR102461210B1 (cg-RX-API-DMAC7.html)
CN (2) CN106232135B (cg-RX-API-DMAC7.html)
AR (1) AR101597A1 (cg-RX-API-DMAC7.html)
AU (4) AU2015218704B2 (cg-RX-API-DMAC7.html)
BR (1) BR112016019390B1 (cg-RX-API-DMAC7.html)
CA (2) CA2939639C (cg-RX-API-DMAC7.html)
CL (1) CL2016002136A1 (cg-RX-API-DMAC7.html)
CR (1) CR20160444A (cg-RX-API-DMAC7.html)
CY (1) CY1120997T1 (cg-RX-API-DMAC7.html)
DK (1) DK3110434T3 (cg-RX-API-DMAC7.html)
DO (1) DOP2016000202A (cg-RX-API-DMAC7.html)
EA (2) EA202091567A1 (cg-RX-API-DMAC7.html)
EC (1) ECSP16076535A (cg-RX-API-DMAC7.html)
ES (1) ES2700149T3 (cg-RX-API-DMAC7.html)
GE (1) GEP20196970B (cg-RX-API-DMAC7.html)
HR (1) HRP20182029T1 (cg-RX-API-DMAC7.html)
IL (1) IL247321B (cg-RX-API-DMAC7.html)
JO (1) JO3729B1 (cg-RX-API-DMAC7.html)
LT (1) LT3110434T (cg-RX-API-DMAC7.html)
MA (1) MA39347B2 (cg-RX-API-DMAC7.html)
MX (4) MX384070B (cg-RX-API-DMAC7.html)
MY (1) MY178774A (cg-RX-API-DMAC7.html)
NZ (3) NZ724196A (cg-RX-API-DMAC7.html)
PE (1) PE20170257A1 (cg-RX-API-DMAC7.html)
PH (1) PH12016501629B1 (cg-RX-API-DMAC7.html)
PL (1) PL3110434T3 (cg-RX-API-DMAC7.html)
PT (1) PT3110434T (cg-RX-API-DMAC7.html)
RS (1) RS58285B1 (cg-RX-API-DMAC7.html)
SG (2) SG11201606691QA (cg-RX-API-DMAC7.html)
SI (1) SI3110434T1 (cg-RX-API-DMAC7.html)
SM (1) SMT201800674T1 (cg-RX-API-DMAC7.html)
TW (1) TWI694084B (cg-RX-API-DMAC7.html)
UA (1) UA118866C2 (cg-RX-API-DMAC7.html)
WO (1) WO2015127391A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201606327B (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CR20160444A (es) * 2014-02-24 2017-04-21 Takeda Gmbh Proteínas de fusión uti
PE20251181A1 (es) * 2017-06-07 2025-04-23 Spark Therapeutics Inc Agentes potenciadores para la transfeccion celular mejorada y/o la produccion del vector raav
WO2020106881A1 (en) * 2018-11-20 2020-05-28 Diamedica Inc. Modified ulinastatin polypeptides
JP2021050161A (ja) 2019-09-25 2021-04-01 武田薬品工業株式会社 複素環化合物及びその用途
JP2021080177A (ja) 2019-11-14 2021-05-27 武田薬品工業株式会社 複素環化合物及びその用途
BR112022017718A2 (pt) * 2020-03-05 2022-11-16 Diamedica Usa Inc Polipeptídeos de ulinastatina

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EP0401508B1 (de) * 1989-05-13 1994-11-23 Bayer Ag Proteinaseninhibitoren, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
US5409895A (en) 1990-11-13 1995-04-25 Mochida Pharmaceutical Co., Ltd. Protease inhibitory polypeptides derived from urinary trypsin inhibitor and compositions thereof
JP2769083B2 (ja) 1993-02-22 1998-06-25 日清食品株式会社 エラスターゼ阻害活性を有する新規ペプチドおよびその製造方法
TR199801794T2 (xx) 1996-03-11 2000-07-21 Bayer Corporation �nsan bikunini.
DE19725014A1 (de) 1997-06-13 1998-12-17 Bayer Ag Aprotininvarianten mit verbesserten Eigenschaften und Bikunine von Aprotininvarianten
WO2005095457A2 (en) * 2004-03-30 2005-10-13 Glaxo Group Limited Immunoglobulins
BRPI0514259A (pt) * 2004-08-11 2008-06-03 Trubion Pharmaceuticals Inc proteìna de fusão de domìnio de ligação
CN103665168A (zh) * 2005-06-03 2014-03-26 持田制药株式会社 抗cd14抗体融合蛋白质
EP1981519B1 (en) 2005-12-29 2017-12-27 Dyax Corp. Protease inhibition
CA2737241C (en) * 2008-09-26 2017-08-29 Ucb Pharma S.A. Multivalent antibody fusion proteins
CN102580085B (zh) * 2008-10-13 2013-09-18 成都康弘生物科技有限公司 Vegf受体融合蛋白在制备治疗脓毒症药物中的应用
CN101721699B (zh) * 2008-10-13 2012-11-07 成都康弘生物科技有限公司 Vegf受体融合蛋白在制备治疗伴随vegf升高的炎症反应的药物中的应用
JP2012525847A (ja) * 2009-05-05 2012-10-25 アムジエン・インコーポレーテツド Fgf21変異体およびその使用
PT3053932T (pt) * 2010-02-19 2020-10-21 Xencor Inc Novas imunoadesinas ctla4-ig
SI2704737T1 (en) * 2011-04-29 2018-06-29 University Of Washington Therapeutic nuclease compositions and methods
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JP6138815B2 (ja) * 2011-12-01 2017-05-31 エーピー バイオサイエンシーズ, インコーポレイテッド 補体経路およびvegf経路に対するタンパク質インヒビターおよびそれらの使用方法
BR112014026162A2 (pt) * 2012-04-23 2017-10-03 Nrl Pharma Inc Proteína de fusão ou variante da mesma, molécula de ácido nucleico, vetor de expressão, célula hospedeira, animal não humano geneticamente modificado, planta geneticamente modificada, agente terapêutico para doenças melhoradas por lactoferrina, composição farmacêutica, e, método para preparar a proteína de fusão ou variante da mesma
CN103044554B (zh) 2012-05-14 2014-08-27 旭华(上海)生物研发中心有限公司 重组二聚化人尿胰蛋白酶抑制剂、其制备方法及其应用
JP2013253079A (ja) * 2012-05-14 2013-12-19 Xuhua (Shanghai) Biological Research & Development Center Co Ltd 生物学的に活性なヒト尿中トリプシンインヒビターのFc融合タンパク質並びにその調製および使用
CR20160444A (es) * 2014-02-24 2017-04-21 Takeda Gmbh Proteínas de fusión uti

Also Published As

Publication number Publication date
EP3110434B1 (en) 2018-09-19
ECSP16076535A (es) 2017-08-31
JO3729B1 (ar) 2021-01-31
CN106232135B (zh) 2019-12-10
KR102722304B1 (ko) 2024-10-28
IL247321B (en) 2020-06-30
AU2015218704B2 (en) 2019-05-02
US20160362475A1 (en) 2016-12-15
PE20170257A1 (es) 2017-03-30
JP6574431B2 (ja) 2019-09-11
BR112016019390A2 (pt) 2017-10-24
ZA201606327B (en) 2019-01-30
SG11201606691QA (en) 2016-09-29
CN106232135A (zh) 2016-12-14
MX2019013124A (es) 2020-08-31
BR112016019390B1 (pt) 2023-11-14
CA2939639C (en) 2023-01-24
US20180072795A1 (en) 2018-03-15
JP2023123763A (ja) 2023-09-05
SI3110434T1 (sl) 2019-02-28
PL3110434T3 (pl) 2019-01-31
CA2939639A1 (en) 2015-08-27
HRP20182029T1 (hr) 2019-02-08
MX384070B (es) 2025-03-14
JP6938565B2 (ja) 2021-09-22
KR20240155987A (ko) 2024-10-29
CN110092837B (zh) 2024-01-02
AU2021225156A1 (en) 2021-09-30
UA118866C2 (uk) 2019-03-25
CN110092837A (zh) 2019-08-06
MX2016010950A (es) 2017-04-25
US10351618B2 (en) 2019-07-16
US20220127334A1 (en) 2022-04-28
CY1120997T1 (el) 2019-12-11
WO2015127391A1 (en) 2015-08-27
AU2019204448B2 (en) 2021-06-10
DOP2016000202A (es) 2016-12-15
CR20160444A (es) 2017-04-21
EA037256B1 (ru) 2021-02-26
AU2021225156B2 (en) 2022-11-24
KR20160141718A (ko) 2016-12-09
SG10201708400QA (en) 2017-11-29
MA39347A1 (fr) 2018-06-29
KR102461210B1 (ko) 2022-10-31
GEP20196970B (en) 2019-04-25
MX2024000004A (es) 2024-02-20
IL247321A0 (en) 2016-09-29
KR20220151005A (ko) 2022-11-11
MY178774A (en) 2020-10-20
US20200040062A1 (en) 2020-02-06
EP3443978A1 (en) 2019-02-20
CL2016002136A1 (es) 2017-08-11
SMT201800674T1 (it) 2019-01-11
CA3178241A1 (en) 2015-08-27
JP2017512058A (ja) 2017-05-18
EA201691702A1 (ru) 2017-01-30
AU2023200875A1 (en) 2023-04-27
ES2700149T3 (es) 2019-02-14
PH12016501629B1 (en) 2023-10-20
EA202091567A1 (ru) 2021-07-30
TWI694084B (zh) 2020-05-21
LT3110434T (lt) 2018-12-27
TW201630931A (zh) 2016-09-01
AR101597A1 (es) 2016-12-28
US9856310B2 (en) 2018-01-02
DK3110434T3 (en) 2019-01-14
RS58285B1 (sr) 2019-03-29
PH12016501629A1 (en) 2017-02-06
AU2019204448A1 (en) 2019-07-11
NZ760789A (en) 2023-03-31
NZ760008A (en) 2023-03-31
PT3110434T (pt) 2018-12-19
JP2019187427A (ja) 2019-10-31
JP2022002513A (ja) 2022-01-11
EP3110434A1 (en) 2017-01-04
NZ724196A (en) 2022-01-28
AU2015218704A1 (en) 2016-09-22

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